1808 completed, 486 unknown, 225 recruiting, 130 terminated. 1928 Not applicable, 173 Phase 3, 142 Phase 2, 138 Phase 4, 78 Phase 1.
Follow Back Pain: new trials by email Literature Review of Back Pain trials Research Report on Back Pain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Preventing the Transition From Acute to Persistent Disabling Low Back Pain Through Cognitive Functional Therapy Cognitive Functional Therapy (CFT), Usual Care - Acute Low Back Pain (Low Back Pain for Less Than 3 Months) | Not applicable | Not yet recruiting | University of Oulu | 461 | 2027-09-01 | 2026-10-16 |
| Therapeutic Exercise and Education for Low Back Pain Therapeutic Exercise, Education on the self-management of low back pain, Usual Care - Low Back Pain | Not applicable | Not yet recruiting | University of Valladolid | 132 | 2027-03-01 | 2026-10-20 |
| Semaglutide for Low Back Pain Semaglutide (administered by PDS290 pen-injector), Placebo (administered by PDS290 pen-injector) - Lower Back Pain, Obesity (BMI>30) | Phase 2 | Not yet recruiting | Washington University School of Medicine | 250 | 2027-02-01 | 2026-07-28 |
| Randomized Evaluation of Lumbar Injection Effectiveness and Function Triojection® System, Selective Nerve Root Block (SNRB) - Lumbar Radiculopathy, Lumbar Disc Herniation | Not applicable | Not yet recruiting | SpinaFX Medical Inc. | 300 | 2027-01-15 | 2026-10-07 |
| A Comparison Between Ischial-Containment and Sub-Ischial Prosthetic Sockets to Determine Their Effects on Secondary Health Conditions Unilateral Transfemoral Amputation | Not yet recruiting | VA Office of Research and Development | 45 | 2027-01-01 | 2026-08-17 | |
| The Effect of Chiropractic Care on Opioid Use for Chronic Spinal Pain: A Feasibility Study Usual Medical Care, Usual Medical Care + Chiropractic Care - Back Pain | Not applicable | Not yet recruiting | McMaster University | 24 | 2026-12-01 | 2026-10-14 |
| Differences in Mechanistic Measures (Oxytocin and Cortisol) of Therapeutic Alliance Between A Talk-Based Therapy and Soft-Tissue Mobilization in Individuals With Chronic Spinal Pain Massage, Talk-based therapy - Spine, Low Back Pain | Not applicable | Not yet recruiting | Duke University | 25 | 2026-12-01 | 2026-10-16 |
| Effect of Dry Needling Plus Vibration on Myofascial Trigger Points in Individuals With Nonspecific Low Back Pain Dry Needling with Vibration + Exercise, Conventional Dry Needling + Exercise - Low Back Pain, Dry Needling | Not applicable | Not yet recruiting | Universidad de Zaragoza | 108 | 2026-12-01 | 2026-10-05 |
| Effect of Kinesio Taping Versus Myofascial Release on Menstrual Low Back Pain kinesio taping, myofascial release technique - Low Back Pain | Not applicable | Not yet recruiting | Cairo University | 44 | 2026-11-15 | 2026-04-02 |
| Magnetic Resonance Elastography Of Chronic Low Back Pain Before And After Therapy EMMA (Expert Manipulative Massage Automation) - Low Back Pain, Recurrent, Chronic Low Back Pain (CLBP) | Not applicable | Not yet recruiting | Mayo Clinic | 38 | 2026-11-01 | 2026-09-17 |
| Implementation of Evidence-based Guidelines for Assessment and Counseling of Patients With Neck and Back Pain in Health Care Centers Manual terapeut management - Backpain, Neck and Shoulder Pain | Not applicable | Not yet recruiting | Karolinska Institutet | 600 | 2026-11-01 | 2026-09-17 |
| Gamified Home-Based Core Neuromuscular Training for Chronic Low Back Pain Gamified Intervention Group: core neuromuscular exercise program using a digital application with gamification features, Non-Gamified Control Group - Low Back Pain, Low Back Pain and Core Muscle | Not applicable | Not yet recruiting | Princess Nourah Bint Abdulrahman University | 60 | 2026-11-01 | 2026-10-22 |
| The Effect of Core Stabilization Exercises on Balance in Older Adults With Low Back Pain Core stabilisation exercises + usual physiotherapy care, Usual physiotherapy care + general exercise programme - Chronic Non-Specific Low Back Pain | Not applicable | Not yet recruiting | University of West Attica | 60 | 2026-10-25 | 2026-09-29 |
| TECAR Therapy and Chronic Low Back Pain Control Group, TECAR therapy - TECAR Therapy, Low Back Pain | Not applicable | Not yet recruiting | Cairo University | 80 | 2026-10-20 | 2026-09-17 |
| TECAR Therapy in Chronic Back Pain TECAR Therapy plus Hi-EMS, Tecar therapy alone - Chronic Low-back Pain (cLBP), Non Specific Chronic Low Back Pain | Not applicable | Not yet recruiting | University of Hartford | 37 | 2026-10-19 | 2026-09-15 |
| The Ultrasound-Guided Dextrose Prolotherapy in Ehlers-Danlos Syndrome Patients Dextrose 50% Intravenous Solution, Lidocaine 1% Injectable Solution - Ehlers-Danlos Syndrome, Low Back Pain | Phase 3 | Withdrawn | Tulane University | 2026-10-05 | 2026-10-08 | |
| Pain Neuroscience Education and Neuromuscular Exercise in Individuals With Chronic Low Back Pain and Central Sensitization Pain Neuroscience Education, Neuromuscular Exercise - Low Back Pain, Chronic Low Back Pain | Not applicable | Not yet recruiting | Izmir Katip Celebi University | 66 | 2026-10-01 | 2026-10-15 |
| Impact of the Receptive Music Intervention Tool (MUSIC CARE©) on Changes in the Functional Abilities of Patients With Chronic Low Back Pain Receptive Music Therapy - Low Back Pain, Kinesiophobia (Fear of Movement) | Not applicable | Not yet recruiting | LNA SANTE | 34 | 2026-10-01 | 2026-07-28 |
| Virtual Tai Chi for Chronic Low Back Pain (Spine 2027) Virtually Delivered Integrated Tai Chi, Qigong, and Meditation (VDTQM) - Low Back Pain, Chronic Low-back Pain (cLBP) | Not applicable | Not yet recruiting | New York Medical College | 600 | 2026-10-01 | 2026-08-19 |
| Comparing Non-Medicine Strategies for Improving Low Back Pain ENCompaSS (Education, Navigated Care, and Supported Self-Management) with VA Stepped Usual Care - Chronic Low-back Pain (cLBP), High-Impact Chronic Pain (HICP) | Not applicable | Not yet recruiting | Duke University | 530 | 2026-10-01 | 2026-07-28 |
Showing 20 of 2951. Sign in to see all of them.
Low Back Pain (2356) · Chronic Pain (279) · Pain (253) · Motor Activity (151) · Neck Pain (147) · Failed Back Surgery Syndrome (104) · Intervertebral Disc Displacement (86) · Radiculopathy (79) · Intervertebral Disc Degeneration (76) · Sciatica (60) · Spinal Stenosis (55) · Musculoskeletal Pain (54) · Neuralgia (54) · Bronchiolitis Obliterans Syndrome (48)
Pathological Conditions, Signs and Symptoms (2951) · Neurologic Manifestations (2946) · Signs and Symptoms (2943) · Pain (2698) · Musculoskeletal Diseases (422) · Nervous System Diseases (325) · Bone Diseases (257) · Spinal Diseases (226) · Behavior (218) · Neuromuscular Diseases (217) · Pathologic Processes (205) · Peripheral Nervous System Diseases (189) · Postoperative Complications (118) · Joint Diseases (110)
Exercise (96) · Physical Therapy Modalities (59) · Musculoskeletal Manipulations (41) · Transcutaneous Electric Nerve Stimulation (40) · Exercise Therapy (38) · Control Groups (34) · Manipulation, Spinal (31) · Spinal Cord Stimulation (31) · Dry Needling (27) · Acupuncture Therapy (26) · Educational Status (24) · Acetaminophen (23) · Ibuprofen (23) · Cognitive Behavioral Therapy (20) · Manipulation, Osteopathic (20)
Riphah International University (114) · Cairo University (57) · Hacettepe University (26) · Foundation University Islamabad (25) · Boston Scientific Corporation (22) · University of Florida (21) · VA Office of Research and Development (21) · University of Utah (20) · Uskudar University (18) · Assistance Publique - Hôpitaux de Paris (17) · Istanbul Medipol University Hospital (17) · Kovacs Foundation (16) · Brigham and Women's Hospital (15) · Johns Hopkins University (14) · Assiut University (13)
United States (806) · Turkey (Türkiye) (285) · Pakistan (198) · Spain (174) · Brazil (116) · France (105) · Egypt (103) · Canada (101) · Belgium (89) · Denmark (65) · Germany (59) · Italy (59) · South Korea (53) · Switzerland (52) · United Kingdom (44)
Francisco M Kovacs, MD, PhD (14) · Laxmaiah Manchikanti, MD (9) · Steven P Cohen, MD (9) · Maarten Moens, Prof. dr. (6) · Muhammad Osama, PhD* (6) · Roshini Jain (6) · Andrew Finn, PharmD (5) · Mario Gestoso, MD (5) · Martin Descarreaux, DC, PhD (5) · Arnaud Dupeyron, MD, PhD (4) · Kevin Farrell (4)
PMID 34854473, PMID 27745712, PMID 11074683, PMID 11172169, PMID 22048651, PMID 31631992, PMID 10470716, PMID 10872758, PMID 11124727, PMID 11175676, PMID 11733293, PMID 15129077, PMID 15207508, PMID 16550448, PMID 18165754, PMID 18648237, PMID 19470987, PMID 20567613, PMID 21120303, PMID 21256073, PMID 21982256, PMID 22231424, PMID 22236541, PMID 22304678, PMID 23340531, PMID 24650448, PMID 24985410, PMID 25380224, PMID 25932092, PMID 26501533, PMID 26554876, PMID 26814279, PMID 27825292, PMID 28192789, PMID 29480409, PMID 29509867, PMID 29573870, PMID 30217693, PMID 31960773, PMID 32056864, PMID 32411374, PMID 33541362, PMID 34052655, PMID 35346331, PMID 35507483, PMID 36045306, PMID 36484691, PMID 36775506, PMID 37395948, PMID 39198005
2023 (6), 2019 (5), 2009 (3), 2016 (3), U01AR045444 (3), 2015 (2), 2017 (2), 2018 (2), 4UH3AR076731-02 (2), K01HD053632 (2), K12NS130673 (2), R01AT006334 (2), R01MD018937 (2), R44DA049631 (2), R44NS125745 (2)