526 completed, 77 recruiting, 76 terminated, 45 active not recruiting. 395 Not applicable, 68 Phase 3, 63 Phase 4, 46 Phase 2, 18 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Impact of Endoscopic Sleeve Gastroplasty (ESG) in Obese Adults With Type 2 Diabetes (T2D) ESG with OverStitch - Type 2 Diabetes Mellitus (T2D), Obesity (BMI>30) | Not applicable | Not yet recruiting | Boston Scientific Corporation | 50 | 2027-04-01 | 2026-09-24 |
| A Post Approval Study to Evaluate Safety and Effectiveness of Multicompartmental Dosimetry Planning. TheraSphere - Hepatocellular Carcinoma (HCC) | Not yet recruiting | Boston Scientific Corporation | 140 | 2027-01-01 | 2026-10-01 | |
| Augmented Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for PE Ultrasound-facilitated, catheter-directed lower-dose fibrinolysis, Tissue Plasminogen Activator - Pulmonary Embolism, Right Ventricular Dysfunction | Suspended | Brigham and Women's Hospital | 60 | 2027-01-01 | 2026-01-21 | |
| Study of Eso-SPONGE for Treating Leaks After Upper Gastrointestinal Surgery sponge-based Endoscopic Vacuum Therapy (EVT) using Eso-SPONGE - Anastomotic Leaks | Not applicable | Not yet recruiting | Boston Scientific Corporation | 74 | 2026-12-01 | 2026-10-19 |
| A Prospective, Multicenter, Single Arm Registry of ENROUTE NPS in Conjunction With Carotid WALLSTENT in Chinese Population transcarotid artery revascularization - Carotid Artery Stenosis | Not yet recruiting | Boston Scientific Corporation | 60 | 2026-11-30 | 2026-09-25 | |
| Cholinergic Deep Brain Stimulation for Alzheimer's Disease Device Implantation- Boston Scientific, VERCISE GENUS™ system, DBS Stimulation - Boston Scientific, VERCISE GENUS™ system - Alzheimer Disease, Early Onset, Dementia | Not applicable | Enrolling by invitation | Vanderbilt University Medical Center | 2 | 2026-11-01 | 2026-09-01 |
| A Global Randomized Trial Evaluating the FARAFLEX™ Mapping and Pulsed Field Ablation System With Electrographic Flow Mapping in Patients Undergoing Repeat Ablation for Atrial Fibrillation FARAFLEX Mapping and Pulsed Field Ablation System - Atrial Fibrillation (AF), Persistent Atrial Fibrillation (PersAF) | Not applicable | Not yet recruiting | Boston Scientific Corporation | 650 | 2026-11-01 | 2026-09-28 |
| Drug-Coated Balloon Only Strategy After Recanalization of Chronic Total Coronary Occlusions Paclitaxel-coated balloon (AGENT Paclitaxel-Coated PTCA Balloon Catheter), Serial intravascular ultrasound and protocol-mandated nine-month angiographic reassessment - Angina (Stable), Coronary Occlusion | Not applicable | Not yet recruiting | University of Sao Paulo General Hospital | 38 | 2026-11-01 | 2026-09-14 |
| Endo-SPONGE for Treatment of Anastomotic or Hartmann's Stump Leakages in Lower Pelvic Area Endo-SPONGE - Anastomotic Leaks, Hartmanns Stump Leakage | Not applicable | Recruiting | Boston Scientific Corporation | 66 | 2026-11-01 | 2026-10-19 |
| Combined CM and STN Stimulation for Motor Epilepsy Deep brain stimulation - Motor Epilepsy | Not applicable | Not yet recruiting | Boston Scientific Corporation | 10 | 2026-10-31 | 2026-09-25 |
| Monitoring for CardioToxicity Using WeArable deVices While Undergoing cancEr Treatments (MCT-WAVE) Mobile Cardiac Telemetry, Wearable Cardiac Monitor - Cardiotoxicity, Cancer | Not applicable | Not yet recruiting | University of Minnesota | 72 | 2026-10-29 | 2026-10-06 |
| CASTLE-HFpEF (Catheter Ablation for Atrial Fibrillation Patients With Heart Failure With Mildly Reduced and Preserved Ejection Fraction) Catheter ablation - Atrial Fibrillation, Heart Failure With Preserved Ejection Fraction | Not applicable | Not yet recruiting | Tulane University | 900 | 2026-10-01 | 2026-10-01 |
| Routine Microaxial Heart Pump Support and Protocolized Pulmonary Artery Catheter Monitoring Versus Standard Care in Heart Attack-Related Cardiogenic Shock Microaxial flow pump (left ventricular assist device), Pulmonary artery catheter, Conventional hemodynamic monitoring - Cardiogenic Shock, Acute Myocardial Infarction (AMI) | Not applicable | Not yet recruiting | Leipzig Heart Science gGmbH | 780 | 2026-10-01 | 2026-08-24 |
| An Optimization Study Evaluating Safety and Efficacy of the Y-90 Glioblastoma (GBM) Device in Patients With Recurrent GBM Device: TheraSphere GBM treatment of TheraSphere GBM device - Recurrent Glioblastoma | Not applicable | Not yet recruiting | Boston Scientific Corporation | 30 | 2026-10-01 | 2026-10-09 |
| Elite AF IDE Trial (Elite AF) WATCHMAN Elite LAAC Device - Atrial Fibrillation (AF), Stroke | Not applicable | Recruiting | Boston Scientific Corporation | 400 | 2026-09-18 | 2026-10-16 |
| A Real-World Study of EkoSonic Endovascular System in Chinese Populations With Acute Pulmonary Embolism EkoSonicTM Endovascular System - Acute Pulmonary Embolism | Recruiting | Boston Scientific Corporation | 30 | 2026-08-30 | 2026-09-29 | |
| Real-World Treatment of Extracranial Carotid Artery Disease With the ENROUTE™ Transcarotid Neuroprotection System Use of ENROUTE™ Transcarotid Neuroprotection System in conjunction with any commercially available Boston Scientific stent marketed for treatment of carotid artery disease - Extracranial Carotid Artery Disease, TCAR | Recruiting | Boston Scientific Corporation | 5000 | 2026-08-19 | 2026-10-21 | |
| BOdygUardian MOnitoriNg for ReCurrencE of AF BodyGuardian - Atrial Fibrillation (AF) | Recruiting | Heart Rhythm Clinical and Research Solutions, LLC | 100 | 2026-08-13 | 2026-10-20 | |
| Fainting Detection And Early Warning In Syncope Evaluation Study (ARISE) Wearable holter monitor - Orthostatic Hypotension, Reflex Syncope | Recruiting | Boston Scientific Corporation | 40 | 2026-08-06 | 2026-10-14 | |
| OverStitch NXT Endoscopic Suture System OverStitch NXT Endoscopic Suture System - Weight Loss | Not applicable | Recruiting | Boston Scientific Corporation | 136 | 2026-08-06 | 2026-09-25 |
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Atrial Fibrillation (101) · Coronary Artery Disease (82) · Heart Failure (74) · Chronic Pain (37) · Arrhythmias, Cardiac (23) · Tachycardia, Ventricular (23) · Aortic Valve Stenosis (22) · Atherosclerosis (21) · Pain (21) · Cardiovascular Diseases (20) · Parkinson Disease (20) · Back Pain (18) · Bradycardia (17) · Carcinoma, Hepatocellular (17) · Ventricular Fibrillation (17)
Cryosurgery (13) · Defibrillators, Implantable (13) · Drug Delivery Systems (13) · Percutaneous Coronary Intervention (13) · Deep Brain Stimulation (10) · Aspirin (9) · Spinal Cord Stimulation (9) · Bronchial Thermoplasty (8) · Cryotherapy (8) · Left Atrial Appendage Closure (7) · Clopidogrel (6) · Radiofrequency Ablation (6) · Transcatheter Aortic Valve Replacement (6) · Cardiac Resynchronization Therapy (5) · Prasugrel Hydrochloride (5)
United States (410) · Germany (157) · France (130) · United Kingdom (123) · Netherlands (105) · Italy (99) · Spain (93) · Belgium (88) · Canada (86) · Australia (62) · China (54) · Japan (46) · Austria (44) · Switzerland (44) · Denmark (43)
Natalie Bloom Lyons (17) · Roshini Jain (14) · Vivek Reddy, MD (11) · Narinder S Shargill, PhD (5) · Peter M Maurer, MPH (5) · Peter Maurer, MPH (5) · Giulio Guagliumi, MD (4) · John A Ormiston, MD (4) · Mark A Turco, MD (4) · Arthur J Moss, MD (3) · Louis A Cannon, MD (3) · Pamela Grady, PhD (3) · Pichamol Jirapinyo, MD, MPH (3) · Riad Salem, MD (3) · Robert Walsh, M.D. (3)
PMID 19463432, PMID 20129555, PMID 23232250, PMID 22496083, PMID 29217001, PMID 35902169, PMID 41276366, PMID 19463387, PMID 19577985, PMID 20031730, PMID 20059766, PMID 20463331, PMID 20650436, PMID 23998657, PMID 24678999, PMID 24905795, PMID 25418910, PMID 25908064, PMID 26038537, PMID 26124205, PMID 26627989, PMID 26823498, PMID 30592353, PMID 31085321, PMID 31752643, PMID 32605387, PMID 33636137, PMID 35460884, PMID 37354778, PMID 39968829, PMID 12831818, PMID 14563591, PMID 14760193, PMID 15152059, PMID 15547547, PMID 1568614, PMID 16160130, PMID 16325694, PMID 16327043, PMID 16531618, PMID 16684026, PMID 16836672, PMID 16880336, PMID 16892434, PMID 16980116, PMID 17448368, PMID 17517341, PMID 17671809, PMID 17901415, PMID 18222352
2016 (2), 2019 (2), 4UH3NS121563-02 (1), K23DK095148 (1), R37NS040894 (1), U01HL088476 (1), U01HL107407 (1)