1739 completed, 260 recruiting, 245 terminated, 144 withdrawn. 1318 Not applicable, 327 Phase 2, 196 Phase 4, 193 Phase 1, 97 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Adapting a Telehealth Intervention for Suicide Prevention Among Patients With Alcohol Use Disorder in Tanzania IDEAS-AUD - Alcohol Use Disorder, Suicide Prevention | Not applicable | Not yet recruiting | Duke University | 30 | 2027-08-01 | 2026-03-17 |
| Feasibility of a Dyadic Music-based Intervention for Persons Living With Dementia and Their Care Partners Dyadic Music-based Intervention (MBI), Reminiscence Activity - Dementia | Not applicable | Not yet recruiting | Duke University | 60 | 2027-08-01 | 2026-10-05 |
| Teams Engaged in Accessible Mental Health Interventions for Lupus Erythematosus and Dermatomyositis Stress TEAM-LEADS - Lupus, Dermatomyositis, Juvenile | Not applicable | Not yet recruiting | Duke University | 25 | 2027-02-01 | 2026-05-27 |
| The Community Paramedic Response and Overdose Outreach With Supportive Medical-Legal Services Study Community Paramedic Standard of Care (CP SOC), CROSSROADS - Opioid Use Disorder, Overdose, Drug | Not applicable | Not yet recruiting | Duke University | 400 | 2027-02-01 | 2026-10-14 |
| Tailored mHealth Coaching and Social Resource Support in Kidney Transplantation mHealth app plus personalized coaching, Social work support - Kidney Transplant | Not applicable | Not yet recruiting | Duke University | 339 | 2027-02-01 | 2026-09-11 |
| Combating Related Epidemics in HCV Cepheid GeneXpert HCV Test, Abbott Determine HIV - 1/2 Ag/Ab, Abbott Determine HbsAg 2 - HIV - Human Immunodeficiency Virus, Hepatitis B Virus (HBV) | Phase 4 | Not yet recruiting | Duke University | 1280 | 2027-01-20 | 2026-10-15 |
| Integrating iSYV Within HIV Clinical Care for Youth Living With HIV in Tanzania iSYV (integrated Sauti ya Vijana; The Voice of Youth), mHealth, eSOC - HIV -1 Infection, Mental Health Issue | Not applicable | Not yet recruiting | Duke University | 5000 | 2027-01-10 | 2026-06-02 |
| Dosing and Deployment Trial: A Home-based Optokinetic Treatment Optokinetic stimulation - Spatial Neglect | Not applicable | Not yet recruiting | Duke University | 90 | 2027-01-04 | 2026-06-25 |
| Mitigating Racial Disparities in Shared Decision Making in the Intensive Care Unit Shared decision making tip sheet - Health Care Disparities | Not applicable | Not yet recruiting | Duke University | 106 | 2027-01-04 | 2026-06-10 |
| Self-directed Mobile Mindfulness to Address ICU Survivors' Psychological Distress Lift mobile mindfulness, Enlighten Recovery education program - Critical Illness, Heart Failure | Not applicable | Not yet recruiting | Duke University | 450 | 2027-01-01 | 2026-07-08 |
| Lattice Radiotherapy for Adults With Large Tumors Lattice Radiation Therapy (LRT) - Large Tumor, Palliative Radiotherapy | Not applicable | Not yet recruiting | Duke University | 25 | 2027-01-01 | 2026-09-08 |
| Study of QL Analgesic Response and Extent Quadratus Lumborum with 1.5% Lidocaine - Acute Pain, Postoperative Pain | Phase 4 | Not yet recruiting | Duke University | 25 | 2027-01-01 | 2026-07-08 |
| The Hear Clear Study Signal-to-Noise Ratio Enhancement (SNR+), Signal-to-Noise Ratio Neutral (SNR-) - Hearing Loss | Not applicable | Not yet recruiting | Duke University | 125 | 2027-01-01 | 2026-09-21 |
| Food DNA Digestion Reconstitutable food powder - Digestion Rate | Not applicable | Not yet recruiting | Duke University | 20 | 2027-01-01 | 2026-08-07 |
| Targeted Nerve Injection to the Knee (Nerve to Vastus Medialis): Comparing Two Adductor Canal Block Approaches Traditional adductor canal block, NVM (nerve to vastus medialis) targeted adductor canal block, Chloroprocaine Injection - Anesthesia, Local | Phase 4 | Not yet recruiting | Duke University | 25 | 2027-01-01 | 2026-08-27 |
| Addressing Barriers to Anti-hypertensive Medication Adherence Among PLWH Who Have Achieved Viral Suppression Hypertension control through education and monitoring - Hypertension, HIV-1-infection | Not applicable | Not yet recruiting | Duke University | 60 | 2026-12-03 | 2026-10-01 |
| Vaginal Dose De-escalation During Brachytherapy for Cervical Cancer radiation dose de-escalation - Cervical Cancer | Not applicable | Not yet recruiting | Duke University | 20 | 2026-12-01 | 2026-10-02 |
| ORASIS in Breast Reconstruction Use of ORASIS Device - DIEP Flap, Breast Reconstruction | Not applicable | Not yet recruiting | Duke University | 30 | 2026-12-01 | 2026-07-01 |
| Differences in Mechanistic Measures (Oxytocin and Cortisol) of Therapeutic Alliance Between A Talk-Based Therapy and Soft-Tissue Mobilization in Individuals With Chronic Spinal Pain Massage, Talk-based therapy - Spine, Low Back Pain | Not applicable | Not yet recruiting | Duke University | 25 | 2026-12-01 | 2026-10-16 |
| IDEAS for Hope to Reduce Suicide Risk and Improve HIV Care Engagement in Tanzania IDEAS for Hope, Safety Planning Intervention - HIV - Human Immunodeficiency Virus, Suicide Prevention | Not applicable | Not yet recruiting | Duke University | 600 | 2026-12-01 | 2026-10-14 |
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Breast Neoplasms (79) · Obesity (79) · Depression (77) · Brain Neoplasms (71) · Motor Activity (71) · Heart Failure (66) · Cardiovascular Diseases (58) · Glioblastoma (57) · Neoplasms (57) · Glioma (53) · Hypertension (53) · Prostatic Neoplasms (52) · Anxiety Disorders (51) · Pain (51) · COVID-19 (42)
Exercise (33) · Temozolomide (27) · Tobacco Use Cessation Devices (26) · Bevacizumab (25) · Educational Status (20) · Radiotherapy (19) · Cognitive Behavioral Therapy (18) · Sodium Chloride (16) · Bupropion (15) · Dexamethasone (15) · Standard of Care (15) · Sertraline (14) · Influenza Vaccines (13) · Nicotine (12) · Transcranial Magnetic Stimulation (12)
United States (2326) · Canada (49) · Kenya (32) · Tanzania (24) · China (20) · India (13) · Australia (12) · Singapore (12) · United Kingdom (12) · Germany (10) · Italy (8) · Netherlands (8) · South Africa (8) · Spain (8) · Brazil (7)
Henry S. Friedman, MD (19) · David A. Reardon, MD (11) · Cynthia A Toth, MD (9) · Manisha Palta, MD (9) · Priya Kishnani, MD (9) · Eugene Braunwald, MD (8) · Isaac Lipkus, PhD (8) · Jed E Rose, Ph.D. (8) · Adam Wax, Ph.D. (7) · Annick Desjardins, MD, FRCPC (7) · Daniel George, MD (7) · Darell D. Bigner, MD, PhD (7) · Michael Harrison, MD (7) · Rebecca Shelby, PhD (7)
PMID 22302620, PMID 25890798, PMID 26111071, PMID 26512712, PMID 26927285, PMID 37072349, PMID 37142273, PMID 42282195, PMID 17182834, PMID 18477783, PMID 19637244, PMID 20122025, PMID 21637107, PMID 22376375, PMID 22419878, PMID 22883447, PMID 25543972, PMID 26041600, PMID 27514750, PMID 28433500, PMID 29793970, PMID 29976553, PMID 32985131, PMID 33472650, PMID 33714749, PMID 33884617, PMID 34611902, PMID 35224730, PMID 35262490, PMID 35688625, PMID 35998103, PMID 36907457, PMID 36907833, PMID 37148652, PMID 37287104, PMID 37318215, PMID 38485730, PMID 38489667, PMID 38805199, PMID 38815760, PMID 39052647, PMID 39213738, PMID 39974080, PMID 41719044, PMID 41944009, PMID 42015271, PMID 42090156, PMID 42454489, PMID 42684112, PMID 11828001
P50DA027840 (9), U01HL084904 (7), U01HG010225 (5), U24HD069031 (5), U54MD012530 (5), UM1AI104681 (5), P30AG064201 (4), P30AI064518 (4), U01HD069031 (4), U19MH108206 (4), 5UM1AI104681 (3), M01RR000030 (3), OT2HL156812 (3), P01HL036587 (3), P01NR010948 (3)