40305 completed, 13321 unknown, 8743 recruiting, 4930 terminated. 26431 Not applicable, 11366 Phase 2, 6838 Phase 1, 6766 Phase 3, 6103 Phase 4.
Follow this condition Literature Review of Pathologic Processes trials Research Report on Pathologic Processes
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| 9-ING-41 Plus Carboplatin in Patients With Advanced, Metastatic Salivary Gland Carcinoma 9-ING-41, Carboplatin - Salivary Gland Carcinoma, Adenoid Cystic Carcinoma | Phase 2 | Withdrawn | Actuate Therapeutics Inc. | 2030-12-18 | 2022-02-22 | |
| Tau Pathology in the Brain After Hip or Knee Replacement Surgery Hip or Knee Arthroplasty Under Spinal Anesthesia - Postoperative Cognitive Dysfunction, Alzheimer Disease | Recruiting | Uppsala University Hospital | 30 | 2029-04-01 | 2026-10-15 | |
| PROstate Cancer Risk Calculator for ACTionable Clinical Decision-making in Nigeria (a) Training and (b) Supported risk assessment - Prostate Cancer, Risk Assessment | Not applicable | Not yet recruiting | Ahmadu Bello University | 89 | 2029-03-01 | 2026-07-29 |
| FGF-1 for Intramuscular Injection for the Treatment of Peripheral Arterial Disease FGF-1, Placebo - Peripheral Arterial Disease, Stenosis | Phase 1 / Phase 2 | Not yet recruiting | Venturis Therapeutics, Inc. | 24 | 2028-10-15 | 2026-08-19 |
| The Effect of Sympathetic Modulation on Cerebral Vasospasm Secondary to Aneurysmal Subarachnoid Hemorrhage Vectris trial leads and stimulation, Sham - Vasospasm, Cerebral, Aneurysmal Subarachnoid Hemorrhage | Not applicable | Suspended | University of Alabama at Birmingham | 25 | 2028-07-31 | 2026-09-24 |
| Postoperative Analgesia Using Ganglion Impar Block After Anal Surgery Ganglion impar block with Bupivacaine., Ganglion impar block with normal saline - Postoperative Pain | Not applicable | Not yet recruiting | University of Alexandria | 60 | 2028-07-01 | 2025-04-03 |
| MRI Technical Development and Applications in Kidney Disease Chronic Kidney Diseases, Kidney Transplantation | Not yet recruiting | University of Minnesota | 180 | 2028-06-30 | 2026-04-13 | |
| Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in Veterans Integrated care - Opioid Use Disorder, HIV | Not applicable | Not yet recruiting | VA Office of Research and Development | 60 | 2028-04-03 | 2026-04-24 |
| Validation of the iCVS Model in Patients Admitted to the Intensive Care Unit Shock | Not yet recruiting | Meir Medical Center | 1150 | 2028-04-01 | 2026-10-09 | |
| A Phase 1/2 Study of Personalized PSMA Radiopharmaceutical Therapy 177Lu-PSMA-I&T - escalating renal absorbed dose, 177Lu-PSMA-I&T - recommended phase 2 regime - Cancer, Prostate Cancer | Phase 1 / Phase 2 | Not yet recruiting | CHU de Quebec-Universite Laval | 500 | 2028-03-01 | 2025-03-30 |
| Effect of Ginger on Heavy Menstrual Bleeding in Women With Coagulation Disorders Ginger, Placebo - Women With Coagulation Disorders | Early Phase 1 | Not yet recruiting | University of Valladolid | 74 | 2028-02-01 | 2026-05-19 |
| Safety and Outcomes of MUSE Stem Cell Therapy in Individuals With Traumatic Brain Injury MUSE Stem Cell Therapy - Traumatic Brain Injury, Traumatic Brain Injury (TBI) Patients | Not yet recruiting | Healing Hope International | 10 | 2028-01-01 | 2026-03-10 | |
| Standalone Thoracoscopic Left Atrial Appendage Closure Versus Medical Therapy in Atrial Fibrillation Video-assisted thoracoscopic closure of the left atrial appendage using a closure device and discontinuation of treatment if the patient is treated with OAC - ATRIAL APPENDAGE CLOSURE for ATRIAL FIBRILLATION, Oral Anticoagulation | Not applicable | Not yet recruiting | Region Skane | 936 | 2028-01-01 | 2026-07-15 |
| OPTIMAL LEAP: Optimizing Dihydroartemisinin-Piperaquine IPTsc Intervals to Advance Learning, Executive Function, Attendance, and Antimalarial Resistance Surveillance in Kenyan Schoolchildren Monthly DP, Quarterly DP - Malaria, Asymptomatic Malaria | Phase 3 | Not yet recruiting | Indiana University | 1500 | 2028-01-01 | 2026-09-01 |
| Screening Cardiometabolic Opportunities Using Transformative Echocardiography Artificial Intelligence (SCOUT Echo-AI) AI-Enabled Identification (EchoNet-Liver) - MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Cirrhosis | Not applicable | Not yet recruiting | Kaiser Permanente | 2000 | 2028-01-01 | 2026-08-13 |
| Effectiveness of Laser Visual Feedback in Postural Control After a Stroke Intervention - Ictus, Convalescence | Not applicable | Not yet recruiting | Parc Sanitari Pere Virgili | 60 | 2028-01-01 | 2026-09-10 |
| Perioperative Esketamine Safety and Efficacy in Reducing Postoperative ENDometriosis PAIN (the ENDPAIN Trial): a Randomized Controlled Trial. Esketamine, Placebo - Endometriosis | Phase 4 | Not yet recruiting | Region Skane | 1000 | 2028-01-01 | 2026-10-19 |
| Psilocybin After Trauma Surgery for Pain Psilocybin (Usona Institute), Postoperative analgesia - Pain Management, Postoperative Pain | Phase 1 | Not yet recruiting | Trent Emerick | 70 | 2027-12-31 | 2026-08-06 |
| AI-assisted Subtyping-directed Precision Treatment in Acute Aortic Dissection Ulinastatin and Thymalfasin, Ulinastatin - Aortic Aneurysm and Dissection | Not applicable | Not yet recruiting | Nanjing Medical University | 300 | 2027-12-31 | 2026-02-02 |
| Study to Evaluate the effIcacy and Safety of Abelacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral Anticoagulation Abelacimab - Atrial Fibrillation (AF) | Phase 3 | Not yet recruiting | Novartis Pharmaceuticals | 2500 | 2027-12-30 | 2026-07-31 |
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Pain, Postoperative (5409) · Pulmonary Disease, Chronic Obstructive (5326) · Atrial Fibrillation (3820) · Neoplasm Metastasis (3584) · Inflammation (3524) · Recurrence (3506) · Renal Insufficiency, Chronic (3069) · Disease (2395) · Sepsis (2287) · Leukemia, Lymphocytic, Chronic, B-Cell (2018) · Kidney Failure, Chronic (1996) · Myocardial Infarction (1960) · Critical Illness (1759) · Neoplasms (1646) · Hemorrhage (1381)
Pathological Conditions, Signs and Symptoms (77097) · Disease Attributes (29251) · Chronic Disease (17979) · Cardiovascular Diseases (15511) · Signs and Symptoms (14233) · Neoplasms (12051) · Infections (11797) · Respiratory Tract Diseases (11347) · Urogenital Diseases (10868) · Heart Diseases (10204) · Vascular Diseases (10091) · Neurologic Manifestations (10061) · Lung Diseases (9504) · Nervous System Diseases (9328)
Saline Solution (773) · Sodium Chloride (769) · Cyclophosphamide (686) · Dexamethasone (616) · Blood Specimen Collection (596) · Standard of Care (540) · Rituximab (513) · Bupivacaine (511) · Exercise (480) · Ribavirin (438) · Dexmedetomidine (367) · fludarabine phosphate (365) · fludarabine (345) · Tranexamic Acid (338) · Acetaminophen (318)
Assiut University (673) · Assistance Publique - Hôpitaux de Paris (584) · GlaxoSmithKline (545) · Novartis Pharmaceuticals (491) · AstraZeneca (485) · M.D. Anderson Cancer Center (462) · National Cancer Institute (NCI) (453) · Cairo University (432) · Mayo Clinic (386) · Boehringer Ingelheim (362) · National Taiwan University Hospital (328) · Ain Shams University (311) · Massachusetts General Hospital (308) · Merck Sharp & Dohme LLC (266) · University of California, San Francisco (265)
United States (22419) · China (6838) · France (6134) · Canada (4553) · Germany (4438) · United Kingdom (4178) · Italy (3997) · Spain (3911) · Turkey (Türkiye) (3657) · Netherlands (2505) · South Korea (2333) · Belgium (2267) · Denmark (2163) · Egypt (2105) · Australia (1842)
PMID 40576086, PMID 36005278, PMID 41276263, PMID 33511633, PMID 34515338, PMID 35224730, PMID 35018639, PMID 36791280, PMID 26903338, PMID 37870112, PMID 32499241, PMID 37916745, PMID 37870148, PMID 41114449, PMID 30739368, PMID 34932836, PMID 38189593, PMID 33232518, PMID 33586138, PMID 34495549, PMID 32390133, PMID 32609374, PMID 32943047, PMID 36700520, PMID 30977945, PMID 32860505, PMID 34164803, PMID 34398557, PMID 34519356, PMID 35815359, PMID 37467180, PMID 42149813, PMID 27501016, PMID 30012435, PMID 30923816, PMID 33283264, PMID 34022170, PMID 34473343, PMID 36416787, PMID 36472416, PMID 37542951, PMID 37651553, PMID 41159585, PMID 11253156, PMID 30957581, PMID 31568620, PMID 32588430, PMID 33782940, PMID 36748942, PMID 38018702
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