194 completed, 89 unknown, 32 recruiting, 14 terminated. 93 Not applicable, 64 Phase 4, 47 Phase 3, 28 Phase 2.
Follow Angina, Unstable: new trials by email Literature Review of Angina, Unstable trials Research Report on Angina, Unstable
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Rapid or Ultra-rapid Diagnosis of Myocardial Infarction Using High-Sensitivity Cardiac Troponin on Hospital Presentation 0/3-hour high-sensitivity cardiac troponin algorithm, 0/1-hour high-sensitivity cardiac troponin algorithm - Coronary Syndrome, Acute, Myocardial Infarction | Not applicable | Not yet recruiting | Herlev and Gentofte Hospital | 28000 | 2026-09-01 | 2026-08-06 |
| Early Triple Lipid-Lowering Therapy With Bempedoic Acid After Acute Coronary Syndrome bempedoic acid, Ezetimibe, High-Intensity Statin Therapy - Acute Coronary Syndromes, Dyslipidemia | Phase 4 | Recruiting | Taipei Medical University Hospital | 400 | 2026-08-26 | 2026-09-17 |
| Analysis of Life-threatening ARrhythMias After Acute Coronary Syndrome Acute Coronary Syndromes (ACS), Ventricular Tachycardia (VT) | Recruiting | Catharina Ziekenhuis Eindhoven | 2775 | 2026-07-14 | 2026-10-13 | |
| Early Single Antiplatelet Therapy After IVUS-Guided PCI in Acute Coronary Syndrome Early P2Y12 Inhibitor Monotherapy, Standard Dual Antiplatelet Therapy - Acute Coronary Syndromes, STEMI | Phase 4 | Not yet recruiting | Gyeongsang National University Hospital | 1900 | 2026-07-01 | 2026-07-06 |
| Invasive Evaluation and Phenotype-Guided Treatment of ANOCA in Women Invasive Coronary Functional and Morphological Assessment, Pharmacological treatment will be individualized according to the invasive coronary phenotype identified. Treatment may include antianginal therapy, vasodilator therapy, endothelial function-targeted - ANOCA - Angina With Non-obstructive Coronary Arteries, Coronary Microvascular Dysfunction (CMD) | Not applicable | Not yet recruiting | Hospital de Clínicas Dr. Manuel Quintela | 50 | 2026-05-15 | 2026-05-18 |
| Clinical Characteristics, Frailty, and Prognostic Predictors in Patients Aged 75 and Older With Acute Coronary Syndrome Percutaneous Coronary Intervention (PCI), Conservative Medical Therapy - ST Elevation (STEMI) Myocardial Infarction, Non ST Elevation Myocardial Infarction (NSTEMI) | Recruiting | Clinical Center Niš | 550 | 2026-05-13 | 2026-05-15 | |
| Prospective Lifespan Cohort of Myocardial Infarction Acute Myocardial Infarction (AMI), Stable Angina | Not yet recruiting | Fujian Provincial Hospital | 6000 | 2026-04-10 | 2026-03-25 | |
| Safety and Effectiveness of the Crystalline Sirolimus-Eluting Device in Patients With Coronary Artery Disease Coronary Arterial Disease (CAD), NSTEMI - Non-ST Segment Elevation Myocardial Infarction (MI) | Recruiting | Fundación Interhospitalaria para la Investigación Cardiovascular FIC | 1118 | 2026-01-05 | 2026-03-03 | |
| Advanced NanoTherapies Dual-API DCB to Treat De-Novo and ISR Lesions in Patients With Symptomatic Coronary Artery Disease SirPlux Duo™ Dual API-Coated PTCA Balloon Catheter - Angina (Stable), CAD - Coronary Artery Disease | Not applicable | Recruiting | Advanced NanoTherapies | 30 | 2025-12-15 | 2026-01-27 |
| Validation of the MedHub AutocathFFR Software Device for Non-Invasive Fractional Flow Reserve (FFR) MedHub AutocathFFR - Coronary Artery Disease, Stable Angina | Completed | Medhub Ltd. | 277 | 2025-11-04 | 2026-08-13 | |
| Breaking Fasts Ahead of Cardiac Caths Non-Fasting, Fasting - Stable Angina (SA), Unstable Angina (UA) | Not applicable | Recruiting | University of South Florida | 400 | 2025-10-13 | 2025-12-16 |
| Occurrence of Severe Cardiac Rhythm and Conduction Disturbances in Emergency Department Patients With Non-ST Elevation Acute Coronary Syndrome Acute Coronary Syndrome Without ST Elevation on Electrocardiogram, Acute Coronary Syndromes (ACS) | Not yet recruiting | University Hospital, Strasbourg, France | 500 | 2025-09-01 | 2025-08-08 | |
| Oregano and Basil Leaves and Coronary Artery Disease Control (Standard treatment), Higher polyphenol intake by consumption of oregano and basil - Acute Coronary Syndromes, Unstable Angina (UA) | Not applicable | Recruiting | Shahid Beheshti University of Medical Sciences | 70 | 2025-09-01 | 2026-06-16 |
| A Multi-center, Real-World Clinical Trial of caIMR on Two Specific Kinds of Patients. caIMR - Coronary Microvascular Dysfunction (CMD), Stable Angina Pectoris | Not yet recruiting | Ge Junbo | 508 | 2025-07-01 | 2025-04-27 | |
| Scientific Rationale and Design for a Prospective Study to Codify Coronary Lesions Based on Fluid Mechanics and Acoustic Mechanisms Unstable Angina (UA) | Not yet recruiting | Tan Tao University, School of Medicine | 100 | 2025-04-20 | 2025-04-17 | |
| Comparison of Conventional and Non-Conventional CRF and Their Association With Acute Coronary Syndrome Conventional Risk Factor Assessment, Non-Conventional Risk Factor - Coronary Syndrome | Active not recruiting | Superior University | 222 | 2025-03-17 | 2025-07-03 | |
| A MAajor RAdiation-based PCI Study in STEMI and NSTEMI Non Complex PCI, Complex PCI - Myocardial Infarction (MI), Radiation Toxicity | Active not recruiting | Centre Cardiologique du Nord | 15630 | 2025-03-01 | 2026-08-21 | |
| The Impact of Vericiguat on Microvascular Function in Patients With Documented Vasospastic Angina Pectoris Vericiguat - Vasospastic Angina | Phase 2 | Completed | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 57 | 2025-02-10 | 2026-07-29 |
| Cardioneuroablation for Variant Angina cardioneuroablation - Variant Angina | Not applicable | Active not recruiting | Zhibing Lu | 16 | 2025-02-07 | 2025-11-25 |
| FAPO-2: Cardiac Patient Monitoring Tool for Clinical Observation and Arrhythmia Detection Smartwatch - all data, Portable holter system, Telemonitoring - Heart Diseases, Atrial Fibrillation (AF) | Not applicable | Recruiting | University of Sao Paulo | 520 | 2025-02-07 | 2025-09-15 |
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Acute Coronary Syndrome (111) · Myocardial Infarction (110) · Angina, Stable (93) · Coronary Artery Disease (85) · Non-ST Elevated Myocardial Infarction (79) · ST Elevation Myocardial Infarction (51) · Myocardial Ischemia (37) · Angina Pectoris (36) · Angina Pectoris, Variant (34) · Coronary Disease (34) · Cardiovascular Diseases (23) · Chest Pain (21) · Atherosclerosis (17) · Coronary Stenosis (15)
Neurologic Manifestations (360) · Pathological Conditions, Signs and Symptoms (360) · Pain (359) · Signs and Symptoms (359) · Vascular Diseases (358) · Heart Diseases (347) · Chest Pain (339) · Cardiovascular Diseases (337) · Angina Pectoris (324) · Myocardial Ischemia (323) · Pathologic Processes (199) · Infarction (179) · Ischemia (179) · Necrosis (179) · Arteriosclerosis (101)
Ticagrelor (14) · Clopidogrel (13) · Percutaneous Coronary Intervention (13) · Atorvastatin (11) · Aspirin (9) · Enoxaparin (6) · Heparin (5) · Hydroxymethylglutaryl-CoA Reductase Inhibitors (5) · Rivaroxaban (5) · Abciximab (4) · Amlodipine (4) · Drug-Eluting Stents (4) · Lipid Regulating Agents (4) · Prasugrel Hydrochloride (4) · Morphine (3)
University College, London (12) · Collegium Medicum w Bydgoszczy (6) · Massachusetts General Hospital (6) · Seoul National University Hospital (6) · Samsung Medical Center (5) · Assistance Publique - Hôpitaux de Paris (4) · Foundation of Cardiovascular Research and Education Enschede (4) · Jun Li (4) · National Heart, Lung, and Blood Institute (NHLBI) (4) · AstraZeneca (3) · CID - Carbostent & Implantable Devices (3) · Catharina Ziekenhuis Eindhoven (3) · Copenhagen University Hospital, Rigshospitalet (3) · Karolinska Institutet (3) · Korea Otsuka Pharmaceutical Co., Ltd. (3)
United States (62) · South Korea (39) · China (35) · Italy (35) · Netherlands (33) · United Kingdom (26) · Canada (25) · France (23) · Germany (22) · Belgium (21) · Poland (21) · Spain (18) · Brazil (13) · Russia (13) · Sweden (13)
Jun Li, MD (4) · Yong Huo, MD (4) · Bon-Kwon Koo, MD, PhD (3) · Christian Mueller, MD (3) · Jacek Kubica, MD., PhD. (3) · Alan S Maisel, MD (2) · Florence Leclercq, PU PH (2) · Florim Cuculi, MD (2) · Javier Escaned, MD, PhD (2) · Jean-Claude Tardif, MD (2) · Jeffrey M Levsky, MD, PhD (2) · Katriona Brooksbank, PhD (2) · Linda B Haramati, MD, MS (2)
PMID 22536282, PMID 23762142, PMID 27777598, PMID 35641327, PMID 37619976, PMID 37745109, PMID 23737852, PMID 25254054, PMID 22483327, PMID 28923845, PMID 31242362, PMID 31535314, PMID 32654558, PMID 33766254, PMID 34237166, PMID 34251454, PMID 34649504, PMID 34717627, PMID 35589164, PMID 37675090, PMID 38598970, PMID 39959922, PMID 40687396, PMID 10987628, PMID 11239408, PMID 12196333, PMID 12493162, PMID 12595860, PMID 14670830, PMID 14990846, PMID 15238590, PMID 15914483, PMID 16304073, PMID 16357399, PMID 16432071, PMID 16507234, PMID 16507235, PMID 16533938, PMID 16537663, PMID 16562568, PMID 16650886, PMID 16702455, PMID 17010793, PMID 17060377, PMID 17065671, PMID 17075011, PMID 17111198, PMID 17124018, PMID 17131076, PMID 17145253
2016 (2), 1RC2HL101458-01 (1), 2005 (1), 2014 (1), 2018 (1), 2019 (1), K23AT009715 (1), K23HL004444 (1), R01HL038702 (1), R01HL050839 (1), R01HL076808 (1), R01HL080053 (1), R01HL085328 (1), U01HL077821 (1), U01HL077822 (1)