33273 completed, 11399 unknown, 7800 recruiting, 3970 terminated. 24520 Not applicable, 7021 Phase 2, 5217 Phase 3, 4907 Phase 4, 4033 Phase 1.
Follow Cardiovascular Diseases: new trials by email Literature Review of Cardiovascular Diseases trials Research Report on Cardiovascular Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Inhibiting GABA Transaminase to Relieve Obesity Induced Hyperinsulinemia and Insulin Resistance Vigabatrin Pill, Placebo oral tablet - Hyperinsulinism, Insulin Resistance | Phase 2 | Withdrawn | University of Arizona | 2030-04-15 | 2025-07-30 | |
| FGF-1 for Intramuscular Injection for the Treatment of Peripheral Arterial Disease FGF-1, Placebo - Peripheral Arterial Disease, Stenosis | Phase 1 / Phase 2 | Not yet recruiting | Venturis Therapeutics, Inc. | 24 | 2028-10-15 | 2026-08-19 |
| The Effect of Sympathetic Modulation on Cerebral Vasospasm Secondary to Aneurysmal Subarachnoid Hemorrhage Vectris trial leads and stimulation, Sham - Vasospasm, Cerebral, Aneurysmal Subarachnoid Hemorrhage | Not applicable | Suspended | University of Alabama at Birmingham | 25 | 2028-07-31 | 2026-09-24 |
| Impact of Iron Supplementation on Right Ventricular Function and Exercise Performance in Hypoxia Ferrous sulfate 325mg - Right Ventricular Dysfunction, Hypoxia | Early Phase 1 | Not yet recruiting | University of Colorado, Denver | 5 | 2028-03-01 | 2026-04-29 |
| Effect of Ginger on Heavy Menstrual Bleeding in Women With Coagulation Disorders Ginger, Placebo - Women With Coagulation Disorders | Early Phase 1 | Not yet recruiting | University of Valladolid | 74 | 2028-02-01 | 2026-05-19 |
| MM-CARE: Cardiovascular Risk Assessment in Adults With Multiple Myeloma Oncology-Embedded Cardiovascular Risk Assessment Pathway, Primary Care Provider-Directed Cardiovascular Risk Assessment Pathway - Multiple Myeloma, Heart Disease Risk Factors | Not applicable | Not yet recruiting | University of Vermont Medical Center | 33 | 2028-02-01 | 2026-08-25 |
| Real-world Study to Describe the Effectiveness and Safety Outcomes of Jardiance in Chinese Patients With Heart Failure and Preserved Ejection Fraction Heart Failure, Preserved Ejection Fraction | Not yet recruiting | Boehringer Ingelheim | 3000 | 2028-01-31 | 2026-09-16 | |
| Standalone Thoracoscopic Left Atrial Appendage Closure Versus Medical Therapy in Atrial Fibrillation Video-assisted thoracoscopic closure of the left atrial appendage using a closure device and discontinuation of treatment if the patient is treated with OAC - ATRIAL APPENDAGE CLOSURE for ATRIAL FIBRILLATION, Oral Anticoagulation | Not applicable | Not yet recruiting | Region Skane | 936 | 2028-01-01 | 2026-07-15 |
| AI-assisted Subtyping-directed Precision Treatment in Acute Aortic Dissection Ulinastatin and Thymalfasin, Ulinastatin - Aortic Aneurysm and Dissection | Not applicable | Not yet recruiting | Nanjing Medical University | 300 | 2027-12-31 | 2026-02-02 |
| Timing for Computed Tomography and Post-Resuscitation Care on Short-Term Outcomes in Out-of-Hospital Cardiac Arrest Out of Hospital Cardiac Arrest, Computed Tomography | Not yet recruiting | National Taiwan University Hospital | 5000 | 2027-12-31 | 2025-11-19 | |
| Study to Evaluate the effIcacy and Safety of Abelacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral Anticoagulation Abelacimab - Atrial Fibrillation (AF) | Phase 3 | Not yet recruiting | Novartis Pharmaceuticals | 2500 | 2027-12-30 | 2026-07-31 |
| Essential Acute Stroke Care in Low Resource Settings: a Pilot studY Acute stroke care Intervention arm - Acute Stroke | Not applicable | Not yet recruiting | The George Institute | 300 | 2027-12-30 | 2026-06-11 |
| Vitamin B6 on Exercise Pressor Reflex on Leg Ischemia-reperfusion Vitamin B6 25 MG, Vitamin B6 50 MG, Vitamin B6 100 MG - Ischemia Reperfusion Injury, Peripheral Artery Disease | Early Phase 1 | Not yet recruiting | Milton S. Hershey Medical Center | 30 | 2027-12-01 | 2026-03-17 |
| REstoring Flow by REvascularization With Submaximal Angioplasty in Hemodynamic IntraCranial Atherosclerotic Stenosis Submaximal balloon angioplasty - Intracranial Atherosclerotic Disease, Stroke | Not applicable | Not yet recruiting | Case Western Reserve University | 159 | 2027-10-01 | 2025-11-04 |
| Veteran Centered Meal Intervention in Chronic Kidney Disease Medically tailored meals (MTMs) - Chronic Kidney Disease | Not applicable | Not yet recruiting | VA Office of Research and Development | 100 | 2027-10-01 | 2026-09-03 |
| Safety And Field Evaluation of Plasma Lyophilized for Acute and Surgical Management Applications Freeze-Dried Plasma, Conventional Plasma - Thromboembolic Event, FDP | Phase 4 | Not yet recruiting | Teleflex | 867 | 2027-10-01 | 2026-09-30 |
| The Feasibility and Effects of Exercise on Patients Suffering From Multiple Myeloma Individual Exercise, Group Exercise - Multiple Myeloma | Not applicable | Suspended | Medical University of Vienna | 45 | 2027-09-01 | 2026-10-09 |
| COOLing of the Ischemic PENumbra in Patients With Acute Ischemic Stroke. PEN-Cool Conductive Head-and-Neck Cooling System, Standard Reperfusion Therapy / Routine Care - Acute Ischemic Stroke | Not applicable | Not yet recruiting | Christian Medical College and Hospital, Ludhiana, India | 55 | 2027-09-01 | 2026-09-28 |
| Mobile Health Management of Hypertension mHealth Coaching Intervention, Enhanced Usual Care - Hypertension | Not applicable | Not yet recruiting | University of Chicago | 40 | 2027-09-01 | 2026-08-10 |
| Fibroblast Growth Factor-1 (FGF-1) for the Treatment of Coronary Heart Disease Human Recombinant Fibroblast Growth Factor-1 (FGF 1-141) - low dose, Human Recombinant Fibroblast Growth Factor-1 (FGF1-141) - high dose, Placebo - Coronary Disease, Coronary Heart Disease | Phase 2 | Not yet recruiting | Venturis Therapeutics, Inc. | 150 | 2027-09-01 | 2026-08-19 |
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Stroke (7796) · Hypertension (5918) · Heart Failure (5584) · Coronary Artery Disease (4729) · Atrial Fibrillation (3821) · Multiple Myeloma (3659) · Ischemic Stroke (2541) · Heart Diseases (2133) · Myocardial Infarction (1960) · Diabetes Mellitus (1946) · Coronary Disease (1498) · Atherosclerosis (1482) · Acute Coronary Syndrome (1460) · Peripheral Arterial Disease (1356)
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Dexamethasone (910) · Aspirin (604) · Exercise (579) · Clopidogrel (548) · Standard of Care (499) · Bortezomib (483) · Lenalidomide (462) · Cyclophosphamide (426) · Blood Specimen Collection (394) · Sodium Chloride (375) · Rivaroxaban (373) · Amlodipine (365) · Atorvastatin (340) · Saline Solution (318) · Ticagrelor (301)
National Heart, Lung, and Blood Institute (NHLBI) (683) · Assistance Publique - Hôpitaux de Paris (457) · Mayo Clinic (457) · Assiut University (455) · Abbott Medical Devices (416) · National Taiwan University Hospital (302) · Boston Scientific Corporation (292) · Bayer (287) · Novartis Pharmaceuticals (269) · Yonsei University (269) · AstraZeneca (264) · Boehringer Ingelheim (264) · Brigham and Women's Hospital (257) · University of Pennsylvania (254) · VA Office of Research and Development (254)
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Vivek Reddy, MD (38)
PMID 33175411, PMID 34813082, PMID 42573020, PMID 35224730, PMID 37870112, PMID 36326435, PMID 36398903, PMID 31867054, PMID 32905623, PMID 33769555, PMID 35244208, PMID 36645250, PMID 38682786, PMID 41114449, PMID 32499241, PMID 34184251, PMID 34196963, PMID 36700520, PMID 33107592, PMID 33337539, PMID 33779986, PMID 34932836, PMID 35857365, PMID 39968829, PMID 18190818, PMID 32860505, PMID 33502773, PMID 38018702, PMID 40875095, PMID 42035974, PMID 19717846, PMID 20961243, PMID 33089502, PMID 34022170, PMID 34487721, PMID 37059239, PMID 37330702, PMID 37565307, PMID 38770818, PMID 39963789, PMID 16731270, PMID 21899409, PMID 31081589, PMID 31535829, PMID 33357481, PMID 34447992, PMID 34515113, PMID 38189593, PMID 38989575, PMID 39526682
2023 (228), 2018 (152), 2019 (138), 2025 (135), 2016 (129), 2017 (118), 2009 (103), 2014 (96), 2015 (94), 2008 (69), P30CA015083 (51), 2005 (44), U10CA180820 (43), P30CA015704 (34), 2004 (25)