322 completed, 67 unknown, 48 terminated, 32 recruiting. 137 Phase 4, 136 Phase 3, 88 Phase 2, 84 Not applicable, 48 Phase 1.
Follow this drug Literature Review of Pregabalin trials Research Report on Pregabalin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Pregabalin Combined With Educational and Behavioral Intervention for Bladder Pain Syndrome/Interstitial Cystitis Educational and Behavioral Management Program (EBMP), Pregabalin - Bladder Pain Syndrome, Pregabalin | Phase 1 | Not yet recruiting | Beijing Tiantan Hospital | 200 | 2026-12-31 | 2026-08-07 |
| Human Experimental Models of Pain (HEMP) Placebo, Naproxen, Pregabalin - Acute Pain | Not applicable | Not yet recruiting | National Center for Complementary and Integrative Health (NCCIH) | 25 | 2026-10-26 | 2026-10-21 |
| Comparison of Two Postoperative Care Strategies After Breast Surgery Patient Education, Paracetamol, Dexketoprofen - Postoperative Pain, Pain Management | Not applicable | Recruiting | Moumtzidou Maria Aikaterini | 108 | 2026-10-19 | 2026-10-20 |
| An Artificial Intelligence Driven Approach to Optimize Patient Selection for a Transitional Pain Service TPS-Select, Pharmacologic Pain Management, Interventional Pain Procedures - Postsurgical Pain Management, Postsurgical Pain, Chronic | Phase 3 | Not yet recruiting | University of California, San Francisco | 474 | 2026-10-01 | 2026-10-09 |
| Pregabalin for Chronic Pelvic Pain in Women Pregabalin, Behavioral Treatment - Chronic Pelvic Pain, Chronic Pelvic Pain Syndrome | Not applicable | Not yet recruiting | Beijing Tiantan Hospital | 308 | 2026-10-01 | 2026-10-20 |
| A 2x2 Factorial, Randomized, Open-label Trial to Evaluate Neuromodulators and Cough Control Therapy in Patients With Refractory or Unexplained Chronic Cough Morphine Sulphate, Morphine Sulphate + Cough Control Therapy, Pregabalin - Cough, Refractory Chronic Cough | Phase 4 | Not yet recruiting | McMaster University | 124 | 2026-09-30 | 2026-10-19 |
| Gabapentin and Pregabalin Effects on Inflammation and Cardiac Function in Peripheral Neuropathic Pain Gabapentin, Pregabalin - Peripheral Neuropathic Pain | Not yet recruiting | Giresun University | 75 | 2026-08-15 | 2026-08-10 | |
| A Clinical Trial to Evaluate the Efficacy and Safety of HL-1186 Tablet in the Treatment of Postherpetic Neuralgia HL-1186, HL-1186 placebo, Pregabalin capsule - Postherpetic Neuralgia ( PHN ) | Phase 2 | Recruiting | Shanghai Yidian Pharmaceutical Technology Development Co., Ltd. | 200 | 2026-08-01 | 2026-08-11 |
| Pharmacokinetics of Y-4 Tablets With Pregabalin Capsules and Riluzole Tablets in U.S. Healthy Participants Y-4 tablet, Pregabalin capsule, Riluzole tablet - Healthy Male and Female Subjects | Phase 1 | Not yet recruiting | Neurodawn Pharmaceutical Co., Ltd. | 11 | 2026-06-30 | 2026-06-01 |
| Effect of Pregabalin on Optic Nerve Sheath Diameter in Craniotomy Patients. Pregabalin, Placebo - Pregabalin, Optic Nerve Sheath Diameter Measurement | Not applicable | Active not recruiting | Benha University | 100 | 2026-05-25 | 2026-06-08 |
| Efficacy and Safety of the N0750 Compared to Monotherapies in the Treatment of Painful Diabetic Peripheral Neuropathy N0750, Cymbalta®, Lyrica® - Painful Diabetic Peripheral Neuropathy (PDPN) | Phase 3 | Withdrawn | Eurofarma Laboratorios S.A. | 2026-04-01 | 2025-12-18 | |
| A Study of HRS-2129 in Patients With Diabetic Peripheral Neuropathic Pain HRS-2129 Tablets, HRS-2129 Placebo, Pregabalin Capsules - Diabetic Peripheral Neuropathic Pain | Phase 1 | Recruiting | Shandong Suncadia Medicine Co., Ltd. | 168 | 2026-03-24 | 2026-04-15 |
| Adding Amantadine or Duloxetine to Pregabalin on Occurrence of Post Mastectomy Pain Syndrome Pregabalin, Pregabalin + Amantadine, Pregabalin + Duloxetine - Amantadine, Duloxetine | Not applicable | Recruiting | Cairo University | 150 | 2026-02-21 | 2026-02-24 |
| Y-4 to Treat the Postherpetic Neuralgia Y-4 tables, Pregabalin - Postherpetic Neuralgia, Y-4 | Phase 2 | Recruiting | Neurodawn Pharmaceutical Co., Ltd. | 160 | 2026-02-02 | 2026-05-13 |
| SPENDD: Quantitative Sensory Testing and Analgesic Response for Painful Peripheral Neuropathy. Pregabalin, Duloxetine, Placebo - Painful Peripheral Neuropathy, Diabetic Peripheral Neuropathic Pain (DPN) | Phase 2 | Recruiting | University of Rochester | 190 | 2026-02-02 | 2026-09-16 |
| Effectiveness of Opioid vs Pregabalin Plus Naproxen Sodium in Pain Management of Oral Cancer Patients Tramadol, Pregabalin + Naproxen Sodium - Oral Cancer, Oral Cavity Cancer | Not applicable | Enrolling by invitation | Mayo Hospital Lahore | 98 | 2026-02-01 | 2026-05-26 |
| Efficacy and Safety of Pregabalin/Tizanidine vs. Pregabalin in Patients With Fibromyalgia Pregabalin, Pregabalin with tizanidine - Fibromyalgia, Pregabalin | Not applicable | Not yet recruiting | Beijing Tiantan Hospital | 164 | 2026-01-30 | 2026-02-04 |
| Oral Melatonin Versus Oral Pregabalin on Postoperative Pain and Anxiety Following Spine Surgery Placebo capsule, Melatonin capsule, Pregabalin capsule - Oral, Melatonin | Not applicable | Recruiting | Tanta University | 105 | 2026-01-17 | 2026-01-21 |
| The Efficacy and Safety of Pregabalin Combined With Toludesvenlafaxine in Patients With Fibromyalgia Pregabalin, Pregabalin with toludesvenlafaxine - Fibromyalgia, Pregabalin | Not applicable | Recruiting | Beijing Tiantan Hospital | 384 | 2025-10-20 | 2025-11-17 |
| Efficacy and Safety of Mirogabalin in Diabetic Peripheral Neuropathic Pain Mirogabalin, Pregabalin - Diabetic Peripheral Neuropathic Pain (DPNP) | Phase 4 | Recruiting | Bangladesh Medical University | 78 | 2025-10-01 | 2026-03-09 |
Showing 20 of 499. Sign in to see all of them.
Pain (74) · Pain, Postoperative (67) · Neuralgia (63) · Fibromyalgia (49) · Diabetic Neuropathies (24) · Neuralgia, Postherpetic (20) · Epilepsies, Partial (19) · Chronic Pain (16) · Epilepsy (16) · Agnosia (15) · Anxiety Disorders (10) · Seizures (10) · Acute Pain (9) · Diabetes Mellitus (8) · Spinal Cord Injuries (8)
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (104) · Pfizer (22) · Beijing Tiantan Hospital (15) · Cairo University (6) · Yuhan Corporation (6) · Daiichi Sankyo (5) · Tel-Aviv Sourasky Medical Center (5) · Eli Lilly and Company (4) · GL Pharm Tech Corporation (4) · Mansoura University (4) · McMaster University (4) · The Catholic University of Korea (4) · Assiut University (3) · Glostrup University Hospital, Copenhagen (3) · Guang'anmen Hospital of China Academy of Chinese Medical Sciences (3)
United States (145) · Canada (49) · South Korea (45) · China (41) · Egypt (37) · Germany (36) · Spain (29) · United Kingdom (27) · France (26) · Italy (25) · Belgium (24) · Czechia (24) · India (24) · Netherlands (24) · Mexico (23)
Ole Mathiesen, MD (3) · Ruquan Han, M.D., Ph D. (3) · Yong In, MD, PhD (3) · David Yarnitsky, Professor (2) · Elena Theodorou, MD (2) · Jorge E Zamora, MD (2) · Katie Murray, DO (2) · Michael Camilleri, MD (2) · Ronald B George, MD FRCPC (2) · Theresa A Zesiewicz, MD (2)
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