1818 completed, 485 unknown, 223 recruiting, 133 not yet recruiting. 1944 Not applicable, 173 Phase 3, 142 Phase 2, 138 Phase 4, 78 Phase 1.
Follow Back Pain: new trials by email Literature Review of Back Pain trials Research Report on Back Pain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Preventing the Transition From Acute to Persistent Disabling Low Back Pain Through Cognitive Functional Therapy Cognitive Functional Therapy (CFT), Usual Care - Acute Low Back Pain (Low Back Pain for Less Than 3 Months) | Not applicable | Not yet recruiting | University of Oulu | 461 | 2027-09-01 | 2026-10-16 |
| Therapeutic Exercise and Education for Low Back Pain Therapeutic Exercise, Education on the self-management of low back pain, Usual Care - Low Back Pain | Not applicable | Not yet recruiting | University of Valladolid | 132 | 2027-03-01 | 2026-10-20 |
| Semaglutide for Low Back Pain Semaglutide (administered by PDS290 pen-injector), Placebo (administered by PDS290 pen-injector) - Lower Back Pain, Obesity (BMI>30) | Phase 2 | Not yet recruiting | Washington University School of Medicine | 250 | 2027-02-01 | 2026-07-28 |
| Evaluation of a Program to Prevent Recurrences of Episodes of Acute Low Back Pain, Assisted by the Axomove Application 2 exercises program supervised by a physical therapist via a digital application, Care as usual - Low Back Pain | Not applicable | Not yet recruiting | University Hospital, Bordeaux | 194 | 2027-01-31 | 2026-11-04 |
| Randomized Evaluation of Lumbar Injection Effectiveness and Function Triojection® System, Selective Nerve Root Block (SNRB) - Lumbar Radiculopathy, Lumbar Disc Herniation | Not applicable | Not yet recruiting | SpinaFX Medical Inc. | 300 | 2027-01-15 | 2026-10-07 |
| A Comparison Between Ischial-Containment and Sub-Ischial Prosthetic Sockets to Determine Their Effects on Secondary Health Conditions Unilateral Transfemoral Amputation | Not yet recruiting | VA Office of Research and Development | 45 | 2027-01-01 | 2026-08-17 | |
| Spinery Basivertebral Nerve Ablation for Vertebrogenic Chronic Low Back Pain Single Bipolar Ablation, Double Parallel Bipolar Ablation, Double Cross Bipolar Ablation - Low Back Pain, Chronic Low Back Pain (CLBP) | Not applicable | Not yet recruiting | Axon srl | 69 | 2027-01-01 | 2026-11-06 |
| Neuromuscular Taping on Muscle Pain in Patients With Degenerative Osteoarticular Disease of the Spine kinesio taping, sham kinesiotaping - Cervicalgia, Back Pain, Low | Not applicable | Not yet recruiting | Consorci Sanitari de l'Alt Penedès i Garraf | 500 | 2027-01-01 | 2026-11-09 |
| The Effect of Chiropractic Care on Opioid Use for Chronic Spinal Pain: A Feasibility Study Usual Medical Care, Usual Medical Care + Chiropractic Care - Back Pain | Not applicable | Not yet recruiting | McMaster University | 24 | 2026-12-01 | 2026-10-14 |
| Differences in Mechanistic Measures (Oxytocin and Cortisol) of Therapeutic Alliance Between A Talk-Based Therapy and Soft-Tissue Mobilization in Individuals With Chronic Spinal Pain Massage, Talk-based therapy - Spine, Low Back Pain | Not applicable | Not yet recruiting | Duke University | 25 | 2026-12-01 | 2026-10-16 |
| Effect of Dry Needling Plus Vibration on Myofascial Trigger Points in Individuals With Nonspecific Low Back Pain Dry Needling with Vibration + Exercise, Conventional Dry Needling + Exercise - Low Back Pain, Dry Needling | Not applicable | Not yet recruiting | Universidad de Zaragoza | 108 | 2026-12-01 | 2026-10-05 |
| Pilot Study: Clinical Trial of Ultrasound Guiding Pharmacopuncture Therapy for Acute Low Back Pain Ultrasound-guided Deep Pharmacopuncture Treatment, Korean medical treatment - Low Back Pain (LBP) | Not applicable | Not yet recruiting | Jaseng Medical Foundation | 40 | 2026-12-01 | 2026-11-05 |
| Comparing Non-Medicine Strategies for Improving Low Back Pain ENCompaSS (Education, Navigated Care, and Supported Self-Management) with VA Stepped Usual Care - Chronic Low-back Pain (cLBP), High-Impact Chronic Pain (HICP) | Not applicable | Not yet recruiting | Duke University | 530 | 2026-12-01 | 2026-11-06 |
| Analysis of Crepitus in Human Subjects Range of motion with spinal adjustment - Low Back Pain, Healthy | Not yet recruiting | National University of Health Sciences | 12 | 2026-12-01 | 2026-11-10 | |
| Brain Connectivity and Perceptive Surfaces in Chronic Low Back Pain (SUPER-RMNf) Perceptive Surface (SU-PER mat) - Low Back Pain, Healthy | Not applicable | Not yet recruiting | G. d'Annunzio University | 40 | 2026-12-01 | 2026-11-09 |
| Effect of Kinesio Taping Versus Myofascial Release on Menstrual Low Back Pain kinesio taping, myofascial release technique - Low Back Pain | Not applicable | Not yet recruiting | Cairo University | 44 | 2026-11-15 | 2026-04-02 |
| The Influence of Hydration on the Viscoelastic Properties of Soft Tissues, Pain and Mobility of Patients hydration, Stecco's Fascial Manipulation therapy, Stecco Fascial Manipulation Therapy + Hydration - Low Back Pain (LBP), Fascial Manipulation | Not applicable | Enrolling by invitation | The Jerzy Kukuczka Academy of Physical Education in Katowice | 80 | 2026-11-15 | 2026-11-04 |
| Study Designed to Assess the Efficacy and Safety of the Neurolyser XR After Marketing Approval High Intensity Focused Ultrasound - Lumbar Zygapophyseal Pain, Low Back Pain | Not yet recruiting | FUSMobile Inc. | 60 | 2026-11-12 | 2026-11-09 | |
| Magnetic Resonance Elastography Of Chronic Low Back Pain Before And After Therapy EMMA (Expert Manipulative Massage Automation) - Low Back Pain, Recurrent, Chronic Low Back Pain (CLBP) | Not applicable | Not yet recruiting | Mayo Clinic | 38 | 2026-11-01 | 2026-09-17 |
| Implementation of Evidence-based Guidelines for Assessment and Counseling of Patients With Neck and Back Pain in Health Care Centers Manual terapeut management - Backpain, Neck and Shoulder Pain | Not applicable | Not yet recruiting | Karolinska Institutet | 600 | 2026-11-01 | 2026-09-17 |
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Low Back Pain (2372) · Chronic Pain (279) · Pain (253) · Motor Activity (152) · Neck Pain (148) · Failed Back Surgery Syndrome (104) · Intervertebral Disc Displacement (87) · Radiculopathy (81) · Intervertebral Disc Degeneration (76) · Sciatica (60) · Musculoskeletal Pain (55) · Spinal Stenosis (55) · Neuralgia (54) · Bronchiolitis Obliterans Syndrome (48)
Pathological Conditions, Signs and Symptoms (2968) · Neurologic Manifestations (2963) · Signs and Symptoms (2960) · Pain (2715) · Musculoskeletal Diseases (424) · Nervous System Diseases (327) · Bone Diseases (258) · Spinal Diseases (227) · Behavior (219) · Neuromuscular Diseases (219) · Pathologic Processes (205) · Peripheral Nervous System Diseases (191) · Postoperative Complications (118) · Joint Diseases (111)
Exercise (96) · Physical Therapy Modalities (59) · Musculoskeletal Manipulations (41) · Transcutaneous Electric Nerve Stimulation (40) · Exercise Therapy (38) · Control Groups (34) · Manipulation, Spinal (32) · Spinal Cord Stimulation (31) · Dry Needling (27) · Acupuncture Therapy (26) · Educational Status (24) · Acetaminophen (23) · Ibuprofen (23) · Cognitive Behavioral Therapy (20) · Manipulation, Osteopathic (20)
Riphah International University (115) · Cairo University (58) · Hacettepe University (26) · Foundation University Islamabad (25) · Boston Scientific Corporation (22) · University of Florida (21) · VA Office of Research and Development (21) · University of Utah (20) · Uskudar University (18) · Assistance Publique - Hôpitaux de Paris (17) · Istanbul Medipol University Hospital (17) · Kovacs Foundation (16) · Brigham and Women's Hospital (15) · Johns Hopkins University (14) · Assiut University (13)
United States (806) · Turkey (Türkiye) (287) · Pakistan (205) · Spain (176) · Brazil (116) · France (105) · Egypt (104) · Canada (101) · Belgium (89) · Denmark (65) · Germany (59) · Italy (59) · South Korea (53) · Switzerland (52) · United Kingdom (44)
Francisco M Kovacs, MD, PhD (14) · Laxmaiah Manchikanti, MD (9) · Steven P Cohen, MD (9) · Maarten Moens, Prof. dr. (6) · Muhammad Osama, PhD* (6) · Roshini Jain (6) · Andrew Finn, PharmD (5) · Mario Gestoso, MD (5) · Martin Descarreaux, DC, PhD (5) · Arnaud Dupeyron, MD, PhD (4) · Kevin Farrell (4)
PMID 34854473, PMID 27745712, PMID 10872758, PMID 11074683, PMID 11172169, PMID 22048651, PMID 31631992, PMID 10470716, PMID 11124727, PMID 11175676, PMID 11733293, PMID 15129077, PMID 15207508, PMID 16550448, PMID 18165754, PMID 18648237, PMID 19470987, PMID 20567613, PMID 21120303, PMID 21256073, PMID 21982256, PMID 22231424, PMID 22236541, PMID 22304678, PMID 23340531, PMID 24650448, PMID 24985410, PMID 25380224, PMID 25932092, PMID 26501533, PMID 26554876, PMID 26814279, PMID 27825292, PMID 28192789, PMID 29480409, PMID 29509867, PMID 29573870, PMID 30217693, PMID 31960773, PMID 32056864, PMID 32411374, PMID 32669487, PMID 33541362, PMID 34052655, PMID 35346331, PMID 35507483, PMID 36045306, PMID 36484691, PMID 36775506, PMID 37395948
2023 (6), 2019 (5), 2009 (3), 2016 (3), U01AR045444 (3), 2015 (2), 2017 (2), 2018 (2), 4UH3AR076731-02 (2), K01HD053632 (2), K12NS130673 (2), R01AT006334 (2), R01MD018937 (2), R44DA049631 (2), R44NS125745 (2)