1464 completed, 413 unknown, 327 recruiting, 315 terminated. 1197 Phase 2, 656 Phase 3, 537 Phase 1, 471 Phase 4, 348 Not applicable.
Follow this drug Literature Review of Dexamethasone trials Research Report on Dexamethasone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing the Investigational Medication Combination of Daratumumab and Teclistamab Compared to the Usual Treatment (Daratumumab, Pomalidomide, Dexamethasone or Daratumumab, Carfilzomib, Dexamethasone) for Patients With High-risk Multiple Myeloma Refractory or in First Relapse Biospecimen Collection, Bone Marrow Biopsy, Carfilzomib - Recurrent Multiple Myeloma, Refractory Multiple Myeloma | Phase 2 | Recruiting | National Cancer Institute (NCI) | 80 | 2027-05-22 | 2026-10-20 |
| Testing an Experimental Approach to Treat Patients With Plasma Cell Leukemia, The QUANTUM Trial Autologous Hematopoietic Stem Cell Transplantation, Biospecimen Collection, Bone Marrow Aspiration - Plasma Cell Leukemia | Phase 2 | Recruiting | National Cancer Institute (NCI) | 74 | 2027-04-20 | 2026-10-07 |
| Testing the Investigational Medication Combination of Teclistamab and Pomalidomide Compared to the Usual Treatment (Carfilzomib, Pomalidomide, and Dexamethasone) for Patients With Multiple Myeloma Who Have Relapsed Shortly After Treatment Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Recurrent Multiple Myeloma, Refractory Multiple Myeloma | Phase 1 / Phase 2 | Recruiting | National Cancer Institute (NCI) | 162 | 2027-04-12 | 2026-10-16 |
| FPS-ZM1 With or Without Dexamethasone for Controlling Post Operative Cerebral Edema in Patients With Glioblastoma Biospecimen Collection, Computed Tomography, Dexamethasone - Glioblastoma, Malignant Glioma | Phase 1 | Not yet recruiting | City of Hope Medical Center | 24 | 2027-02-17 | 2026-08-27 |
| Liposomal Bupivacaine vs Perineural Adjuvants in Adductor Canalf and iPACK Blocks in Total Knee Arthroplasty Liposomal Bupivacaine, Bupivacaine, Clonidine, Epinephrine, Buprenorphine and Dexamethasone (BPV-CEBD) Combination - Knee Arthroplasty, Total | Phase 4 | Not yet recruiting | Wake Forest University Health Sciences | 90 | 2027-02-01 | 2026-08-25 |
| Prevent Wheeze Trial Dexamethasone 0.6 mg/kilogram body weight single dose, Placebo - Lower Respiratory Tract Infection (LRTI), Recurrent Wheezing | Phase 4 | Not yet recruiting | Norwegian University of Science and Technology | 486 | 2027-02-01 | 2026-10-05 |
| Testing the Use of High Dose Testosterone Followed by Darolutamide Compared to the Usual Care for Patients With Metastatic Prostate Cancer Abiraterone Acetate, Biospecimen Collection, Bone Scan - Metastatic Castration-Resistant Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 2 / Phase 3 | Not yet recruiting | ECOG-ACRIN Cancer Research Group | 432 | 2027-01-06 | 2026-10-01 |
| Effect Of Intracuff Dexamethasone On Postoperative Sore Throat In Patients Undergoing Laparoscopic Cholecystectomy Dexamethasone (0.1 mg/kg), Normal Saline (0.9% NaCl) - Postoperative Sore Throat, Cough, Hoarseness | Not applicable | Not yet recruiting | B.P. Koirala Institute of Health Sciences | 40 | 2027-01-01 | 2026-08-24 |
| A Trial to Evaluate Safety and Efficacy of Anitocabtagene Autoleucel Versus Standard of Care in Newly Diagnosed Multiple Myeloma Anitocabtagene autoleucel, Daratumumab, Bortezomib - Newly Diagnosed Multiple Myeloma | Phase 3 | Not yet recruiting | Kite, A Gilead Company | 600 | 2027-01-01 | 2026-10-21 |
| Premedication With Dexamethasone for Preventing Interstitial Lung Disease in Patients With Breast Cancer Treated With Trastuzumab Deruxtecan Dexamethasone, antiemetic premedication, T-DXd - Breast Cancer, Interstitial Lung Disease (ILD) | Phase 3 | Not yet recruiting | Mario Negri Institute for Pharmacological Research | 244 | 2026-12-20 | 2026-10-19 |
| Verification of the Efficacy/Safety of the Mixed Drug Injectable Delivery Vehicle for Treating Intractable Hearing Loss Dexamethasone, Hyaluronic acid, Indocyanine green(ICG) - Hearing Loss, Sensorineural, Hearing Loss, Sudden | Phase 1 / Phase 2 | Withdrawn | Seoul National University Hospital | 2026-12-15 | 2026-05-22 | |
| Etenta-Isa-VRd in Newly Diagnosed High-Risk Multiple Myeloma Etentamig, Isatuximab, Bortezomib + Lenalidomide + Dexamethasone - Myeloma Multiple, Myeloma | Phase 1 / Phase 2 | Not yet recruiting | Universitätsklinikum Hamburg-Eppendorf | 220 | 2026-12-01 | 2026-05-20 |
| Evaluation of Iopofosine I 131 vs. R-CD in WM Patients Iopofosine I 131, Rituximab (active comparator), Cyclophosphamate - Waldenstrom Macroglobulinaemia, Waldenstrom Macroglobulinemia | Phase 3 | Not yet recruiting | Cellectar Biosciences, Inc. | 219 | 2026-12-01 | 2026-08-14 |
| A Study to Evaluate Adverse Events and Change in Disease Activity With Injected Etentamig Plus Oral Pomalidomide Versus Standard Therapies in Adults With Relapsed or Refractory Multiple Myeloma Etentamig, Pomalidomide, Daratumumab - Relapsed or Refractory Multiple Myeloma | Phase 3 | Not yet recruiting | AbbVie | 520 | 2026-11-30 | 2026-07-27 |
| Study to Evaluate Change in Disease Activity and Adverse Events of Subcutaneous Etentamig Compared With Daratumumab Plus Cyclophosphamide Plus Bortezomib Plus Dexamethasone (Dara-CyBorD) in Adults With Amyloid Light Chain (AL) Amyloidosis Etentamig, Daratumumab, Cyclophosphamide - Amyloid Light Chain (AL) Amyloidosis | Phase 3 | Not yet recruiting | AbbVie | 370 | 2026-11-29 | 2026-08-28 |
| A Clinical Trial of MK-2750 in Participants With Advanced Solid Tumors (MK-2750-002) MK-2750, 5-HT3 serotonin receptor antagonist, NK-1 receptor antagonist - Advanced Solid Tumors, Malignant Neoplasm | Phase 1 / Phase 2 | Not yet recruiting | Merck Sharp & Dohme LLC | 300 | 2026-11-16 | 2026-10-15 |
| Epcoritamab in Combination With R-CHOP for Patients With Aggressive Non-Hodgkin Lymphoma Rituximab, Cyclophosphamide, Hydroxydaunorubicin, Oncovin, Prednisolone (R-CHOP), Epcoritamab, Dexamethasone - Non-Hodgkin's B-cell Lymphoma, Lymphoma Non-Hodgkin | Phase 2 | Not yet recruiting | Carrie Ho, MD | 20 | 2026-11-15 | 2026-10-01 |
| A Clinical Trial of MK-6255 to Treat Endometrial and Ovarian Cancer (MK-6255-001) MK-6255, CD8 PET Tracer, Acetaminophen - Ovarian Neoplasms, Endometrial Neoplasms | Phase 1 | Not yet recruiting | Merck Sharp & Dohme LLC | 80 | 2026-11-13 | 2026-10-13 |
| DiEtary Mimicry by Glucocorticoid Modulation Evaluation in ER+ Metastatic Breast Cancer Treatment: Efficacy and Response (DEMETER Trial) Dexamethasone (Oral) - Breast Cancer | Phase 2 | Not yet recruiting | The Netherlands Cancer Institute | 80 | 2026-11-01 | 2026-08-25 |
| Low Dose Dexamethasone for the Prevention of Cytokine Release Syndrome Associated With Tebentafusp Dexamethasone - Uveal Melanoma, Metastatic | Phase 2 | Not yet recruiting | University of California, San Diego | 34 | 2026-11-01 | 2026-09-03 |
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Multiple Myeloma (822) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (173) · Pain, Postoperative (166) · Recurrence (152) · Vomiting (113) · Neoplasms, Plasma Cell (112) · Postoperative Nausea and Vomiting (103) · Lymphoma (94) · Leukemia (93) · Neoplasms (85) · Nausea (71) · Burkitt Lymphoma (59) · Pain (57) · Lymphoma, Non-Hodgkin (52) · Immunoglobulin Light-chain Amyloidosis (51)
M.D. Anderson Cancer Center (87) · National Cancer Institute (NCI) (59) · Assiut University (51) · Mayo Clinic (46) · Celgene (38) · Merck Sharp & Dohme LLC (37) · Janssen Research & Development, LLC (35) · Memorial Sloan Kettering Cancer Center (31) · Allergan (29) · Children's Oncology Group (29) · PETHEMA Foundation (26) · AbbVie (25) · Amgen (24) · Bristol-Myers Squibb (24) · Dana-Farber Cancer Institute (24)
United States (1376) · China (320) · Canada (288) · France (250) · Spain (237) · Germany (236) · Italy (210) · Australia (189) · United Kingdom (187) · South Korea (152) · Poland (140) · Netherlands (138) · Greece (136) · Egypt (126) · Denmark (122)
PMID 41671463, PMID 33357481, PMID 39121442, PMID 22689675, PMID 35622074, PMID 19005182, PMID 29567784, PMID 31221778, PMID 33206392, PMID 34002866, PMID 34289038, PMID 37890117, PMID 38446568, PMID 40501401, PMID 40812353, PMID 19846889, PMID 23007406, PMID 24802773, PMID 24970932, PMID 32678530, PMID 33242441, PMID 34473343, PMID 35549810, PMID 35876974, PMID 39229471, PMID 40226119, PMID 12944568, PMID 14504060, PMID 15117425, PMID 16105981, PMID 16314401, PMID 16421426, PMID 16766588, PMID 17077333, PMID 18032762, PMID 18032763, PMID 18799726, PMID 19144982, PMID 19433688, PMID 19546402, PMID 19901114, PMID 20154213, PMID 21273172, PMID 21719599, PMID 22141732, PMID 22442346, PMID 22493293, PMID 22579125, PMID 22674807, PMID 23024237
2023 (53), 2019 (24), 2016 (23), 2014 (21), 2017 (20), 2025 (19), P30CA015083 (19), U10CA098543 (19), U10CA032102 (18), U10CA180886 (16), 2018 (15), 2015 (14), 2009 (13), U10CA180820 (12), 2008 (11)