4976 completed, 1381 unknown, 1227 recruiting, 557 not yet recruiting. 4666 Not applicable, 826 Phase 2, 810 Phase 4, 691 Phase 3, 322 Phase 1.
Follow Neurobehavioral Manifestations: new trials by email Literature Review of Neurobehavioral Manifestations trials Research Report on Neurobehavioral Manifestations
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Post-surgical Delirium in Patients Undergoing Radical Cystectomy. Radical cystectomy. - Delirium, Radical Cystectomy | Not yet recruiting | University of Alexandria | 100 | 2028-11-25 | 2025-04-03 | |
| Post-surgical Delirium in Patients Undergoing Open Heart Surgery. Open heart surgery - Delirium, Open Heart Surgery | Not yet recruiting | University of Alexandria | 300 | 2028-10-01 | 2025-04-03 | |
| RCT: Trazodone vs Quetiapine vs Placebo for Treating ICU Delirium (TraQ) Trazodone, Quetiapine, Placebo - Delirium, Morality | Phase 4 | Withdrawn | University of Southern California | 2028-03-01 | 2026-05-04 | |
| Sodium Lactate in Severe TBI Sodium Lactate, placebo - Traumatic Brain Injury | Phase 2 | Not yet recruiting | University of California, Los Angeles | 264 | 2028-01-10 | 2026-01-16 |
| Psilocybin After Trauma Surgery for Pain Psilocybin (Usona Institute), Postoperative analgesia - Pain Management, Postoperative Pain | Phase 1 | Not yet recruiting | Trent Emerick | 70 | 2027-12-31 | 2026-08-06 |
| Magnesium Sulfate in Pediatric Burn Dressing Changes magnesium sulfate, Normal Saline (0.9% NaCl) - Pediatric Burns | Phase 1 | Not yet recruiting | Hennepin Healthcare Research Institute | 10 | 2027-12-01 | 2026-10-09 |
| Neostigmine as an Adjuvant in Tranversus Abdominis Plane (TAP) Block in Cesarean Section Under Spinal Anesthesia Bupivacaine-Neostigmine, Bupivacaine - Analgesia | Not applicable | Not yet recruiting | Mansoura University | 58 | 2027-12-01 | 2026-02-17 |
| Regulating Together for Intellectual Disability and Autism: A Group Behavioral Therapy for for Emotion Dysregulation Regulating Together group therapy - Autism, Intellectual Disabilities With Other Behavioral Symptoms | Not applicable | Recruiting | Children's Mercy Hospital Kansas City | 10 | 2027-10-01 | 2026-09-03 |
| Real-time Ultrasound Guidance for Thoracic Epidural Blocks Real-time ultrasound guidance for thoracic epidural catheter placement. - Analgesia, Thoracic Tumors | Withdrawn | University of Chile | 2027-07-01 | 2026-05-19 | ||
| Efficacy and Safety of NTI164 in Children and Young Adults With Rett Syndrome NTI164, Placebo - RETT Syndrome With Proven MECP2 Mutation, Rett Syndrome | Phase 2 / Phase 3 | Not yet recruiting | Fenix Innovation Group | 40 | 2027-07-01 | 2026-09-09 |
| Prospective Observational Multimodal Neuromonitoring During High-Risk Adult Surgery Postoperative Cognitive Complications, Delirium | Not yet recruiting | University of Texas Southwestern Medical Center | 300 | 2027-07-01 | 2026-10-23 | |
| IT and IV Lentiviral Gene Therapy for X-ALD Intrathecal and intravenous LV gene therapy - X-linked Adrenoleukodystrophy | Not applicable | Not yet recruiting | Shenzhen Geno-Immune Medical Institute | 30 | 2027-06-01 | 2026-09-01 |
| Lateral Cord Stimulation as a New Treatment for Refractory Spastic Cerebral Palsy Lateral spinal cord surgical implant of electrodes - Cerebral Palsy, Spasticity | Not applicable | Not yet recruiting | Juan Carlos M. Andreani MD | 40 | 2027-06-01 | 2026-04-28 |
| The Clinical Impact of Serratus Anterior VS. Erector Spinae Plane Block on Pain Management of Tube Thoracostomy in Emergency Department Patients. serratus anterior plane blocks, Erector Spinae Plane Block - Thoracostomy Pain Management, Pain Management | Not applicable | Not yet recruiting | Assiut University | 80 | 2027-06-01 | 2026-09-17 |
| Concurrent Trials on Nature-Based Therapy for Inpatients in Dementia and Rehabilitation Medicine Wards Nature Immersion Therapy - Dementia, Acquired Brain Injury Including Stroke | Not applicable | Not yet recruiting | Changi General Hospital | 1600 | 2027-05-01 | 2026-03-23 |
| Testing a Peer-Support Group for Veterans Who Hear Voices Veteran Voices and Visions (VVV), Wellness Recovery Action Planning (WRAP) - Psychotic Disorders, Hallucinations, Auditory | Not applicable | Not yet recruiting | VA Office of Research and Development | 160 | 2027-04-01 | 2026-04-29 |
| Lorazepam for Delirium Prevention in Critically Ill Patients With High Anttila-Index Lorazepam 1 mg, Placebo - Delirium Confusional State | Phase 4 | Not yet recruiting | University Hospital, Basel, Switzerland | 260 | 2027-03-01 | 2026-02-27 |
| A Clinical Trial of Iron Supplementation for Youth With ADHD and Restless Sleep Ferrous Sulfate, Placebo - ADHD, Sleep Problems | Phase 1 / Phase 2 | Not yet recruiting | Hugo W. Moser Research Institute at Kennedy Krieger, Inc. | 70 | 2027-03-01 | 2026-05-04 |
| Liposomal Bupivacaine vs Perineural Adjuvants in Adductor Canalf and iPACK Blocks in Total Knee Arthroplasty Liposomal Bupivacaine, Bupivacaine, Clonidine, Epinephrine, Buprenorphine and Dexamethasone (BPV-CEBD) Combination - Knee Arthroplasty, Total | Phase 4 | Not yet recruiting | Wake Forest University Health Sciences | 90 | 2027-02-01 | 2026-08-25 |
| MBI for Pain and Sleep in Adolescents and Young Adults With Sickle Cell Disease Mindfulness-based intervention - Chronic Pain, Sickle Cell Disease | Not applicable | Not yet recruiting | University of Illinois at Chicago | 48 | 2027-02-01 | 2026-09-21 |
Showing 20 of 9270. Sign in to see all of them.
Agnosia (2960) · Delirium (880) · Emergence Delirium (733) · Pain (722) · Pain, Postoperative (607) · Down Syndrome (432) · Intellectual Disability (373) · Memory Disorders (369) · Cognitive Dysfunction (348) · Stroke (338) · Aphasia (323) · Alzheimer Disease (316) · Dementia (297) · Consciousness Disorders (281) · Psychomotor Agitation (280)
Neurologic Manifestations (9228) · Nervous System Diseases (9207) · Pathological Conditions, Signs and Symptoms (8550) · Signs and Symptoms (8380) · Mental Disorders (3971) · Perceptual Disorders (3272) · Neurocognitive Disorders (2373) · Pathologic Processes (2262) · Central Nervous System Diseases (1595) · Brain Diseases (1528) · Confusion (1461) · Postoperative Complications (1456) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1144) · Communication Disorders (1085)
Dexmedetomidine (270) · Bupivacaine (186) · Saline Solution (182) · Sodium Chloride (154) · Transcranial Direct Current Stimulation (138) · Ketamine (116) · Acetaminophen (114) · Morphine (114) · Propofol (112) · Fentanyl (103) · Ropivacaine (99) · Lidocaine (97) · Control Groups (80) · Midazolam (76) · Transcranial Magnetic Stimulation (69)
Assistance Publique - Hôpitaux de Paris (77) · Riphah International University (72) · Massachusetts General Hospital (67) · Assiut University (62) · VA Office of Research and Development (52) · Ain Shams University (51) · Johns Hopkins University (49) · University Hospital, Toulouse (46) · Stanford University (45) · Tanta University (45) · University of California, Los Angeles (43) · Hospices Civils de Lyon (40) · Cairo University (39) · University of Pennsylvania (39) · Duke University (38)
United States (3086) · Turkey (Türkiye) (736) · France (666) · China (584) · Canada (508) · Egypt (348) · Italy (346) · United Kingdom (297) · Germany (278) · Spain (268) · South Korea (154) · Brazil (147) · Belgium (142) · Netherlands (142) · Pakistan (136)
Dong-Xin Wang, MD, PhD (20) · Claudia Spies, MD, Prof. (18) · Anna Taddio, PhD (11) · Walaa Y Elsabeeny, MD (10) · BioXcel MM, MD (8) · Jian-Xin Zhou, MD (8) · Nicolai Goettel, MD (8)
PMID 33238043, PMID 34196963, PMID 15670960, PMID 22900785, PMID 21712276, PMID 23992774, PMID 36114133, PMID 37460385, PMID 15114210, PMID 15082703, PMID 22323509, PMID 22565936, PMID 28576285, PMID 30737315, PMID 38036236, PMID 39498781, PMID 39800465, PMID 40681915, PMID 41533472, PMID 41961243, PMID 17452283, PMID 19745202, PMID 19954851, PMID 21197418, PMID 21462081, PMID 21780073, PMID 22032743, PMID 22305346, PMID 22762316, PMID 22820638, PMID 24574549, PMID 25535538, PMID 25701796, PMID 26827847, PMID 26848997, PMID 26890096, PMID 28973626, PMID 29017067, PMID 29550525, PMID 30113379, PMID 30354289, PMID 31344528, PMID 33279955, PMID 33395098, PMID 37535937, PMID 38363467, PMID 38671361, PMID 38954871, PMID 39108660, PMID 39383458
2025 (22), 2019 (21), 2016 (17), 2023 (17), 2017 (16), 2014 (9), 2009 (8), 2015 (8), 2018 (7), R01DC014708 (5), 2008 (4), R01AG055425 (4), R01DA008391 (4), U10CA180886 (4), 2004 (3)