5086 completed, 1401 unknown, 1398 recruiting, 589 terminated. 3746 Not applicable, 1710 Phase 2, 970 Phase 3, 902 Phase 1, 434 Phase 4.
Follow Neuromuscular Diseases: new trials by email Literature Review of Neuromuscular Diseases trials Research Report on Neuromuscular Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ketamine and Midazolam Infusions for CRPS: Feasibility Study Ketamine, Midazolam, Normal Saline - Complex Regional Pain Syndromes | Phase 2 | Withdrawn | Stanford University | 2099-01-01 | 2024-11-22 | |
| A Multiple Dose Study to Investigate Safety, Tolerability and Pharmacokinetics of TBN Tetramethylpyrazine nitrone (TBN) tablet / Placebo - Healthy | Phase 1 | Not yet recruiting | Guangzhou Magpie Pharmaceuticals Co., Ltd. | 16 | 2028-09-01 | 2026-09-11 |
| Evaluation of Donor-Derived B Cell Infusions in Patients With Amyotrophic Lateral Sclerosis (ALS) B cell infusion - ALS - Amyotrophic Lateral Sclerosis | Phase 1 | Not yet recruiting | Mark Poznansky | 10 | 2027-09-01 | 2026-09-24 |
| Feasibility and Preliminary Effects of an Asynchronous Microlearning Intervention on Fibromyalgia Knowledge Among Primary Health Care Workers Written Educational Material on Fibromyalgia, Asynchronous Microlearning Intervention on Fibromyalgia - Fibromyalgia, Fibromyalgia (FM) | Not applicable | Not yet recruiting | Instituto Neurociencia Del Dolor | 68 | 2027-06-01 | 2026-10-13 |
| Hypersound Treatment for Chronic Neuropathic and Radicular Pain Hypersound RF-PNS system, Sham Hypersound - Chronic Neuropathic Pain, Radiculopathy | Not applicable | Not yet recruiting | Hypersound Medical Inc | 71 | 2027-06-01 | 2026-09-21 |
| Phase I/IIa Trial of scAAV1.tMCK.NTF3 for Treatment of CMT1A scAAV1.tMCK.NTF3 - Charcot-Marie-Tooth Neuropathy Type 1A | Phase 1 / Phase 2 | Withdrawn | Nationwide Children's Hospital | 2027-04-01 | 2026-07-29 | |
| Safety and Efficacy Study on AFA-281 for the Treatment of Low Back Pain AFA-281 - Lumbosacral Radiculopathy | Phase 2 | Not yet recruiting | Afasci Inc | 408 | 2027-04-01 | 2025-06-26 |
| Quantification of Change in MG Disease Activity in Individuals With Generalized Myasthenia Gravis (gMG) After Administration of VYVGART® or VYVGART Hytrulo® Using BioDigit MG Myasthenia Gravis Generalized | Not yet recruiting | BioSensics | 25 | 2027-03-15 | 2026-10-13 | |
| Graded Motor Imagery in Carpal Tunnel Syndrome Graded Motor Imagery (GMI), Progressive Neurodynamic Exercise, Nighttime Resting Splint - Carpal Tunnel Syndrome (CTS) | Not applicable | Not yet recruiting | Artvin Coruh University | 46 | 2027-03-01 | 2026-09-02 |
| Safety Study of XT-150 in Participants With ALS XT-150 - Amyotrophic Lateral Sclerosis (ALS) | Phase 1 | Not yet recruiting | Xalud Therapeutics, Inc. | 8 | 2027-03-01 | 2026-07-29 |
| A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus) Glycerol Tributyrate - MELAS Syndrome, Lebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus) | Phase 1 / Phase 2 | Not yet recruiting | George Washington University | 24 | 2027-03-01 | 2026-10-05 |
| Teams Engaged in Accessible Mental Health Interventions for Lupus Erythematosus and Dermatomyositis Stress TEAM-LEADS - Lupus, Dermatomyositis, Juvenile | Not applicable | Not yet recruiting | Duke University | 25 | 2027-02-01 | 2026-05-27 |
| Corticosteroid Lumbar Epidural Analgesia for Radicular Pain 2 SP-102, Placebo, Dexamethasone Sodium Phosphate 10 MG/ML - Lumbosacral Radicular Pain | Phase 3 | Not yet recruiting | Semnur Pharmaceuticals, Inc. | 755 | 2027-02-01 | 2026-09-09 |
| Effects of Hydrogen-rich Water Consumption on Transient Fatigue During an Official Football Match. Hydrogen-Rich Water (HRW), Placebo Water - Exercise-Induced Fatigue, Football Performance | Not applicable | Not yet recruiting | Palacky University | 30 | 2027-01-20 | 2026-10-08 |
| Randomized Evaluation of Lumbar Injection Effectiveness and Function Triojection® System, Selective Nerve Root Block (SNRB) - Lumbar Radiculopathy, Lumbar Disc Herniation | Not applicable | Not yet recruiting | SpinaFX Medical Inc. | 300 | 2027-01-15 | 2026-10-07 |
| Comparison of Efficacy of Caudal Versus Transforaminal Epidural Steroid Injections in Unilateral S1 Nerve Root Pain: A Randomized Controlled Trial Caudal Epidural Steroid Injection (CEI), Transforaminal Epidural Steroid Injection (TFI) - Unilateral S1 Nerve Root Pain | Not applicable | Not yet recruiting | University of Health Sciences Lahore | 120 | 2027-01-05 | 2026-10-16 |
| BreEStim in Managing Neuropathic Pain After Spinal Cord Injury (SCI) Active BreEStim Treatment, Sham BreEStim Treatment, The TENS Treatment - Pain Management | Not applicable | Not yet recruiting | The University of Texas Health Science Center, Houston | 66 | 2027-01-04 | 2026-10-14 |
| AI and Computer Vision-Assisted Telerehabilitation in Fibromyalgia: The FibroIA 2.0 Trial AI Combined (mobility and resistance training), AI mobility - Fibromyalgia, Fibromyalgia (FM) | Not applicable | Not yet recruiting | Instituto Neurociencia Del Dolor | 66 | 2027-01-04 | 2026-07-01 |
| Combination of Avutometinib and Defactinib for Treatment of Relapsed, Refractory, Metastatic, or Unresectable Malignant Peripheral Nerve Sheath Tumor avutometinib capsule + defactinib tablet - MPNST (Malignant Peripheral Nerve Sheath Tumor) | Phase 2 | Not yet recruiting | Girish Dhall, MD | 23 | 2027-01-01 | 2026-08-04 |
| Treatment of Fibromyalgia and PTSD With Live and Inactive Vagus Nerve Stimulation With PEPC tAN plus PEPC, sham plus PEPC - Fibromyalgia (FM), Posttraumatic Stress Disorder (PTSD) | Not applicable | Not yet recruiting | VA Office of Research and Development | 180 | 2027-01-01 | 2026-09-29 |
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