240 terminated. 240 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 240 | Terminated 240 |
Follow Pain: new trials by email Literature Review of Pain trials Research Report on Pain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Anrikefon-based Patient-controlled Intravenous Analgesia After Laparoscopic Surgery High-dose anrikefon, Medium-dose anrikefon, Low-dose anrikefon - Laparoscopic Surgery, Visceral Pain, Postoperative | Phase 4 | Terminated | Peking University First Hospital | 13 | 2025-12-25 | 2026-04-09 |
| Paracetamol in Addition to WHO Step III Opioids in Chronic Cancer Pain Control Placebo, Paracetamol - Pain | Phase 4 | Terminated | Insel Gruppe AG, University Hospital Bern | 7 | 2024-08-28 | 2026-04-13 |
| Ketamine-assisted Therapy for Advanced GI Cancer Ketamine, Ketamine Injectable Product, Meaning and Purpose therapy - Pancreatic Ductal Adenocarcinoma, Pain, Acute | Phase 4 | Terminated | Brian Anderson, MD | 1 | 2024-05-17 | 2025-05-21 |
| Search to Advance Limited Use of Opioids Pilot: Optimization of Non-Opioid Therapy With a Steroid Dexamethasone 8mg, Placebo - Pain Management | Phase 4 | Terminated | Rutgers, The State University of New Jersey | 8 | 2023-11-27 | 2025-06-04 |
| Evolution of Post-Stroke Shoulder Pain With a Capsular Pattern With Physiotherapy Alone Versus Coupled With Mild Arthrographic Distension With Cortisone Physiotherapy alone, Glenohumeral injection of 40mg (1cc) of Triamcinolone and 7cc of 0.5% Bupivacaine coupled with physiotherapy - Shoulder Pain | Phase 4 | Terminated | Claire Bourgeois | 50 | 2023-05-21 | 2026-03-25 |
| ZYNRELEF for Pain Management in Total Knee Arthroplasty Bupivacaine-Meloxicam 400 Mg-12 Mg/14 mL Injectable Solution, Extended Release - Post Operative Pain, Osteoarthritis, Knee | Phase 4 | Terminated | Baptist Health South Florida | 29 | 2023-03-09 | 2026-05-28 |
| Pregabalin for Central Sensitization in TKA Pregabalin 75mg - Osteo Arthritis Knee, Central Nervous System Sensitization | Phase 4 | Terminated | University of Iowa | 20 | 2023-02-21 | 2025-03-04 |
| Comparing Local Anesthesia With and Without iPACK Block Real iPACK block (20 mL of 0.25% bupivacaine, 2.5mcg/mL epinephrine, and 50mcg/mL preservative-free dexamethasone), Sham iPACK block with 20ml normal saline - Osteo Arthritis Knee, Analgesia | Phase 4 | Terminated | University of Calgary | 10 | 2022-10-30 | 2026-06-01 |
| Randomized Trial of Buprenorphine Microdose Inductions During Hospitalization BUP microdose induction, TAU, Linkage to outpatient BUP treatment - Substance Use Disorders, Opioid-use Disorder | Phase 4 | Terminated | Montefiore Medical Center | 23 | 2022-09-29 | 2026-05-08 |
| Sternotomies and PectoIntercostal Fascia Blocks in Fast-Track Cardiac Anesthesiology Pectointercostal fascia blocks, Placebo - Post-operative Pain | Phase 4 | Terminated | University of Alberta | 1 | 2022-09-22 | 2023-12-18 |
| Liposomal Bupivacaine vs Continuous Nerve Catheters for Below the Knee Amputations Liposomal bupivacaine, Bupivacaine Hydrochloride 0.5 % Injectable Solution - Pain, Postoperative, Amputation | Phase 4 | Terminated | Aurora Quaye | 11 | 2022-08-15 | 2026-01-27 |
| Conventional vs Bipolar SIJ RFA for Treatment of Sacroiliac Joint Pain Nimbus Sacroiliac Joint Radiofrequency Ablation (N-SIJRFA), Conventional Sacroiliac Joint Radiofrequency Ablation (C-SIJRFA) - Sacroiliac Joint Complex, Low Back Pain | Phase 4 | Terminated | University of Utah | 20 | 2022-08-15 | 2026-06-26 |
| Low-dose KETamine as an Adjunct to MOrphine for Acute Pain in the ED low dose ketamine, Placebo (saline) - Acute Pain, Opioid Use | Phase 4 | Terminated | University of Aarhus | 116 | 2022-05-31 | 2023-09-26 |
| Safety and Pharmacokinetics of N1539 in Children 2 to <17 Years of Age Following Surgery N1539 - Post Operative Pain | Phase 4 | Terminated | Baudax Bio | 19 | 2022-02-24 | 2023-09-13 |
| TAP Block Using Liposomal Bupivacaine for Post-cesarean Delivery Analgesia- Walking Towards Recovery Liposomal bupivacaine (LB), Dexamethasone and methylprednisolone (CG), Control group (Bupivacaine)- (BPG) - Opioid Use, Pain, Acute | Phase 4 | Terminated | Yale University | 147 | 2022-02-01 | 2025-03-21 |
| The Effect of Pretreatment With Intravenous Lidocaine for Intravenous Contrast: Preservative Free Lidocaine, Saline - Pain | Phase 4 | Terminated | Antonios Likourezos | 3 | 2022-01-03 | 2025-05-18 |
| Pain Relief After Trapeziectomy: Ibuprofen & Acetaminophen Versus Oxycodone NSAID capsules, Opioid capsule - Pain, Postoperative, Osteoarthritis Thumb | Phase 4 | Terminated | Stanford University | 73 | 2021-12-27 | 2026-10-27 |
| Vital Capacity in Ultrasound Guided Serratus Plane Block in ED Patients With Multiple Rib Fractures Acetaminophen, Bupivacain, Saline - Pain | Phase 4 | Terminated | Antonios Likourezos | 3 | 2021-11-01 | 2024-06-11 |
| Different Dosage Regimens of Methocarbamol/Paracetamol in Acute Non-specific Low Back Pain. MioPain Study 380 mg/300 mg comprimidos metocarbamol/paracetamol - 4 times daily, 380 mg/300 mg comprimidos metocarbamol/paracetamol - 6 times daily - Low Back Pain | Phase 4 | Terminated | Aziende Chimiche Riunite Angelini Francesco S.p.A | 172 | 2021-10-07 | 2025-01-31 |
| Methadone and Medication Abortion Methadone Pill, Ibuprofen - Pain, Medical Abortion | Phase 4 | Terminated | Boston Medical Center | 4 | 2021-10-04 | 2023-01-23 |
Showing 20 of 240. Sign in to see all of them.
Pain, Postoperative (66) · Agnosia (23) · Low Back Pain (14) · Acute Pain (13) · Chronic Pain (12) · Back Pain (8) · Headache (7) · Neuralgia (7) · Angina Pectoris (6) · Shoulder Pain (6) · Angina, Stable (5) · Angina, Unstable (5) · Opioid-Related Disorders (5) · Osteoarthritis (5)
Neurologic Manifestations (240) · Pathological Conditions, Signs and Symptoms (240) · Signs and Symptoms (240) · Pathologic Processes (83) · Postoperative Complications (72) · Nervous System Diseases (54) · Musculoskeletal Diseases (30) · Neurobehavioral Manifestations (26) · Perceptual Disorders (25) · Cardiovascular Diseases (19) · Neuromuscular Diseases (19) · Vascular Diseases (18) · Joint Diseases (17) · Heart Diseases (16)
Acetaminophen (24) · Bupivacaine (18) · Sodium Chloride (16) · Dexamethasone (15) · Fentanyl (14) · Morphine (14) · Ropivacaine (12) · Lidocaine (11) · Ketamine (10) · Pregabalin (10) · Gabapentin (9) · Hydromorphone (8) · Ibuprofen (8) · Oxycodone (8) · Saline Solution (6)
Pfizer (8) · University of California, San Diego (6) · Duke University (4) · Montefiore Medical Center (4) · Northwestern University (4) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (4) · University of Aarhus (4) · University of Wisconsin, Madison (4) · Wake Forest University Health Sciences (4) · Antonios Likourezos (3) · Boston Scientific Corporation (3) · Cedars-Sinai Medical Center (3) · Massachusetts General Hospital (3) · Pacira Pharmaceuticals, Inc (3) · Rutgers, The State University of New Jersey (3)
United States (146) · Canada (19) · Denmark (10) · Germany (9) · United Kingdom (9) · France (6) · Italy (6) · Netherlands (5) · South Korea (5) · Switzerland (5) · Spain (4) · Brazil (3) · Hungary (3) · Mexico (3) · Sweden (3)
Brian M Ilfeld, M.D., M.S. (2) · Edmund Volkerts, PhD (2) · Graeme A McLeod, MD FRCA (2) · Jack W Tsao, MD (2) · James C Eisenach, MD (2) · Ole Mathiesen, MD (2) · Roger K Cady, MD (2) · Roya Yumul, MD, PhD (2) · Aaron Fox, MD (1) · Ajay D Wasan, MD, MSc (1) · Albert Losken, MD (1) · Alireza Aminsharifi, M.D. (1) · Allan Struthers, BSc, MD, FRCP, FRSE, FMedSci (1)
PMID 1015603, PMID 11331167, PMID 11331334, PMID 11374619, PMID 11472277, PMID 12411815, PMID 12548273, PMID 12560416, PMID 14622770, PMID 16691088, PMID 17138203, PMID 17413915, PMID 18686750, PMID 18762870, PMID 19066382, PMID 19157368, PMID 19174373, PMID 19690943, PMID 20959867, PMID 22020082, PMID 22467891, PMID 22506940, PMID 23061994, PMID 23423135, PMID 23569691, PMID 23709323, PMID 23788067, PMID 23878064, PMID 25135035, PMID 25767411, PMID 2589650, PMID 26185466, PMID 26330019, PMID 26628263, PMID 26759680, PMID 27288381, PMID 27714758, PMID 27782769, PMID 27787895, PMID 28348503, PMID 32527192, PMID 33238043, PMID 37089721, PMID 41475826, PMID 9862240
2008 (4), 2016 (2), 2019 (2), R01NS057594 (2), 1RM1DA055437-01 (1), 2005 (1), 2017 (1), P01GM113852 (1), R01DA036564 (1)