1095 completed, 204 recruiting, 174 terminated, 119 withdrawn. 892 Not applicable, 293 Phase 2, 131 Phase 1, 110 Phase 4, 77 Phase 3.
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Preoperative Durvalumab, Cisplatin, Gemcitabine With or Without Futibatinib Targeted Therapy for the Treatment of Resectable Intrahepatic Cholangiocarcinoma, OPTIC Trial Biospecimen Collection, Cisplatin, Computed Tomography - Resectable Intrahepatic Cholangiocarcinoma | Phase 2 | Not yet recruiting | Northwestern University | 44 | 2027-12-10 | 2026-06-10 |
| Futibatinib With Paclitaxel and Ramucirumab for the Treatment of Locally Advanced or Unresectable Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Biospecimen Collection, Computed Tomography, Futibatinib - Clinical Stage II Esophageal Adenocarcinoma AJCC v8, Clinical Stage III Esophageal Adenocarcinoma AJCC v8 | Phase 1 | Not yet recruiting | Northwestern University | 18 | 2027-09-09 | 2026-10-20 |
| Epidermal Growth Factor Receptor Inhibition for Keratinopathies Erlotinib - Epidermolytic Ichthyosis, Palmoplantar Keratoderma | Phase 1 / Phase 2 | Not yet recruiting | Northwestern University | 44 | 2027-07-01 | 2026-08-03 |
| Enfortumab Vedotin for the Treatment of Unresectable or Metastatic Radioiodine Refractory Differentiated Thyroid Cancer, Anaplastic Thyroid Cancer, Medullary Thyroid Cancer, or NUT Carcinoma Biopsy Procedure, Biospecimen Collection, Computed Tomography - Metastatic Differentiated Thyroid Gland Carcinoma, Metastatic NUT Carcinoma | Phase 2 | Not yet recruiting | Northwestern University | 56 | 2027-05-05 | 2026-10-07 |
| Valproic AcId for Traumatic BRAin INjury Trial Valproic Acid (VPA), Standard of care treatment + normal saline - Moderate Traumatic Brain Injury (TBI), Severe Traumatic Brain Injury | Phase 2 / Phase 3 | Not yet recruiting | Northwestern University | 432 | 2027-05-01 | 2026-08-13 |
| REmote Physical ACtivity Intervention for High Blood Pressure Postpartum Patient Portal Messaging, FitBit EHR Linkage - Hypertension (HTN), Hypertension ,Pregnancy | Not applicable | Not yet recruiting | Northwestern University | 60 | 2027-04-01 | 2026-09-17 |
| SMAD4 Tailored Neoadjuvant Therapy for the Treatment of Resectable and Borderline Resectable Pancreatic Ductal Adenocarcinoma, SMART-PANC Trial Biospecimen Collection, Computed Tomography, Electronic Health Record Review - Borderline Resectable Pancreatic Ductal Adenocarcinoma, Resectable Pancreatic Ductal Adenocarcinoma | Phase 2 | Not yet recruiting | Northwestern University | 125 | 2027-02-03 | 2026-08-06 |
| Fit2ThriveMB: Optimization of a Physical Activity Promotion Intervention for Metastatic Breast Cancer Patients Core Intervention, EHR Integration (On v. Off), Weekly Coaching - Metastatic Breast Cancer, Metastatic Breast Cancer (MBC) | Not applicable | Not yet recruiting | Northwestern University | 224 | 2027-01-01 | 2026-10-01 |
| Use of a Vibration Tool for Postoperative Pain Control in Distal Radius Fractures Vibration tool - Distal Radius Fracture, Radius Fracture Distal | Not applicable | Not yet recruiting | Northwestern University | 100 | 2027-01-01 | 2026-07-10 |
| Scaling Out S.A.F.E. Firearm Across Two Health Systems as a Universal Suicide Prevention Strategy (SCALE ASPIRE) Implementation package (training, facilitation, electronic health record nudge) - Suicide | Not applicable | Not yet recruiting | Northwestern University | 5442 | 2027-01-01 | 2026-09-18 |
| Characterization of the Microbiome in Cutaneous T Cell Lymphoma Skin Lesions Before and After Use of APR-TD011® (RLF-TD011®) Spray Solution APR-TD011 (RLF-TD011) - Cutaneous T Cell Lymphoma | Early Phase 1 | Not yet recruiting | Northwestern University | 30 | 2027-01-01 | 2026-05-01 |
| Patient-Reported Outcomes Dashboard With Goal Setting to Support Shared Decision-Making in Inflammatory Arthritis Patient-Reported Outcomes Dashboard With Goal Setting - Arthritis, Psoriatic (PsA), Arthritis, Rheumatoid (RA) | Not applicable | Not yet recruiting | Northwestern University | 160 | 2027-01-01 | 2026-10-15 |
| The NICE-PAD II Trial Nicotinamide Riboside (NR), Placebo - Peripheral Artery Disease (PAD) | Phase 3 | Not yet recruiting | Northwestern University | 250 | 2026-12-01 | 2026-08-24 |
| PREcision MEDicine In Achalasia (PREMEDIA) - Cohort Type III Achalasia, EGJ Outflow Obstruction With Spastic/Hypercontractile Features | Recruiting | Northwestern University | 200 | 2026-12-01 | 2026-10-13 | |
| Personalized Prosthetic Foot Prescription and Rehabilitation for Veterans With Lower Limb Loss Prosthetic foot, Physical therapy - Amputation of Lower Limb | Not applicable | Not yet recruiting | Northwestern University | 50 | 2026-12-01 | 2026-06-10 |
| Hospital Based Continuous Patient Monitoring System Consumer Wearable Device Vital Sign Measurement - Trauma, Appendectomy | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 250 | 2026-11-01 | 2026-10-08 |
| Negotiation Training for Family Caregivers of People With Alzheimer's Disease NegotiAge, PlanYourLifespan - Alzheimer's Disease (AD), Dementia | Not applicable | Not yet recruiting | Northwestern University | 200 | 2026-11-01 | 2026-10-05 |
| The AYA Oncology Self-care Movement Educational Website, #AYAOSM - Acute Lymphobkastic Leukemia, Medication Adherence | Not applicable | Not yet recruiting | Northwestern University | 200 | 2026-11-01 | 2026-07-24 |
| Effects of Axatilimab on Skin in Chronic Graft-versus-Host Disease Axatilimab - Chronic Graft vs. Host Disease, GVHD | Not yet recruiting | Northwestern University | 15 | 2026-11-01 | 2026-09-22 | |
| ALDH2 Genetic Testing in East Asian Community Genetic Test Results Return, Alcohol Flushing Education - Healthy Adult, Flushing | Not applicable | Not yet recruiting | Northwestern University | 100 | 2026-11-01 | 2026-08-11 |
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PMID 42035974, PMID 36588397, PMID 20083690, PMID 24418949, PMID 27542666, PMID 27788130, PMID 28052888, PMID 31333167, PMID 32184035, PMID 32390569, PMID 32416309, PMID 32604132, PMID 32632956, PMID 33546709, PMID 33974019, PMID 34011176, PMID 34075780, PMID 34643538, PMID 36472416, PMID 36533626, PMID 37314323, PMID 37351709, PMID 38345934, PMID 38375882, PMID 40243391, PMID 41944009, PMID 42814673, PMID 10677100, PMID 10727592, PMID 10809840, PMID 10899243, PMID 10922023, PMID 11015796, PMID 11114834, PMID 11171742, PMID 11413123, PMID 11434936, PMID 11586297, PMID 11594853, PMID 11915838, PMID 11961474, PMID 11984258, PMID 11991872, PMID 12029810, PMID 12069640, PMID 12418071, PMID 12719282, PMID 12789165, PMID 12848636, PMID 12917318
P30CA060553 (104), P01HS021141 (4), P20MH090318 (4), UG1CA242643 (4), P50MH119029 (3), U01DK097772 (3), U01DK097779 (3), U01DK097780 (3), U01DK099879 (3), U01DK099932 (3), U01DK100011 (3), U01DK100017 (3), K08MH112878 (2), P50CA221747 (2), R01CA262357 (2)