243 trials newly registered, first posted 2026-10-21, by therapeutic area, largest first. Existing trials that posted results or changed status in the past seven days are under their own tabs; routine edits to existing records (sites, contacts, enrollment numbers) are not listed.
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
Symptoms and General Pathology 59 Nervous System Diseases 32 Cancers and Other Neoplasms 31 Heart and Blood Diseases 23 Behaviors and Mental Disorders 21 Respiratory Tract (Lung and Bronchial) Diseases 20 Urinary Tract, Sexual Organs, and Pregnancy Conditions 18 Blood and Lymph Conditions 15 Digestive System Diseases 14 Nutritional and Metabolic Diseases 14 Gland and Hormone Related Diseases 12 Infections 12 Diseases and Abnormalities at or Before Birth 11 Immune System Diseases 11 Wounds and Injuries 8 Skin and Connective Tissue Diseases 7 Mouth and Tooth Diseases 6 Muscle, Bone, and Cartilage Diseases 6 Eye Diseases 3 Ear, Nose, and Throat Diseases 2 Substance Related Disorders 2 Other 86 Results posted this week 73 Status changes this week 723 All areas
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of HS-10382 Versus Investigator-selected TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CP HS-10382, Imatinib, Dasatinib - Chronic Myeloid Leukemia | Phase 3 | Not yet recruiting | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 408 | 2026-12-01 | 2026-10-21 |
| A Clinical Study of AHB-121 in Healthy Participants and Chronic Hepatitis B (CHB) Participants AHB-121, Placebo - Chronic Hepatitis B Virus | Phase 1 | Not yet recruiting | Ausper Biopharma Co., Ltd. | 110 | 2026-10-28 | 2026-10-21 |
| A Study of the Safety and Efficacy of Prime Editing (PM647a) in Participants With Alpha-1 Antitrypsin Deficiency PM647a - Alpha-1 Antitrypsin Deficiency, Alpha-1 Antitrypsin Deficiency-associated Lung Disease | Phase 1 / Phase 2 | Not yet recruiting | Prime Medicine, Inc. | 54 | 2026-10-01 | 2026-10-21 |
| Oral Care Program for Mouth Side Effects During Head and Neck Radiation Therapy ORAL CARE PRODUCT KIT - Head and Neck Cancer (H&N), Oral Mucositis (Ulcerative) Due to Radiation | Not applicable | Not yet recruiting | UNCANCER LLC | 50 | 2026-11-01 | 2026-10-21 |
| Testing the Timing and Application of Virtual Reality Distraction During Knee Injections in a VA Pain Clinic Immersive Virtual Reality - Pain Management, Injection Pain Prevention | Not applicable | Not yet recruiting | Atlanta VA Medical Center | 45 | 2026-10-01 | 2026-10-21 |
| Chinese Overweight/Obesity Cohort: Metabolic & Comorbidity Risks No intervention; observational assessment only - Obesity & Overweight, Diabetes Mellitus, Type 2 | Not yet recruiting | Shanxi Bethune Hospital | 25974 | 2026-11-01 | 2026-10-21 | |
| A Fifth Proof-of-Concept Study to Evaluate the Efficacy of NOBO, a Novel Postbiotic, in Controlling Axillary Odor in Healthy Adults NOBO postbiotic, Placebo - Body Odor | Not applicable | Active not recruiting | Kingdom | 16 | 2026-10-11 | 2026-10-21 |
| A Study to Learn About the Study Medicine Abrocitinib in People With Severe Atopic Dermatitis Who Have Switched From Other Therapies abrocitinib - Dermatitis, Atopic | Not yet recruiting | Pfizer | 120 | 2026-10-01 | 2026-10-21 | |
| Randomized Interventional Clinical Trial on the Prevention of Atrial Fibrillation Using Colchicine, Amiodarone And a Posterior Pericardiotomy. Colchicine, Amiodarone, Posterior pericardiotomy - Atrial Fibrillation (AF) | Phase 3 | Not yet recruiting | Elsan | 636 | 2027-01-01 | 2026-10-21 |
| Exercise, Mediterranean Diet and Inflammation in Heart Failure Structured exercise training program, Mediterranean diet counseling, Standard heart failure management - Heart Failure, Heart Failure Preserved Ejection Fraction | Not applicable | Not yet recruiting | Hospital Severo Ochoa | 214 | 2026-11-01 | 2026-10-21 |
| PATH to Reducing Burnout Among Peers Who Deliver Overdose Prevention Services (R33 Phase Clinical Trial) PATH (Peer Advanced Training for total Health) - Burnout, Secondary Trauma | Not applicable | Enrolling by invitation | Chestnut Health Systems | 200 | 2026-10-12 | 2026-10-21 |
| VATS or Intrapleural Enzymatic Therapy for Patients With Empyema. VATS group, IET - Empyema, Pleural, Pleural Infections | Phase 4 | Not yet recruiting | Amsterdam UMC | 164 | 2026-10-01 | 2026-10-21 |
| Acupuncture for Symptom Burden and Quality of Life in Patients With End-Stage Kidney Disease Acupuncture, Sham Acupuncture - End Stage Kidney Disease (ESKD) | Not applicable | Not yet recruiting | University General Hospital of Heraklion | 160 | 2026-12-01 | 2026-10-21 |
| Nerve Block Resolution Time Display and Pain Complaints Physical display - Postoperative Pain, Rebound Pain | Not applicable | Not yet recruiting | Medical University of South Carolina | 128 | 2026-10-01 | 2026-10-21 |
| Effectiveness of a Music Therapy Intervention in Cancer Patients Undergoing Active Treatment at the Jaén University Hospital: a Non-randomized Controlled Trial. Music Therapy - Anxiety, Signs and Symptoms | Not applicable | Completed | University of Jaén | 120 | 2025-04-01 | 2026-10-21 |
| Acupressure as Complementary Analgesia in Shock Wave Lithotripsy Acupressure, Sham Acupressure - Acupressure, Urinary Calculi | Not applicable | Recruiting | Medipol University | 105 | 2026-10-10 | 2026-10-21 |
| Urinary Catheterization Versus No Catheterization in Laparoscopic Total Extraperitoneal Inguinal Hernia Repair Routine Urinary Catheterization, No Routine Urinary Catheterization - Inguinal Hernias | Not applicable | Active not recruiting | Ugur Duman | 100 | 2026-03-01 | 2026-10-21 |
| MRD and Imaging Guided Adaptive Neoadjuvant Therapy for Resectable NSCLC PD-1 inhibitor, Carboplatin, Nab-paclitaxel - Non-Small Cell Lung Cancer (NSCLC) | Phase 2 | Not yet recruiting | Peking University People's Hospital | 100 | 2026-11-01 | 2026-10-21 |
| AI-SC Multi-center Study evaluate the alignment between AI-SC recommendations and LT-SC decisions, Multi AI-SC model - Liver Cirrhosis | Active not recruiting | University Health Network, Toronto | 1000 | 2026-04-01 | 2026-10-21 | |
| AI-based Algorithm Development for Improved Diagnostics in the Intensive Care and Acute Stroke Setting Using Electroencephalography Hemorrhagic Stroke, Intracerebral, Subarachnoid Haemorrhage (SAH) | Recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 825 | 2026-03-26 | 2026-10-21 | |
| Gamified Interactive Narrative (REPRO-QUEST) on Sexual Health Literacy and Sexually Transmitted Infection Prevention Behaviors REPRO-QUEST Interactive Narrative, Educational Booklet - Sexual Health, Sexually Transmitted Infection (STI) | Not applicable | Completed | Karamanoğlu Mehmetbey University | 82 | 2026-04-04 | 2026-10-21 |
| COPD Prevalence and Risk Factors Among Saudi Adults Over 18 in Taif Chronic Obstructive Pulmonary Disease (COPD) | Completed | Taif University | 777 | 2024-10-24 | 2026-10-21 | |
| New Treatment in Melasma Tranexamic Acid - topical, Microneedling with Topical Tranexamic acid, Modified Kligman's Formula - Female, With | Not applicable | Not yet recruiting | Sohag University | 75 | 2026-10-18 | 2026-10-21 |
| Dose-sparing Balanced Propofol Sedation in Colonoscopy Standard-dose balanced propofol analgosedation, Dose-sparing balanced propofol analgosedation - Colonoscopy, Sedation and Analgesia | Not applicable | Completed | University of Split, School of Medicine | 76 | 2022-06-05 | 2026-10-21 |
| Reiki After Bariatric Surgery reiki, Sham Reiki - Nausea and Vomitting, Distension; Bowel | Not applicable | Completed | TC Erciyes University | 75 | 2025-11-01 | 2026-10-21 |
| Effects of Respiratory Muscle Strengthening and Diaphragmatic Breathing on Shoulder Pain and Disability shoulder rehabilitation, respiratory muscle strengthening exercises and diaphragmatic breathing exercises - Shoulder Pain, Sleep Quality | Not applicable | Recruiting | Zonguldak Bulent Ecevit University | 70 | 2025-11-25 | 2026-10-21 |
| Telerehabilitation-Supported Exercise in Women With Lipedema Telerehabilitation-Supported Exercise, Home Exercise Program - Lipedema | Not applicable | Not yet recruiting | Istanbul University | 66 | 2026-10-19 | 2026-10-21 |
| EFFECT OF ABDOMINAL MASSAGE TRAINING PROVIDED TO CAREGIVERS ON CONSTIPATION MANAGEMENT Caregiver Training in Abdominal Massage - Constipation | Not applicable | Recruiting | HAMİYET KIZIL | 62 | 2026-09-09 | 2026-10-21 |
| Measured Versus Hemoglobin-Calculated Postpartum Blood Loss in Waterbirth Water immersion during labor and birth - Postpartum Hemorrhage, Waterbirth | Not yet recruiting | University of Campania Luigi Vanvitelli | 600 | 2027-04-01 | 2026-10-21 | |
| EFFECT OF COMBINED VIRTUAL REALITY-GUIDED BREATHING AND AEROBIC TRAINING ON VENTILATORY FUNCTION IN PATIENTS WITH COPD VR-Based Pulmonary Rehabilitation Group, Conventional Pulmonary Rehabilitation Group - Chronic Obstructive Lung Disease | Not applicable | Not yet recruiting | Cairo University | 60 | 2026-11-01 | 2026-10-21 |
| Photobiomodulation After Nonsurgical Root Canal Treatment Adjunctive Photobiomodulation, Sham Photobiomodulation - Symptomatic Apical Periodontitis, Postoperative Pain | Not applicable | Not yet recruiting | University of Minnesota | 60 | 2026-10-19 | 2026-10-21 |
| Deep Repetitive Transcranial Magnetic Stimulation in the Treatment of Tinnitus DeepTms - Tinnitus, Tinnitus, Bilateral | Not applicable | Recruiting | University of Regensburg | 60 | 2026-09-19 | 2026-10-21 |
| Postsurgical Pain and Opioid Use in Older Adults: Effects of Mild Cognitive Impairment Mild Cognitive Impairment (MCI), Opioid Use | Not yet recruiting | Miklos Kertai | 552 | 2027-01-01 | 2026-10-21 | |
| Implementation of Shoulder School in Albania Shoulder school, Standard Care (in control arm) - Rotator Cuff Related Shoulder Pain | Not applicable | Not yet recruiting | University of Valladolid | 50 | 2026-11-01 | 2026-10-21 |
| reALIGNing Circadian Rhythm and Promoting Sleep in the Intensive Care Unit Sleep chronobundle, Control - Sleep, Circadian Dysregulation | Early Phase 1 | Not yet recruiting | University of Alberta | 50 | 2026-11-30 | 2026-10-21 |
| HUGO-SLEEVE: Evaluating the Feasibility of Robotic Sleeve Gastrectomy With a New Platform Sleeve Gastrectomy using Hugo RAS platform - Obesity (BMI > 35), Obesity (BMI > 35) and Diabetes Mellitus | Not applicable | Recruiting | Universitätsklinikum Hamburg-Eppendorf | 50 | 2026-06-04 | 2026-10-21 |
| Study of Grape Consumption in Adaptation to Seasonal Photoperiod Freeze-Dried Grape Powder, Plain Low-Fat Yogurt, Mediterranean-Style Dietary Guidance - Metabolic Dysfunction-Associated Steatotic Liver Disease, Overweight | Not applicable | Active not recruiting | University Rovira i Virgili | 46 | 2026-09-28 | 2026-10-21 |
| Buzzy Bee for Pain and Anxiety Control During Pediatric Dental Local Anesthesia Intervention A: Buzzy® Bee-Assisted Local Anesthesia, Intervention B: Conventional Local Anesthesia Technique - Anesthesia, Anxiety | Not applicable | Recruiting | Tanta University | 40 | 2025-08-01 | 2026-10-21 |
| Functional Electrical Stimulation Combined With Exercise for Rotator Cuff-Related Shoulder Pain in Older Adults Functional electrical stimulation, Sham Functional Electrical Stimulation, Progressive Resistance Training - Rotator Cuff Disease, Subacromial Pain Syndrome | Not applicable | Recruiting | Lisa Griffin | 40 | 2025-10-01 | 2026-10-21 |
| Effects of Myofascial Release on Postural Balance and Cervical Muscle Function in Benign Paroxysmal Positional Vertigo Home-Based Balance Exercise Program, Myofascial Release Therapy - Benign Paroxysmal Positional Vertigo | Not applicable | Completed | Karabuk University | 40 | 2021-09-01 | 2026-10-21 |
| Long Term Outcome After Use of Vacuum-induced Tamponade for Postpartum Hemorrhage Postpartum Hemorrhage, Treatment Outcome | Recruiting | University of Zurich | 380 | 2026-10-01 | 2026-10-21 | |
| Cannabidiol in Opioid Use Disorder and Chronic Pain With Buprenorphine 400 mg Cannabidiol, 800 mg Cannabidiol, 1200 mg Cannabidiol - Chronic Pain, Opioid Use Disorder | Early Phase 1 | Recruiting | Yale University | 34 | 2021-12-08 | 2026-10-21 |
| Tacabrutideg and Sonrotoclax, With Response-Guided Obinutuzumab, for the Treatment of Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) Tacabrutideg, Sonrotoclax, Obinutuzumab - Chronic Lymphocytic Leukemia, Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma | Phase 2 | Not yet recruiting | Fred Hutchinson Cancer Center | 30 | 2027-01-01 | 2026-10-21 |
| Recurrence of Extremity Joint Contracture After Z-Plasty Versus Full-Thickness Skin Graft Z-Plasty, Full-Thickness Skin Graft - Joint Contracture, Contracture | Not yet recruiting | Universitas Sebelas Maret | 300 | 2026-10-13 | 2026-10-21 | |
| Safety of Anticoagulation Therapy in Cirrhotic Patients With PVT and Severe Thrombocytopenia Anticoagulation Therapy - Thrombocytopenia Related to Chronic Liver Disease, Anticoagulation Treatment | Completed | Qilu Hospital of Shandong University | 304 | 2025-09-01 | 2026-10-21 | |
| 68Ga-XMFH01 PET/Fluorescence Imaging in Prostate Cancer 68Ga-XMFH01 PET/CT - Prostate Cancer (Diagnosis), ACP3 | Not applicable | Recruiting | The First Affiliated Hospital of Xiamen University | 25 | 2026-10-21 | 2026-10-21 |
| Perfusion Efficiency-Guided MAP De-escalation in Elderly Septic Shock Ascending MAP titration sequence, Descending MAP titration sequence - Sepsis | Not applicable | Not yet recruiting | Peking Union Medical College Hospital | 24 | 2026-11-01 | 2026-10-21 |
| Hypoglycemia Risk Assessment in Elderly and Senile Female Patients With Type 2 Diabetes Mellitus Comprehensive Geriatric Assessment, Sarcopenia assessment, Laboratory assessment - Type 2 Diabetes Mellitus, Hypoglycemia | Completed | Samara State Medical University | 200 | 2020-01-01 | 2026-10-21 | |
| Circuit Breathing Exercise on Smoking Cessation Among Youth E-Cigarette Users Circuit breathing, Diaphragmatic Breathing, Normal Breathing Condition - E Cigarette Use | Not applicable | Recruiting | Chulalongkorn University | 20 | 2026-08-15 | 2026-10-21 |
| Manual Acupuncture for Intradialytic Fatigue in CKD Patients Manual Acupuncture, Sham Acupuncture - Intradialytic Fatigue, Chronic Kidney Disease | Not applicable | Not yet recruiting | Universitas Indonesia | 19 | 2026-10-01 | 2026-10-21 |
| Factors Influencing Outcomes in ECMO and Impella Patients: Metabolic and Thyroid Hormone Dynamics Cardiogenic Shock, Euthyroid Sick Syndrome | Recruiting | Gottsegen National Cardiovascular Institute | 160 | 2026-08-17 | 2026-10-21 | |
| Efficacy and Safety of Modafinil to Treat Fatigue in People With Mitochondrial Disease. Modafinil (Placebo) - Mitochondrial Disease | Phase 3 | Not yet recruiting | Kenneth Myers, MD | 15 | 2026-12-01 | 2026-10-21 |
| Whole-Body Point-of-Care Ultrasound in Older Adults Presenting to the Emergency Department After a Fall Whole-body point-of-care ultrasound (POCUS) - Accidental Falls, Aged | Recruiting | Kocaeli City Hospital | 105 | 2026-10-12 | 2026-10-21 | |
| Clinical, Functional, and Therapeutic Characterization of Women With Urinary Incontinence and Analysis of Factors Associated With Treatment Response Artificial intelligence clinical decision support model - Urinary Incontinence (UI) | Not yet recruiting | Javier Pereira | 80 | 2026-12-01 | 2026-10-21 | |
| Deep Brain Stimulation Guided by Brain Mapping to Treat Cognitive Impairment Abbott St Jude Medical Infinity™ - Mild Cognitive Impairment (MCI), Mild Cognitive Impairment (MCI) Amnestic | Not applicable | Not yet recruiting | University of Texas Southwestern Medical Center | 6 | 2026-11-01 | 2026-10-21 |
| Enteral Feeding in Mechanically Ventilated Children Critical Illness, Mechanical Ventilation Complication | Not yet recruiting | Assiut University | 60 | 2026-10-26 | 2026-10-21 | |
| Dexmedetomidine for Refractory Pain in Palliative Cancer Patients Cancer, Palliative Care, Patient Care | Recruiting | St. Olavs Hospital | 30 | 2026-04-10 | 2026-10-21 | |
| Real-World Use of Tarlatamab in Chinese Patients With Small-Cell Lung Cancer Tarlatamab - Extensive-Stage Small Cell Lung Cancer | Active not recruiting | Ruijin Hospital | 26 | 2026-08-03 | 2026-10-21 | |
| Upper Airway Morphology and Physiology During Graded Positive Pressure and Nasal High Flow: An MRI Study Nasal High Flow, Continuous Positive Airway Pressure - Chronic Obstructive Pulmonary Disease (COPD) | Not yet recruiting | Klinikum Dortmund Wirbelsäulenchirurgie | 20 | 2026-10-01 | 2026-10-21 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Sleep MAPP in the Polytrauma/TBI System of Care Sleep MAPP Care Pathway - Insomnia Disorder, Mild Traumatic Brain Injury | Not applicable | Not yet recruiting | VA Office of Research and Development | 900 | 2027-01-01 | 2026-10-21 |
| Long-Term Safety and Tolerability of Nizubaglustat in Participants With Rare Lysosomal Disorders AZ-3102 - Niemann-Pick Disease Type C, GM2 Gangliosidosis | Phase 2 / Phase 3 | Not yet recruiting | Azafaros B.V. | 218 | 2026-12-10 | 2026-10-21 |
| Testing the Timing and Application of Virtual Reality Distraction During Knee Injections in a VA Pain Clinic Immersive Virtual Reality - Pain Management, Injection Pain Prevention | Not applicable | Not yet recruiting | Atlanta VA Medical Center | 45 | 2026-10-01 | 2026-10-21 |
| Chinese Overweight/Obesity Cohort: Metabolic & Comorbidity Risks No intervention; observational assessment only - Obesity & Overweight, Diabetes Mellitus, Type 2 | Not yet recruiting | Shanxi Bethune Hospital | 25974 | 2026-11-01 | 2026-10-21 | |
| A Study to Learn More About Friedrich's Ataxia in People Living in the Gulf Cooperation Council (GCC) Region of the World Friedreich's Ataxia | Not yet recruiting | Biogen | 40 | 2026-10-15 | 2026-10-21 | |
| Single-center, Open-label Study: Immunogenicity and Safety Observation After Vaccination With ACYW135 Meningococcal Polysaccharide Vaccine in Junior High School Students Aged 13-15 Years MPSV-ACYW - Meningococcal Disease; Meningococcal Meningitis | Phase 4 | Not yet recruiting | Zhejiang Provincial Center for Disease Control and Prevention | 200 | 2026-10-20 | 2026-10-21 |
| Optical Coherence Tomography-Assisted Strategy for Interventional Management of Symptomatic Carotid Stenosis (OASIS-C) OCT guided endovascular treatment - Carotid Stenosis | Not applicable | Not yet recruiting | Beijing Tiantan Hospital | 100 | 2026-11-01 | 2026-10-21 |
| Prevalence of Obstructive Sleep Apnea in HHT and HHT-specific Challenges in OSA-therapy - a Retrospective Cohort Study Hereditary Hemorrhagic Telangiectasia (HHT), Obstructive Sleep Apnea (OSA) | Not yet recruiting | University Hospital, Essen | 1000 | 2026-10-01 | 2026-10-21 | |
| AI-based Algorithm Development for Improved Diagnostics in the Intensive Care and Acute Stroke Setting Using Electroencephalography Hemorrhagic Stroke, Intracerebral, Subarachnoid Haemorrhage (SAH) | Recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 825 | 2026-03-26 | 2026-10-21 | |
| Dose-sparing Balanced Propofol Sedation in Colonoscopy Standard-dose balanced propofol analgosedation, Dose-sparing balanced propofol analgosedation - Colonoscopy, Sedation and Analgesia | Not applicable | Completed | University of Split, School of Medicine | 76 | 2022-06-05 | 2026-10-21 |
| Effects of Respiratory Muscle Strengthening and Diaphragmatic Breathing on Shoulder Pain and Disability shoulder rehabilitation, respiratory muscle strengthening exercises and diaphragmatic breathing exercises - Shoulder Pain, Sleep Quality | Not applicable | Recruiting | Zonguldak Bulent Ecevit University | 70 | 2025-11-25 | 2026-10-21 |
| Photobiomodulation After Nonsurgical Root Canal Treatment Adjunctive Photobiomodulation, Sham Photobiomodulation - Symptomatic Apical Periodontitis, Postoperative Pain | Not applicable | Not yet recruiting | University of Minnesota | 60 | 2026-10-19 | 2026-10-21 |
| Deep Repetitive Transcranial Magnetic Stimulation in the Treatment of Tinnitus DeepTms - Tinnitus, Tinnitus, Bilateral | Not applicable | Recruiting | University of Regensburg | 60 | 2026-09-19 | 2026-10-21 |
| reALIGNing Circadian Rhythm and Promoting Sleep in the Intensive Care Unit Sleep chronobundle, Control - Sleep, Circadian Dysregulation | Early Phase 1 | Not yet recruiting | University of Alberta | 50 | 2026-11-30 | 2026-10-21 |
| Effect of Lower Limb Proprioceptive Neuromuscular Facilitation Combined With Core Stability Training Versus Proprioceptive Neuromuscular Facilitation Alone on Balance and Functional Mobility in Chronic Stroke Survivors Lower Limb PNF Combined with Core Stability Training, Lower Limb PNF alone - Stroke | Not applicable | Recruiting | Ibadat International University, Islamabad | 50 | 2026-07-25 | 2026-10-21 |
| Comparative Effect Between Mulligan Leg Raise and Spinal Mobilization With Limb Movement in Lumbar Radiculopathy Mulligan Leg Raise traction, Spinal Mobilization with Limb Movement - SMWLM - Lumbar Radiculopathy | Not applicable | Recruiting | Foundation University Islamabad | 44 | 2026-09-23 | 2026-10-21 |
| Effects of Technology-Assisted Rehabilitation on Pain and Hand Function in People With Carpal Tunnel Syndrome Technology-Assisted Multimodal Rehabilitation Group (TARG), Conventional Physiotherapy Group (CPG) - Carpal Tunnel Syndrome (CTS) | Not applicable | Completed | Hüseyin Melih Göktuğ Akpulat | 40 | 2025-05-15 | 2026-10-21 |
| Buzzy Bee for Pain and Anxiety Control During Pediatric Dental Local Anesthesia Intervention A: Buzzy® Bee-Assisted Local Anesthesia, Intervention B: Conventional Local Anesthesia Technique - Anesthesia, Anxiety | Not applicable | Recruiting | Tanta University | 40 | 2025-08-01 | 2026-10-21 |
| Effectiveness of Epley Maneuver Versus Semont Maneuver on Dizziness and Balance in Stroke Survivors With Posterior Canal BPPV Epley Maneuver, Semont Maneuver - Stroke | Not applicable | Recruiting | Ibadat International University, Islamabad | 40 | 2026-06-03 | 2026-10-21 |
| Effects of Myofascial Release on Postural Balance and Cervical Muscle Function in Benign Paroxysmal Positional Vertigo Home-Based Balance Exercise Program, Myofascial Release Therapy - Benign Paroxysmal Positional Vertigo | Not applicable | Completed | Karabuk University | 40 | 2021-09-01 | 2026-10-21 |
| Comparison of Extent of Resection of Pituitary Adenoma Via Transnasal Transsphenoidal Approach Using Endoscope Versus Microscope Endoscopic surgery, Microscopic surgery - Pituitary Adenoma | Not applicable | Completed | Sir Ganga Ram Hospital | 38 | 2022-12-04 | 2026-10-21 |
| Transcutaneous Spinal Cord Stimulation for Blood Pressure Augmentation Immediately After Spinal Cord Injury Spinal Cord Stimulation - Spinal Cord Injury Cervical, Spinal Cord Injuries (SCI) | Not applicable | Not yet recruiting | Markey Olson | 20 | 2026-12-01 | 2026-10-21 |
| Hypoglycemia Risk Assessment in Elderly and Senile Female Patients With Type 2 Diabetes Mellitus Comprehensive Geriatric Assessment, Sarcopenia assessment, Laboratory assessment - Type 2 Diabetes Mellitus, Hypoglycemia | Completed | Samara State Medical University | 200 | 2020-01-01 | 2026-10-21 | |
| Multimodal Rehabilitation and Balance Assessment in Parkinson's Disease Multimodal Rehabilitation Program - Parkinson Disease (PD) | Not applicable | Completed | Bilinç Doğruöz Karatekin | 18 | 2024-02-05 | 2026-10-21 |
| Oculomotor-Pupillary AI Biomarkers in Parkinson's Edge-AI Eye-Tracking Assessment - PARKINSON DISEASE (Disorder) | Not yet recruiting | The Hong Kong Polytechnic University | 128 | 2026-11-01 | 2026-10-21 | |
| Whole-Body Point-of-Care Ultrasound in Older Adults Presenting to the Emergency Department After a Fall Whole-body point-of-care ultrasound (POCUS) - Accidental Falls, Aged | Recruiting | Kocaeli City Hospital | 105 | 2026-10-12 | 2026-10-21 | |
| Parkinson's Disease in Type 1 Gaucher Disease Parkinson Disease (PD), Type 1 Gaucher Disease | Recruiting | Icahn School of Medicine at Mount Sinai | 100 | 2026-10-01 | 2026-10-21 | |
| Physical Performance and Cognitive Functions in Patients With Chronic Stroke Stroke | Completed | Kutahya Health Sciences University | 66 | 2025-01-01 | 2026-10-21 | |
| Deep Brain Stimulation Guided by Brain Mapping to Treat Cognitive Impairment Abbott St Jude Medical Infinity™ - Mild Cognitive Impairment (MCI), Mild Cognitive Impairment (MCI) Amnestic | Not applicable | Not yet recruiting | University of Texas Southwestern Medical Center | 6 | 2026-11-01 | 2026-10-21 |
| Prospective Longitudinal Study of Sleep, Brain Activity, and Plasma Analyses in Patients Undergoing Epilepsy Surgery Epilepsy, Sleep | Not yet recruiting | Region Skane | 40 | 2026-09-21 | 2026-10-21 | |
| Dexmedetomidine for Refractory Pain in Palliative Cancer Patients Cancer, Palliative Care, Patient Care | Recruiting | St. Olavs Hospital | 30 | 2026-04-10 | 2026-10-21 | |
| UULEX Reliability in Individuals With Stroke Unsupported Upper Limb Exercise Test [UULEX] - Stroke, UULEX | Not yet recruiting | Karabuk University | 30 | 2026-10-26 | 2026-10-21 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Trial to Evaluate Safety and Efficacy of Anitocabtagene Autoleucel Versus Standard of Care in Newly Diagnosed Multiple Myeloma Anitocabtagene autoleucel, Daratumumab, Bortezomib - Newly Diagnosed Multiple Myeloma | Phase 3 | Not yet recruiting | Kite, A Gilead Company | 600 | 2027-01-01 | 2026-10-21 |
| A Study of HS-10382 Versus Investigator-selected TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CP HS-10382, Imatinib, Dasatinib - Chronic Myeloid Leukemia | Phase 3 | Not yet recruiting | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 408 | 2026-12-01 | 2026-10-21 |
| Fasten Onco Digital Therapy During Neoadjuvant Treatment for Triple-Negative Breast Cancer Fasten Onco, Standard Neoadjuvant Treatment - Triple-Negative Breast Cancer (TNBC) | Not applicable | Not yet recruiting | FASTEN | 144 | 2026-10-30 | 2026-10-21 |
| A Study Investigating the Safety and How the Trispecific T-Cell Engaging Antibody BG-T0920 Works in Adults With Diffuse Large B-cell Lymphoma (DLBCL) and Other Aggressive B-Cell Malignancies BG-T0920 - Diffuse Large B-Cell Lymphoma, B-cell Malignancies | Phase 1 | Not yet recruiting | BeOne Medicines | 70 | 2026-12-11 | 2026-10-21 |
| Oral Care Program for Mouth Side Effects During Head and Neck Radiation Therapy ORAL CARE PRODUCT KIT - Head and Neck Cancer (H&N), Oral Mucositis (Ulcerative) Due to Radiation | Not applicable | Not yet recruiting | UNCANCER LLC | 50 | 2026-11-01 | 2026-10-21 |
| REGN9220 in Combination With Odronextamab in Adult Participants With Relapsed or Refractory Aggressive B-Cell Non-Hodgkin Lymphomas (BCNHLs) REGN9220, Odronextamab - Diffuse Large B-Cell Lymphoma (DLBCL) | Phase 1 / Phase 2 | Not yet recruiting | Regeneron Pharmaceuticals | 36 | 2026-12-07 | 2026-10-21 |
| Chinese Overweight/Obesity Cohort: Metabolic & Comorbidity Risks No intervention; observational assessment only - Obesity & Overweight, Diabetes Mellitus, Type 2 | Not yet recruiting | Shanxi Bethune Hospital | 25974 | 2026-11-01 | 2026-10-21 | |
| Pragmatic Interventions to Advance Cancer Survivor Outcomes Clinical Care decisions - Cancer, Malignant Neoplasm | Not yet recruiting | University of Texas Southwestern Medical Center | 10000 | 2026-11-01 | 2026-10-21 | |
| Non-inferiority Trial Omitting Drainage After Robot-assisted Radical prostatectomY No Pelvic Drain Placement, Pelvic Drain Placement - Prostate Cancer | Not applicable | Not yet recruiting | Shanghai East Hospital | 400 | 2026-10-01 | 2026-10-21 |
| Fruquintinib Combined With Capecitabine as Adjuvant Extended Therapy After R0 Resection and Perioperative Chemotherapy in Patients With Liver-Only Metastatic Colorectal Cancer Fruquintinib Combined With Capecitabine, Follow-up observation - Colorectal Cancer | Phase 3 | Not yet recruiting | West China Hospital | 140 | 2026-10-08 | 2026-10-21 |
| MRD and Imaging Guided Adaptive Neoadjuvant Therapy for Resectable NSCLC PD-1 inhibitor, Carboplatin, Nab-paclitaxel - Non-Small Cell Lung Cancer (NSCLC) | Phase 2 | Not yet recruiting | Peking University People's Hospital | 100 | 2026-11-01 | 2026-10-21 |
| Efficacy and Safety of Ivonescimab Plus Pemetrexed and Platinum-Based Chemotherapy in Advanced Malignant Pleural Mesothelioma Ivonescimab Combined With Chemotherapy - Malignant Pleural Mesothelioma, Advanced | Phase 1 / Phase 2 | Not yet recruiting | Ruijin Hospital | 78 | 2026-11-01 | 2026-10-21 |
| Effects of Supervised Aerobic Exercise on Biomarkers in Patients With nSCLC Receiving Immunotherapy Exercise - Non-Small Cell Lung Cancer, Aerobic Exercise | Not applicable | Not yet recruiting | Izmir Bakircay University | 78 | 2027-01-04 | 2026-10-21 |
| Symptom Monitoring and Management Intervention After CAR-T WAYPOINT - Chimeric Antigen Receptor T-cell Therapy, Hematologic Malignancy | Not applicable | Not yet recruiting | Massachusetts General Hospital | 65 | 2027-03-01 | 2026-10-21 |
| A Study of Ropeg-Interferon in People With Polycythemia Vera Ropeginterferon - Polycythemia Vera (PV), JAK2 Mutation | Phase 2 | Not yet recruiting | Memorial Sloan Kettering Cancer Center | 55 | 2026-10-30 | 2026-10-21 |
| RET-Targeted Molecular Imaging Probes in Prostate Cancer RET-targeted PET/CT molecular imaging, PSMA-targeted PET/CT imaging - Prostate Adenocarcinoma With Focal Neuroendocrine Differentiation, Prostate Cancer | Early Phase 1 | Active not recruiting | Xiangya Hospital of Central South University | 50 | 2026-04-03 | 2026-10-21 |
| PULSAR Radiotherapy Combined With Immunotherapy for High-Risk Advanced Liver Cancer PULSAR (Personalized Ultrafractionated Stereotactic Adaptive Radiotherapy), Immune checkpoint inhibitor-based therapy - Hepatocellular Carcinoma (HCC), Radiotherapy-Induced Immune Priming | Phase 2 | Recruiting | Samsung Medical Center | 38 | 2026-10-15 | 2026-10-21 |
| Comparison of Extent of Resection of Pituitary Adenoma Via Transnasal Transsphenoidal Approach Using Endoscope Versus Microscope Endoscopic surgery, Microscopic surgery - Pituitary Adenoma | Not applicable | Completed | Sir Ganga Ram Hospital | 38 | 2022-12-04 | 2026-10-21 |
| Tacabrutideg and Sonrotoclax, With Response-Guided Obinutuzumab, for the Treatment of Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) Tacabrutideg, Sonrotoclax, Obinutuzumab - Chronic Lymphocytic Leukemia, Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma | Phase 2 | Not yet recruiting | Fred Hutchinson Cancer Center | 30 | 2027-01-01 | 2026-10-21 |
| Integrated ¹⁸F-PSMA-1007 PET/MR Combined With Diffusion-Relaxation Correlation Spectrum Imaging for Preoperative Prediction of Postoperative Adverse Pathology and High ISUP Grade in Prostate Cancer Prostate Cancer | Active not recruiting | Ruijin Hospital | 300 | 2026-10-12 | 2026-10-21 | |
| 68Ga-XMFH01 PET/Fluorescence Imaging in Prostate Cancer 68Ga-XMFH01 PET/CT - Prostate Cancer (Diagnosis), ACP3 | Not applicable | Recruiting | The First Affiliated Hospital of Xiamen University | 25 | 2026-10-21 | 2026-10-21 |
| Multimodal Respiratory Physiotherapy in Women Receiving Radiotherapy for Breast Cancer (RESPIRA-BC) Incentive Spirometry (IS) and Positive Expiratory Pressure (PEP) Training, Individualised Exercise Programme (Aerobic and Resistance Training), Patient Education Programme - Breast Neoplasms | Not applicable | Completed | University of Alcala | 22 | 2022-03-01 | 2026-10-21 |
| Propranolol Hydrochloride Combined With Adebrelimab and Platinum-Based Chemotherapy in Small Cell Lung Cancer Propranolol Hydrochloride, Adebrelimab, Chemotherapy - Small Cell Lung Cancer (SCLC) | Phase 1 | Recruiting | Second Xiangya Hospital of Central South University | 18 | 2026-05-29 | 2026-10-21 |
| Radiotherapy In a Sitting Position for Enhanced Reproducibility Simulation of radiotherapy session in sitting position - Head & Neck Cancer | Not applicable | Not yet recruiting | Centre Leon Berard | 16 | 2026-12-31 | 2026-10-21 |
| Pulsed Stereotactic Ablative Radiotherapy (PULSAR) With Systematic Therapy for Thyroid Cancer Dabrafenib, Trametinib, Pembrolizumab - Anaplastic Thyroid Carcinoma, Thyroid Cancer | Phase 2 | Not yet recruiting | Washington University School of Medicine | 12 | 2026-12-31 | 2026-10-21 |
| Incidental Gallbladder Carcinoma :Incidence and Clinical Significance in Specimens From Routine Cholecystectomies in Sohag Locality histopathology of gall bladder - Gall Bladder Carcinoma | Recruiting | Sohag University | 100 | 2026-09-20 | 2026-10-21 | |
| Safety and Preliminary Antitumor Activity of Ivonescimab Plus Pemetrexed and Platinum-Based Chemotherapy in Advanced Malignant Pleural Mesothelioma Ivonescimab Combined With Chemotherapy - Malignant Pleural Mesothelioma, Advanced | Phase 1 | Active not recruiting | Ruijin Hospital | 9 | 2025-03-12 | 2026-10-21 |
| Propranolol Hydrochloride Combined With Toripalimab and Platinum-based Chemotherapy in Resectable Non-Small Cell Lung Cancer Propranolol Hydrochloride, Toripalimab, Chemotherapy - Resectable Non-Small-Cell Lung Cancer | Phase 1 | Recruiting | Second Xiangya Hospital of Central South University | 9 | 2026-06-01 | 2026-10-21 |
| Lucid BE Biomarkers Study Tissue - Barrett's Esophagus, Barrett's Esophagus With Dysplasia | Not yet recruiting | UNC Lineberger Comprehensive Cancer Center | 40 | 2026-12-01 | 2026-10-21 | |
| Dexmedetomidine for Refractory Pain in Palliative Cancer Patients Cancer, Palliative Care, Patient Care | Recruiting | St. Olavs Hospital | 30 | 2026-04-10 | 2026-10-21 | |
| Real-World Use of Tarlatamab in Chinese Patients With Small-Cell Lung Cancer Tarlatamab - Extensive-Stage Small Cell Lung Cancer | Active not recruiting | Ruijin Hospital | 26 | 2026-08-03 | 2026-10-21 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Trial to Evaluate Safety and Efficacy of Anitocabtagene Autoleucel Versus Standard of Care in Newly Diagnosed Multiple Myeloma Anitocabtagene autoleucel, Daratumumab, Bortezomib - Newly Diagnosed Multiple Myeloma | Phase 3 | Not yet recruiting | Kite, A Gilead Company | 600 | 2027-01-01 | 2026-10-21 |
| Chinese Overweight/Obesity Cohort: Metabolic & Comorbidity Risks No intervention; observational assessment only - Obesity & Overweight, Diabetes Mellitus, Type 2 | Not yet recruiting | Shanxi Bethune Hospital | 25974 | 2026-11-01 | 2026-10-21 | |
| Screening Elderly Adults in Rural Communities for Heart Failure Using an NT-proBNP-Guided Strategy in China (SEARCH-HF) Symptom-based heart failure screening, NT-proBNP-guided heart failure screening - Heart Failure | Not applicable | Recruiting | Jiangsu Taizhou People's Hospital | 2532 | 2026-10-01 | 2026-10-21 |
| The PALMETTO Study ReValve System - Mitral Regurgitation | Not applicable | Not yet recruiting | ReValve Solutions Inc. | 10 | 2026-11-01 | 2026-10-21 |
| Randomized Interventional Clinical Trial on the Prevention of Atrial Fibrillation Using Colchicine, Amiodarone And a Posterior Pericardiotomy. Colchicine, Amiodarone, Posterior pericardiotomy - Atrial Fibrillation (AF) | Phase 3 | Not yet recruiting | Elsan | 636 | 2027-01-01 | 2026-10-21 |
| Coronary MicrovAscular Diseases Intervention With Compound Danshen Dropping Pills Compound Danshen Dripping Pills, Placebo - Coronary Microvascular Disease | Phase 4 | Not yet recruiting | Qilu Hospital of Shandong University | 496 | 2026-10-01 | 2026-10-21 |
| SAFELY RULING OUT DEEP VEIN THROMBOSIS IN PREGNANCY WITH THE LEFt SCORE AND TRIMESTER-ADJUSTED D-DIMER CUTOFFS (the PREG-DVT Study): A PROSPECTIVE COHORT STUDY. D-dimer - Pregnancy Related, Deep Vein Thrombosis | Not applicable | Not yet recruiting | Marc Righini | 330 | 2027-04-01 | 2026-10-21 |
| Exercise, Mediterranean Diet and Inflammation in Heart Failure Structured exercise training program, Mediterranean diet counseling, Standard heart failure management - Heart Failure, Heart Failure Preserved Ejection Fraction | Not applicable | Not yet recruiting | Hospital Severo Ochoa | 214 | 2026-11-01 | 2026-10-21 |
| Effect of Home and Remote Blood Pressure Monitoring Via Home BP Monitoring System (HMS) on Adults With Hypertension in Taiwan Case-manager surveillance with physician-guided remote titration, Passive data review at clinic visits - Hypertension | Not applicable | Completed | National Taiwan University Hospital Hsin-Chu Branch | 211 | 2022-10-06 | 2026-10-21 |
| Optical Coherence Tomography-Assisted Strategy for Interventional Management of Symptomatic Carotid Stenosis (OASIS-C) OCT guided endovascular treatment - Carotid Stenosis | Not applicable | Not yet recruiting | Beijing Tiantan Hospital | 100 | 2026-11-01 | 2026-10-21 |
| A Novel Wire-Reinforced Fenestration of a Hybrid Frozen Elephant Trunk Device for Supra-Aortic Branch Vessel Stenting During Aortic Arch Replacement Modified Supra-Aortic Frozen Elephant Trunk (SA-FET) Device - Aortic Aneurysm, Aortic Dissection | Not applicable | Not yet recruiting | University of Maryland, Baltimore | 100 | 2026-11-01 | 2026-10-21 |
| Prevalence of Obstructive Sleep Apnea in HHT and HHT-specific Challenges in OSA-therapy - a Retrospective Cohort Study Hereditary Hemorrhagic Telangiectasia (HHT), Obstructive Sleep Apnea (OSA) | Not yet recruiting | University Hospital, Essen | 1000 | 2026-10-01 | 2026-10-21 | |
| Prophylactic Ondansetron for Preventing Spinal Anesthesia-Induced Hypotension in Elective Cesarean Section Ondansetron, Placebo (0.9% Sodium Chloride) - Hypotension, Spinal Anesthesia | Phase 4 | Completed | Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital | 96 | 2026-02-02 | 2026-10-21 |
| AI-based Algorithm Development for Improved Diagnostics in the Intensive Care and Acute Stroke Setting Using Electroencephalography Hemorrhagic Stroke, Intracerebral, Subarachnoid Haemorrhage (SAH) | Recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 825 | 2026-03-26 | 2026-10-21 | |
| Effect of Lower Limb Proprioceptive Neuromuscular Facilitation Combined With Core Stability Training Versus Proprioceptive Neuromuscular Facilitation Alone on Balance and Functional Mobility in Chronic Stroke Survivors Lower Limb PNF Combined with Core Stability Training, Lower Limb PNF alone - Stroke | Not applicable | Recruiting | Ibadat International University, Islamabad | 50 | 2026-07-25 | 2026-10-21 |
| HUGO-SLEEVE: Evaluating the Feasibility of Robotic Sleeve Gastrectomy With a New Platform Sleeve Gastrectomy using Hugo RAS platform - Obesity (BMI > 35), Obesity (BMI > 35) and Diabetes Mellitus | Not applicable | Recruiting | Universitätsklinikum Hamburg-Eppendorf | 50 | 2026-06-04 | 2026-10-21 |
| Psychometric Evaluation of the Traditional Chinese Multidimensional Fatigue Inventory in Patients With Heart Failure Questionnaire investigate - Heart Failure, Fatigue Severity Scale | Not yet recruiting | Kaohsiung Medical University | 400 | 2026-10-31 | 2026-10-21 | |
| Effectiveness of Epley Maneuver Versus Semont Maneuver on Dizziness and Balance in Stroke Survivors With Posterior Canal BPPV Epley Maneuver, Semont Maneuver - Stroke | Not applicable | Recruiting | Ibadat International University, Islamabad | 40 | 2026-06-03 | 2026-10-21 |
| AI-Based CT Analysis of Coronary Plaque Evolution Coronary Artery Disease | Not yet recruiting | Zhejiang Hospital | 326 | 2026-10-01 | 2026-10-21 | |
| Factors Influencing Outcomes in ECMO and Impella Patients: Metabolic and Thyroid Hormone Dynamics Cardiogenic Shock, Euthyroid Sick Syndrome | Recruiting | Gottsegen National Cardiovascular Institute | 160 | 2026-08-17 | 2026-10-21 | |
| Donor Derived Cell Free DNA (Dd-cfDNA) as a Biomarker for Allograft Rejection in Heart Transplant Recipients Donor-derived cell free DNA - Heart Transplantation | Enrolling by invitation | University of Aarhus | 100 | 2026-09-01 | 2026-10-21 | |
| Physical Performance and Cognitive Functions in Patients With Chronic Stroke Stroke | Completed | Kutahya Health Sciences University | 66 | 2025-01-01 | 2026-10-21 | |
| UULEX Reliability in Individuals With Stroke Unsupported Upper Limb Exercise Test [UULEX] - Stroke, UULEX | Not yet recruiting | Karabuk University | 30 | 2026-10-26 | 2026-10-21 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Sleep MAPP in the Polytrauma/TBI System of Care Sleep MAPP Care Pathway - Insomnia Disorder, Mild Traumatic Brain Injury | Not applicable | Not yet recruiting | VA Office of Research and Development | 900 | 2027-01-01 | 2026-10-21 |
| Salience Network Informed rTMS for PTSD Active MRI-Guided intermittent theta burst stimulation (iTBS), Sham MRI-Guided intermittent theta burst stimulation (iTBS) - Stress Disorders, Post-Traumatic | Phase 2 | Not yet recruiting | VA Office of Research and Development | 84 | 2027-07-01 | 2026-10-21 |
| Evaluation of a Multi-Layered Digital Phenotyping, Digital Safety Plan, and Pharmacogenomic Intervention for Suicide Prevention in Adults With Depression Digital Monitoring (Active/Passive EMA), Ecological Momentary Intervention (EMI) via Digital Safety Plan, Pharmacogenetic-Guided Care and Therapeutic Drug Monitoring - Depressive Disorder, Major Depressive Disorder, Suicidal Ideation | Not applicable | Recruiting | Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz | 525 | 2025-09-01 | 2026-10-21 |
| A School-Based Intervention to Prevent Disordered Eating in Middle School Students School-Based Disordered Eating Prevention Education Program - Disordered Eating Behaviors | Not applicable | Completed | Izmir Katip Celebi University | 235 | 2025-11-02 | 2026-10-21 |
| PATH to Reducing Burnout Among Peers Who Deliver Overdose Prevention Services (R33 Phase Clinical Trial) PATH (Peer Advanced Training for total Health) - Burnout, Secondary Trauma | Not applicable | Enrolling by invitation | Chestnut Health Systems | 200 | 2026-10-12 | 2026-10-21 |
| Effectiveness of a Music Therapy Intervention in Cancer Patients Undergoing Active Treatment at the Jaén University Hospital: a Non-randomized Controlled Trial. Music Therapy - Anxiety, Signs and Symptoms | Not applicable | Completed | University of Jaén | 120 | 2025-04-01 | 2026-10-21 |
| The Effects of Finger Painting as an Intervention During Nebulization Therapy on Fear and Anxiety Levels in Children: A Randomized Controlled Trial the finger-painting - CHİLD | Not applicable | Completed | Firat University | 106 | 2025-08-03 | 2026-10-21 |
| The Effect of Mind Mapping-Based Education on Postoperative Pain, Kinesiophobia, and Discharge Readiness in Patients Undergoing Total Knee Arthroplasty Mind Mapping-Based Education - Total Knee Arthroplasty | Not applicable | Recruiting | Inonu University | 102 | 2026-06-01 | 2026-10-21 |
| Methyl Donor-Rich Diet in the Postpartum Period Methyl Donor-Rich Dietary Intervention - Postpartum Depression (PPD), Breastfeeding | Not applicable | Recruiting | Istanbul University - Cerrahpasa | 100 | 2026-05-21 | 2026-10-21 |
| Effects of Respiratory Muscle Strengthening and Diaphragmatic Breathing on Shoulder Pain and Disability shoulder rehabilitation, respiratory muscle strengthening exercises and diaphragmatic breathing exercises - Shoulder Pain, Sleep Quality | Not applicable | Recruiting | Zonguldak Bulent Ecevit University | 70 | 2025-11-25 | 2026-10-21 |
| Hybrid Pilot of Personalized Parent-Child Interaction Therapy Behavioral Parent Training - Disruptive Behaviors | Not applicable | Not yet recruiting | San Diego State University | 60 | 2027-04-01 | 2026-10-21 |
| Postsurgical Pain and Opioid Use in Older Adults: Effects of Mild Cognitive Impairment Mild Cognitive Impairment (MCI), Opioid Use | Not yet recruiting | Miklos Kertai | 552 | 2027-01-01 | 2026-10-21 | |
| reALIGNing Circadian Rhythm and Promoting Sleep in the Intensive Care Unit Sleep chronobundle, Control - Sleep, Circadian Dysregulation | Early Phase 1 | Not yet recruiting | University of Alberta | 50 | 2026-11-30 | 2026-10-21 |
| Buzzy Bee for Pain and Anxiety Control During Pediatric Dental Local Anesthesia Intervention A: Buzzy® Bee-Assisted Local Anesthesia, Intervention B: Conventional Local Anesthesia Technique - Anesthesia, Anxiety | Not applicable | Recruiting | Tanta University | 40 | 2025-08-01 | 2026-10-21 |
| Adapting the Sensory Environment to Reduce Stress in Children With Autism During Dental Visits Sensory-Adapted Dental Environment - Autism, Autism Disorders and Maternal Stress | Not applicable | Active not recruiting | Jagiellonian University | 40 | 2026-10-01 | 2026-10-21 |
| Cannabidiol in Opioid Use Disorder and Chronic Pain With Buprenorphine 400 mg Cannabidiol, 800 mg Cannabidiol, 1200 mg Cannabidiol - Chronic Pain, Opioid Use Disorder | Early Phase 1 | Recruiting | Yale University | 34 | 2021-12-08 | 2026-10-21 |
| SONATA Dose Duration LIFU for OCD ATTN201 - Low Intensity Focused Ultrasound - Obsessive - Compulsive Disorder | Phase 2 | Recruiting | University of Pennsylvania | 20 | 2026-09-15 | 2026-10-21 |
| Coping and Adaptation for Recovery From Moral Injury: A Group Intervention for Clinical Psychology Residents CARE-MI Group Intervention - Moral Distress, Moral Injury | Not applicable | Not yet recruiting | Universidad Complutense de Madrid | 10 | 2026-12-10 | 2026-10-21 |
| Physical Performance and Cognitive Functions in Patients With Chronic Stroke Stroke | Completed | Kutahya Health Sciences University | 66 | 2025-01-01 | 2026-10-21 | |
| Deep Brain Stimulation Guided by Brain Mapping to Treat Cognitive Impairment Abbott St Jude Medical Infinity™ - Mild Cognitive Impairment (MCI), Mild Cognitive Impairment (MCI) Amnestic | Not applicable | Not yet recruiting | University of Texas Southwestern Medical Center | 6 | 2026-11-01 | 2026-10-21 |
| Community-Based Intensive Treatment (CBIT): Meeting the Complex Needs of Rural Adults With Serious Mental Illness Severe Mental Illness, Hospitalizations Psychiatric | Not yet recruiting | Yale University | 25 | 2026-10-04 | 2026-10-21 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of the Safety and Efficacy of Prime Editing (PM647a) in Participants With Alpha-1 Antitrypsin Deficiency PM647a - Alpha-1 Antitrypsin Deficiency, Alpha-1 Antitrypsin Deficiency-associated Lung Disease | Phase 1 / Phase 2 | Not yet recruiting | Prime Medicine, Inc. | 54 | 2026-10-01 | 2026-10-21 |
| Chinese Overweight/Obesity Cohort: Metabolic & Comorbidity Risks No intervention; observational assessment only - Obesity & Overweight, Diabetes Mellitus, Type 2 | Not yet recruiting | Shanxi Bethune Hospital | 25974 | 2026-11-01 | 2026-10-21 | |
| Preoperative Pneumococcal and Influenza Vaccination to Prevent Postoperative Pulmonary Infection in Patients Undergoing Lung Resection for Pulmonary Nodules or Lung Cancer 23-valent pneumococcal polysaccharide vaccine, Quadrivalent split-virion influenza vaccine - Pneumococcal Polysaccharide Vaccine, Influenza Vaccines | Phase 4 | Not yet recruiting | The First Affiliated Hospital of Guangzhou Medical University | 1278 | 2026-11-01 | 2026-10-21 |
| VATS or Intrapleural Enzymatic Therapy for Patients With Empyema. VATS group, IET - Empyema, Pleural, Pleural Infections | Phase 4 | Not yet recruiting | Amsterdam UMC | 164 | 2026-10-01 | 2026-10-21 |
| Essential Oil Mouthwash - Oral Hygiene Essential oil mouthwash, Chlorhexidine gluconate alcohol-free mouthwash, Povidone-iodine alcohol-free mouthwash - Oral Hygiene, Oral Health, Dental Plaque | Not applicable | Completed | China Medical University, Taiwan | 150 | 2025-04-12 | 2026-10-21 |
| MRD and Imaging Guided Adaptive Neoadjuvant Therapy for Resectable NSCLC PD-1 inhibitor, Carboplatin, Nab-paclitaxel - Non-Small Cell Lung Cancer (NSCLC) | Phase 2 | Not yet recruiting | Peking University People's Hospital | 100 | 2026-11-01 | 2026-10-21 |
| Prevalence of Obstructive Sleep Apnea in HHT and HHT-specific Challenges in OSA-therapy - a Retrospective Cohort Study Hereditary Hemorrhagic Telangiectasia (HHT), Obstructive Sleep Apnea (OSA) | Not yet recruiting | University Hospital, Essen | 1000 | 2026-10-01 | 2026-10-21 | |
| Channa Striata and Curcuma Domestica Supplementation in Patients With Active Pulmonary Tuberculosis CHANA STRIATA AND CURCUMA, Maltodextrin (Placebo) - Pulmonary Tuberculosis | Not applicable | Recruiting | DINA KEUMALA SARI | 80 | 2026-08-01 | 2026-10-21 |
| Efficacy and Safety of Ivonescimab Plus Pemetrexed and Platinum-Based Chemotherapy in Advanced Malignant Pleural Mesothelioma Ivonescimab Combined With Chemotherapy - Malignant Pleural Mesothelioma, Advanced | Phase 1 / Phase 2 | Not yet recruiting | Ruijin Hospital | 78 | 2026-11-01 | 2026-10-21 |
| COPD Prevalence and Risk Factors Among Saudi Adults Over 18 in Taif Chronic Obstructive Pulmonary Disease (COPD) | Completed | Taif University | 777 | 2024-10-24 | 2026-10-21 | |
| Effects of Supervised Aerobic Exercise on Biomarkers in Patients With nSCLC Receiving Immunotherapy Exercise - Non-Small Cell Lung Cancer, Aerobic Exercise | Not applicable | Not yet recruiting | Izmir Bakircay University | 78 | 2027-01-04 | 2026-10-21 |
| EFFECT OF COMBINED VIRTUAL REALITY-GUIDED BREATHING AND AEROBIC TRAINING ON VENTILATORY FUNCTION IN PATIENTS WITH COPD VR-Based Pulmonary Rehabilitation Group, Conventional Pulmonary Rehabilitation Group - Chronic Obstructive Lung Disease | Not applicable | Not yet recruiting | Cairo University | 60 | 2026-11-01 | 2026-10-21 |
| PERCE-MUCO: Perceptions and Expectations of People With Cystic Fibrosis Regarding a Change in Treatment Cystic Fibrosis (CF) | Recruiting | Fondation Ildys | 343 | 2026-07-09 | 2026-10-21 | |
| A Randomized, Double-Blind, Placebo-Controlled Phase Ib Study of Multiple Ascending Doses of EB070 Injection in Adults With Moderate-to-Severe Asthma EB070 - Asthma | Phase 1 | Not yet recruiting | Biotech Pharmaceutical Co., Ltd. | 20 | 2026-09-30 | 2026-10-21 |
| Circuit Breathing Exercise on Smoking Cessation Among Youth E-Cigarette Users Circuit breathing, Diaphragmatic Breathing, Normal Breathing Condition - E Cigarette Use | Not applicable | Recruiting | Chulalongkorn University | 20 | 2026-08-15 | 2026-10-21 |
| Propranolol Hydrochloride Combined With Adebrelimab and Platinum-Based Chemotherapy in Small Cell Lung Cancer Propranolol Hydrochloride, Adebrelimab, Chemotherapy - Small Cell Lung Cancer (SCLC) | Phase 1 | Recruiting | Second Xiangya Hospital of Central South University | 18 | 2026-05-29 | 2026-10-21 |
| Safety and Preliminary Antitumor Activity of Ivonescimab Plus Pemetrexed and Platinum-Based Chemotherapy in Advanced Malignant Pleural Mesothelioma Ivonescimab Combined With Chemotherapy - Malignant Pleural Mesothelioma, Advanced | Phase 1 | Active not recruiting | Ruijin Hospital | 9 | 2025-03-12 | 2026-10-21 |
| Propranolol Hydrochloride Combined With Toripalimab and Platinum-based Chemotherapy in Resectable Non-Small Cell Lung Cancer Propranolol Hydrochloride, Toripalimab, Chemotherapy - Resectable Non-Small-Cell Lung Cancer | Phase 1 | Recruiting | Second Xiangya Hospital of Central South University | 9 | 2026-06-01 | 2026-10-21 |
| Real-World Use of Tarlatamab in Chinese Patients With Small-Cell Lung Cancer Tarlatamab - Extensive-Stage Small Cell Lung Cancer | Active not recruiting | Ruijin Hospital | 26 | 2026-08-03 | 2026-10-21 | |
| Upper Airway Morphology and Physiology During Graded Positive Pressure and Nasal High Flow: An MRI Study Nasal High Flow, Continuous Positive Airway Pressure - Chronic Obstructive Pulmonary Disease (COPD) | Not yet recruiting | Klinikum Dortmund Wirbelsäulenchirurgie | 20 | 2026-10-01 | 2026-10-21 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| IBI3034 Study in Healthy Adults and Patients With Primary IgA Nephropathy IBI3034, Placebo, Telitacicept - IgA Nephropathy (IgAN) | Phase 1 | Not yet recruiting | Innovent Biologics (Suzhou) Co. Ltd. | 100 | 2026-10-15 | 2026-10-21 |
| Probiotic Supplement for Recurrent UTIs in Healthy Women (L. Plantarum, L. Rhamnosus, B. Lactis) Dietary Supplement containing probiotics, Placebo - Recurrent Urinary Tract Infections | Not applicable | Active not recruiting | Synbalance S.r.l. | 70 | 2026-10-14 | 2026-10-21 |
| Chinese Overweight/Obesity Cohort: Metabolic & Comorbidity Risks No intervention; observational assessment only - Obesity & Overweight, Diabetes Mellitus, Type 2 | Not yet recruiting | Shanxi Bethune Hospital | 25974 | 2026-11-01 | 2026-10-21 | |
| Non-inferiority Trial Omitting Drainage After Robot-assisted Radical prostatectomY No Pelvic Drain Placement, Pelvic Drain Placement - Prostate Cancer | Not applicable | Not yet recruiting | Shanghai East Hospital | 400 | 2026-10-01 | 2026-10-21 |
| Acupuncture for Symptom Burden and Quality of Life in Patients With End-Stage Kidney Disease Acupuncture, Sham Acupuncture - End Stage Kidney Disease (ESKD) | Not applicable | Not yet recruiting | University General Hospital of Heraklion | 160 | 2026-12-01 | 2026-10-21 |
| Acupressure as Complementary Analgesia in Shock Wave Lithotripsy Acupressure, Sham Acupressure - Acupressure, Urinary Calculi | Not applicable | Recruiting | Medipol University | 105 | 2026-10-10 | 2026-10-21 |
| Methyl Donor-Rich Diet in the Postpartum Period Methyl Donor-Rich Dietary Intervention - Postpartum Depression (PPD), Breastfeeding | Not applicable | Recruiting | Istanbul University - Cerrahpasa | 100 | 2026-05-21 | 2026-10-21 |
| Prophylactic Norepinephrine for Prevention of Acute Kidney Injury in Living-Donor Liver Transplantation Norepinephrine started prophylactically immediately post induction of general anesthesia, Norepinephrine infusion will only initiated if mean arterial pressure <65 mmHg despite preload optimization (stroke volume variation <12%) or if systemic vascular resistance <800 dynes•s/cm⁵ - Noradrenaline | Not applicable | Not yet recruiting | Mansoura University | 84 | 2026-10-15 | 2026-10-21 |
| Gamified Interactive Narrative (REPRO-QUEST) on Sexual Health Literacy and Sexually Transmitted Infection Prevention Behaviors REPRO-QUEST Interactive Narrative, Educational Booklet - Sexual Health, Sexually Transmitted Infection (STI) | Not applicable | Completed | Karamanoğlu Mehmetbey University | 82 | 2026-04-04 | 2026-10-21 |
| Measured Versus Hemoglobin-Calculated Postpartum Blood Loss in Waterbirth Water immersion during labor and birth - Postpartum Hemorrhage, Waterbirth | Not yet recruiting | University of Campania Luigi Vanvitelli | 600 | 2027-04-01 | 2026-10-21 | |
| RET-Targeted Molecular Imaging Probes in Prostate Cancer RET-targeted PET/CT molecular imaging, PSMA-targeted PET/CT imaging - Prostate Adenocarcinoma With Focal Neuroendocrine Differentiation, Prostate Cancer | Early Phase 1 | Active not recruiting | Xiangya Hospital of Central South University | 50 | 2026-04-03 | 2026-10-21 |
| Long Term Outcome After Use of Vacuum-induced Tamponade for Postpartum Hemorrhage Postpartum Hemorrhage, Treatment Outcome | Recruiting | University of Zurich | 380 | 2026-10-01 | 2026-10-21 | |
| Neonatal Outcomes on Direct Fetal Intravenous Immunoglobulin During Intrauterine Transfusion for Rhesus Isoimmunization Intrauterine Transfusion, Intravenous immunoglobulin (IVIG) - Hemolytic Disease of the Newborn, Fetal Anemia | Phase 2 | Recruiting | Post Graduate Institute of Medical Education and Research, Chandigarh | 30 | 2026-05-25 | 2026-10-21 |
| Integrated ¹⁸F-PSMA-1007 PET/MR Combined With Diffusion-Relaxation Correlation Spectrum Imaging for Preoperative Prediction of Postoperative Adverse Pathology and High ISUP Grade in Prostate Cancer Prostate Cancer | Active not recruiting | Ruijin Hospital | 300 | 2026-10-12 | 2026-10-21 | |
| Clinical, Biochemical, and Cytogenetic Heterogeneity in Mosaic 46,XX/47,XXY Sex Chromosome Aneuploidy Klinefelter Syndrome (47, XXY), Sex Chromosome Aneuploidy | Completed | Université Paris-Saclay | 257 | 2022-01-15 | 2026-10-21 | |
| 68Ga-XMFH01 PET/Fluorescence Imaging in Prostate Cancer 68Ga-XMFH01 PET/CT - Prostate Cancer (Diagnosis), ACP3 | Not applicable | Recruiting | The First Affiliated Hospital of Xiamen University | 25 | 2026-10-21 | 2026-10-21 |
| Manual Acupuncture for Intradialytic Fatigue in CKD Patients Manual Acupuncture, Sham Acupuncture - Intradialytic Fatigue, Chronic Kidney Disease | Not applicable | Not yet recruiting | Universitas Indonesia | 19 | 2026-10-01 | 2026-10-21 |
| Clinical, Functional, and Therapeutic Characterization of Women With Urinary Incontinence and Analysis of Factors Associated With Treatment Response Artificial intelligence clinical decision support model - Urinary Incontinence (UI) | Not yet recruiting | Javier Pereira | 80 | 2026-12-01 | 2026-10-21 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Trial to Evaluate Safety and Efficacy of Anitocabtagene Autoleucel Versus Standard of Care in Newly Diagnosed Multiple Myeloma Anitocabtagene autoleucel, Daratumumab, Bortezomib - Newly Diagnosed Multiple Myeloma | Phase 3 | Not yet recruiting | Kite, A Gilead Company | 600 | 2027-01-01 | 2026-10-21 |
| A Study of HS-10382 Versus Investigator-selected TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CP HS-10382, Imatinib, Dasatinib - Chronic Myeloid Leukemia | Phase 3 | Not yet recruiting | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 408 | 2026-12-01 | 2026-10-21 |
| Long-Term Safety and Tolerability of Nizubaglustat in Participants With Rare Lysosomal Disorders AZ-3102 - Niemann-Pick Disease Type C, GM2 Gangliosidosis | Phase 2 / Phase 3 | Not yet recruiting | Azafaros B.V. | 218 | 2026-12-10 | 2026-10-21 |
| A Study Investigating the Safety and How the Trispecific T-Cell Engaging Antibody BG-T0920 Works in Adults With Diffuse Large B-cell Lymphoma (DLBCL) and Other Aggressive B-Cell Malignancies BG-T0920 - Diffuse Large B-Cell Lymphoma, B-cell Malignancies | Phase 1 | Not yet recruiting | BeOne Medicines | 70 | 2026-12-11 | 2026-10-21 |
| LAM-001 for the Treatment of Sarcoidosis Associated Pulmonary Hypertension (SAPH) Placebo, LAM-001 - Sarcoidosis Associated Pulmonary Hypertension | Phase 2 | Not yet recruiting | IRulya Therapeutics Inc. | 60 | 2026-12-01 | 2026-10-21 |
| REGN9220 in Combination With Odronextamab in Adult Participants With Relapsed or Refractory Aggressive B-Cell Non-Hodgkin Lymphomas (BCNHLs) REGN9220, Odronextamab - Diffuse Large B-Cell Lymphoma (DLBCL) | Phase 1 / Phase 2 | Not yet recruiting | Regeneron Pharmaceuticals | 36 | 2026-12-07 | 2026-10-21 |
| Combination Therapy With Danazol, Prednisolone, and Thalidomide for Thalidomide-Refractory Transfusion-Dependent β-Thalassemia Thalidomide, Danazol, Prednisolone - Beta-Thalassemia, Thalassemia | Phase 3 | Recruiting | Khyber Medical University Peshawar | 172 | 2026-10-12 | 2026-10-21 |
| Prevalence of Obstructive Sleep Apnea in HHT and HHT-specific Challenges in OSA-therapy - a Retrospective Cohort Study Hereditary Hemorrhagic Telangiectasia (HHT), Obstructive Sleep Apnea (OSA) | Not yet recruiting | University Hospital, Essen | 1000 | 2026-10-01 | 2026-10-21 | |
| Symptom Monitoring and Management Intervention After CAR-T WAYPOINT - Chimeric Antigen Receptor T-cell Therapy, Hematologic Malignancy | Not applicable | Not yet recruiting | Massachusetts General Hospital | 65 | 2027-03-01 | 2026-10-21 |
| Sonrotoclax Plus Azacitidine in Patients With MDS-IB2 Sonrotoclax, Azacitidine (AZA) - Myelodysplastic Syndromes, High Risk | Phase 1 / Phase 2 | Recruiting | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 60 | 2026-10-15 | 2026-10-21 |
| Conditioning Regimen Containing Low-Dose ATG for the Treatment of AA Receiving sUCBT Anti-Thymocyte Globulin (Rabbit) (Thymoglobulin®) - Aplastic Anaemia | Phase 2 | Not yet recruiting | Anhui Provincial Hospital | 59 | 2027-08-01 | 2026-10-21 |
| A Study of Ropeg-Interferon in People With Polycythemia Vera Ropeginterferon - Polycythemia Vera (PV), JAK2 Mutation | Phase 2 | Not yet recruiting | Memorial Sloan Kettering Cancer Center | 55 | 2026-10-30 | 2026-10-21 |
| Neonatal Outcomes on Direct Fetal Intravenous Immunoglobulin During Intrauterine Transfusion for Rhesus Isoimmunization Intrauterine Transfusion, Intravenous immunoglobulin (IVIG) - Hemolytic Disease of the Newborn, Fetal Anemia | Phase 2 | Recruiting | Post Graduate Institute of Medical Education and Research, Chandigarh | 30 | 2026-05-25 | 2026-10-21 |
| Tacabrutideg and Sonrotoclax, With Response-Guided Obinutuzumab, for the Treatment of Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) Tacabrutideg, Sonrotoclax, Obinutuzumab - Chronic Lymphocytic Leukemia, Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma | Phase 2 | Not yet recruiting | Fred Hutchinson Cancer Center | 30 | 2027-01-01 | 2026-10-21 |
| Safety of Anticoagulation Therapy in Cirrhotic Patients With PVT and Severe Thrombocytopenia Anticoagulation Therapy - Thrombocytopenia Related to Chronic Liver Disease, Anticoagulation Treatment | Completed | Qilu Hospital of Shandong University | 304 | 2025-09-01 | 2026-10-21 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Clinical Study of AHB-121 in Healthy Participants and Chronic Hepatitis B (CHB) Participants AHB-121, Placebo - Chronic Hepatitis B Virus | Phase 1 | Not yet recruiting | Ausper Biopharma Co., Ltd. | 110 | 2026-10-28 | 2026-10-21 |
| A Study of the Safety and Efficacy of Prime Editing (PM647a) in Participants With Alpha-1 Antitrypsin Deficiency PM647a - Alpha-1 Antitrypsin Deficiency, Alpha-1 Antitrypsin Deficiency-associated Lung Disease | Phase 1 / Phase 2 | Not yet recruiting | Prime Medicine, Inc. | 54 | 2026-10-01 | 2026-10-21 |
| Chinese Overweight/Obesity Cohort: Metabolic & Comorbidity Risks No intervention; observational assessment only - Obesity & Overweight, Diabetes Mellitus, Type 2 | Not yet recruiting | Shanxi Bethune Hospital | 25974 | 2026-11-01 | 2026-10-21 | |
| Cold Water Papillary Irrigation Plus Rectal NSAIDs vs Rectal NSAIDs Alone for Post-ERCP Pancreatitis (COLD) Cold water irrigation of the papilla, Rectal NSAID (diclofenac 100 mg) - Post ERCP Pancreatitis, Acute Pancreatitis (AP) | Not applicable | Not yet recruiting | University Hospital Virgen de las Nieves | 250 | 2026-11-01 | 2026-10-21 |
| Fruquintinib Combined With Capecitabine as Adjuvant Extended Therapy After R0 Resection and Perioperative Chemotherapy in Patients With Liver-Only Metastatic Colorectal Cancer Fruquintinib Combined With Capecitabine, Follow-up observation - Colorectal Cancer | Phase 3 | Not yet recruiting | West China Hospital | 140 | 2026-10-08 | 2026-10-21 |
| Assessment of Nutritional Status in Celiac Disease Using Muscle Ultrasound in Pediatric Patients. performing muscle ultrasonography on patients - Celiac Disease in Children, Nutritional Assessment | Not applicable | Enrolling by invitation | Ondokuz Mayıs University | 120 | 2026-08-03 | 2026-10-21 |
| AI-SC Multi-center Study evaluate the alignment between AI-SC recommendations and LT-SC decisions, Multi AI-SC model - Liver Cirrhosis | Active not recruiting | University Health Network, Toronto | 1000 | 2026-04-01 | 2026-10-21 | |
| Topical Nitroglycerin Versus Lateral Internal Sphincterotomy for Chronic Anal Fissure Topical 0.2% Glyceryl Trinitrate (Nitroglycerin) Ointment, Lateral Internal Sphincterotomy - Chronic Anal Fissure | Not applicable | Completed | Sheikh Zayed Federal Postgraduate Medical Institute | 72 | 2026-06-15 | 2026-10-21 |
| Hasson Versus Veress Access With Umbilical Versus Epigastric Gallbladder Extraction in Laparoscopic Cholecystectomy Hasson open access and umbilical gallbladder extraction, Veress needle access and epigastric gallbladder extraction - Cholelithiasis, Symptomatic Gallstone Disease | Not applicable | Completed | Sedat Tan | 58 | 2019-09-20 | 2026-10-21 |
| PULSAR Radiotherapy Combined With Immunotherapy for High-Risk Advanced Liver Cancer PULSAR (Personalized Ultrafractionated Stereotactic Adaptive Radiotherapy), Immune checkpoint inhibitor-based therapy - Hepatocellular Carcinoma (HCC), Radiotherapy-Induced Immune Priming | Phase 2 | Recruiting | Samsung Medical Center | 38 | 2026-10-15 | 2026-10-21 |
| PERCE-MUCO: Perceptions and Expectations of People With Cystic Fibrosis Regarding a Change in Treatment Cystic Fibrosis (CF) | Recruiting | Fondation Ildys | 343 | 2026-07-09 | 2026-10-21 | |
| Safety of Anticoagulation Therapy in Cirrhotic Patients With PVT and Severe Thrombocytopenia Anticoagulation Therapy - Thrombocytopenia Related to Chronic Liver Disease, Anticoagulation Treatment | Completed | Qilu Hospital of Shandong University | 304 | 2025-09-01 | 2026-10-21 | |
| Incidental Gallbladder Carcinoma :Incidence and Clinical Significance in Specimens From Routine Cholecystectomies in Sohag Locality histopathology of gall bladder - Gall Bladder Carcinoma | Recruiting | Sohag University | 100 | 2026-09-20 | 2026-10-21 | |
| Lucid BE Biomarkers Study Tissue - Barrett's Esophagus, Barrett's Esophagus With Dysplasia | Not yet recruiting | UNC Lineberger Comprehensive Cancer Center | 40 | 2026-12-01 | 2026-10-21 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Long-Term Safety and Tolerability of Nizubaglustat in Participants With Rare Lysosomal Disorders AZ-3102 - Niemann-Pick Disease Type C, GM2 Gangliosidosis | Phase 2 / Phase 3 | Not yet recruiting | Azafaros B.V. | 218 | 2026-12-10 | 2026-10-21 |
| Preventive Effectiveness of Primary Care Physician-led CGM-supported Comprehensive Intervention on Cardio-metabolic-immune Diseases in Community Patients With Type 2 Diabetes (Community Diabetes Control Project) comprehensive intervention - Type 2 Diabetes Mellitus | Not applicable | Not yet recruiting | Xiangya Hospital of Central South University | 15400 | 2026-11-30 | 2026-10-21 |
| Effects of Mango on Insulin Sensitivity in Prediabetes Mango juice, Control Beverage - Pre Diabetes | Not applicable | Not yet recruiting | Clinical Nutrition Research Center, Illinois Institute of Technology | 64 | 2026-10-28 | 2026-10-21 |
| Chinese Overweight/Obesity Cohort: Metabolic & Comorbidity Risks No intervention; observational assessment only - Obesity & Overweight, Diabetes Mellitus, Type 2 | Not yet recruiting | Shanxi Bethune Hospital | 25974 | 2026-11-01 | 2026-10-21 | |
| A Study to Learn More About Friedrich's Ataxia in People Living in the Gulf Cooperation Council (GCC) Region of the World Friedreich's Ataxia | Not yet recruiting | Biogen | 40 | 2026-10-15 | 2026-10-21 | |
| Hypernatremia Fluid Therapy in Childhood Diarrhoea Oral rehydration solution (ORS) - Hypernatremia, Acute Watery Diarrhea | Not applicable | Enrolling by invitation | International Centre for Diarrhoeal Disease Research, Bangladesh | 268 | 2026-01-13 | 2026-10-21 |
| Assessment of Nutritional Status in Celiac Disease Using Muscle Ultrasound in Pediatric Patients. performing muscle ultrasonography on patients - Celiac Disease in Children, Nutritional Assessment | Not applicable | Enrolling by invitation | Ondokuz Mayıs University | 120 | 2026-08-03 | 2026-10-21 |
| Different Diets in Different Diabetes - 4DI PLAN'EAT Pilot Study Culturally adapted Mediterranean diet, Supervised walking programme, Standard dietary and behavioural counselling - Type 2 Diabetes | Not applicable | Active not recruiting | University of Bologna | 101 | 2024-06-03 | 2026-10-21 |
| HUGO-SLEEVE: Evaluating the Feasibility of Robotic Sleeve Gastrectomy With a New Platform Sleeve Gastrectomy using Hugo RAS platform - Obesity (BMI > 35), Obesity (BMI > 35) and Diabetes Mellitus | Not applicable | Recruiting | Universitätsklinikum Hamburg-Eppendorf | 50 | 2026-06-04 | 2026-10-21 |
| Study of Grape Consumption in Adaptation to Seasonal Photoperiod Freeze-Dried Grape Powder, Plain Low-Fat Yogurt, Mediterranean-Style Dietary Guidance - Metabolic Dysfunction-Associated Steatotic Liver Disease, Overweight | Not applicable | Active not recruiting | University Rovira i Virgili | 46 | 2026-09-28 | 2026-10-21 |
| Comprehensive Intervention to Promote Adjustment in Adolescents With Type 1 Diabetes and Their Parents During Transfer of Health Care Responsibility CONEXIÓN ADAPTAR - DM1, Usual Care - Type 1 Diabetes Mellitus (T1DM), Parent | Not applicable | Completed | Universidad de la Sabana | 34 | 2025-03-01 | 2026-10-21 |
| Hypoglycemia Risk Assessment in Elderly and Senile Female Patients With Type 2 Diabetes Mellitus Comprehensive Geriatric Assessment, Sarcopenia assessment, Laboratory assessment - Type 2 Diabetes Mellitus, Hypoglycemia | Completed | Samara State Medical University | 200 | 2020-01-01 | 2026-10-21 | |
| Efficacy and Safety of Modafinil to Treat Fatigue in People With Mitochondrial Disease. Modafinil (Placebo) - Mitochondrial Disease | Phase 3 | Not yet recruiting | Kenneth Myers, MD | 15 | 2026-12-01 | 2026-10-21 |
| Parkinson's Disease in Type 1 Gaucher Disease Parkinson Disease (PD), Type 1 Gaucher Disease | Recruiting | Icahn School of Medicine at Mount Sinai | 100 | 2026-10-01 | 2026-10-21 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Humanitarian Evaluation of Spatial Emanators for Malaria Control Guardian™ long-lasting spatial emanators - Malaria Infection | Phase 4 | Not yet recruiting | The Mentor Initiative | 32584 | 2026-10-26 | 2026-10-21 |
| A Clinical Study of AHB-121 in Healthy Participants and Chronic Hepatitis B (CHB) Participants AHB-121, Placebo - Chronic Hepatitis B Virus | Phase 1 | Not yet recruiting | Ausper Biopharma Co., Ltd. | 110 | 2026-10-28 | 2026-10-21 |
| Probiotic Supplement for Recurrent UTIs in Healthy Women (L. Plantarum, L. Rhamnosus, B. Lactis) Dietary Supplement containing probiotics, Placebo - Recurrent Urinary Tract Infections | Not applicable | Active not recruiting | Synbalance S.r.l. | 70 | 2026-10-14 | 2026-10-21 |
| Preoperative Pneumococcal and Influenza Vaccination to Prevent Postoperative Pulmonary Infection in Patients Undergoing Lung Resection for Pulmonary Nodules or Lung Cancer 23-valent pneumococcal polysaccharide vaccine, Quadrivalent split-virion influenza vaccine - Pneumococcal Polysaccharide Vaccine, Influenza Vaccines | Phase 4 | Not yet recruiting | The First Affiliated Hospital of Guangzhou Medical University | 1278 | 2026-11-01 | 2026-10-21 |
| Single-center, Open-label Study: Immunogenicity and Safety Observation After Vaccination With ACYW135 Meningococcal Polysaccharide Vaccine in Junior High School Students Aged 13-15 Years MPSV-ACYW - Meningococcal Disease; Meningococcal Meningitis | Phase 4 | Not yet recruiting | Zhejiang Provincial Center for Disease Control and Prevention | 200 | 2026-10-20 | 2026-10-21 |
| Fluoroquinolone-Doxycycline Oral Treatments for Adults With Uncomplicated Brucellosis Doxycycline + Rifampicin, Doxycycline + Levofloxacin, Doxycycline + Moxifloxacin - Brucellosis | Not applicable | Not yet recruiting | The First Affiliated Hospital of Shihezi University | 200 | 2026-11-01 | 2026-10-21 |
| VATS or Intrapleural Enzymatic Therapy for Patients With Empyema. VATS group, IET - Empyema, Pleural, Pleural Infections | Phase 4 | Not yet recruiting | Amsterdam UMC | 164 | 2026-10-01 | 2026-10-21 |
| Essential Oil Mouthwash - Oral Hygiene Essential oil mouthwash, Chlorhexidine gluconate alcohol-free mouthwash, Povidone-iodine alcohol-free mouthwash - Oral Hygiene, Oral Health, Dental Plaque | Not applicable | Completed | China Medical University, Taiwan | 150 | 2025-04-12 | 2026-10-21 |
| All-Oral Fluoroquinolone-Based Triple Therapies for Adults With Imaging-Confirmed Osteoarticular Brucellosis Doxycycline + Rifampicin + Ceftriaxone (intravenous therapy for 4 weeks), Triple oral regimen (Doxycycline + Rifampicin + Levofloxacin), Triple oral regimen (Doxycycline + Rifampicin + Moxifloxacin) - Brucellosis, Osteoarticular Brucellosis | Not applicable | Not yet recruiting | The First Affiliated Hospital of Shihezi University | 150 | 2026-11-01 | 2026-10-21 |
| Gamified Interactive Narrative (REPRO-QUEST) on Sexual Health Literacy and Sexually Transmitted Infection Prevention Behaviors REPRO-QUEST Interactive Narrative, Educational Booklet - Sexual Health, Sexually Transmitted Infection (STI) | Not applicable | Completed | Karamanoğlu Mehmetbey University | 82 | 2026-04-04 | 2026-10-21 |
| Channa Striata and Curcuma Domestica Supplementation in Patients With Active Pulmonary Tuberculosis CHANA STRIATA AND CURCUMA, Maltodextrin (Placebo) - Pulmonary Tuberculosis | Not applicable | Recruiting | DINA KEUMALA SARI | 80 | 2026-08-01 | 2026-10-21 |
| Perfusion Efficiency-Guided MAP De-escalation in Elderly Septic Shock Ascending MAP titration sequence, Descending MAP titration sequence - Sepsis | Not applicable | Not yet recruiting | Peking Union Medical College Hospital | 24 | 2026-11-01 | 2026-10-21 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Long-Term Safety and Tolerability of Nizubaglustat in Participants With Rare Lysosomal Disorders AZ-3102 - Niemann-Pick Disease Type C, GM2 Gangliosidosis | Phase 2 / Phase 3 | Not yet recruiting | Azafaros B.V. | 218 | 2026-12-10 | 2026-10-21 |
| Evaluation of ETHY-001 for Safety, Tolerability, and Clinical Activity in Thyroid Eye Disease ETHY-001, Placebo - Thyroid Eye Disease (TED), Graves' Disease | Phase 1 | Recruiting | Ethyreal Bio, Inc. | 72 | 2026-07-06 | 2026-10-21 |
| A Study of the Safety and Efficacy of Prime Editing (PM647a) in Participants With Alpha-1 Antitrypsin Deficiency PM647a - Alpha-1 Antitrypsin Deficiency, Alpha-1 Antitrypsin Deficiency-associated Lung Disease | Phase 1 / Phase 2 | Not yet recruiting | Prime Medicine, Inc. | 54 | 2026-10-01 | 2026-10-21 |
| A Study to Learn About the Study Medicine Abrocitinib in People With Severe Atopic Dermatitis Who Have Switched From Other Therapies abrocitinib - Dermatitis, Atopic | Not yet recruiting | Pfizer | 120 | 2026-10-01 | 2026-10-21 | |
| A Study to Learn More About Friedrich's Ataxia in People Living in the Gulf Cooperation Council (GCC) Region of the World Friedreich's Ataxia | Not yet recruiting | Biogen | 40 | 2026-10-15 | 2026-10-21 | |
| Combination Therapy With Danazol, Prednisolone, and Thalidomide for Thalidomide-Refractory Transfusion-Dependent β-Thalassemia Thalidomide, Danazol, Prednisolone - Beta-Thalassemia, Thalassemia | Phase 3 | Recruiting | Khyber Medical University Peshawar | 172 | 2026-10-12 | 2026-10-21 |
| Prevalence of Obstructive Sleep Apnea in HHT and HHT-specific Challenges in OSA-therapy - a Retrospective Cohort Study Hereditary Hemorrhagic Telangiectasia (HHT), Obstructive Sleep Apnea (OSA) | Not yet recruiting | University Hospital, Essen | 1000 | 2026-10-01 | 2026-10-21 | |
| PERCE-MUCO: Perceptions and Expectations of People With Cystic Fibrosis Regarding a Change in Treatment Cystic Fibrosis (CF) | Recruiting | Fondation Ildys | 343 | 2026-07-09 | 2026-10-21 | |
| Neonatal Outcomes on Direct Fetal Intravenous Immunoglobulin During Intrauterine Transfusion for Rhesus Isoimmunization Intrauterine Transfusion, Intravenous immunoglobulin (IVIG) - Hemolytic Disease of the Newborn, Fetal Anemia | Phase 2 | Recruiting | Post Graduate Institute of Medical Education and Research, Chandigarh | 30 | 2026-05-25 | 2026-10-21 |
| Clinical, Biochemical, and Cytogenetic Heterogeneity in Mosaic 46,XX/47,XXY Sex Chromosome Aneuploidy Klinefelter Syndrome (47, XXY), Sex Chromosome Aneuploidy | Completed | Université Paris-Saclay | 257 | 2022-01-15 | 2026-10-21 | |
| Parkinson's Disease in Type 1 Gaucher Disease Parkinson Disease (PD), Type 1 Gaucher Disease | Recruiting | Icahn School of Medicine at Mount Sinai | 100 | 2026-10-01 | 2026-10-21 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Trial to Evaluate Safety and Efficacy of Anitocabtagene Autoleucel Versus Standard of Care in Newly Diagnosed Multiple Myeloma Anitocabtagene autoleucel, Daratumumab, Bortezomib - Newly Diagnosed Multiple Myeloma | Phase 3 | Not yet recruiting | Kite, A Gilead Company | 600 | 2027-01-01 | 2026-10-21 |
| IBI3034 Study in Healthy Adults and Patients With Primary IgA Nephropathy IBI3034, Placebo, Telitacicept - IgA Nephropathy (IgAN) | Phase 1 | Not yet recruiting | Innovent Biologics (Suzhou) Co. Ltd. | 100 | 2026-10-15 | 2026-10-21 |
| Evaluation of ETHY-001 for Safety, Tolerability, and Clinical Activity in Thyroid Eye Disease ETHY-001, Placebo - Thyroid Eye Disease (TED), Graves' Disease | Phase 1 | Recruiting | Ethyreal Bio, Inc. | 72 | 2026-07-06 | 2026-10-21 |
| A Study Investigating the Safety and How the Trispecific T-Cell Engaging Antibody BG-T0920 Works in Adults With Diffuse Large B-cell Lymphoma (DLBCL) and Other Aggressive B-Cell Malignancies BG-T0920 - Diffuse Large B-Cell Lymphoma, B-cell Malignancies | Phase 1 | Not yet recruiting | BeOne Medicines | 70 | 2026-12-11 | 2026-10-21 |
| LAM-001 for the Treatment of Sarcoidosis Associated Pulmonary Hypertension (SAPH) Placebo, LAM-001 - Sarcoidosis Associated Pulmonary Hypertension | Phase 2 | Not yet recruiting | IRulya Therapeutics Inc. | 60 | 2026-12-01 | 2026-10-21 |
| REGN9220 in Combination With Odronextamab in Adult Participants With Relapsed or Refractory Aggressive B-Cell Non-Hodgkin Lymphomas (BCNHLs) REGN9220, Odronextamab - Diffuse Large B-Cell Lymphoma (DLBCL) | Phase 1 / Phase 2 | Not yet recruiting | Regeneron Pharmaceuticals | 36 | 2026-12-07 | 2026-10-21 |
| A Study to Learn About the Study Medicine Abrocitinib in People With Severe Atopic Dermatitis Who Have Switched From Other Therapies abrocitinib - Dermatitis, Atopic | Not yet recruiting | Pfizer | 120 | 2026-10-01 | 2026-10-21 | |
| Comprehensive Intervention to Promote Adjustment in Adolescents With Type 1 Diabetes and Their Parents During Transfer of Health Care Responsibility CONEXIÓN ADAPTAR - DM1, Usual Care - Type 1 Diabetes Mellitus (T1DM), Parent | Not applicable | Completed | Universidad de la Sabana | 34 | 2025-03-01 | 2026-10-21 |
| Neonatal Outcomes on Direct Fetal Intravenous Immunoglobulin During Intrauterine Transfusion for Rhesus Isoimmunization Intrauterine Transfusion, Intravenous immunoglobulin (IVIG) - Hemolytic Disease of the Newborn, Fetal Anemia | Phase 2 | Recruiting | Post Graduate Institute of Medical Education and Research, Chandigarh | 30 | 2026-05-25 | 2026-10-21 |
| Tacabrutideg and Sonrotoclax, With Response-Guided Obinutuzumab, for the Treatment of Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) Tacabrutideg, Sonrotoclax, Obinutuzumab - Chronic Lymphocytic Leukemia, Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma | Phase 2 | Not yet recruiting | Fred Hutchinson Cancer Center | 30 | 2027-01-01 | 2026-10-21 |
| A Randomized, Double-Blind, Placebo-Controlled Phase Ib Study of Multiple Ascending Doses of EB070 Injection in Adults With Moderate-to-Severe Asthma EB070 - Asthma | Phase 1 | Not yet recruiting | Biotech Pharmaceutical Co., Ltd. | 20 | 2026-09-30 | 2026-10-21 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Sleep MAPP in the Polytrauma/TBI System of Care Sleep MAPP Care Pathway - Insomnia Disorder, Mild Traumatic Brain Injury | Not applicable | Not yet recruiting | VA Office of Research and Development | 900 | 2027-01-01 | 2026-10-21 |
| Oral Care Program for Mouth Side Effects During Head and Neck Radiation Therapy ORAL CARE PRODUCT KIT - Head and Neck Cancer (H&N), Oral Mucositis (Ulcerative) Due to Radiation | Not applicable | Not yet recruiting | UNCANCER LLC | 50 | 2026-11-01 | 2026-10-21 |
| Comparing Surgical and Nonsurgical Outcomes of Tennis Elbow Conservative Arm, Surgical - Lateral Epicondylitis | Not applicable | Not yet recruiting | University of Pittsburgh | 200 | 2026-10-01 | 2026-10-21 |
| Nerve Block Resolution Time Display and Pain Complaints Physical display - Postoperative Pain, Rebound Pain | Not applicable | Not yet recruiting | Medical University of South Carolina | 128 | 2026-10-01 | 2026-10-21 |
| Adapalene Gel for Acute Radiation-Induced Skin Injury Adapalene gel 0.1%, Biafine topical emulsion - Dermatitis, Radiation-Induced, Adapalene | Early Phase 1 | Recruiting | Yunnan Cancer Hospital | 50 | 2026-03-01 | 2026-10-21 |
| Effects of Technology-Assisted Rehabilitation on Pain and Hand Function in People With Carpal Tunnel Syndrome Technology-Assisted Multimodal Rehabilitation Group (TARG), Conventional Physiotherapy Group (CPG) - Carpal Tunnel Syndrome (CTS) | Not applicable | Completed | Hüseyin Melih Göktuğ Akpulat | 40 | 2025-05-15 | 2026-10-21 |
| Functional Electrical Stimulation Combined With Exercise for Rotator Cuff-Related Shoulder Pain in Older Adults Functional electrical stimulation, Sham Functional Electrical Stimulation, Progressive Resistance Training - Rotator Cuff Disease, Subacromial Pain Syndrome | Not applicable | Recruiting | Lisa Griffin | 40 | 2025-10-01 | 2026-10-21 |
| Transcutaneous Spinal Cord Stimulation for Blood Pressure Augmentation Immediately After Spinal Cord Injury Spinal Cord Stimulation - Spinal Cord Injury Cervical, Spinal Cord Injuries (SCI) | Not applicable | Not yet recruiting | Markey Olson | 20 | 2026-12-01 | 2026-10-21 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Fasten Onco Digital Therapy During Neoadjuvant Treatment for Triple-Negative Breast Cancer Fasten Onco, Standard Neoadjuvant Treatment - Triple-Negative Breast Cancer (TNBC) | Not applicable | Not yet recruiting | FASTEN | 144 | 2026-10-30 | 2026-10-21 |
| A Study to Learn About the Study Medicine Abrocitinib in People With Severe Atopic Dermatitis Who Have Switched From Other Therapies abrocitinib - Dermatitis, Atopic | Not yet recruiting | Pfizer | 120 | 2026-10-01 | 2026-10-21 | |
| Definition of Novel Optoacoustic Biomarkers of Psoriasis and Psoriatic Arthritis Raster-Scan Optoacoustic Mesoscopy, Multispectral Optoacoustic Tomography, Skin Biopsy and Skin Sample Collection - Psoriasis (PsO), Psoriasis Arthritis | Not applicable | Not yet recruiting | University of Erlangen-Nürnberg Medical School | 192 | 2026-10-07 | 2026-10-21 |
| New Treatment in Melasma Tranexamic Acid - topical, Microneedling with Topical Tranexamic acid, Modified Kligman's Formula - Female, With | Not applicable | Not yet recruiting | Sohag University | 75 | 2026-10-18 | 2026-10-21 |
| Telerehabilitation-Supported Exercise in Women With Lipedema Telerehabilitation-Supported Exercise, Home Exercise Program - Lipedema | Not applicable | Not yet recruiting | Istanbul University | 66 | 2026-10-19 | 2026-10-21 |
| Adapalene Gel for Acute Radiation-Induced Skin Injury Adapalene gel 0.1%, Biafine topical emulsion - Dermatitis, Radiation-Induced, Adapalene | Early Phase 1 | Recruiting | Yunnan Cancer Hospital | 50 | 2026-03-01 | 2026-10-21 |
| Multimodal Respiratory Physiotherapy in Women Receiving Radiotherapy for Breast Cancer (RESPIRA-BC) Incentive Spirometry (IS) and Positive Expiratory Pressure (PEP) Training, Individualised Exercise Programme (Aerobic and Resistance Training), Patient Education Programme - Breast Neoplasms | Not applicable | Completed | University of Alcala | 22 | 2022-03-01 | 2026-10-21 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oral Care Program for Mouth Side Effects During Head and Neck Radiation Therapy ORAL CARE PRODUCT KIT - Head and Neck Cancer (H&N), Oral Mucositis (Ulcerative) Due to Radiation | Not applicable | Not yet recruiting | UNCANCER LLC | 50 | 2026-11-01 | 2026-10-21 |
| Essential Oil Mouthwash - Oral Hygiene Essential oil mouthwash, Chlorhexidine gluconate alcohol-free mouthwash, Povidone-iodine alcohol-free mouthwash - Oral Hygiene, Oral Health, Dental Plaque | Not applicable | Completed | China Medical University, Taiwan | 150 | 2025-04-12 | 2026-10-21 |
| Photobiomodulation After Nonsurgical Root Canal Treatment Adjunctive Photobiomodulation, Sham Photobiomodulation - Symptomatic Apical Periodontitis, Postoperative Pain | Not applicable | Not yet recruiting | University of Minnesota | 60 | 2026-10-19 | 2026-10-21 |
| Comparison of Two Dental Implant Types and Placement Depths on Bone Around the Implant in Adults Missing Back Teeth issue-level implant placed at crestal level (Klockner Essential Cone), Bone-level implant placed 2 mm subcrestally with one-abutment-one-time protocol (Klockner Vega) - Partial Edentulism, Dental Implants | Not applicable | Completed | Markel Diéguez-Pereira | 30 | 2022-05-02 | 2026-10-21 |
| Antibiotic Resistance Genes in Periodontitis Periodontal Disease, Periodontitis | Active not recruiting | Istanbul University | 50 | 2026-02-24 | 2026-10-21 | |
| Color Stability of Darkly Discolored Arrested Caries Lesions Following Bleaching Treatment Dental Caries, Tooth Discoloration | Completed | Selcuk University | 27 | 2023-02-10 | 2026-10-21 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Low-Dose Radiotherapy for Painful Knee Osteoarthritis Low-Dose Radiotherapy (LDRT) - Knee Osteoarthritis | Not applicable | Not yet recruiting | Universidad Rey Juan Carlos | 283 | 2026-10-15 | 2026-10-21 |
| Comparing Surgical and Nonsurgical Outcomes of Tennis Elbow Conservative Arm, Surgical - Lateral Epicondylitis | Not applicable | Not yet recruiting | University of Pittsburgh | 200 | 2026-10-01 | 2026-10-21 |
| Effects of Respiratory Muscle Strengthening and Diaphragmatic Breathing on Shoulder Pain and Disability shoulder rehabilitation, respiratory muscle strengthening exercises and diaphragmatic breathing exercises - Shoulder Pain, Sleep Quality | Not applicable | Recruiting | Zonguldak Bulent Ecevit University | 70 | 2025-11-25 | 2026-10-21 |
| Functional Electrical Stimulation Combined With Exercise for Rotator Cuff-Related Shoulder Pain in Older Adults Functional electrical stimulation, Sham Functional Electrical Stimulation, Progressive Resistance Training - Rotator Cuff Disease, Subacromial Pain Syndrome | Not applicable | Recruiting | Lisa Griffin | 40 | 2025-10-01 | 2026-10-21 |
| Comparison of Two Dental Implant Types and Placement Depths on Bone Around the Implant in Adults Missing Back Teeth issue-level implant placed at crestal level (Klockner Essential Cone), Bone-level implant placed 2 mm subcrestally with one-abutment-one-time protocol (Klockner Vega) - Partial Edentulism, Dental Implants | Not applicable | Completed | Markel Diéguez-Pereira | 30 | 2022-05-02 | 2026-10-21 |
| Recurrence of Extremity Joint Contracture After Z-Plasty Versus Full-Thickness Skin Graft Z-Plasty, Full-Thickness Skin Graft - Joint Contracture, Contracture | Not yet recruiting | Universitas Sebelas Maret | 300 | 2026-10-13 | 2026-10-21 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of ETHY-001 for Safety, Tolerability, and Clinical Activity in Thyroid Eye Disease ETHY-001, Placebo - Thyroid Eye Disease (TED), Graves' Disease | Phase 1 | Recruiting | Ethyreal Bio, Inc. | 72 | 2026-07-06 | 2026-10-21 |
| Prevalence of Age-Related Macular Degeneration in Assiut University Hospitals OCT - clear - Age-Related Macular Degeneration (AMD) | Not yet recruiting | Assiut University | 90 | 2027-01-01 | 2026-10-21 | |
| Ocular Fluid Work-up in Presumed Trematode Induced Granulomatous Uveitis AC fluid sample, Vitreous fluid sample - Presumed Trematode Induced Uveitis, Uveitis | Recruiting | Kasr El Aini Hospital | 40 | 2026-09-01 | 2026-10-21 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Deep Repetitive Transcranial Magnetic Stimulation in the Treatment of Tinnitus DeepTms - Tinnitus, Tinnitus, Bilateral | Not applicable | Recruiting | University of Regensburg | 60 | 2026-09-19 | 2026-10-21 |
| Effects of Myofascial Release on Postural Balance and Cervical Muscle Function in Benign Paroxysmal Positional Vertigo Home-Based Balance Exercise Program, Myofascial Release Therapy - Benign Paroxysmal Positional Vertigo | Not applicable | Completed | Karabuk University | 40 | 2021-09-01 | 2026-10-21 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Learn About Revaccination With a Vaccine Called RSVpreF in Older Adults RSVpreF (Regimen A), RSVpreF (Regimen B) - Respiratory Syncytial Virus (RSV) | Phase 3 | Not yet recruiting | Pfizer | 750 | 2026-10-29 | 2026-10-21 |
| iLITE, Clinical Performance of the Angiolite™ Drug-Eluting Stent Percutaneous Coronary Intervention - PCI Patients, de Novo Coronary Lesions | Not yet recruiting | iVascular S.L.U. | 5000 | 2026-10-01 | 2026-10-21 | |
| Cefepime-Zidebactam Versus Ceftazidime-Avibactam With or Without Colistin for Hospital-Acquired or Ventilator-Associated Bacterial Pneumonia Cefepime-Zidebactam, Ceftazidime-avibactam with or without Colistin - Hospital Acquired Bacterial Pneumonia (HABP), Ventilator Associated Bacterial Pneumonia (VABP) | Phase 3 | Not yet recruiting | Wockhardt | 324 | 2026-10-28 | 2026-10-21 |
| A Clinical Trial to Test if the Investigational Drug BNT3210 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker Sialyl-Tn BNT3210 - Advanced Solid Tumors | Phase 1 / Phase 2 | Not yet recruiting | BioNTech SE | 173 | 2026-11-01 | 2026-10-21 |
| Effects of Probiotics on Skin Health in Healthy Women Probiotics, Placebo - Skin Aging, Dry Skin | Not applicable | Not yet recruiting | Probi AB | 140 | 2026-10-01 | 2026-10-21 |
| MagSense® Human Epidermal Growth Factor Receptor 2 (HER2) Imaging Agent (MSH2IA) The MagSense® HER2 Imaging Agent (MSH2IA) - HER2-positive Breast Cancer | Phase 1 / Phase 2 | Not yet recruiting | Imagion Biosystems, Inc. | 70 | 2026-11-30 | 2026-10-21 |
| A Phase 1 Study to Evaluate Safety, Tolerability, and Drug Levels of BMS-986485 in Healthy Adult Participants BMS-986485, BMS-986485 matching placebo - Healthy Volunteers | Phase 1 | Not yet recruiting | Bristol-Myers Squibb | 50 | 2026-11-03 | 2026-10-21 |
| Study of the Safety, Tolerability, Pharmacokinetics of VV147 Tablets in Chinese Healthy Participants. VV147 15mg Group, VV147 30mg Group, VV147 60mg Group - Healthy Participants | Phase 1 | Not yet recruiting | Vigonvita Life Sciences | 48 | 2026-10-20 | 2026-10-21 |
| Corneal Trauma Diagnostic Study Tear fluid collection with mass spec analysis. - Ocular Trauma | Not applicable | Recruiting | InnSight Technology, Inc. | 40 | 2026-11-01 | 2026-10-21 |
| Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Recombinant Anfibatide Injection in Healthy Volunteers Recombinant Anfibatide Injection, Placebo - Healthy Volunteers | Phase 1 | Not yet recruiting | Lee's Pharmaceutical Limited | 36 | 2026-11-30 | 2026-10-21 |
| A Study to Evaluate the Effect of Carbamazepine or Itraconazole on Radiprodil in Healthy Adult Participants Radiprodil, Carbamazepine, Itraconazole (200 mg) - Healthy Adult Participants | Phase 1 | Active not recruiting | GRIN Therapeutics, Inc. | 36 | 2026-06-08 | 2026-10-21 |
| A Study to Evaluate the Efficacy and Safety of TP-06 for PCED TP-06, Vehicle of TP-06 - Persistent Corneal Epithelial Defect | Phase 2 | Recruiting | Tarsus Pharmaceuticals, Inc. | 32 | 2026-04-20 | 2026-10-21 |
| Safety and Tolerability of AT-0174 in Adults With Advanced Solid Tumors AT-0174 - Advanced Solid Tumor | Phase 1 | Completed | Antido Therapeutics (Australia) Pty Ltd | 26 | 2023-11-15 | 2026-10-21 |
| NUS Health Study: Improving Sleep, Sedentariness and Physical Activity in NUS Staff NUS Health Prog - Focused Strategies to Optimize Sleep, Reduce Sedentary Behaviour, and Enhance Incidental Physical Activity | Not applicable | Recruiting | National University of Singapore | 2000 | 2026-09-01 | 2026-10-21 |
| Firearm Secure Storage Device Distribution RCT Cable locks, Lock box, Lock box and cable locks - Firearm Safety, Firearm Safety Storage | Not applicable | Not yet recruiting | University of Pennsylvania | 1858 | 2026-10-21 | 2026-10-21 |
| Differential Absorption Kinetics of Grape Seed Extract Polyphenols MN-BP Grape Seed Extract, Commercially Available Grape Seed Extract, Gen 2 GSE - Monomer-Enriched - Healthy Adults | Not applicable | Not yet recruiting | Clinical Nutrition Research Center, Illinois Institute of Technology | 10 | 2026-10-20 | 2026-10-21 |
| Corrective Multisport Training Corrective multisport training - Postural Alignment | Not applicable | Completed | University of Novi Sad | 398 | 2021-09-01 | 2026-10-21 |
| Driving Pressure-Guided Individualized PEEP Versus Standard PEEP: Effects on Postoperative Pulmonary Complications in Upper Abdominal Digestive Surgery Driving Pressure-Guided Individualized PEEP, Standard PEEP - Postoperative Pulmonary Complications, Mechanical Ventilation | Not applicable | Recruiting | Hopital Charles Nicolle | 210 | 2026-05-22 | 2026-10-21 |
| Diode Laser Added to Non-Surgical Treatment for Peri-Implant Mucositis Conventional Non-Surgical Treatment, Adjunctive Diode Laser Therapy - Peri-implant Mucositis | Not applicable | Completed | Universidad Europea de Valencia | 206 | 2022-01-26 | 2026-10-21 |
| A Prospective Multicenter Registry Study of Sedation and Analgesia in Critically Ill Patients Not applicable- observational study - Sedation, Analgesia Assessment | Enrolling by invitation | Beijing Chao Yang Hospital | 2000 | 2027-01-01 | 2026-10-21 | |
| Airway Survey - International Airway Assessment Practices (2023-2028) Structured Survey on Preoperative Airway Assessment - Airway Assessment | Not yet recruiting | Johannes Gutenberg University Mainz | 2000 | 2026-11-01 | 2026-10-21 | |
| Evaluation of Interventions to Promote Work-Life Balance Among Students at Gaming Schools Online health promotion interventions for gaming school students, In person health promotion interventions for gaming school students - Internet Gaming Disorder | Not applicable | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 200 | 2027-01-01 | 2026-10-21 |
| Comparison of Postoperative Pain After Root Canal Treatment Using Hand-Held vs Rotary ProTaper Files: A Randomized Controlled Trial ProTaper Manual Root Canal Instrumentation, ProTaper Rotary Root Canal Instrumentation - Symptomatic Irreversible Pulpitis (SIP), Symptomatic Apical Periodontitis | Not applicable | Not yet recruiting | College of Physicians and Surgeons Pakistan | 200 | 2026-12-05 | 2026-10-21 |
| Impact of Functional Rehabilitation on Digital Independence: Validation of a Novel Smartphone Use Score as an Indicator of Discharge Readiness in Medical Care and Rehabilitation. TSHN-SMR (Test Standardisé d'Habileté Numérique sur Dispositif Dédié), Barthel scale - Medical Rehabilitation | Not applicable | Not yet recruiting | Artois Private Hospital | 150 | 2026-10-30 | 2026-10-21 |
| Three-dimensional Biomechanics of the Lower Limbs in Healthy Volunteers: Establishment of a Reference Database Using the MERItest® System MERITest - Healthy Adult Participants, Anterior Cruciate Ligament (ACL) | Not applicable | Not yet recruiting | Clinique du Sport, Bordeaux Mérignac | 150 | 2026-10-15 | 2026-10-21 |
| Comparing the Effect of Scenario-Based Teaching Method to Conventional Method on Medical Students' Knowledge and Satisfaction in Psychiatry Interns scenario-based teaching method - Knowledge, Satisfaction | Not applicable | Active not recruiting | Mashhad University of Medical Sciences | 132 | 2025-10-21 | 2026-10-21 |
| RGE-Based Cell Physiology Education for International Medical Students RGE-Based Cell Physiology Education - Cell Physiology Education | Not applicable | Completed | Tehran University of Medical Sciences | 128 | 2024-11-04 | 2026-10-21 |
| Chatbot Utilization for Pedigree Creation and Cancer Risk Assessment in Cancer Genetic Counseling Text Message -based Navigation Intervenion, Artificial Intelligence based Intervention - Hereditary Breast Carcinoma, Hereditary Malignant Neoplasm | Not applicable | Not yet recruiting | Roswell Park Cancer Institute | 129 | 2026-11-01 | 2026-10-21 |
| Post Pulmonary Embolism In Patients Treated With Catheter Based Therapy The Indigo aspiration system - Pulmonary Embolism Acute | Not applicable | Not yet recruiting | Assiut University | 120 | 2026-12-01 | 2026-10-21 |
| Jigsaw and Audience Response System for Arterial Blood Gas Education Jigsaw Cooperative Learning, Kahoot-Based Audience Response System - Nursing Education | Not applicable | Not yet recruiting | Bilecik Seyh Edebali Universitesi | 110 | 2026-10-30 | 2026-10-21 |
| The Effect of Virtual Reality-Based Disaster Training on Disaster Readiness of Health Science Students simulations Virtual Reality-Based Disaster Training With Simulation - Disaster Readiness Among Health Science Students | Not applicable | Completed | Vision College - Riyad | 110 | 2026-04-01 | 2026-10-21 |
| Implicit Bias in Intensive Care: Analysis and Assessment. Intensive Care | Not yet recruiting | University Hospital, Bordeaux | 1000 | 2026-12-01 | 2026-10-21 | |
| EMI for Reducing Psychological Distress in Young Adults With Multiple ACEs: A RCT Study EMI - Psychological Distress, Adverse Childhood Experience | Not applicable | Not yet recruiting | Peking University | 100 | 2026-10-19 | 2026-10-21 |
| THE EFFECT OF A TRANSTHEORETICAL MODEL-BASED CHATBOT SUPPORT INTERVENTION ON SMOKING BEHAVIOR IN UNIVERSITY STUDENTS Dumansız (Transtheoretical Model-Based Chatbot Support Intervention) - Smoking ( Cigarette), Smoking (Tobacco) Addiction | Not applicable | Active not recruiting | Seher DÖNER | 100 | 2026-06-25 | 2026-10-21 |
| RWS of PDT for CIN 2 Hexaminolevulinate (HAL) - Cervical Intraepithelial Neoplasia Grade 2 (CIN2) | Not yet recruiting | Tongji Hospital | 1000 | 2028-06-01 | 2026-10-21 | |
| The Effects of a Scenario-based Fact-checking Course on eHealth Literacy and Fact-checking Skills Among Older Adults. Scenario-Based Fact-Checking Course, Nutrition Education - eHealth Literacy, Digital Health Literacy | Not applicable | Not yet recruiting | National Yang Ming Chiao Tung University | 100 | 2026-09-01 | 2026-10-21 |
| Counter Bias Training Simulation Healthcare CBTsim, bias documentary - Implicit Bias | Not applicable | Completed | Washington State University | 91 | 2025-11-05 | 2026-10-21 |
| Effects of Immersive VR, Non-Immersive VR, and 3D-Printed Models on Anatomy Learning and Cognitive Load Immersive Virtual Reality Experience, Non-Immersive Virtual Reality Experience, 3D printed model Experience - Healthy, Health Knowledge, Attitudes, Practice | Not applicable | Not yet recruiting | Abant Izzet Baysal University | 90 | 2026-10-01 | 2026-10-21 |
| Attitudes, Experience and Adaptation to Family Presence in the ICU questionnaire - ICU Staff Attitudes Toward Family Presence, ICU Staff Experience of Family Presence | Not applicable | Enrolling by invitation | Universitair Ziekenhuis Brussel | 80 | 2026-09-29 | 2026-10-21 |
| 68Ga-XHER2 PET/CT for HER2 Assessment 68Ga-XHER2 PET/CT - Solid Tumor (Excluding CNS), HER2 | Not applicable | Recruiting | The First Affiliated Hospital of Xiamen University | 80 | 2026-10-22 | 2026-10-21 |
| Comparison of Escape Room and Branching Scenario Games in Nursing Education EQUITY-ROOM (Web-based Escape Room Game), EQUITY-PATH (Web-based Branching Scenario Game), Standardized Video-Based Education - Gender Prediction, Dating Violence | Not applicable | Not yet recruiting | Karamanoğlu Mehmetbey University | 72 | 2026-10-01 | 2026-10-21 |
| Visual Feedback-Assisted Sensorimotor Training in Chronic Nonspecific Low Back Pain Visual Feedback-Assisted Sensorimotor Training, Conventional Exercise Training - Chronic Low Back Pain | Not applicable | Not yet recruiting | Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital | 70 | 2026-11-15 | 2026-10-21 |
| The Impact of Early-life Organic Feeding on Infants' Health: A Cluster Randomized Controlled Trial Organic infant formula and organic complementary foods, Conventional infant formula and conventional complementary foods - Infant Growth and Development, Gut Microbiota | Not applicable | Completed | Tsinghua University | 71 | 2022-04-22 | 2026-10-21 |
| Study on the Impact of Different Feeding Methods on Allergy Prevention and Digestive Absorption in Infants and Young Children：A Mixed Study Observation, biological sample collection: stool - This Study Focused on the Incidence of Infant Allergy and Various Disease, Supported by Data on 16S rRNA Gut Microbiota and Untargeted Metabolomicsolome | Active not recruiting | Tsinghua University | 696 | 2026-03-01 | 2026-10-21 | |
| The Effect of Structured Therapeutic Play Program on Aggression, Social Emotional Well-Being and Psychological Resilience in Preschool Children Structured Play Activity in Preschool Children - Psychological Resilience | Not applicable | Completed | Cumhuriyet University | 68 | 2023-10-20 | 2026-10-21 |
| Evaluation of the Statistical Validity of Cervical Spine Measurements-Including Range of Motion, Strength, and Functional Test Results-for Return to Sport in Patients Who Have Undergone Surgery for Cervical Stenosis and/or Herniation. Questionnaires, Physical tests - Cervical Stenosis, Cervical Spine | Not applicable | Recruiting | GCS Ramsay Santé pour l'Enseignement et la Recherche | 60 | 2022-07-19 | 2026-10-21 |
| Postoperative Pain and Quality of Life Following Root Canal Treatment With Two Different Sealers AH Plus, BioRoot Flow - Asymptomatic Apical Periodontitis | Not applicable | Completed | Karadeniz Technical University | 58 | 2026-04-01 | 2026-10-21 |
| Acute Effects of Stretching, Kinesio Taping, Cold Water Immersion and Foam Rolling on Wrist Strength and Precise Force and Position Control Static stretching, Assisted dynamic stretching, Kinesio taping - Healthy Volunteers, Muscle Strength | Not applicable | Completed | Grgur Kovačić | 56 | 2022-04-04 | 2026-10-21 |
| Prediction of Difficult Mask Ventilation in Obese Population Undergoing Emergency Surgery Difficult Airway Management | Not yet recruiting | Minia University | 550 | 2026-10-15 | 2026-10-21 | |
| Sphenopalatine Ganglion Block Combined With Either Scalp Nerve Block or Local Wound Infiltration for Postoperative Analgesia in Adult Patients Undergoing Craniotomy: A Randomized Controlled Trial Group (c): control group patients will receive general anesthesia., Group (SS): Sphenopalatine Ganglion Block with either Scalp Nerve Block, Group (SL): patients will receive Sphenopalatine Ganglion Block with local wound infiltration - Craniotomy Surgery | Not applicable | Not yet recruiting | Zagazig University | 54 | 2026-10-30 | 2026-10-21 |
| Comparative Study Between Proprioceptive Neuromuscular Facilitation and Post-facilitation Stretching in Text Neck Syndrome Proprioceptive Neuromuscular Facilitation, Post-facilitation Stretching, traditional treatment - Text Neck Syndrome | Not applicable | Not yet recruiting | Cairo University | 51 | 2026-10-27 | 2026-10-21 |
| The Microbiome in Uveitis and Pediatric Inflammatory Diseases Noninfectious Uveitis | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 500 | 2026-11-01 | 2026-10-21 | |
| Jaktinib for Steroid-Refractory Acute Graft-Versus-Host Disease Jaktinib - Acute Graft vs Host Disease | Phase 1 / Phase 2 | Not yet recruiting | Nanfang Hospital, Southern Medical University | 49 | 2026-10-10 | 2026-10-21 |
| Gamified Versus Regular Exercise Snacks on Stationary Bikes, as One 10-Minute or Two 5-Minute Sessions a Day, for Children in an Inclusive Primary School Stationary cycling with game display, Stationary cycling with regular display, One 10-minute ride per riding day - Exercise, Sedentary Behavior | Not applicable | Not yet recruiting | Macao Polytechnic University | 48 | 2026-10-19 | 2026-10-21 |
| Comparative Assessment of Marginal Bone Loss Around the Implant When Using PEEK With Composite Veneering Versus Monolithic Zirconia Restorations as Implant Restorations PEEK (Polyetheretherketone) screw-retained implant restoration veneered with composite, Monolithic zirconia screw-retained implant restoration - Partial Edentulism Class IV | Not applicable | Completed | Cairo University | 48 | 2025-04-10 | 2026-10-21 |
| Four Different Guided Bone Regeneration Strategies for Horizontal Ridge Augmentation in the Maxillary Esthetic Zone With Simultaneous Implant Placement: a Randomized Clinical Trial Titanium Mesh-Guided Bone Regeneration, Extended Sticky Bone Augmentation, Medpark Bone Graft Augmentation - Horizontal Alveolar Ridge Augmentation | Not applicable | Completed | Mansoura University | 40 | 2025-09-01 | 2026-10-21 |
| Functional Biomechanical Analysis in Patients Who Underwent Lateral Ankle Ligament Repair With Augmentation Biomechanical motion analysis - Chronic Lateral Ankle Instability | Not applicable | Recruiting | Clinique du Sport, Bordeaux Mérignac | 39 | 2026-10-20 | 2026-10-21 |
| Effects of Instrument-Assisted Soft Tissue Mobilization Versus Post Facilitation Stretch Technique in Chronic Neck Pain Instrument Assisted Soft Tissue Mobilization, Post Facilitation Stretch - Cerival Pain, Chronic Neck Pain | Not applicable | Recruiting | Foundation University Islamabad | 38 | 2026-02-12 | 2026-10-21 |
| NEURO-IS: Neurophysiology of Inner Speech Across Neurotypical Participants. Inner Experience Induction Tasks and hdEEG - Healthy Volunteer, Inner Speech | Not applicable | Recruiting | University of Liege | 35 | 2026-10-05 | 2026-10-21 |
| Computed Inspiratory Muscle Pressure to Monitor Inspiratory Effort During Pressure Support Ventilation Pressure support 15, Pressure support 13, Pressure support 11 - Mechanical Ventilation, Critical Care | Not applicable | Not yet recruiting | Jian-Xin Zhou | 30 | 2026-11-01 | 2026-10-21 |
| Comparing Two Techniques to Treat Gummy Smile Patients: Flapless Piezo-surgery Versus Conventional Open Flap Surgery. piezo-electric surgery, conventional open flap crown lengthening - Altered Passive Eruption | Not applicable | Completed | Suez Canal University | 30 | 2023-02-11 | 2026-10-21 |
| Computed Inspiratory Muscle Pressure to Monitor Inspiratory Effort During Pressure-Targeted Assist/Control Ventilation Positive end-expiratory pressure 11, Positive end-expiratory pressure 9, Positive end-expiratory pressure 7 - Mechanical Ventilation, Critical Care | Not applicable | Not yet recruiting | Jian-Xin Zhou | 30 | 2026-11-01 | 2026-10-21 |
| Testing a Smartphone App to Support a Mediterranean Diet and Strength Exercise MedEx Tracker, Printed dietary and resistance exercise programme - Treatment Adherence and Compliance, Resistance Exercise | Not applicable | Not yet recruiting | Liverpool John Moores University | 30 | 2026-10-01 | 2026-10-21 |
| Effects of Tart Cherry and Aronia Extract Supplementation on Selected Physiological Parameters in Endurance-Trained Men Standardized Tart Cherry and Aronia Extract, Placebo - Cardiovascular Physiology | Not applicable | Not yet recruiting | Wroclaw Medical University | 25 | 2026-10-10 | 2026-10-21 |
| Effects of FIFA 11+ Warm-Up Program on Motor Performance in Young Soccer Players FIFA 11+ Program, Traditional Warm-Up - Athletic Performance, Physical Fitness | Not applicable | Completed | Istanbul Gelisim University | 24 | 2025-05-20 | 2026-10-21 |
| The Effects of Interval Respiratory Muscle Training on Athletic Performance IMT %40 MIP, IMT %50-60-70-80 - Respiratory Muscle Training, Inspiratory Muscle Strength | Not applicable | Completed | Ondokuz Mayıs University | 23 | 2024-09-15 | 2026-10-21 |
| REVIVE-FR Registry TAVI-in-SAVR (Valve-in-Valve), THV-in-THV (Redo-TAVI), Surgical Explantation of a Failed Transcatheter Heart Valve - Bioprosthetic Valve Failure, Prosthetic Heart Valve Dysfunction | Not yet recruiting | Institut für Pharmakologie und Präventive Medizin | 200 | 2027-03-15 | 2026-10-21 | |
| Antimicrobial Resistance and Genomic Profiling of Bacterial Isolates Identification of bacterial isolates causing blood stream infection and determination of their antibiotic sensitivity, Molecular characterization of bacterial isolates - Blood Stream Infections, Adult Cancer Patients | Not yet recruiting | Sohag University | 200 | 2026-11-01 | 2026-10-21 | |
| Turkish Adaptation of the Perceived Barriers to Exercise Questionnaire for Office Workers Perceived Barriers to Exercise | Not yet recruiting | Istinye University | 200 | 2026-10-25 | 2026-10-21 | |
| Comparison of the Effects of Ciprofol and Propofol on Cognitive Function After Painless Gastroenteroscopy Ciprofol - Neurocognitive Function | Completed | Second Affiliated Hospital of Wenzhou Medical University | 196 | 2025-07-01 | 2026-10-21 | |
| NRI: Robot-Assisted Longitudinal Physical and Cognitive Exercise Interventions for Older Veterans Exercise with Assistive Robot - Active Control (Robot on Screen), Adaptive Assistive Robot | Early Phase 1 | Active not recruiting | Oregon State University | 12 | 2026-07-08 | 2026-10-21 |
| Assessment of the Degree of Regeneration After Partial Meniscectomy Based on Thin-layer MRI Image Segmentation and Reconstruction No intervention measures. - Meniscus Regeneration, Partial Meniscectomy | Recruiting | Beijing Tsinghua Chang Gung Hospital | 120 | 2024-01-01 | 2026-10-21 | |
| Customized CBCT-Based Assessment of Transverse Discrepancies Transverse Skeletal Discrepancy | Active not recruiting | October University for Modern Sciences and Arts | 120 | 2026-09-01 | 2026-10-21 | |
| Flap Assessment With Regional Oximetry for Early Detection of Compromise in Free Flap Reconstructive Surgery - FLARE Study Elective free flap surgery, INVOS monitoring - Reconstructive Surgery, Flap Monitoring | Not yet recruiting | Leiden University Medical Center | 100 | 2026-12-01 | 2026-10-21 | |
| Detecting Early Weaning-induced Pulmonary Oedema Using Lung Impedance Negative Trend During SBT Weaning-induced Pulmonary Edema, Mechanical Ventilation Weaning | Not yet recruiting | Unity Health Toronto | 89 | 2026-11-01 | 2026-10-21 | |
| Serum and Salivary Leptin Levels in Children With Adenoid/Adenotonsillar Hypertrophy Blood and saliva sampling - Adenoid Hypertrophy, Adenotonsillar Hypertrophy | Recruiting | Harran University | 80 | 2026-03-02 | 2026-10-21 | |
| Open Versus Fully Endoscopic Calcaneoplasty With Achilles Tendon Insertional Reconstruction for Haglund Syndrome Haglund Syndrome, Insertional Achilles Tendinopathy | Not yet recruiting | Nanjing First Hospital, Nanjing Medical University | 67 | 2026-11-01 | 2026-10-21 | |
| Plantar Fascia Thickness and Pedobarometric Parameters in Sacroiliac Joint Dysfunction Sacroiliac Joint Dysfunction, Plantar Fascia Thickness | Completed | Dokuz Eylul University | 52 | 2026-03-02 | 2026-10-21 | |
| Long-Term Cognitive Recovery After Arteria Cerebri Media Ischemia: A Digital Assessment Using the TuCAN-App Cognitive Recovery After Stroke, Cognitive Outcome After Stroke | Recruiting | University Hospital Tuebingen | 50 | 2025-07-01 | 2026-10-21 | |
| Effect of Methotrexate on Blood Loss During Laparoscopic Management of CS Scar Pregnancy Cesarean Scar Pregnancy | Not yet recruiting | Assiut University | 42 | 2026-10-15 | 2026-10-21 | |
| What Should we Measure? A Qualitative Interview Study on Outcomes for Evaluating AI-assisted Medical Image Interpretation. Artificial Intelligence Perception and Attitude | Enrolling by invitation | University of Oxford | 30 | 2026-10-16 | 2026-10-21 | |
| Evaluation of a Point-of-Care, AI-Powered Spectroscopy Device for Triage of Suspicious Vulvar Lesions: A Pilot Study Non-Interventional Study - Vulvar Intraepithelial Neoplasia, HPV-Independent, Vulvar Squamous Cell Carcinoma | Recruiting | Mayo Clinic | 20 | 2026-10-06 | 2026-10-21 | |
| Anesthesia Management and Perioperative Outcomes in Awake Jejunostomy and Gastrostomy Jejunostomy, Gastrostomy | Completed | Samsun University | 16 | 2024-02-01 | 2026-10-21 | |
| Effects of Trendelenburg Position and Pneumoperitoneum on Mechanical Power and Respiratory Mechanics During V-NOTES Surgery Respiratory Mechanics During vNOTES Surgery | Not yet recruiting | Burcu Ayvazoğlu | 14 | 2026-10-15 | 2026-10-21 | |
| [Trial of device that is not approved or cleared by the U.S. FDA] | Withheld | [Redacted] | 2026-10-21 | |||
| [Trial of device that is not approved or cleared by the U.S. FDA] | Withheld | [Redacted] | 2026-10-21 |
Trials whose results were posted on ClinicalTrials.gov between 2026-10-16 to 2026-10-22.
| Trial | Posted | Phase | Sponsor |
|---|---|---|---|
| Building Resilience and Appropriate Independence in Young Adults With Autism Life Skills and Resilience Program | 2026-10-21 | Not applicable | University of California, San Francisco |
| Connect TF - An Investigation of Function and Usability of a New Adaptable Socket System CONNECT TF adaptable socket system, Any conventional handmade socket | 2026-10-21 | Not applicable | Össur Iceland ehf |
| Switching Individuals in Treatment for Opioid Use Disorder Who Smoke Cigarettes to the SREC Standardized research e-cigarette (SREC) | 2026-10-21 | Not applicable | Massachusetts General Hospital |
| Neurofeedback During Naturalistic Stimuli to Reduce Craving in Heroin Addiction Real-time fMRI Neurofeedback, Sham Real-time fMRI Neurofeedback | 2026-10-21 | Not applicable | Icahn School of Medicine at Mount Sinai |
| A Study to Evaluate the Efficacy and Safety of CBL-514 in Participants With EFP; Cellulite (Stage 1) 40 mg CBL-514, 60 mg CBL-514, 80 mg CBL-514 | 2026-10-21 | Phase 2 | Caliway Biopharmaceuticals Co., Ltd. |
| To Assess the Safety and Tolerability of Tafasitamab Alone or in Combination With Other Drugs in Japanese Participants With Non-Hodgkins Lymphoma (NHL) tafasitamab, lenalidomide, parsaclisib | 2026-10-21 | Phase 1 / Phase 2 | Incyte Biosciences Japan GK |
| Optical Coherence Tomography Guided Laser Treatment of Basal Cell Carcinoma 1064 nm long-pulse Nd:YAG laser | 2026-10-21 | Not applicable | Christopher Zachary |
| Intravenous Methadone Versus Intrathecal Morphine for Analgesia Following Cesarean Delivery Intravenous line (IV) Methadone, Intrathecal Morphine | 2026-10-21 | Phase 4 | Mayo Clinic |
| Effects of Sleep Disruption on Drug Response Within-Subject test of blinded study medication | 2026-10-21 | Phase 2 | Johns Hopkins University |
| Sorafenib Induced Autophagy Using Hydroxychloroquine in Hepatocellular Cancer Sorafenib (SOR), Hydroxychloroquine (HCQ) | 2026-10-21 | Phase 2 | The University of Texas Health Science Center at San Antonio |
| FOLFIRINOX With Digoxin in Patients With Resectable Pancreatic Cancer Digoxin, 5Fluorouracil, Calcium Leucovorin | 2026-10-21 | Phase 2 | University of Nebraska |
| Randomized Evaluation of Patients Who Have Had Laparoscopic Partial Nephrectomy Hemostatic Agent, No Hemostatic Agent | 2026-10-21 | Not applicable | University of Chicago |
| Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax in Combination With Intravenous (IV) Obinutuzumab or Oral Ibrutinib in Adult Participants With Untreated Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) Venetoclax, Ibrutinib, Obinutuzumab | 2026-10-21 | Phase 2 | AbbVie |
| This Study Will Collect Clinical and Patient Reported Satisfaction Data From Males Requiring Urine Output Management Overnight in the Home Setting. PureWick® Urine Collection System, UltraFlex™ Self-Adhering Male External Catheter | 2026-10-21 | Not applicable | C. R. Bard |
| Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With a Complicated Regimen (ARTISTRY-1) Bictegravir, Lenacapavir, BIC/LEN FDC | 2026-10-21 | Phase 2 / Phase 3 | Gilead Sciences |
| Cortical Network Modulation by Subthalamic Nucleus DBS Deep Brain Stimulation | 2026-10-21 | Not applicable | Washington University School of Medicine |
| Video Images About Decisions for Ethical Outcomes in the Emergency Department (VIDEO-ED) video decision aid, control arm ACP information sheet | 2026-10-21 | Not applicable | Massachusetts General Hospital |
| Electronic SBI(RT) for MSM in Argentina electronic screening and brief intervention., Phase 2: Assessment Only | 2026-10-21 | Not applicable | Florida State University |
| Electronic Quitline Referral With Enhanced Academic Detailing for the Promotion of Smoking Cessation Enhanced Academic Detailing, Informational Intervention | 2026-10-21 | Not applicable | OHSU Knight Cancer Institute |
| A Study Investigating the Efficacy and Safety of Intravitreal Injections of ANX007 in Patients With Geographic Atrophy ANX007, Sham comparator | 2026-10-21 | Phase 2 | Annexon, Inc. |
| Efficacy of a Vented Liner and Socket System for Individuals With Trans-femoral Amputation Vented suspension system, Non-vented suspension system | 2026-10-21 | Not applicable | Jóna Valgerður Kristjánsdóttir |
| A Study of Romosozumab (EVENITY®) in Postmenopausal Women in India With Osteoporosis at a High Risk of Fracture. Romosozumab | 2026-10-21 | Phase 4 | Amgen |
| Home-based tDCS in Frontotemporal Dementia or Alzheimer's Disease Computerized Cognitive Training, Active tDCS (tDCS) on DLPFC | 2026-10-21 | Not applicable | Johns Hopkins University |
| Lenvatinib, Pembrolizumab, and Paclitaxel for Treatment of Recurrent Endometrial, Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Lenvatinib, Paclitaxel, Pembrolizumab | 2026-10-21 | Phase 2 | Floor Backes, MD |
| Brentuximab Vedotin Plus Lenalidomide and Rituximab for the Treatment of Relapsed/Refractory DLBCL Brentuximab vedotin, Rituximab, Lenalidomide | 2026-10-21 | Phase 3 | Seagen, a wholly owned subsidiary of Pfizer |
| Biofeedback Based Virtual Reality Intervention to Manage Postoperative Pain Technology Based Intervention Group 1, Technology Based Intervention Group 2 | 2026-10-20 | Not applicable | Vanessa Olbrecht |
| Atezolizumab, Guadecitabine, and CDX-1401 Vaccine in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Atezolizumab, DEC-205/NY-ESO-1 Fusion Protein CDX-1401, Guadecitabine | 2026-10-20 | Phase 1 / Phase 2 | National Cancer Institute (NCI) |
| Examining the Role of the Orexin System in Sleep and Stress in Persons With Opioid Use Disorder Suvorexant, Placebos | 2026-10-20 | Phase 2 | Johns Hopkins University |
| Neoadjuvant PD-1 Inhibitor Dostarlimab (TSR-042) vs. Combination of Tim-3 Inhibitor Cobolimab (TSR-022) and PD-1 Inhibitor Dostarlimab (TSR-042) in Melanoma Dostarlimab (TSR-042) (singly), Dostarlimab (TSR-042) and TSR-022 (combination) | 2026-10-20 | Phase 2 | Diwakar Davar |
| Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers Nivolumab, Ipilimumab | 2026-10-20 | Phase 2 | Dana-Farber Cancer Institute |
| ElderTree Via a Voice Activated Device for Managing Chronic Health Conditions (NHLBI) ET-Text (Laptop), ET-Voice (Smart System) | 2026-10-20 | Not applicable | University of Wisconsin, Madison |
| Ketamine and Kidney Injury in Cardiac Surgery Ketamine, Propofol | 2026-10-20 | Phase 4 | Mayo Clinic |
| The Kentucky Viral Hepatitis Treatment Study Sofosbuvir/velpatasvir (Epclusa®) | 2026-10-20 | Phase 4 | Jennifer Havens |
| Translating Scientific Evidence Into Practice Using Digital Medicine and Electronic Patient Reported Outcomes Digital Transformation Network (DTN) Program | 2026-10-20 | Not applicable | Icahn School of Medicine at Mount Sinai |
| SELUTION SLR™ 014 In-stent Restenosis SELUTION SLR 014 DEB, Standard of Care | 2026-10-20 | Not applicable | M.A. Med Alliance S.A. |
| Anti-VEGF Therapy for Acute Thyroid Eye Disease Sub-tenon injection of saline followed by a sub-tenon injection of aflibercept, Sub-tenon injection of hyaluronidase (HA) followed by a sub-tenon injection of aflibercept, Sub-tenon injection of hyaluronidase (HA) alone | 2026-10-20 | Phase 2 | Massachusetts Eye and Ear Infirmary |
| A Clinical Study of Enlicitide in Participants With Severe Renal Impairment (MK-0616-032) Enlicitide | 2026-10-20 | Phase 1 | Merck Sharp & Dohme LLC |
| Study Assessing QBS72S For Treating Brain Metastases QBS72S | 2026-10-20 | Phase 2 | Melanie Hayden Gephart |
| Effects of Osteopathic Manipulative Treatment on Neuromuscular Control of the Head-neck System Osteopathic manipulative treatment, No intervention | 2026-10-20 | Not applicable | Michigan State University |
| A Study To Evaluate Hypofractionated Proton Therapy Or IMRT For Recurrent, Oligometastatic Prostate Cancer Intensity-Modulated Radiation Therapy, Proton Beam Radiation Therapy, Quality-of-Life Assessment | 2026-10-20 | Phase 2 | Mayo Clinic |
| A Study to Evaluate a Computerized Stethoscope Called ©Voqx to Diagnose Heart Disease ©VoqX stethoscope | 2026-10-20 | Not applicable | Mayo Clinic |
| Impact of Metformin on Immuno-virologic Parameters in HIV Metformin | 2026-10-20 | Phase 2 / Phase 3 | University of Hawaii |
| Corona Mortis in Patients Undergoing TEP for Inguinal Hernia TEP | 2026-10-20 | Sofia Med Hospital | |
| Suicide Prevention Integration Into Task-shifted Mental Health Interventions KPZ Program (KPZ), Enhanced Usual Care (EUC) | 2026-10-20 | Not applicable | Yale University |
| Outcomes of Partial Pulpotomy Treatment in Cariously Exposed Teeth Biodentine (calcium silicate-based cement) (Septodont, Saint Maur de Fossés, France), Theracal PT (resin modified calcium silicate-based cement) (Bisco Inc., Schaumburg, IL, USA) | 2026-10-20 | Phase 4 | Firat University |
| Testing a Barbershop-based HIV Prevention Initiative Among Men General, status-neutral HIV education, HIV self-test kits, Information about where to receive HIV prevention services | 2026-10-20 | Not applicable | HIV Prevention Trials Network |
| Neurocognitive Factors in EdTech Intervention Response GraphoLearn reading intervention, Math control intervention | 2026-10-20 | Not applicable | University of Connecticut |
| Confirming the Efficacy/Mechanism of Family Therapy for Children With Low Weight ARFID Family-based Treatment for ARFID, Manualized Non-Specific Usual Care for ARFID | 2026-10-20 | Not applicable | Stanford University |
| A Study of Ustekinumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis (UC) Ustekinumab Dose Based on BSA and Body Weight, Matching Placebo | 2026-10-20 | Phase 3 | Janssen Research & Development, LLC |
| Dynamic Airway CT is Diagnostic for Tracheomalacia in Children Dynamic Airway CT scan (DA-CT) | 2026-10-20 | Not applicable | NYU Langone Health |
| Prepare for Your Diabetes Care Prepare for Your Diabetes Care, Usual Care | 2026-10-20 | Not applicable | Kaiser Permanente |
| Golimumab and Apalutamide for the Treatment of Castration-Resistant Prostate Cancer, TRAMP Study Apalutamide, Biopsy, Biospecimen Collection | 2026-10-19 | Phase 2 | University of Washington |
| Families Becoming Healthy Together FBT, FBT+Variety | 2026-10-19 | Not applicable | The University of Tennessee, Knoxville |
| Blood-Brain Barrier Disruption Using Transcranial MRI-Guided Focused Ultrasound Transcranial ExABlate | 2026-10-19 | Not applicable | InSightec |
| Feasibility and Acceptability of the Propeller Monitoring System in Children With Persistent Asthma Propeller EMD | 2026-10-19 | Connecticut Children's Medical Center | |
| The Breakfast Study Breakfast | 2026-10-19 | Not applicable | University of Michigan |
| Study With Afuresertib and Paclitaxel in Platinum Resistant Ovarian Paclitaxel, Afuresertib | 2026-10-19 | Phase 2 | Laekna Limited |
| A Communication Tool to Improve Communication in the ICU Best Case/Worst Case-ICU Communication Tool | 2026-10-19 | Not applicable | University of Wisconsin, Madison |
| A Study of Rusfertide in Adults With Polycythemia Vera (PV) Rusfertide, Placebo | 2026-10-19 | Phase 3 | Protagonist Therapeutics, Inc. |
| IBIS Megastudy- Pilot Risk assessment messaging, U=U messaging, Healthy Living messaging | 2026-10-19 | Not applicable | University of California, San Francisco |
| A First in Human (FIH) Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DR10624 DR10624 for injection, Placebo | 2026-10-19 | Phase 1 | Zhejiang Doer Biologics Co., Ltd. |
| PortionSize Study 3: Assessment in Free-living Conditions | 2026-10-19 | Pennington Biomedical Research Center | |
| Evaluation of Aqueous Humor DEL-1 and IL-17 Levels in Diabetic Cataract Patients Observational Study Procedure | 2026-10-19 | Uşak University | |
| Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery CX 4945 | 2026-10-19 | Phase 1 / Phase 2 | Pediatric Brain Tumor Consortium |
| Nivolumab and BMS986205 in Treating Patients With Stage II-IV Squamous Cell Cancer of the Head and Neck Nivolumab, IDO1 Inhibitor BMS-986205, Therapeutic Conventional Surgery | 2026-10-19 | Phase 2 | Thomas Jefferson University |
| Clinical Study to Investigate the Ability of a Stannous Fluoride Toothpaste to Protect From Dentine Hypersensitivity Sensodyne Rapid Relief, Colgate Cavity Protection | 2026-10-19 | Not applicable | HALEON |
| A Study to Investigate Natural Killer Cell Engager (SAR443579) With Different Agents in Participants With Hematological Malignancies SAR443579, venetoclax, azacitidine | 2026-10-19 | Phase 1 / Phase 2 | Sanofi |
| Treating Primary Progressive Aphasia (PPA) Using High-definition tDCS high-definition transcranial direct current stimulation, modified constraint-induced language therapy | 2026-10-19 | Phase 2 | University of Pennsylvania |
| EO4010 in Previously Treated Metastatic Colorectal Carcinoma EO4010 | 2026-10-19 | Phase 1 / Phase 2 | Enterome |
| Aromatase Inhibitors and Weight Loss in Severely Obese Men With Hypogonadism anastrozole (1 mg/day), Placebo | 2026-10-19 | Phase 4 | Baylor College of Medicine |
| Phase 2B Study Assessing Pain Relief After Replacement of the Knee ATX101, bupivacaine hydrochloride, saline placebo | 2026-10-19 | Phase 2 | Allay Therapeutics, Inc. |
| A Drug-Drug Interaction Study to Assess the Pharmacokinetics of DC-806 When Orally Administered Alone, When Coadministered With Itraconazole, and When Coadministered With Carbamazepine in Healthy Adult Participants DC-806, Itraconazole, Carbamazepine | 2026-10-19 | Phase 1 | DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company |
| A Drug-Drug Interaction Study Evaluating the Perpetrator Potential of DC-806 on Cocktails of CYP450 Enzyme and Transporter Substrates in Healthy Participants DC-806, Midazolam, Repaglinide | 2026-10-19 | Phase 1 | DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company |
Trials whose overall status changed between 2026-10-16 to 2026-10-22 (started recruiting, completed, suspended, terminated, withdrawn...), with the reason when one was given.
| Trial | Change | Phase | Sponsor |
|---|---|---|---|
| Building Resilience and Appropriate Independence in Young Adults With Autism Life Skills and Resilience Program | Unknown → Completed | Not applicable | University of California, San Francisco |
| Effect of TECAR Therapy on Balance and Quality of Life in Elderly Men With Knee Osteoarthritis True TECAR Therapy, Sham TECAR, Traditional Physiotherapy | Not yet recruiting → Completed | Not applicable | Middle East University |
| Study to Investigate the Efficacy and Safety of Regimens Containing BRII-179, BRII-835, and PEG-IFNα Treating Chronic Hepatitis B Virus (HBV) Infection (ENRICH) BRII-179, BRII-835 (VIR-2218), PEG-IFNα | Active not recruiting → Completed | Phase 2 | Brii Biosciences Limited |
| Quality of Life in Children After Multisystem Inflammatory Syndrome in Children | Enrolling by invitation → Completed | Kristina Lah Tomulić | |
| Garlic Product Impact on Periodontitis (GPIP) Aged Garlic Extract | Unknown → Completed | Not applicable | Hadassah Medical Organization |
| "Machine Learning Analysis of Lingual Colorimetry and MADRS Anxiety-Depression Score in Acupuncture Patients" | Recruiting → Completed | Dr Benoit Bataille | |
| A Study to Test Experimental Blood Stage Malaria Vaccine in Burkina Faso. Rabies vaccine, RH5.1 10μg adjuvated with 50μg Matrix-M, RH5.2 5μg adjuvated with 50μg Matrix-M | Recruiting → Completed | Phase 1 / Phase 2 | University of Oxford |
| AMBULAPSE STUDY Feasibility Study on Laparoscopic Double-mesh Sacrocolpopexy With or Without Robotic Assistance, in Female Patients Presenting With Symptomatic Pelvic Organ Prolapse, Based on an Outpatient Treatment Model. outpatient laparoscopic | Recruiting → Completed | Not applicable | Centre Hospitalier Universitaire de Nice |
| Resistance Exercise With Blood Flow Restriction by Vascular Occlusion on Myocardial Function in Heart Failure With Reduced Ejection Fraction Application of a vascular restriction device during resistance training | Not yet recruiting → Recruiting | Not applicable | Centre Hospitalier Universitaire de Nīmes |
| Changes in Periodontal Pocket Depth After Periodontal Treatment Periodontal Treatment | Recruiting → Completed | Not applicable | Necmettin Erbakan University |
| Mechanisms of Anaphylaxis Biomarkers (platelet activating factor [PAF], anaphylatoxins) and basophil activation test (BAT) | Unknown → Active not recruiting | Haukeland University Hospital | |
| Exploratory Study on Bio-signal Telemonitoring Using Electronic Textiles in a Pediatric Acute and Critical Care Setting Skiin pediatric band and Skiin biometric pod | Unknown → Recruiting | The Hospital for Sick Children | |
| Peer Support in Alcohol Dependence Quality life questionnaire AQoLS, Quality life questionnaire Euroqol EQ-5D-5L, Peer support consultations | Not yet recruiting → Recruiting | Not applicable | Hospices Civils de Lyon |
| Evaluation of the Effectiveness of Patient Therapeutic Education on Chronic Insomnia therapeutic education, Actimetry | Recruiting → Completed | Not applicable | Centre Hospitalier Universitaire de Nīmes |
| Just-in-Time Coping Prompts for Reactive Digital Behavior in College Students Momentary coping prompt, Active control message | Not yet recruiting → Recruiting | Not applicable | University of Florida |
| Myofunctional Therapy for Children With OSA Myofunctional therapy | Not yet recruiting → Recruiting | Not applicable | Chinese University of Hong Kong |
| Laser Therapy for Dentin Hypersensitivity Er,Cr;YSGG Laser, Waterlase, Biolase Technology Inc., Irvine, CA, ABD, Remin Pro (VOCO, Cuxhaven, Germany) | Active not recruiting → Completed | Not applicable | Hacettepe University |
| A Study to Investigate the Effects of Zovaglutide (ZT002 Injection) on QTc Interval in Healthy Adults ZT002 injection, ZT002 injection matching placebo | Not yet recruiting → Active not recruiting | Phase 1 | Beijing QL Biopharmaceutical Co.,Ltd |
| BaLloon-based PFA Ablation poST Approval Outcomes for PAF and PersAF Pulsed Field Ablation | Recruiting → Active not recruiting | Not applicable | Abbott Medical Devices |
| Preterm Infants on Early Solid Foods Early intervention group, Late intervention group | Unknown → Completed | Not applicable | Medical University of Vienna |
| TRIFORMIS RESILIA Real-world Study Assessing Safety and Performance (TRIBLAZE Study) Edwards TRIFORMIS RESILIA heart valve | Not yet recruiting → Recruiting | Edwards Lifesciences | |
| Respiratory Virus Metagenomics After COVID-19 | Recruiting → Active not recruiting | Chinese University of Hong Kong | |
| SPSIP Block in Shoulder Artroscopy SPSIPB block | Not yet recruiting → Recruiting | ULSS6 - Ospedale di Piove di Sacco | |
| Development of a Precision Nutrition Expert System Combining AI Dietary Image Recognition and Big Data Analysis: A Case Study on Kidney Disease CKDcare | Active not recruiting → Completed | Not applicable | China Medical University Hospital |
| Point-of-Care Troponin Testing in the Emergency Department Point-of-Care high-sensitivity troponin testing | Recruiting → Active not recruiting | Not applicable | KU Leuven |
| Glucose Disturbances in Premature Infants and Quality of Life | Unknown → Completed | Clinical Hospital Center Rijeka | |
| Evaluation of Balance Using the Biodex Balance System Among Different Subcategories of Low Back Pain Assessment of balance will be measured by The Biodex Balance System (BBS) which computes Postural Stability key indices: the medial-lateral stability index (MLSI), anterior-posterior stability index | Not yet recruiting → Completed | Not applicable | Cairo University |
| Aging Stereotypes and Prodromal Alzheimer's Disease Diagnosis of MCI versus No MCI (SCI or healthy patient) | Unknown → Completed | Not applicable | Assistance Publique Hopitaux De Marseille |
| Adolescents and Young Adults With Cancer: Their Preferred Involvement in Decision Making Clinical Decision-Making Scenarios and Preferences Assessment | Recruiting → Completed | Not applicable | Stanford University |
| The Effect of Blood Carboxyhemoglobin Levels on NF-kB, NRF2 and PGC-1α During Low-flow and Normal-flow Anesthesia low-flow anasthesia, Normal akımlı anestezi | Recruiting → Completed | Not applicable | Ataturk Training and Research Hospital |
| Platform Study of JDQ443 in Combinations in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation JDQ443, trametinib, Ribociclib | Active not recruiting → Terminated Business reasons and not based on any safety concerns. | Phase 1 / Phase 2 | Novartis Pharmaceuticals |
| Study of PN20 in Adult Patients With Primary Immune Thrombocytopenia (ITP) PN20 treatment | Recruiting → Completed | Phase 1 | Chongqing Peg-Bio Biopharm Co., Ltd. |
| Correlation and Clinical Utility of Urinary Biomarker in Membranous Glomerulonephritis urinary markers | Unknown → Recruiting | Chinese University of Hong Kong | |
| Aortic Dissection Detection Risk Score With D-dimer to Rule-Out Acute Aortic Syndrome D-dimer test | Not yet recruiting → Recruiting | Chinese University of Hong Kong | |
| Effects of Reflexology and Cold Application Before Chest Tube Removal in CABG Patients Reflexology, Cryotherapy alone | Recruiting → Completed | Not applicable | Ankara University |
| REDUCTION ACCURACY IN NASO-ORBITO-ETHMOIDAL FRACTURES AFTER VIRTUAL REDUCTION AND FIXATION USING PRE-ADAPTED MINIPLATES pre-adapted titanium miniplates based on a virtually reduced 3D model | Recruiting → Completed | Phase 4 | Alexandria University |
| Investigating The Potential Of A Hay-Aged Cheese To Reduce Cholesterol As Mediated By Changes In The Gut Microbiome Hay-aged cheese, Cheddar control | Recruiting → Active not recruiting | Not applicable | Anisha Wijeyesekera |
| A Prospective Study of Cardiovascular Risk of Patients Admitted for Acute Exacerbation of COPD Intervention Group, Usual Care | Not yet recruiting → Recruiting | Not applicable | Chinese University of Hong Kong |
| EFFECT OF MULLIGAN CERVICAL SUSTAINED NATURAL APOPHYSEAL GLIDE ON POSTURAL STABILITY IN PATIENTS WITH CHRONIC NECK PAIN 1- The Biodex Balance System (BBS), 2-The Numerical Pain Rating Scale (NPRS), 3- The Neck Disability Index (Arabic version) for functional disability | Not yet recruiting → Recruiting | Not applicable | Menna Allah Ahmed Marei Elnaggar |
| Pharmacokinetic, Safety and Immunogenicity Study of New Process CMAB015 and Cosentyx in Healthy Volunteers Secukinumab 150mg s.c. | Active not recruiting → Completed | Phase 1 | Taizhou Mabtech Pharmaceutical Co.,Ltd |
| EFFICACY OF ARTIFICIAL INTELLIGENCE DRIVEN PROGRAM VERSUS TRADITIONAL PHYSICAL THERAPY PROGRAM IN PATIENTS WITH LOW BACK DYSFUNCTION AI-Driven Rehabilitation Program, Traditional Physical Therapy Program | Not yet recruiting → Recruiting | Not applicable | Cairo University |
| Smoking Relapse Prevention in Patients With Cancer Standardized Brief Relapse-Prevention Counseling, Add-on One-Session Structured CBT-Based Relapse-Prevention Counseling | Not yet recruiting → Recruiting | Not applicable | Vietnam National Cancer Hospital |
| Contribution of a Virtual Reality Program in the Treatment of Dysmorphophobia for Adolescent Female With Anorexia Nervosa self-evaluation of the Body Mass Index, Cognitive-behavioral psychotherapies | Unknown → Completed | Not applicable | Assistance Publique Hopitaux De Marseille |
| Clinical Cohorts for Validation of New Digital Biomarkers | Unknown → Completed | Atrial Fibrillation Network | |
| Down Sizing Strategy (HANGZHOU Solution) vs Standard Sizing Strategy TAVR in Bicuspid Aortic Stenosis (Type 0) TAVR for BAV Using Down Sizing with the Evolut Pro platform, TAVR for BAV Using Traditional Sizing strategy with the Evolut Pro platform | Recruiting → Active not recruiting | Not applicable | Second Affiliated Hospital, Zhejiang University, School of Medicine |
| A Phase I/II, First-in-Human Study to Evaluate TJ102 in Participants With Advanced or Metastatic Ovarian Cancer and Other Solid Tumors. TJ102 | Not yet recruiting → Recruiting | Phase 1 / Phase 2 | Phrontline Biopharma |
| Effectiveness of Positive Deviance/Hearth in Treating Uncomplicated Moderate Acute Malnutrition in Children 6-59 Months in Mymensingh Division, Bangladesh PD/Hearth is a behavioral change program that teaches caregivers how to cook and feed their children. A nutrient-dense meal using local ingredients will be fed to children during Hearth sessions., Standard of Care (Investigator Selected) | Not yet recruiting → Enrolling by invitation | Not applicable | World Vision US |
| Biomarkers in Apical Periodontitis laser activation, PUI, CSI | Not yet recruiting → Completed | Not applicable | Kırıkkale University |
| Aleniglipron Phase 2 in Type 2 Diabetes Mellitus Aleniglipron, Placebo | Active not recruiting → Completed | Phase 2 | Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics |
| Robotic Systems Evaluation for Peripheral Pulmonary Lesions (RISE Trial) RAB via the Monarch platform, RAB via the ION platform | Not yet recruiting → Recruiting | Not applicable | Case Comprehensive Cancer Center |
| Personalized Analgesia Through Central Nervous System Engagement to Unlock Performance Duloxetine, Placebo | Not yet recruiting → Recruiting | Phase 4 | Benedict Alter |
| Recovery, Analgesia And Delirium Profiles At Laparoscopic Abdominal and Gynecologic Surgeries With Processed EEG Monitoring Bispectral index monitoring | Not yet recruiting → Completed | Not applicable | Cukurova University |
| Virtual hIStology of Crohn's Disease Ex-vivo Resected Anatomical Lesions | Not yet recruiting → Recruiting | Central Hospital, Nancy, France | |
| The Combined Effect of N-Acetyl Cysteine and Metformin in Polycystic Ovary Syndrome Patients N-acetyl cysteine, Metfomin | Recruiting → Completed | Phase 3 | Cairo University |
| A Study to Investigate Efficacy and Safety of SAR441566 in Patients With Ulcerative Colitis SAR441566, SAR441566 matching Placebo | Active not recruiting → Terminated Business decision | Phase 2 | Sanofi |
| Preeclampsia Research on Vitamin D, Inflammation, & Depression mental health screening, education and referral program | Unknown → Active not recruiting | Not applicable | Cedars-Sinai Medical Center |
| Quantification of Motor Compensation Following Biomechanical, Proprioceptive and Physiological Alterations Post-lower Limb Amputation. Biomechanics, Physiological, Proprioceptive | Recruiting → Completed | Centre Hospitalier Universitaire de Nīmes | |
| Grafting of the Peri-implant Bony Defects Around Immediate Implants Using Xenogenic Versus Alloplastic Sticky Grafts Immediate dental implant with filling the peri implant gap with xenogenic sticky bone | Recruiting → Completed | Not applicable | Cairo University |
| Improve Muscle Weakness in Patient With COPD Aerobic Exercise Combined with Blood Flow Restriction, Aerobic exercise | Not yet recruiting → Withdrawn no participant enrolled | Not applicable | Al-Zaytoonah University of Jordan |
| Fetal Treatment of Galenic Malformations Fetal embolization of vein of Galen malformation using Target XL and XXL Detachable Coils | Active not recruiting → Completed | Not applicable | Darren Orbach |
| The Food Network Effect Food Related Visual Stimuli Exposure | Not yet recruiting → Recruiting | Not applicable | Casey Morehouse, DO |
| Circadian Rhythm and Cardiovascular Recovery After Submaximal Exercise | Not yet recruiting → Recruiting | Saglik Bilimleri Universitesi | |
| Prevalence of Sleep Apnoea in Adolescents | Unknown → Completed | Chinese University of Hong Kong | |
| HD Patients' Depression and Happiness | Unknown → Completed | Chang Gung University of Science and Technology | |
| Normal Saline Versus Heparin Intermittent Flushing for the Prevention of Occlusion in Port-a-Cath Normal Saline Flush 20 ml, Normal Saline Flush 10 ml, Heparin Flush (1000 USP, 10ml) | Unknown → Completed | Not applicable | Chang Gung Memorial Hospital |
| The Vitamin D in Pediatric Crohn's Disease ( ViDiPeC-2 ) vitamin D3 | Unknown → Terminated Enrollment stopped at 55 of 316 planned participants due to recruitment challenges related to the COVID-19 pandemic and funding constraints. All enrolled participants completed 52-week follow-up. | Phase 3 | Jantchou Prevost |
| The Effect of Education on Quality of Life, Adherence to Immunosuppressive Therapy and Symptom Control in Organ Transplant Patients Mobile application installation, Providing teaching booklets, Control | Not yet recruiting → Recruiting | Not applicable | Ondokuz Mayıs University |
| PICNIC Study - PatIent Centered aNtIbiotic Courses in Children With Medical Complexity Clinical Stability Assessment | Recruiting → Completed | Not applicable | Boston Children's Hospital |
| Ultrasound Guided Combined Adductor Canal, Superior Genicular Nerves and Anterior Femoral Cutaneous Nerves Blocks in Comparison With Periarticular Local Anesthesia Infiltration in Primary Total Knee Arthroplasty Periarticular Infiltration, Ultrasound-Guided Triple Block Technique | Completed → Not yet recruiting | Not applicable | SAMEH ELSHERBINI |
| Efficacy and Safety of Vamifeport in Adult Participants With Homeostatic Iron Regulator Gene (HFE)-Related Hereditary Hemochromatosis Vamifeport, Placebo | Recruiting → Active not recruiting | Phase 2 | CSL Behring |
| Effects of MK-3475 (Pembrolizumab) on the Breast Tumor Microenvironment in Triple Negative Breast Cancer Merck 3475 Pembrolizumab, Intraoperative radiation therapy (IORT) | Unknown → Completed | Phase 1 | Columbia University |
| Continuous Glucose Monitoring in Patients With Diabetes on Peritoneal Dialysis | Unknown → Recruiting | Coordinación de Investigación en Salud, Mexico | |
| Safe and Timely Antithrombotic Removal (STAR) Registry CytoSorb | Recruiting → Active not recruiting | CytoSorbents, Inc | |
| Effects of Ketones on Brain Energetics and Alcohol Consumption in Alcohol Use Disorder Kenetik, magnetic resonance imaging scan, Alcohol bar lab | Not yet recruiting → Recruiting | Phase 2 / Phase 3 | University of Pennsylvania |
| Online-Delivered Core Stability Exercises in Postpartum Women online core stability exercise group, an education-only control group | Not yet recruiting → Enrolling by invitation | Not applicable | Prince Sattam Bin Abdulaziz University |
| Barriers Limiting OCT Penetration in Clinical Practice | Recruiting → Completed | Consorzio Futuro in Ricerca | |
| Frailty and Ultrasound-Guided Central Venous Catheterization Difficulty in Adult Cardiac Surgery Patients Ultrasound-Guided Internal Jugular Vein Catheterization | Not yet recruiting → Recruiting | Ankara City Hospital Bilkent | |
| Optical Coherence Tomography Guided Laser Treatment of Basal Cell Carcinoma 1064 nm long-pulse Nd:YAG laser | Active not recruiting → Completed | Not applicable | Christopher Zachary |
| A Study to Learn How Different Preparations of Osivelotor Taste and Enter the Blood With Food or Liquids or With an Antacid in Healthy Adults Osivelotor, Famotidine | Not yet recruiting → Recruiting | Phase 1 | Pfizer |
| Breathwork and Stress: Investigating the Mechanisms of Action and Effectiveness of Breathing Interventions in Modulating the Psychophysiological Response to Acute Stress Test Coherent Breathing (6 bpm), Sham Breathing (15 bpm) | Active not recruiting → Completed | Not applicable | Medical University of Bialystok |
| Ischemic Post-conditioning in Acute Ischemic Stroke Thrombectomy (PROTECT-2) Mechanical thrombectomy combined with ischemic post-conditioning, Mechanical thrombectomy alone | Recruiting → Completed | Phase 2 | Capital Medical University |
| Bisacodyl Oral for Lowering Dysfunction (of Tenckhoff Catheter) Bisacodyl 5 mg | Not yet recruiting → Recruiting | Phase 4 | Chinese University of Hong Kong |
| Ventilator Trigger Sensitivity Adjustment Versus Threshold Inspiratory Muscle Training on Arterial Blood Gases Threshold inspiratory muscle trainer or ventilator pressure setting inspiratory muscle training techniques | Recruiting → Completed | Not applicable | Cairo University |
| The Effect of Mobile Application-Based Education Developed According to Orem's Self-Care Model in Multiple Myeloma Patients Mobile App Education | Active not recruiting → Completed | Not applicable | Ozlem |
| Neuropsychological Care for Maintaining Quality of Life After Radiation Therapy in Patients With Brain Metastases Best Practice, Neuropsychological Assessment, Quality-of-Life Assessment | Active not recruiting → Completed | Phase 2 | Ohio State University Comprehensive Cancer Center |
| Efficacy and Safety of Budesonide MMX® vs. Budesonide CR for Induction of Remission in Microscopic Colitis Budesonide MMX®, Budesonide controlled ileal release (CR) capsules | Not yet recruiting → Active not recruiting | Phase 2 | University of Calgary |
| Autoantibodies on Spinal Cord Injury Blood collection | Unknown → Completed | Hospital Nacional de Parapléjicos de Toledo | |
| Effect of Tiotropium on Airway Remodeling in Patients With Early Stage COPD Accessed by Optical Coherence Tomography Tiotropium Inhalation Powder [Spiriva] 0.018mg, Salbutamol sulphate aerosol (Ventolin) 0.1mg | Unknown → Completed | Not applicable | Guangzhou Institute of Respiratory Disease |
| Improving Outcome of Selected Patients With Non-resectable Hepatic Metastases From Colo-rectal Cancer With Liver Transplantation Liver transplant, Chemotherapy | Unknown → Completed | Phase 2 | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano |
| Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors PF-07220060, Letrozole, Fulvestrant | Active not recruiting → Recruiting | Phase 1 / Phase 2 | Pfizer |
| Thailand Birth and Infant Outcomes Study | Not yet recruiting → Active not recruiting | Mead Johnson Nutrition | |
| Motor Performance Improvement After Visual Rehabilitation Virtual Reality rehabilitation | Recruiting → Completed | Not applicable | Instituto de Investigación Sanitaria Aragón |
| Investigation of the Effects of Tele-Yoga Training in Individuals With Lung Cancer Undergoing Lung Resection Surgery Tele-Yoga Training | Recruiting → Completed | Not applicable | Istanbul University |
| Psoas Tenotomy Under Ultrasound Psoas tenotomy under ultrasound | Recruiting → Terminated Failure of the surgical procedure under investigation to achieve satisfactory results. | Not applicable | Centre Hospitalier Universitaire de Nice |
| SINUS WASH Pilot Study in Adults Testing Positive for COVID-19 Povidone-Iodine, Normal saline | Unknown → Completed | Phase 1 | Hampshire Hospitals NHS Foundation Trust |
| Positional Therapy for Childhood Obstructive Sleep Apnoea Positional device, Rematee Bumper Belt or Night Shift | Recruiting → Completed | Not applicable | Chinese University of Hong Kong |
| A Study to Assess the Experimental Malaria Vaccines R78C and RH5.1 Combined With R21/Matrix-M (a "Multi-stage" Malaria Vaccine) R21, RH5.1, R78C | Recruiting → Active not recruiting | Phase 1 | University of Oxford |
| A Phase 1 Study to Assess an Escalating Dose, Multi-prime Vaccination Schedule of R21/Matrix-M™ R21/Matrix M™ (Group 1), R21/Matrix M™ (Group 2), R21/Matrix M™ (Group 3) | Active not recruiting → Completed | Phase 1 | University of Oxford |
| Expanded Studies on the SCAPIS Stockholm Reexamination Cohort Coronary computer tomography (CCTA), Echocardiograhy and aortic ultrasound, Liver elastography | Recruiting → Active not recruiting | Danderyd Hospital | |
| MENA Regional Endovascular Intervention for Venous Cerebral Venous Sinus Thrombosis Endovascular Thrombectomy, Anticoagulation Therapy | Not yet recruiting → Recruiting | Not applicable | Middle East North Africa Stroke and Interventional Neurotherapies Organization |
| ACT-GLOBAL IA Thrombolysis(ACT-REACT-004)Domain Within the ACT-GLOBAL Adaptive Platform Trial-NCT06352632 Tenecteplase or Alteplase- depending upon availability at each treating centre, Control | Not yet recruiting → Recruiting | Phase 3 | University of Calgary |
| Accuracy Testing of Validated and Non-validated Home BP Devices Sold on the Online Market. awake ABPM | Recruiting → Completed | Not applicable | Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal |
| Handheld US Device to Verify Vascular Cannulation Sonosite, Lumify® | Enrolling by invitation → Active not recruiting | Not applicable | Alok Moharir |
| RESOLUTE ONYX China RCT Study Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System, Resolute Integrity™ Zotarolimus-Eluting Coronary Stent System | Active not recruiting → Completed | Not applicable | Medtronic Vascular |
| Exploring the Effects of Transcutaneous Electrical Acupoint Stimulation Therapy on Patients After Video-Assisted Thoracoscopic Surgery Standard Analgesia, Transcutaneous Electrical Nerve Stimulation (TENS), Transcutaneous Electrical Acupoint Stimulation (TEAS) | Enrolling by invitation → Completed | Not applicable | Buddhist Tzu Chi General Hospital |
| IV-X Medical Peripheral Intravascular Lithotripsy Study for PAD IV-X Medical IVL System | Withheld → Not yet recruiting | Not applicable | IVX Medical |
| To Evaluate Whether IVUS-guided Drug-eluting Stent (DES) Implantation Leads to Better Clinical Outcomes Compared to Conventional Angiography in the Treatment of Chronic Complete Occlusion (CTO) Disease. The guidewire successfully passed the CTO lesion | Recruiting → Active not recruiting | Not applicable | CCRF Inc., Beijing, China |
| Pembrolizumab + MRGOO3 as Neoadjuvant in NPC Pembrolizumab & MRG003 | Not yet recruiting → Active not recruiting | Phase 2 | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology |
| Post-operative Medium Chain Triglyceride Diet May Reduce Hospital Stay Following Lung Resection MCT Diet | Recruiting → Not yet recruiting | Not applicable | Chinese University of Hong Kong |
| Prevention of COVID-19 Infection to Severe Pneumonia or ARDS EC-18, Placebo | Withdrawn → Not yet recruiting | Phase 2 | Enzychem Lifesciences Corporation |
| Site of Tracheal Extubation and Operating Room Efficiency During Robot-assisted Surgery Extubation in post-anesthesia care unit (PACU), Extubation in operating room (OR) | Recruiting → Completed | Not applicable | Peking University First Hospital |
| A Study of SHR-2906 Injection in Healthy Subjects With a Single Dose and in Obese Patients With Multiple Doses SHR-2906 Injection, SHR-2906 Injection Placebo | Recruiting → Active not recruiting | Phase 1 | Beijing Suncadia Pharmaceuticals Co., Ltd |
| A Clinical Trial Comparing the Efficacy and Safety of Different Doses of BL0175 Injection in Treating Postmenopausal Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Locally Advanced or Metastatic Breast Cancer BL0175 Injection | Not yet recruiting → Recruiting | Phase 2 | Shanghai Best-Link Bioscience, LLC |
| Research on Key Interventional Technologies for Controlling the Epidemic in High-prevalence Areas of Tuberculosis in Guangxi, China Active case finding | Recruiting → Completed | Not applicable | University of Toronto |
| A Study of MK-1484 as Monotherapy and in Combination With Pembrolizumab (MK-3475) In Advanced or Metastatic Solid Tumors (MK-1484-001) MK-1484, Pembrolizumab | Active not recruiting → Terminated Business Reasons | Phase 1 | Merck Sharp & Dohme LLC |
| Effectiveness and Cost-Effectiveness of a Digital Care Pathway and Asynchronous Communication for Patients With Hypertension Digital care pathway for hypertension, Asynchronous communication with nurse | Not yet recruiting → Recruiting | Not applicable | Wellbeing Services County of Pirkanmaa |
| A Study to Compare Pharmacokinetics, Efficacy and Safety of Subcutaneous CT-P44 and Darzalex Faspro in Combination With Lenalidomide and Dexamethasone in Patients With Refractory or Relapsed Multiple Myeloma CT-P44(Daratumumab), Darzalex Faspro(Daratumumab) | Recruiting → Active not recruiting | Phase 3 | Celltrion |
| Factor In the Initial Resuscitation of Severe Trauma 2 Patients Fibrinogen + PCC, Frozen Plasma | Unknown → Terminated Upon IDSMC's review of interim data, they recommended the trial be stopped based on futility. | Phase 4 | University Health Network, Toronto |
| Randomized Evaluation of Patients Who Have Had Laparoscopic Partial Nephrectomy Hemostatic Agent, No Hemostatic Agent | Active not recruiting → Completed | Not applicable | University of Chicago |
| Effectiveness of Ultrasound-guided Scalp Block for Supratentorial Craniotomy Ultrasound-guided scalp block with ropivacaine 0.375% | Unknown → Completed | Not applicable | University Malaysia Sarawak |
| Atopy Network - Comprehensive Allergy Centers: Medical Care of Patients With Moderate to Severe Allergic Diseases not applicable, observational study | Unknown → Recruiting | Charite University, Berlin, Germany | |
| Quit2Heal Smartphone App in Helping Cancer Patients Quit Smoking Quit2Heal, QuitGuide, Survey Administration | Active not recruiting → Completed | Not applicable | Fred Hutchinson Cancer Center |
| Intelligent Sports Injury Prevention and Training System Lower extremity and core muscle training | Unknown → Recruiting | Not applicable | National Taiwan University Hospital |
| Microbiome and Metabolomics Profiling in Children With OSA | Unknown → Recruiting | Chinese University of Hong Kong | |
| Efficacy and Safety of Methylene Blue in the Treatment of Severe Septic Shock Methylene Blue Intervention Group, Normal Saline Control Group | Unknown → Recruiting | Not applicable | First Affiliated Hospital of Zhejiang University |
| Backward Walking and Related Factors in Individuals With Stroke Assesment | Not yet recruiting → Completed | Gaziantep Islam Science and Technology University | |
| Early Temporal Dynamics of Optic Nerve Sheath Diameter After Therapy in GCA Optic Nerve Sheath Ultrasound, Temporal artery ultrasound, Bloodwork : CRP and ESR | Not yet recruiting → Recruiting | Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal | |
| Bed Bridge Test in Acute Stroke Patients Assesment test for Validity and Reliability | Not yet recruiting → Completed | Gaziantep Islam Science and Technology University | |
| Comparison of Exergaming Training With Visual Feedback Training on Upper Limb Functions in Post Stroke Patients Exergaming Training, Visual Feedback Training | Unknown → Completed | Not applicable | Riphah International University |
| A Real-world Study of the Effectiveness of Angiotensin Receptor-Neprilysin Inhibitor Therapy in Hypertensive Patients in the United Arab Emirates | Not yet recruiting → Recruiting | Novartis Pharmaceuticals | |
| Hyperangulated vs Macintosh Blades for Intubation With Videolaryngoscopy in ICU Hyperangulated blade videolaryngoscope, Macintosh blade videolaryngoscope | Recruiting → Completed | Not applicable | Hospital Clinico Universitario de Santiago |
| Comparison of Two Methods of Immunoprophylaxis Against RSV in Term Newborns to compare vaccine and monoclonal antibody | Active not recruiting → Completed | Jean-Michel HASCOET | |
| Shade Matching and Patient Satisfaction of Yttria Stabilized Multilayered Zirconia and Lithium Disilicate Restorations Yttria stabilized multilayered (YML) zirconia restorations, Lithium disilicate restorations | Unknown → Completed | Not applicable | Cairo University |
| Peripheral Nerve Stimulation Therapy for Atrial Fibrillation Wrist Device, Ear Device, Sham Device | Unknown → Terminated The Sponsor and Principal Investigator have mutually agreed to initiate study closure due to prolonged recruitment challenges that have prevented the trial from meeting its enrollment milestones within the projected study timeline. | Not applicable | Cala Health, Inc. |
| Efficacy of Diacylglycerol Oil on Metabolic Risk Factors in Prediabetes Diacylglycerol oil, Colza Oil | Not yet recruiting → Recruiting | Not applicable | The First Affiliated Hospital of Guangdong Pharmaceutical University |
| Evaluation of the Use of a Biodegradable Endoprothesis in the Prevention of Post-Endoscopic Retrograde CholoangioPancreatography Pancreatitis Placement of ARCHIMEDES fast biodegradable stent during the Endoscopic Retrograde CholoangioPancreatography | Recruiting → Completed | Not applicable | Institut Paoli-Calmettes |
| Comparison of Two Different Dual-Task Training Methods in Patients With Parkinson's Disease Single Task Exercise Training, Motor-Motor Dual Task Exercise Training, Cognitive-Motor Dual Task Exercise Training | Recruiting → Completed | Not applicable | Saglik Bilimleri Universitesi |
| Robotic RVO Trial: Robot-assisted Retinal Vein Cannulation in Patients With Retinal Vein Occlusions Surgery with Preceyes Robot plus NHS standard of care | Active not recruiting → Recruiting | Not applicable | University of Oxford |
| A Phase 1, Open-Label, Dose-Escalation Study to Evaluate Safety, Tolerability, and Clinical Activity of CBX-663 in Participants With Relapsed or Refractory Myeloid Malignancies, Advanced Solid Tumors, or Recurrent or Progressive Glioblastoma. CBX-663 | Not yet recruiting → Recruiting | Phase 1 | Crossbow Therapeutics, Inc. |
| Treatment of Olecranon Fractures in the Elderly Tension band wiring or plate fixation, Active non-operative treatment with optional plaster cast | Recruiting → Active not recruiting | Not applicable | Oslo University Hospital |
| 68Ga-NYM207 PET/CT Imaging in Hepatocellular Carcinoma 68Ga-NYM207 PET/CT | Not yet recruiting → Recruiting | Phase 1 / Phase 2 | Peking Union Medical College Hospital |
| Study to Evaluate the Safety, Pharmacology and Efficacy of WIN378 in Adults With Moderate or Severe Asthma WIN378, Placebo | Active not recruiting → Recruiting | Phase 2 | Windward Bio |
| Real-time Symptom Monitoring Using ePROs to Prevent Adverse Events During Care Transitions ePRO Application | Recruiting → Terminated Grant Terminated by Sponsor | Phase 1 / Phase 2 | Brigham and Women's Hospital |
| A Study to Assess the Adverse Events and How Intravenously Infused Livmoniplimab in Combination With Budigalimab Moves Through the Bodies of Adult Chinese Participants With Locally Advanced or Metastatic Hepatocellular Carcinoma (HCC) Livmoniplimab, Budigalimab | Active not recruiting → Terminated Strategic considerations | Phase 1 | AbbVie |
| Electroacupuncture for Generalized Anxiety Disorder: Clinical Efficacy and Neuroimaging Mechanisms Electroacupuncture (EA), Sham Electroacupuncture (SEA), Medication | Not yet recruiting → Recruiting | Not applicable | Lishu Gao |
| Cervical Stiffness in Women With Threatened Preterm Labor Pregnolia System | Not yet recruiting → Recruiting | Pregnolia AG | |
| The FDR (Femoral Derotaton) Trail. Adolescent Lateral Entry Femoral Nail, Pediatric LCP Hip Plate System | Recruiting → Completed | Not applicable | Oslo University Hospital |
| Comparison of the Effect of Testosterone Administered for Micropenis Hypospadias Surgery With Bispectral Index Bispectral index (BIS) | Unknown → Completed | Namik Kemal University | |
| A Study of Single and Multiple Subcutaneous or Intravenous Doses of ADX-001 in Healthy Adults to Assess Safety, Effects, and Immune Response ADX-001, Placebo | Not yet recruiting → Recruiting | Phase 1 | Adaxion Therapeutics |
| Relationship Between Interoception and Postural Control in Constipation-Predominant Irritable Bowel Syndrome | Not yet recruiting → Recruiting | Saglik Bilimleri Universitesi | |
| Drug-drug Interaction Study of ZT002 Injection in Overweight and Obese Participants ZT002 injection, metformin, warfarin, ZT002 injection, rosuvastatin, digoxin | Recruiting → Active not recruiting | Phase 1 | Beijing QL Biopharmaceutical Co.,Ltd |
| Home Visitation Enhancing Linkages Project in Kansas e-SBI main session, e-SBI Booster Session, Text messaging | Not yet recruiting → Recruiting | Not applicable | The National Center on Addiction and Substance Abuse at Columbia University |
| Group-based Stabilization and Skill Training for Patients With Lasting Posttraumatic Reactions in Mental Health Care Group-based stabilization and skill training in addition to individual treatment, Treatment as usual | Recruiting → Active not recruiting | Not applicable | St. Olavs Hospital |
| A Study of Zovaglutide (ZT002 Injection) in Participants With Impaired Kidney Function and Healthy Participants Zovaglutide | Recruiting → Active not recruiting | Phase 1 | Beijing QL Biopharmaceutical Co.,Ltd |
| Autologous Serum Obtained by a Closed-Circuit Collection Device Autologous Serum 20% | Not yet recruiting → Active not recruiting | Phase 2 | GIANCARLO FATOBENE |
| NT-NOA - Novel Treatment of Some Men With Non-Obstructive Azoospermia Denosumab (Prolia), Letrozole (Aromatase Inhibitors) | Active not recruiting → Completed | Phase 1 / Phase 2 | Martin Blomberg Jensen |
| Dosimetry and Preliminary Clinical Application Study of a Novel Probe Targeting CD73 68Ga-dPNE, 18F-FDG | Recruiting → Completed | Early Phase 1 | First Affiliated Hospital of Fujian Medical University |
| Video Images About Decisions for Ethical Outcomes in the Emergency Department (VIDEO-ED) video decision aid, control arm ACP information sheet | Active not recruiting → Completed | Not applicable | Massachusetts General Hospital |
| China Treatment Trial for Tumor in Sellar Region With Unruptured Intracranial Aneurysm Tumor resection followed by aneurysm treatment, Aneurysm treatment followed by tumor resection, Observation | Not yet recruiting → Active not recruiting | Cheng sen | |
| A Study of SKB264 Versus Investigator's Choice Chemotherapy in Patients With Unresectable Recurrent or Metastatic Triple-Negative Breast Cancer SKB264, Paclitaxel, Nab-paclitaxel | Recruiting → Active not recruiting | Phase 3 | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. |
| The Role of Mandala Painting Before Surgery Mandala | Recruiting → Completed | Not applicable | Niran Çoban |
| AI Telemedicine Support for Primary Care Physicians in El Salvador DoctorSV AI Assistant, Standard Telemedicine Workflow (No AI) | Not yet recruiting → Completed | Not applicable | Hospital El Salvador |
| Effect of Video -Based vs Standard ınformation on Maternal Anxiety and Procedure Decision in Pregnant Woman Offered Amniocentesis or Cvs Multilingual Video-Based Patient Education, Standard Verbal Informed Consent | Not yet recruiting → Recruiting | Not applicable | Ankara City Hospital Bilkent |
| A Study of a Weight Loss Intervention in People With Endometrial Cancer Tirzepatide | Recruiting → Active not recruiting | Early Phase 1 | Memorial Sloan Kettering Cancer Center |
| Cold Stored Whole Blood in Cardiothoracic Surgery Whole Blood transfusion | Unknown → Withdrawn Withdrawn because of recruitment and protocol issues. | Not applicable | Haukeland University Hospital |
| Malaria Molecular Surveillance in Mozambique (Phase 2) LDH-based malaria rapid diagnostic test, Malaria rapid diagnostic test | Recruiting → Active not recruiting | Centro de Investigacao em Saude de Manhica | |
| A Clinical Study to Compare Functional Outcomes After Surgery Using a Transverse or Longitudinal Surgical Incision in the Skin. Longitudinal incision, Transverse incision | Unknown → Recruiting | Not applicable | Corporacion Parc Tauli |
| Assessment of the Ocular Microbiome in Health and Disease Eye swab | Recruiting → Completed | Vanderbilt University Medical Center | |
| NIRS and BIS Monitoring During Cerebral Aneurysm Coiling Near-Infrared Spectroscopy (NIRS) and Bispectral Index (BIS) Monitoring | Not yet recruiting → Recruiting | Dokuz Eylul University | |
| Efficacy and Safety of Digital Therapeutics for Improving Shoulder Function After Rotator Cuff Repair digital therapeutics, usual care | Recruiting → Active not recruiting | Not applicable | Samsung Medical Center |
| Child's Behavior Using Single Rotary File System Versus Manual Instrumentation in Pulpectomy of Primary Molars Fanta AF F one rotary files 20 taper 4, Manual files (k files ,Mani, Inc., Japan). | Not yet recruiting → Recruiting | Not applicable | Cairo University |
| Norepinephrine With Ephedrine Versus Norepinephrine Alone During Spinal Anesthesia for Cesarean Delivery Ephedrine and Norepinephrine infusion, Norepinephrine infusion | Not yet recruiting → Recruiting | Phase 4 | Cairo University |
| Telerehabilitation Exercise Program for Postoperative Recovery in Lung Cancer. Therapeutic Exercise-Based Telerehabilitation, Usual Postoperative Care | Not yet recruiting → Recruiting | Not applicable | University of Seville |
| PEMF Therapy in Shoulder Tendinopathy Nanopulsed Electromagnetic Field Therapy (SIS), Balneophysiotherapy | Recruiting → Completed | Not applicable | Balnear and Rehabilitation Sanatorium Techirghiol |
| POCUS Screening for TAA in Hypertensive Patients in the ED Point-of-care ultrasound | Not yet recruiting → Completed | Chinese University of Hong Kong | |
| Electronic SBI(RT) for MSM in Argentina electronic screening and brief intervention., Phase 2: Assessment Only | Terminated → Completed | Not applicable | Florida State University |
| A Novel Aromatase Inhibitor, Leflutrozole, for Treatment of Non-Obstructive Azoospermia Leflutrozole, Dose 2 | Recruiting → Active not recruiting | Phase 1 / Phase 2 | Martin Blomberg Jensen |
| Short-term Effects of Osteopathic Manipulations on Heart Rate Variability in Lung Cancer Patients - A Randomized Pilot Study Osteopathic treatment, Quality of life assessment, Anxiety assessment | Not yet recruiting → Recruiting | Not applicable | Centre Hospitalier Henri Duffaut - Avignon |
| High-Power Short-Duration Radiofrequency Ablation in Patients With Typical Atrial Flutter Conventional cavotricuspid isthmus ablation, High-power short-duration ablation | Unknown → Completed | Not applicable | Jose Luis Ibañez Criado |
| A Study Comparing the Effect and Safety of Linaprazan Glurate to Lansoprazole in Participants With Erosive Esophagitis (EE) Due to Gastroesophageal Reflux Disease (GERD) Linaprazan glurate 50 mg Twice Daily (BID), Linaprazan Glurate 50 mg Once Daily (QD), Lansoprazole 30 mg Once Daily (QD) | Active not recruiting → Completed | Phase 3 | Cinclus Pharma Holding AB |
| Clinical Evaluation of a Novel Trifocal IOL LPYWT0, PXYWT0, Cataract Surgery | Not yet recruiting → Recruiting | Not applicable | Alcon Research |
| Electronic Quitline Referral With Enhanced Academic Detailing for the Promotion of Smoking Cessation Enhanced Academic Detailing, Informational Intervention | Active not recruiting → Completed | Not applicable | OHSU Knight Cancer Institute |
| Boston Early-Onset Chronic Obstructive Pulmonary Disease (COPD) Study | Recruiting → Completed | Brigham and Women's Hospital | |
| PREMEDICAL is a Clinical Investigation Aiming to Create a Data Basis That Can be Used to Enrich Information Collected in the Course of the Classic Patient Journey. Patients in the Emergency Department Will be Asked to Answer Patient-related and Symptom-oriented Questions. Minimum Age is 18 Years | Recruiting → Terminated Funding issues, recruitment targets not met | XUND Solutions GmbH | |
| Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Sickle Cell Disease autologous bone marrow derived CD34+ HSPCs electroporated with BCL11A enhancer targeting Cas9 ribonucleoprotein, Sequencing Assay for Variant rs114518452 | Not yet recruiting → Recruiting | Phase 1 | Daniel Bauer |
| Pharmacist-Led Treat-to-Target Urate Lowering Therapy in Patients With Gout Pharmacist-Led | Not yet recruiting → Recruiting | Not applicable | VA Office of Research and Development |
| Efficacy and Safety of Myopic Macular Hole Closure Surgery Without Endotamponade Agent ILM flap with no endotamponade technique | Active not recruiting → Completed | Not applicable | Chinese University of Hong Kong |
| A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease VHB937, Placebo | Recruiting → Active not recruiting | Phase 2 | Novartis Pharmaceuticals |
| Pharmacokinetics of Apixaban in Peritoneal Dialysis Apixaban | Unknown → Completed | Chinese University of Hong Kong | |
| Efficacy of a Vented Liner and Socket System for Individuals With Trans-femoral Amputation Vented suspension system, Non-vented suspension system | Withheld → Completed | Not applicable | Jóna Valgerður Kristjánsdóttir |
| RESOLUTE ONYX China Single Arm Study Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System | Active not recruiting → Completed | Not applicable | Medtronic Vascular |
| MediPD: An Online Mediterranean Diet Program for People Living With Parkinson's Disease MediPD Online Mediterranean Diet Program | Not yet recruiting → Recruiting | Not applicable | Queen's University, Belfast |
| Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Volunteers | Active not recruiting → Completed | National Institute of Mental Health (NIMH) | |
| Acceptance and Commitment Therapy for Depressed People With Spinal Cord Injuries Acceptance and commitment therapy (ACT) | Active not recruiting → Completed | Not applicable | University of South Florida |
| Effects of Clinical Pilates on Pain and Quality of Life in Women With Dyspareunia Clinical Pilates Exercise | Not yet recruiting → Completed | Not applicable | Okan University |
| Scheduled or as Needed Pain Regimen? Motrin and narcotic | Recruiting → Active not recruiting | Phase 4 | Cape Fear Valley Health System |
| Trial for Surgical Treatment of Reducible Atlantoaxial Dislocation Intra-articular Cages | Unknown → Recruiting | Not applicable | Xuanwu Hospital, Beijing |
| Assessment of Physical Performance in Children | Active not recruiting → Completed | Afyonkarahisar Health Sciences University | |
| Effect Of Brain Gym Exercises On Balance And Quality Of Life In Children With Spastic Diplegia Brain gym exercises, Conventional physical therapy program | Recruiting → Completed | Not applicable | Cairo University |
| BHV-7000 Responsive Neurostimulation System (RNS) Study BHV-700 | Active not recruiting → Completed | Phase 1 | Yale University |
| An Open-label DDI Study to Investigate the Effect of Rilzabrutinib on P-gp, BCRP, OATP1B1 and OATP1B3 Inhibition Rilzabrutinib, Rosuvastatin, Digoxin | Recruiting → Active not recruiting | Phase 1 | Sanofi |
| Rise & Thrive: Community-Engagement Intervention for Stress and Depression in Youth. Rise Together: Community Engagement Intervention, Adulting 101: Life Skills | Not yet recruiting → Recruiting | Not applicable | Ann & Robert H Lurie Children's Hospital of Chicago |
| Helpline Pilot Factorial Trial Standard Helpline (SH), Motivational Interviewing (MI), Coping Skills Training (CST) | Not yet recruiting → Recruiting | Not applicable | The National Center on Addiction and Substance Abuse at Columbia University |
| Arterial Stiffness and Endothelial Function in Heart Failure Study Assessment | Not yet recruiting → Recruiting | Coventry University | |
| Factors Associated With Occluding the Upper Esophagus by Paratracheal Force | Unknown → Completed | SMG-SNU Boramae Medical Center | |
| Efficacy of PErioperative PEmbrolizumab Treatment in Patients With Resectable Metastases From Kidney Cancer Pembrolizumab injection plus metastasis directed treatment (surgery or RT), Tumor resection or RT | Unknown → Active not recruiting | Phase 2 | Consorzio Oncotech |
| Pulmonary Hypertension (PH) Biorepository for Translational Research | Not yet recruiting → Recruiting | National Institutes of Health Clinical Center (CC) | |
| The MOUD Plus Pilot: Counseling and Peer Support to Support Retention for Medically Complex Patients With Opioid Use Disorder Seen In Primary Care MOUD "Plus" Intervention (treatment as usual + coordinated counseling and referral to community based peer), Treatment As Usual (primary care with low threshold MOUD prescribing) | Recruiting → Active not recruiting | Not applicable | Oregon Health and Science University |
| Digital Lifestyle Intervention for Lung Cancer Survivors Lifestyle | Recruiting → Completed | Not applicable | Kai-Uwe Schmitt, PhD, MEng, ICID |
| Serum Neurofilament-light Chain and GFAP Levels in Patients From the OFSEP Cohort at Different Landmarks of Multiple Sclerosis Blood sample | Recruiting → Active not recruiting | Centre Hospitalier Universitaire de Nīmes | |
| A Study Comparing BL-B01D1 With Chemotherapy of Physician's Choice in Patients With Recurrent or Metastatic Urothelial Carcinoma(PANKU-Bladder01) BL-B01D1, Docetaxel or Paclitaxel | Recruiting → Active not recruiting | Phase 3 | Sichuan Baili Pharmaceutical Co., Ltd. |
| This Study Evaluates the Impact of the Sodium Management Tool (SMT) on Hemodialysis Patient Outcomes Compared to Standard Care dialysis assisted with the sodium management tool | Not yet recruiting → Completed | Not applicable | Luzerner Kantonsspital |
| Daunorubicin, Cytarabine, and Midostaurin in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia cytarabine, daunorubicin, midostaurin | Unknown → Completed | Phase 3 | Alliance for Clinical Trials in Oncology |
| A Phase III, Multicentre Study to Evaluate Consolidation Treatment With AZD0120 Compared With ASCT, in Participants With Newly Diagnosed Multiple Myeloma Who Are Transplant Eligible (DURGA-6). AZD0120, Cyclophosphamide, Fludarabine | Not yet recruiting → Recruiting | Phase 3 | AstraZeneca |
| The Patient and Family Centered I-PASS LISTEN Study: Language, Inclusion, Safety, and Teamwork for Equity Now PFC I-PASS Intervention, PFC I-PASS+ Intervention | Recruiting → Active not recruiting | Not applicable | Boston Children's Hospital |
| Comparison of the Breast Tumor Microenvironment Breast tissue collection, Blood sample collection | Active not recruiting → Completed | Columbia University | |
| CITE: Clinical Inference Tethered to Evidence - a Retrieve-and-verify Layer for AI Care Plans CITE evidence-grounding retrieve-and-verify layer, AI care plan with safety guardrails | Not yet recruiting → Completed | Not applicable | Waymark |
| Cervical Spinal Cord Signal Abnormalities in Patients With Cervical Radicular Pain Clinical and Cervical MRI Assessment | Not yet recruiting → Recruiting | Ankara City Hospital Bilkent | |
| Preoperative Sleep Quality and Postoperative Outcomes in Breast Surgery Preoperative Sleep Quality Assessment (PSQI) | Recruiting → Completed | Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital | |
| A Randomized, Double-Blind Controlled Comparison of NRX-101 vs. Placebo for Adults Being Treated With Robotic Transcranial Magnetic Stimulation for Treatment Resistant Depression: The SPARC-TMS Trial Neuronavigated robotic-enabled TMS, NRX-101, Sham TMS | Not yet recruiting → Recruiting | Phase 2 / Phase 3 | NeuroRx, Inc. |
| Bronchoscopic Airway Clearance for Improving Lung Aeration in Mechanically Ventilated Patients With Atelectasis Flexible Bronchoscopy-Guided Airway Clearance, Usual Airway Care | Not yet recruiting → Recruiting | Not applicable | Southeast University, China |
| The European Robotic Spinal Instrumentation (EUROSPIN) Study Transpedicular Instrumentation | Active not recruiting → Completed | Marc Schröder | |
| A Study to Evaluate the Long-term Safety and Efficacy of Lunsekimig in Adult Participants With Chronic Obstructive Pulmonary Disease (COPD) Lunsekimig | Recruiting → Enrolling by invitation | Phase 3 | Sanofi |
| China Glomerulonephritis Kidney Transplant Recipient Cohort: A Prospective Multicenter Observational Study | Not yet recruiting → Recruiting | AstraZeneca | |
| Navigation Interventions for Patients With Breast Cancer and High-risk Social Determinants of Health Patient navigator | Not yet recruiting → Recruiting | Not applicable | Washington University School of Medicine |
| Automating Tobacco Cessation in Primary Care Tobacco counseling resources | Not yet recruiting → Recruiting | Not applicable | University of Pennsylvania |
| Feasibility and Effects of Noninvasive Brain Stimulation on Pain Perception in People With Fibromyalgia Primary Motor Cortex Stimulation, Occipital Lobe Stimulation | Not yet recruiting → Recruiting | Not applicable | Pulkit Grover |
| Contribution of 7 Tesla MRI of the Hypothalamus in the Diagnosis of Type 1 Narcolepsy 7T MRI | Unknown → Completed | Not applicable | Assistance Publique Hopitaux De Marseille |
| Improving Maternal Nutrition in Matlab In-home, intensive nutrition counseling | Unknown → Completed | Not applicable | International Centre for Diarrhoeal Disease Research, Bangladesh |
| Dose Low Dose Ketamine in Casesarian Application of ketamine and midazolam or ketamine alone to patients undergoing cesarean section under spinal anesthesia | Unknown → Completed | Inonu University | |
| Impact of Preoperative Dental Screening in Reducing Infective Endocarditis Risk in Transcatheter Aortic Valve Implantation Patients No preoperative dental screening | Unknown → Recruiting | Odense University Hospital | |
| IV-X Medical First-in-Human Peripheral Intravascular Lithotripsy Study for PAD IV-X Medical IVL System | Not yet recruiting → Active not recruiting | Not applicable | IVX Medical |
| Turkish Validity and Reliability of the Behavioral Indicators of Pain Scale(ESCID) The ESCID scale | Recruiting → Completed | Not applicable | Saglik Bilimleri Universitesi |
| RCT of Combination Effect of Vibration Treatment and HMB Supplementation on Myosteatosis and NMJ Degeneration Low-magnitude High-frequency Vibration, β-hydroxy β-methylbutyrate (HMB) supplement, Protein supplement | Recruiting → Completed | Not applicable | Chinese University of Hong Kong |
| CareCOPD - COPD Home Monitoring Study CareCOPD Platform | Unknown → Active not recruiting | Cognita Labs LLC | |
| Oxygen Toxicity: Mechanisms in Humans Sleep Deprivation, Caffeine, Methylphenidate | Suspended → Recruiting | Not applicable | Duke University |
| Trial in Healthy Volunteers to Evaluate 150 mg Subcutaneous CIT-013 CIT-013 high dose, Placebo | Not yet recruiting → Completed | Phase 1 | Citryll BV |
| Optimizing the Follow-Up Journey in Interstitial Lung Disease: The OPTIMIZE-ILD-2 Trial Standard ILD Follow-Up Pathway, Optimized One-Day ILD Follow-Up Circuit | Recruiting → Active not recruiting | Not applicable | Hospital de Granollers |
| Refugee Mental Health and Wellness Pilot Study Wellbeing Program | Unknown → Withdrawn Investigator has left UCLA and the study is closed without enrollment | Not applicable | University of California, Los Angeles |
| SIM0718 Treatment of Asthma Clinical Study SIM0718 injection, SIM0718 injection of placebo | Recruiting → Active not recruiting | Phase 3 | Simcere Pharmaceutical Co., Ltd |
| Evaluation of Metformin Effect on the Fertility of Women Treated With 131I for Thyroid Cancer metformin, Radioactive iodine (I-131) | Unknown → Recruiting | Phase 3 | Medical University of Bialystok |
| Whole-Body Vibration in Patients With Patellofemoral Pain Syndrome Whole body vibration, Sham Whole Body Vibration | Not yet recruiting → Completed | Not applicable | Pamukkale University |
| Evaluation of the Effect of Adding Sodium Bicarbonate to Lidocaine in the Treatment of Myofascial Pain Syndrome Lidocaine 2 %, Lidocaine + Sodium Bicarbonate | Not yet recruiting → Recruiting | Not applicable | Cairo University |
| Antimicrobial Photodynamic Therapy With ICG-Loaded Nanoparticles for Periodontitis Management Non- surgical periodontal therapy followed by photodynamic therapy with ICG-loaded nanoparticles, Non- surgical periodontal therapy followed by photodynamic therapy with ICG-loaded macroparticles, Non- surgical periodontal therapy only | Recruiting → Completed | Phase 2 | Nada Mahmoud Soliman |
| A Pilot Study to Evidence Improved Cranial Flap Fixation With a Bioresorbable Bone Adhesive Tetranite for Cranial Flap Fixation (TN-CFF) | Active not recruiting → Completed | Not applicable | RevBio |
| Palmitoylethanolamide vs Ibuprofen for Pain After ESWL Palmitoylethanolamide (PEA), Ibuprofen (Brufen®) | Not yet recruiting → Completed | Not applicable | Benha University |
| Evaluation of the Efficacy and Safety of Befotertinib Combined With Bevacizumab as First-Line Treatment for EGFR-Positive Non-Small Cell Lung Cancer With Brain Metastases: A Single-Arm, Open-Label, Prospective Phase II Clinical Study The treatment regimen is Befotertinib combined with Bevacizumab. | Recruiting → Active not recruiting | Phase 2 | Li-kun Chen |
| Investigating Baby Behavior and Family Technology Use Study Technology Use during Feeding Conditions | Recruiting → Active not recruiting | Not applicable | California Polytechnic State University-San Luis Obispo |
| Clinical Study Evaluating the Anticancer Effect of Pentoxiphylline in Patients With Metastatic Colorectal Cancer Pentoxifylline, FOLFOX, XELOX | Unknown → Completed | Phase 4 | Tanta University |
| Healthy Lifetime - Phase 2 Nurse-led health coaching | Recruiting → Completed | Not applicable | University of Michigan |
| BEhavioral and Adherence Model for Improving Quality, Health Outcomes and Cost-Effectiveness of healthcaRe B-COMPASS implementation | Recruiting → Completed | Not applicable | Technical University of Madrid |
| Combined Effect of Biofeedback and Scapular Stabilization Exercises in Children With Swimmer's Shoulder Designed scapular stabilization using pressure biofeedback, Designed physical therapy program | Not yet recruiting → Completed | Not applicable | Cairo University |
| CAMELLIA Cohort: A Longitudinal Study to Understand Sexual Health and Prevention Among Women in Alabama Camelia Cohort | Enrolling by invitation → Active not recruiting | Not applicable | University of Alabama at Birmingham |
| CT-Based Scoring System to Predict Surgical Need in Tracheal Stenosis (TSMAS Study) CT-Based Morphologic and Attenuation Scoring | Not yet recruiting → Completed | Ondokuz Mayıs University | |
| Development and Evaluation of a Virtual Reality Tool for At-Risk Trauma-Exposed Young People Virtual Reality Tool | Recruiting → Active not recruiting | Not applicable | Medical University of South Carolina |
| Hemoglobin Levels for Blood Transfusions During and After Surgery Restrictive Transfusion, Liberal transfusion | Recruiting → Active not recruiting | Not applicable | Ottawa Hospital Research Institute |
| The Effects of Claudication Severity on Functional Outcomes Pain Free Exercise (PF), Moderate Claudication Pain Exercise (MOD-P), Maximal Claudication Pain Exercise (MAX-P) | Unknown → Completed | Not applicable | University of Central Lancashire |
| Chewing Gum and Cold Gargle on Post-Bronchoscopy Symptoms Chewing Gum, Cold Water Gargle | Recruiting → Completed | Not applicable | Ankara University |
| MIECC vs Conventional Cardiopulmonary Bypass and Systemic Inflammation in CABG Minimally Invasive Extracorporeal Circulation, Conventional Cardiopulmonary Bypass | Active not recruiting → Completed | Bursa Yuksek Ihtisas Training and Research Hospital | |
| First in Human Study of YB1-X7 Injection YB1-X7 Injection (IT), YB1-X7 Injection (IV), PD-1 inhibitor | Not yet recruiting → Recruiting | Not applicable | Shanghai Salvectors Biotechnology LTD. |
| A Preliminary Clinical Study on the Efficacy of Cyclophosphamide and Sirolimus Combined With VIC-1911 in Preventing Graft-versus-Host Disease After Haploidentical Stem Cell Transplantation in Children 1mg /kg VIC-1911 | Not yet recruiting → Recruiting | Phase 1 | Shanghai Jiao Tong University School of Medicine |
| Add-on Therapy With Low Dose Fenfluramine in Lennox Gastaut Epilepsy Fenfluramine | Unknown → Completed | Phase 2 | KU Leuven |
| When to INDuce for OverWeight? (WINDOW) Elective induction of labor at 39 gestational weeks and 0 to 3 days | Recruiting → Completed | Not applicable | University of Aarhus |
| Capillary Leak Index Versus Conventional Biomarkers in Predicting Sepsis-Related Outcomes Capillary Leak Index Versus | Recruiting → Completed | Benha University | |
| Validity and Reliability of 6 Minute Stepper Test in Kidney Transplant Recipients | Recruiting → Completed | Hacettepe University | |
| Effect of Opioid-free Anesthesia on Sleep Quality, Cognitive Function and Recovery Quality After General Anesthesia in Elderly Patients Opioid-free Analgesics, Opioid group | Unknown → Not yet recruiting | Not applicable | Beijing Friendship Hospital |
| Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease Anti-TNF therapy | Recruiting → Active not recruiting | Phase 4 | Connecticut Children's Medical Center |
| Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease Physiology-guided NCL PCI, Angiography-guided NCL PCI | Recruiting → Active not recruiting | Not applicable | Population Health Research Institute |
| Evaluation of the Predictors of Clinical and Radiological Response to Gamma-Knife Radiosurgery in the Treatment of Intermediate Ventral Nucleus of the Thalamus (VIM) Thalamotomy Tremor. gamma knife radiosurgery | Unknown → Completed | Assistance Publique Hopitaux De Marseille | |
| Promoting Active Living Among People With Advanced Cancer Acceptance- and mindfulness-based physical activity promotion | Active not recruiting → Completed | Not applicable | University of Oklahoma |
| Effect of Serotonergic Stimulation on the Gut-brain Axis serotonergic stimulation, no serotonergic stimulation | Active not recruiting → Completed | Not applicable | Örebro University, Sweden |
| Critical Appraisals at Play Competition based Education Format | Enrolling by invitation → Completed | Not applicable | Community Medical Center, Toms River, NJ |
| Advancing Clinical Heart Failure Outcomes Leveraging Defibrillation Lead Implant System for Left Bundle Branch Area Pacing LBBAP Therapy, LOT-CRT, ICD | Not yet recruiting → Recruiting | Not applicable | Medtronic Cardiac Rhythm and Heart Failure |
| Acceptability and Feasibility of an In-person 8-week Mindfulness-Based Cognitive Therapy Program Among Undergraduates Mindfulness in Students | Recruiting → Completed | Not applicable | Universidad de los Andes, Chile |
| Acceptability and Feasibility of a Universal Preventive Intervention "Universal preventive intervention for depression and anxiety for university students" | Unknown → Completed | Not applicable | Universidad de los Andes, Chile |
| The GRoceries Aimed at Increasing Nutrition Study Marketing Nudges Only, Marketing Nudges + Dynamically Adapted Financial Incentives | Recruiting → Active not recruiting | Not applicable | University of Pennsylvania |
| A Digital Twin for Exoskeleton Pilot A Digital Twin for Exoskeleton Pilot | Recruiting → Completed | Not applicable | National Taiwan University Hospital |
| Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer Trifluridine/tipiracil, Oxaliplatin | Recruiting → Suspended Interim Analysis | Phase 2 | Case Comprehensive Cancer Center |
| Residual Gastric Content and GLP-1 | Recruiting → Terminated The study was Terminated by primary investigator | University of Arkansas | |
| Post-marketing Surveillance Study for the Safety of Efluelda® Pre-filled Syringe Efluelda® Pre-filled syringe | Not yet recruiting → Recruiting | Sanofi | |
| Atezolizumab, Guadecitabine, and CDX-1401 Vaccine in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Atezolizumab, DEC-205/NY-ESO-1 Fusion Protein CDX-1401, Guadecitabine | Completed → Terminated The study was terminated due to a shortage of the drug supply. | Phase 1 / Phase 2 | National Cancer Institute (NCI) |
| Clinical Utility of Residual Hearing in the Cochlear Implant Ear Electrocochleography | Recruiting → Active not recruiting | Not applicable | Ohio State University |
| HILT vs ESWT in Supraspinatus Tendinitis High-Intensity Laser Therapy, Extracorporeal Shock Wave Therapy, Conventional Physical Therapy | Not yet recruiting → Recruiting | Not applicable | Kafrelsheikh University |
| A Pragmatic Trial With Optimized Dose of Rifampicin and Moxifloxacin for the Treatment of Drug Susceptible Pulmonary Tuberculosis Optimised rifamycin | Unknown → Completed | Phase 3 | Stellah Mpagama |
| Assessment of a Robotic Distal Gastrectomy on Non-inferiority of N2 Area Nodal Dissection Distal Gastrectomy with D2 LND | Unknown → Completed | Phase 2 | National Cancer Center, Korea |
| Testing the Youth Physical Activity Promotion Model (YPAP) in Brazilian Adolescents | Not yet recruiting → Active not recruiting | Hospital Universitario Pedro Ernesto | |
| A Study to Investigate Pharmacokinetics (PK), Safety, and Tolerability of VH4367310 in Healthy Adult Participants VH4367310, Placebo | Not yet recruiting → Recruiting | Phase 1 | ViiV Healthcare |
| Effects of Magnesium L-Threonate on Sleep, Recovery, and Athletic Performance in Collegiate Athletes Magnesium L-Threonate, Placebo | Active not recruiting → Completed | Not applicable | University of California, Los Angeles |
| HOme PElvic Floor Improvement Trainer Trial Home Pelvic Floor Trainer | Not yet recruiting → Recruiting | Not applicable | University of Colorado, Denver |
| Can Dapagliflozin Preserve Structure and Function in Transplanted Kidneys? Dapagliflozin 10mg Tab, Placebo | Recruiting → Active not recruiting | Phase 4 | Oslo University Hospital |
| A Study to Evaluate Single-dose of HB0056 in Healthy Adult Participants HB0056, Placebo | Recruiting → Completed | Phase 1 | Shanghai Huaota Biopharmaceutical Co., Ltd. |
| Pembrolizumab in the Treatment of Advanced, Progressive Adrenocortical Carcinoma. Pembrolizumab 25 MG/ML [Keytruda] | Recruiting → Active not recruiting | Phase 2 | Maria Sklodowska-Curie National Research Institute of Oncology |
| Efficacy and Safety of Baricitinib in the Post-intracerebral Hemorrhage Pulmonary Injury Baricitinib | Unknown → Active not recruiting | Phase 1 / Phase 2 | Tianjin Medical University General Hospital |
| Real-World Outcomes of Drug-Coated Balloon Angioplasty in Coronary Artery Disease Coronary Drug-Coated Balloon | Not yet recruiting → Recruiting | Kristian Rivera | |
| Feasibility Study Comparing One vs Two Probes for Thermal Ablation Among Cervical Cancer Screen Positive WLWH in C1001P-CS9 South Africa Thermal ablation (TA) with 1 probe, Thermal ablation (TA) with 2 probes | Not yet recruiting → Recruiting | Not applicable | Fred Hutchinson Cancer Center |
| Comparative Effectiveness of Available Treatments for Sinus and Ear Infections in Children (Acute Sinusitis) Amoxicillin, Amoxi Clavulanate, Amoxicillin Placebo | Not yet recruiting → Recruiting | Phase 4 | Nader Shaikh |
| A Phase I Study of VC005 Tablets in Adolescent Subjects With Severe Alopecia Areata VC005 tablets | Not yet recruiting → Recruiting | Phase 1 | Jiangsu vcare pharmaceutical technology co., LTD |
| FlexWave Trial: Efficacy of Extracorporeal Shock Wave Therapy in Post-Stroke Upper Limb Spasticity focused extracorporeal shock wave therapy (ESWT) | Recruiting → Active not recruiting | Not applicable | National Taiwan University Hospital |
| Exosomal microRNAs as a Biomarker in Panic Disorder and in Response to CBT CBT- both internet and face to face, No intervention | Unknown → Completed | Not applicable | Hebrew University of Jerusalem |
| Single-Sided Deafness and Asymmetric Hearing Loss MED-EL Cochlear Implant System | Recruiting → Active not recruiting | Not applicable | Med-El Corporation |
| Intravenous N-acetylcysteine and Oseltamivir Versus Oseltamivir in Adults Hospitalized With Influenza and Pneumonia N-acetyl cysteine, 5% Dextrose | Unknown → Recruiting | Phase 3 | Chinese University of Hong Kong |
| Identifying Individuals at Risk of Glucocorticoid-Induced Impairment of Bone Disease Prednisolone, Placebo | Active not recruiting → Completed | Phase 2 | Odense University Hospital |
| ExAblate Transcranial MRgFUS for Unilateral Pallidotomy for the Treatment of Parkinson's Disease Transcranial ExAblate | Active not recruiting → Completed | Not applicable | InSightec |
| Evaluation of the Safety and Efficacy of a Full-Body Electrostimulation Garment for Individuals With Neurological and Neuromuscular Conditions That Cause Spasticity, Hyperreflexia, and Pain Active full-body stimulation, Sham full-body stimulation | Recruiting → Active not recruiting | Not applicable | Shirley Ryan AbilityLab |
| Mineral-Infused Clothing for Recovery From Muscle Soreness and Muscle Damage After Exercise Mineral-infused garment, Non-infused control garment, Muscle-damaging eccentric exercise (drop jumps) | Not yet recruiting → Recruiting | Not applicable | StudySetGo |
| Clinical Study to Evaluate Remineralization Using an in Situ Model. Fluoride toothpaste containing 750 ppm MFP in a Dical base, Fluoride toothpaste containing 1450 ppm MFP in a Dical base, Fluoride-free toothpaste in a Dical base | Not yet recruiting → Enrolling by invitation | Phase 3 | Colgate Palmolive |
| Leveraging Interventions for Caregiver Growth, Health, Training, Empowerment and Navigation: Comparing Group Behavioral Interventions to Improve Dementia Caregiver Strain Caring Together, Savvy Caregiver | Not yet recruiting → Recruiting | Not applicable | Massachusetts General Hospital |
| The Digestion of Protein Powders in Healthy Participants Using SIMBA and LIMBA Capsule Milk Protein Concentrate, Micellar Casein Isolate | Active not recruiting → Completed | Not applicable | Nimble Science Ltd. |
| Treatment of a Single Patient With CRD-TMH-001 CRD-TMH-001 | Unknown → Completed | Phase 1 | Cure Rare Disease, Inc |
| Decentralization of Hepatitis B Care in Sub-Saharan Africa: a Pilot Program in Ethiopia Tenofovir Disoproxil Fumarate | Recruiting → Active not recruiting | Oslo University Hospital | |
| Framework for Optimizing, Refining, and Unifying Management of HSCT in Pediatric ALL Total Body Irradiation 8 Gy, Ruxolitinib, Blinatumomab | Not yet recruiting → Recruiting | Phase 2 / Phase 3 | Bambino Gesù Hospital and Research Institute |
| Inpatient Stroke Recovery Using Sensors Wearable sensors | Recruiting → Enrolling by invitation | Shirley Ryan AbilityLab | |
| SMART GOALS for Youth With Prediabetes SMART GOALS Setting Tool/ Protocol | Unknown → Recruiting | Not applicable | Northwell Health |
| Autus Valve Continued Access Study (CAS) Pulmonary Valve Replacement Surgery | Recruiting → Active not recruiting | Not applicable | Edwards Lifesciences |
| Motor Control Retraining Exercises on Shoulder Dysfunction Post Mastectomy motor control retraining exercises, traditional physical therapy for shoulder dysfunction | Recruiting → Completed | Not applicable | Cairo University |
| An Exploratory Study to Evaluate Skin Brightening Effects of Different Cosmetic Formulations on UV Irradiated Tanning Model SMR 1, SMR 2, SMR 3 | Not yet recruiting → Active not recruiting | Not applicable | Unilever R&D |
| A Trial of the Safety and Tolerability of SEP-363856 in Adults With Generalized Anxiety Disorder SEP-363856 | Not yet recruiting → Recruiting | Phase 3 | Otsuka Pharmaceutical Development & Commercialization, Inc. |
| The Efficacy of Non-invasive Brain Stimulation (NIBS) on Cognitive Functions in Patients With Chronic Obstructive Pulmonary Disease (COPD) Non-invasive brain stimulation, Sham Non-Invasive brain stimulation | Not yet recruiting → Active not recruiting | Not applicable | Ministry of Health, Kuwait |
| Combing a Deep Learning-Based Radiomics With Liquid Biopsy for Preoperative and Non-invasive Diagnosis of Glioma Prediction of glioma grading and molecular subtype | Unknown → Completed | Second Affiliated Hospital of Nanchang University | |
| COordiNated CommuNication, Education, and Care Transitions After Acute Kidney Injury (CONNECT-AKI) AKI Discharge Summary Template, Chat-Based Educational Messaging Program | Not yet recruiting → Recruiting | Not applicable | Northwell Health |
| The Mobile Health and Wellness Program Remote Health Study Remote patient monitoring, Telephone | Enrolling by invitation → Completed | Not applicable | Virginia Commonwealth University |
| Extensively Hydrolyzed Formula Growth Monitioring Study (GMS) Extensively hydrolyzed casein formula (C-eHCF), commercially available, Extensively hydrolyzed casein formula (INV-eHCF) | Not yet recruiting → Recruiting | Not applicable | Mead Johnson Nutrition |
| Long-term Safety and Efficacy of Nemolizumab With Moderate-to-severe Atopic Dermatitis Nemolizumab | Active not recruiting → Completed | Phase 3 | Galderma R&D |
| Histotripsy in Biliary Tract Cancer Gemcitabine, Cisplatin, Durvalumab | Not yet recruiting → Recruiting | Not applicable | NYU Langone Health |
| MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors LY3962673, Cetuximab, Gemcitabine | Recruiting → Active not recruiting | Phase 1 | Eli Lilly and Company |
| Phase 1 Single Ascending Doses (SAD) of M5542 in Healthy Participants M5542, Placebo | Recruiting → Suspended The study is currently paused pending a potential amendment. | Phase 1 | Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany |
| Cardiometabolic Effects of Non-Nutritive Sweeteners (NNS) in Type 1 Diabetes (T1D) Cherry Sports Drink | Not yet recruiting → Recruiting | Not applicable | Medical College of Wisconsin |
| A Study of ImmunoPet Imaging Using 89Zr-DFO-REGN5054 in Adult Participants With Solid Cancers Treated With Cemiplimab 89Zr˗DFO˗REGN5054, cemiplimab | Recruiting → Active not recruiting | Phase 1 | Regeneron Pharmaceuticals |
| Rituximab for Treatment of Checkpoint Inhibitor Induced Immune-related Adverse Events Rituximab (RTX) | Not yet recruiting → Recruiting | Phase 1 | Inge Marie Svane |
| Clinical Investigation of Oral Malodor for Max Fresh Toothpaste Containing Zinc Citrate Versus a Commercially Available Regular Fluoride Toothpaste Max Fresh Toothpaste, Colgate Cavity Protection Toothpaste | Active not recruiting → Completed | Phase 3 | Colgate Palmolive |
| Add-on Clioquinol in Drug-resistant Childhood Epilepsy: an Exploratory Study Clioquinol | Unknown → Completed | Phase 2 | KU Leuven |
| Exploratory Clinical Research for the Evaluation of Human GMP (Good Manufacturing Practice) Collagen Implants (Humabiologics) in the Treatment of Corneal Melting (RCJ-COL3D-MC-01-2026) 3D collagen implant printed under GMP conditions. | Not yet recruiting → Recruiting | Not applicable | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal |
| 8-Chloroadenosine in Combination With Venetoclax for the Treatment of Patients With Relapsed/Refractory Acute Myeloid Leukemia 8-Chloroadenosine, Venetoclax | Recruiting → Suspended Safety Issues, status is being updated per PI due to safety issues. Study is now Temporarily Closed to Accrual. | Phase 1 | City of Hope Medical Center |
| Feasibility of Integrating Olfactory Stimuli Into Virtual Reality Cue Exposure for Patients With Alcohol Dependence VR Cue-Exposure Including Olfactory Stimuli | Recruiting → Completed | Not applicable | Charite University, Berlin, Germany |
| A Study to Learn About the Single Dose Pharmacokinetics of Study Medicine Called Tilrekimig in Healthy Adults When Co-Mixed With rHuPH20 tilrekimig and rHuPH20 | Recruiting → Active not recruiting | Phase 1 | Pfizer |
| Intraoperative Monitoring to Predict Postoperative Complications After Thyroidectomy | Recruiting → Completed | Central Hospital, Nancy, France | |
| Clinical Trial of TQB3126 for Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy in Breast Cancer Subjects TQB3126 | Not yet recruiting → Recruiting | Phase 1 / Phase 2 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. |
| Validation of Insulin Dose Prediction Model Based on Artificial Intelligence Algorithm CSII in the prediction model group, CSII in the empirical group | Recruiting → Terminated Recruitment was stopped early because hospital length-of-stay constraints limited protocol delivery. The PI's decision also took account of the available non-inferiority results. | Not applicable | Sun Yat-sen University |
| Acceptability and Feasibility of Reframe-IT+U for Suicidality in University Students. Indicated Prevention for suicidality | Not yet recruiting → Completed | Not applicable | Universidad de los Andes, Chile |
| Enhancing Referral Decision-making for Advanced Treatment in Parkinson's Disease Through Objective Measurements and Patient Reported Outcomes. Neptune, Standard clinical care | Unknown → Active not recruiting | Not applicable | Copenhagen University Hospital, Rigshospitalet |
| The Study to Evaluate the Plaque Control and Anti-Gingivitis Efficacy of a Toothpaste in Chinese Population Test Toothpaste, Regular Fluoride Toothpaste | Not yet recruiting → Recruiting | Not applicable | HALEON |
| A Randomised Control Clinical Trial Investigating the Effect of H-PRF on Implant Stability and Marginal Bone Levels Horizontal platelet-rich fibrin (H-PRF) | Unknown → Completed | Not applicable | University of Dublin, Trinity College |
| Comparison of Kinesio Taping Techniques in Ulnar Nerve Entrapment Kinesio Taping with Space-Correction Technique, Kinesio Taping with Neural Technique, Sham/Placebo Taping | Not yet recruiting → Recruiting | Not applicable | Antalya Training and Research Hospital |
| Assessment of Biomarkers in Patients With Decompensated Heart Failure and Underlying Coronary Artery Disease Biomarker Assessment | Unknown → Completed | CirQuest Labs, LLC | |
| Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain SL1002, Normal Saline | Recruiting → Active not recruiting | Phase 3 | Saol Therapeutics Inc |
| Mediators of Loin Pain in IgA Nephropathy | Not yet recruiting → Enrolling by invitation | University of Leicester | |
| Anti-VEGF Therapy for Acute Thyroid Eye Disease Sub-tenon injection of saline followed by a sub-tenon injection of aflibercept, Sub-tenon injection of hyaluronidase (HA) followed by a sub-tenon injection of aflibercept, Sub-tenon injection of hyaluronidase (HA) alone | Completed → Terminated Funding prematurely ended | Phase 2 | Massachusetts Eye and Ear Infirmary |
| Whole Body HER2 Quantification With 89Zr-Trastuzumab PET/CT to Asses Zr-trastuzumab Accumulation in HER2-mutated and HER2-overexpressing Metastatic Non-small Cell Lung Cancer PET imaging with ⁸⁹Zr-trastuzumab, Blood sampling for pharmacokinetics | Not yet recruiting → Recruiting | Phase 1 | The Netherlands Cancer Institute |
| Contingency Management to Improve Medication for Opioid Use Disorder Continuation After the Emergency Department Contingency Management, Usual care as prescribed by the ED physicians | Recruiting → Completed | Not applicable | University of Vermont |
| Improving HPV Vaccination Coverage Among Adolescent Girls in Mali and Côte d'Ivoire Through Community Health Worker Follow-up HPV vaccination pro-active community-based follow-up model, Standard community mobilization | Active not recruiting → Completed | Not applicable | Arsène Brunelle Sandie |
| Comparative Effectiveness of Available Treatments for Sinus and Ear Infections in Children (Acute Otitis Media) Amoxicillin, Amoxicillin-Clavulanate, Amoxicillin Placebo | Not yet recruiting → Recruiting | Phase 4 | Nader Shaikh |
| A Study of SHR-1918 In Participants With Hypertriglyceridemia SHR-1918/ SHR-1918 placebo | Recruiting → Active not recruiting | Phase 3 | Beijing Suncadia Pharmaceuticals Co., Ltd |
| Dual Tasking Training to Enhance Self-Efficacy in Individuals With Parkinson's Disease dual tasking training | Not yet recruiting → Recruiting | Not applicable | Alvaro Reyes |
| Digital Intervention for Adults With Misophonia Acceptance and commitment therapy | Recruiting → Completed | Not applicable | Utah State University |
| Quality of Recovery After Day Care Surgery With App Controlled Remote Monitoring: a Randomized Controlled Trial Remote monitoring | Unknown → Completed | Not applicable | Onze Lieve Vrouwe Gasthuis |
| Mastering Diabetes Study Mastering Diabetes | Active not recruiting → Completed | Not applicable | Ohio University |
| Longitudinal Identity Study of Childhood Cancer Survivors Questionnaire bundle, Obtaining information from survivors' medical file | Unknown → Completed | KU Leuven | |
| The Effect of a Micro-Appreciation Intervention (Three-Things Journal Application) on Caregiver Burden, Family Functioning, and Happiness Levels for Mothers of Children With Autism Spectrum Disorder Positive Event Writing Intervention | Recruiting → Completed | Not applicable | Cukurova University |
| Evaluation of Amblyopia Protocols Using a Dichoptic Gabor Videogame Program Visionary: computer exercises using dichoptic Gabor Patches and band-filtered noise masks, Patching | Unknown → Completed | Not applicable | Hospital de Merida |
| Maxillary Arch Distalization With Infrazygomatic Crest Miniscrews for Class II Malocclusion Infrazygomatic Crest Miniscrews | Not yet recruiting → Recruiting | Not applicable | Mansoura University |
| EffecT of eARly analGesia With Erector Spinae Plane Block to Reduce Ventilation After Severe Chest Trauma ESP block | Recruiting → Completed | Not applicable | University Hospital, Grenoble |
| A Study of Radiation Dosimetry, Safety, and Tolerability of Extended Lutetium (177Lu) Vipivotide Tetraxetan Treatment in Chemo-naïve Adults With Metastatic Castration-resistant Prostate Cancer: RADIOpharmaceutical DOSimetry Evaluation (RADIODOSE) Study AAA617, Gonadotropin-releasing hormone (GnRH) analogues, Gonadotropin-releasing hormone (GnRH) antagonists | Recruiting → Active not recruiting | Phase 1 | Novartis Pharmaceuticals |
| Gastric US in ICU Patient Gastric Ultrasound | Unknown → Withdrawn Not enough resources (time and manpower) to run study. | Not applicable | Dartmouth-Hitchcock Medical Center |
| Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Intravenous Infusion for CKD AlloRx | Recruiting → Terminated Inadequate treatment response observed in preliminary data did not justify enrolling further study participants | Phase 1 | The Foundation for Orthopaedics and Regenerative Medicine |
| Morphine or Ketamine for Analgesia Ketamine hydrochloride, Morphine sulphate | Not yet recruiting → Recruiting | Phase 3 | Columbia University |
| A Study to Learn More About the Treatment of People With Congenital Thrombotic Thrombocytopenic Purpura (cTTP) Who Received Recombinant ADAMTS13 (rADAMTS13) as Part of the Early Access Program No Intervention | Not yet recruiting → Recruiting | Takeda | |
| An Open-label, Uncontrolled Study of ONO-4578 and ONO-4538 in Combination With Standard-of-care Docetaxel and Ramucirumab as Second-line Therapy in Patients With Advanced or Recurrent Non-small Cell Lung Cancer ONO-4578, ONO-4538, Docetaxel | Active not recruiting → Completed | Phase 1 | Ono Pharmaceutical Co., Ltd. |
| IMProving Adherence to Colonoscopy Through Teams and Technology BPB, No PIN, BPB, PIN, No BPB, PIN | Enrolling by invitation → Active not recruiting | Not applicable | University of California, San Francisco |
| Observational Small Intestine and Blood Fingerprint (SmIle) Study in Parkinson's Disease Fluid biopsy capsule, Levodopa-Carbidopa Immediate Release | Active not recruiting → Terminated Study recruitment phase exceeded the time allotted | Nimble Science Ltd. | |
| Comparison Between the Effects of Implantable Gestrinone and Oral Dienogest in the Treatment of Endometriosis Implantable gestrinone, Oral Dienogest | Unknown → Recruiting | Phase 4 | Bio Meds Pharmaceutica Ltda |
| A Clinical Study to Assess the Effectiveness of Use of Three Experimental Denture Adhesives Compared to Using No-Adhesive Experimental Denture Adhesive 1, Experimental Denture Adhesive 2, Experimental Denture Adhesive 3 | Recruiting → Completed | Not applicable | HALEON |
| Ovarian Cancer Screening and AI ChatGPT - Control, ChatGPT - Evidence-Based Screening Discussion | Not yet recruiting → Completed | Not applicable | Charite University, Berlin, Germany |
| Impact of Live Streaming Exercise on Liver Health in MASLD Pregnant Women Live Streaming Exercise | Not yet recruiting → Completed | Not applicable | Peking University |
| Safety of Cultured Allogeneic Adult Umbilical Cord Stem Cells for Peyronie's Disease, ED, and Interstitial Cystitis AlloRx | Recruiting → Terminated Inadequate treatment response observed in preliminary data did not justify enrolling further study participants | Phase 1 | The Foundation for Orthopaedics and Regenerative Medicine |
| Comparison of Whole Body DWI to FDG PET Fluorodeoxyglucose F18, Positron Emission Tomography combined with Magnetic resonance imaging (PET/MRI), Whole Body Magnetic Resonance Imaging with Diffusion-Weighted Imaging (WB-MRI-DWI) | Recruiting → Active not recruiting | Not applicable | University of California, San Francisco |
| Adjunctive Sirolimus and Oseltamivir Versus Oseltamivir Alone for Treatment of Influenza sirolimus and oseltamivir, Oseltamivir | Unknown → Active not recruiting | Phase 3 | Chinese University of Hong Kong |
| Lung US for PEEP Optimization in Robotic Radical Prostatectomy or Cystectomy Patients Lung Ultrasound - guided Stepwise PEEP, Standard Ventilation Protocol | Active not recruiting → Completed | Not applicable | Nazmy Edward Seif |
| A Novel Multiplex ELISA Assay for Evaluating Patients With Gross Hematuria for Bladder Cancer | Active not recruiting → Completed | Cedars-Sinai Medical Center | |
| Family Intervention to Prevent Childhood Obesity Family-Based Childhood Obesity Intervention | Recruiting → Enrolling by invitation | Not applicable | University of California, Los Angeles |
| HIFU for Treatment of Non-nodular and Recurrent BCC TOOsonix system ONE-M | Active not recruiting → Completed | Not applicable | Joergen Serup |
| A Digital Health Intervention to Improve Symptoms and Physical Activity During Breast Radiation IM@Home Program, Medical Device Usage and Evaluation, Questionnaire Administration | Active not recruiting → Completed | Not applicable | University of Washington |
| Anesthetic Sensitivity Assessed by Alpha Band Power and Its Association With Emergence Time From Sevoflurane General Anesthesia in Young Adults. Intraoperative EEG Recording | Not yet recruiting → Recruiting | University of Chile | |
| Comparison of Two Postoperative Care Strategies After Breast Surgery Patient Education, Paracetamol, Dexketoprofen | Not yet recruiting → Recruiting | Not applicable | Moumtzidou Maria Aikaterini |
| Stem Cell Therapy for Intracerebral Hemorrhage Device: Phase Ⅰ Dose Level 1, Device: Phase Ⅰ Dose Level 2, Device: Phase Ⅰ Dose Level 3 | Not yet recruiting → Recruiting | Phase 1 / Phase 2 | Tang Zhouping |
| Self-Concept Reinforcement for Early School Readiness Self-Concept Reinforcement for Early School Readiness, Reach Out and Read | Recruiting → Not yet recruiting | Not applicable | Children's Hospital Los Angeles |
| Comparison of Intertransverse Process and Erector Spinae Plane Blocks in Acute Postoperative Analgesia Management for Laparoscopic Cholecystectomy Patients Intertransverse Process Block, Erector Spinae Plane Block | Recruiting → Active not recruiting | Not applicable | Konya City Hospital |
| Invasive Decoding and Stimulation of Altered Reward Computations in Depression Patients Brain stimulation | Recruiting → Completed | Not applicable | Icahn School of Medicine at Mount Sinai |
| Sleep Quality in Adolescents With Idiopathic Scoliosis | Not yet recruiting → Recruiting | Bezmialem Vakif University | |
| Statistical Learning as a Novel Intervention for Cortical Blindness Vision Training and Learning Task | Enrolling by invitation → Active not recruiting | Not applicable | University of Rochester |
| Virtual Reality-Assisted Intraoperative Sensory Modulation on Postpartum Depression and the Kynurenine Pathway | Active not recruiting → Completed | Duzce University | |
| Brain MRF in Children, Adolescents and Young Adults With Acute Leukemia MRF with neurocognative studies | Suspended → Recruiting | Not applicable | Case Comprehensive Cancer Center |
| A Study of Trastuzumab Deruxtecan in People With Non-Small Cell Lung Cancer Trastuzumab Deruxtecan | Recruiting → Withdrawn sponsor closed study | Phase 2 | Memorial Sloan Kettering Cancer Center |
| Cisplatin-induced Cochlear and Vestibular Damage in Head and Neck Cancer | Not yet recruiting → Recruiting | Simon Jäger | |
| A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet Syndrome zorevunersen, Sham Comparator | Recruiting → Active not recruiting | Phase 3 | Stoke Therapeutics, Inc |
| The Effect of the Developed Psychological Resilience Program on Phubbing Behaviors and Communication Skills Psychological Resilience Development Program for Phubbing | Not yet recruiting → Completed | Not applicable | Eastern Mediterranean University |
| Efficacy and Safety of Oral Nicotinamide as an Adjunctive Therapy in Patients With Sepsis Nicotinamide 1000 mg | Not yet recruiting → Completed | Phase 4 | Ain Shams University |
| Effectiveness of Intraligament vs IANB Anesthesia in Children Using Electronic Syringe Electronic Syringe Intraligament Technique, Electronic syringe IANB Technique | Recruiting → Completed | Not applicable | Latakia University |
| The BALANCE Study - Improving Glucose Control Through Prebiotic Gut Health Drink in Postmenopausal Women ió everyday (a prebiotic- enriched gut health drink containing inulin), Placebo Comparator | Not yet recruiting → Completed | Not applicable | University of Roehampton |
| Treatment of Rotator Cuff Tears With Platelet Rich Plasma Platelet Rich Plasma (PRP) | Withdrawn → Completed | Not applicable | The Foundation for Orthopaedics and Regenerative Medicine |
| Evaluating the Response of the Immune System of People With Long COVID (Post SARS-CoV-2) | Unknown → Completed | Huntington Memorial Hospital | |
| FMT for Pediatric SR-aGVHD Fecal Microbial Transplantation | Not yet recruiting → Recruiting | Phase 1 / Phase 2 | Bambino Gesù Hospital and Research Institute |
| Effectiveness and Implementation Evaluation of NeoMayor for Improving Cardiovascular Health in Chilean Older Adults NeoMayor App, Wearable Device Support, Human Health Coach Support | Not yet recruiting → Recruiting | Not applicable | University of Chile |
| Evaluation of Structural and Functional Integrity of the Rotator Cuff After Total Shoulder Arthroplasty CT scan of the shoulders | Recruiting → Terminated low enrollment | Not applicable | Milton S. Hershey Medical Center |
| RAD 1802: Pilot Trial of Five Fraction Stereotactic Body Radiotherapy for Early Stage Breast Cancer Patients Eligible for Post-Operative Accelerated Partial Breast Irradiation (APBI) 5 Fraction Stereotactic Body Radiation Therapy | Recruiting → Active not recruiting | Not applicable | University of Alabama at Birmingham |
| 225 IU Versus 300 IU Starting FSH Dose in PPOS for Good-Prognosis Women Follitropin Alfa (Follitrope) | Not yet recruiting → Recruiting | Not applicable | Vietnam Military Medical University |
| Development of Endoscopic Treatment for Achalasia POEM | Active not recruiting → Completed | Not applicable | Karolinska Institutet |
| Telaglenastat + Talazoparib In Prostate Cancer Telaglenastat, Talazoparib | Unknown → Withdrawn Calithera pulled out of this trial. | Phase 2 | Massachusetts General Hospital |
| Durvalumab as Consolidation Therapy in Patients With LS-SCLC Following sCRT | Recruiting → Completed | The First Affiliated Hospital with Nanjing Medical University | |
| Effect of Food-derived Active Components on Digestive Tract Health in Adults With Irritable Bowel Syndrome Prebiotic_L, resveratrol_L, Prebiotic_M | Not yet recruiting → Completed | Not applicable | Peking University |
| Impact of Metformin on Immuno-virologic Parameters in HIV Metformin | Recruiting → Terminated During the COVID pandemic, our IRB halted enrollment into the study among other changes. Post COVID it was decided that too long an interval between patient enrollment was problematic for the study and a discussion was made to terminate. | Phase 2 / Phase 3 | University of Hawaii |
| Effects of Blood Flow Restriction Training on Physical Function, Muscle Adaptations, and Performance in Roller Skaters Blood Flow Restriction Roller Skating Training, Standardized Roller Skating Training | Not yet recruiting → Active not recruiting | Not applicable | Shanghai University of Sport |
| A Study of of HOT1030 in Patients With Advanced Solid Tumors HOT-1030 | Unknown → Completed | Phase 1 | Huabo Biopharm Co., Ltd. |
| Sodium Oxybate for Postoperative Sleep Disturbance After Thoracic Surgery sodium oxybate, Placebo | Not yet recruiting → Recruiting | Not applicable | Jingsheng Lou |
| A Study Evaluating the Safety of Inavolisib and Fulvestrant With or Without Palbociclib in Participants With Advanced Breast Cancer (ABC) and Type 2 Diabetes Inavolisib, Fulvestrant, Palbociclib | Not yet recruiting → Recruiting | Phase 2 | Hoffmann-La Roche |
| Acceptability and Feasibility of an 8-week Online Mindfulness-Based Cognitive Therapy Program Among Undergraduate Students Mindfulness-Based Cognitive Therapy | Unknown → Completed | Not applicable | Universidad de los Andes, Chile |
| Bexmarilimab + Azacitidine Versus Placebo + Azacitidine in Participants With Treatment-naïve Higher-risk Myelodysplastic Syndromes bexmarilimab (1mg/kg), azacitidine, Placebo | Not yet recruiting → Recruiting | Phase 2 | Faron Pharmaceuticals Ltd |
| Evaluating a School-based Social and Material Needs Identification System to Prevent Youth Violence Involvement Pathways to Potential | Active not recruiting → Completed | University of Michigan | |
| Study of the Effect of Haemodialysis on the Pharmacokinetics, Safety, and Tolerability of Balcinrenone/Dapagliflozin Balcinrenone/dapagliflozin | Recruiting → Completed | Phase 1 | AstraZeneca |
| Effect of Ice Pack and Warm Gel Pad Use During Drain Removal on Anxiety, Comfort, Physiological Parameters, and Patient Satisfaction Undergoing Open Urological Surgery Ice Pack, Warm Gel Pad Group | Recruiting → Completed | Not applicable | Tarsus University |
| Pilot Study of Anesthesiologists' Preoperative Prediction of Postoperative Intensive Care Unit Admission Preoperative Clinical Prediction of Postoperative ICU Admission | Recruiting → Completed | Van Training and Research Hospital | |
| IgG Binding Protein LT in Support of a Healthy Gut on the Go IgG Binding Protein LT, Placebo | Not yet recruiting → Recruiting | Not applicable | Bactolife A/S |
| A Trial of HRS-1780 in Participants With Uncontrolled Hypertension or Resistant Hypertension. HRS-1780 tablet, HRS-1780 tablet placebo | Not yet recruiting → Recruiting | Phase 2 / Phase 3 | Shandong Suncadia Medicine Co., Ltd. |
| The TearAD Study: Tear Biomarkers for Alzheimer's Disease (AD) Screening and Diagnosis Tear Fluid collection (Schirmer's strip), Retinal imaging | Unknown → Completed | Maastricht University Medical Center | |
| Neurocognitive Factors in EdTech Intervention Response GraphoLearn reading intervention, Math control intervention | Active not recruiting → Completed | Not applicable | University of Connecticut |
| PROACT AYA: Preventing Overweight/Obesity-Associated Cardiotoxicity With Tirzepatide In Adolescent And Young Adult Cancer Survivors - A Phase 2 Single-Arm, Single-Center Feasibility Study Tirzepatide | Not yet recruiting → Recruiting | Phase 2 | M.D. Anderson Cancer Center |
| Measuring Corneal Parameters Investigational device, Comparator device | Recruiting → Completed | Not applicable | Icare Finland Oy |
| Multinational Phase II Trial to Compare Safety and Efficacy of SIRT (Y-90 Resin Microspheres) Followed by Atezolizumab Plus Bevacizumab, vs SIRT (SIRT-Y90) Followed by Placebo in Locally Advanced HCC Patients SIRT-Y90 with Atezolizumab + Bevacizumab, SIRT-Y90 with Placebo (IV) | Recruiting → Active not recruiting | Phase 2 | National Cancer Centre, Singapore |
| Head and Neck Squamous Cell Carcinoma (HNSCC)PET-CT Pilot Study 18-F FDG | Recruiting → Completed | Not applicable | University Health Network, Toronto |
| An Observational, Prospective, Multicenter Study to Evaluate the Biologic Use and Outcomes in Chinese Asthma Patients | Active not recruiting → Completed | AstraZeneca | |
| Transcranial Ultrasonography for the Management of Patients With Mild TBI Transcranial Doppler (TCD) | Active not recruiting → Completed | Not applicable | University Hospital, Grenoble |
| CEB-01 in Pediatrics With Locally Resectable Abdominal Tumors Standard surgery, CEB-01 | Recruiting → Active not recruiting | Phase 2 | CEBIOTEX |
| Prevalence of Non-alcoholic Fatty Liver Disease Among Non-obese Obstructive Sleep Apnea by Using Transient Elastography | Unknown → Completed | Chinese University of Hong Kong | |
| A Study of RO7830698 in Healthy Participants and Participants With Chronic Obstructive Pulmonary Disease RO7830698, Placebo | Not yet recruiting → Recruiting | Phase 1 / Phase 2 | Hoffmann-La Roche |
| Nirogacestat in Patients With Kaposi Sarcoma Biospecimen Collection, Chest Radiography, Computed Tomography | Not yet recruiting → Recruiting | Phase 2 | AIDS Malignancy Consortium |
| PrEcision Pacing in HFpEF: the PEP-HFpEF Trial Individualized myPACE pacemaker programming | Not yet recruiting → Recruiting | Not applicable | Tufts Medical Center |
| A Bifido Bacteria to Improve Lactose Digestion and Tolerance Bifidobacterium adolescentis IVS-1 capsule, Placebo cellulose capsule | Unknown → Completed | Not applicable | Purdue University |
| A Study to Test the Safety and Effects of Inhaled GDC-6988 in Participants With Muco-obstructive Disease GDC-6988 | Recruiting → Terminated Sponsor's Decision | Phase 1 | Genentech, Inc. |
| eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Cancer Pre-Test Intervention, Standard of Care, Post-Test Intervention | Recruiting → Active not recruiting | Not applicable | Abramson Cancer Center at Penn Medicine |
| A Study to Evaluate INCB099280 in Participants With Select Solid Tumors Who Are Immune Checkpoint Inhibitor Naive INCB099280 | Active not recruiting → Terminated This was a strategic business decision. There were no safety concerns contributing to this decision. | Phase 2 | Incyte Corporation |
| Improving Speech in Noise Perception for Individuals With Age-related Hearing Loss transcutaneous auricular vagus nerve stimulation, Sham Control | Recruiting → Completed | Not applicable | University of Florida |
| A Study to Evaluate INCB099280 in Participants With Advanced Cutaneous Squamous Cell Carcinoma INCB099280 | Active not recruiting → Terminated This was a strategic business decision. There were no safety concerns contributing to this decision. | Phase 2 | Incyte Corporation |
| Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015) Tulisokibart, Placebo | Recruiting → Active not recruiting | Phase 2 | Merck Sharp & Dohme LLC |
| Functional Cure Rate of Peg-IFNα-2b Combined With TAF in HBeAg Negative CHB Patients PEG IFN α-2b; TAF | Unknown → Completed | Not applicable | Huashan Hospital |
| Efficacy and Safety of Fruquintinib in Combination With Sintilimab in Advanced Renal Cell Carcinoma (FRUSICA-2) fruquintinib+sintilimab, axitinib / everolimus, fruquintinib | Active not recruiting → Completed | Phase 2 / Phase 3 | Hutchmed |
| Retrospective Observational Study of Implant-supported Restorations With Dental Implants. Dental Implants installed in an grafted area (sinus lifting), Dental Implants installed in an grafted area (ridge augmentation), Dental Implants installed in an grafted area (extraction sites) | Unknown → Terminated The study was not terminated because we changed the methodology of the patient recruitment | Not applicable | M3 Health |
| CM for Patients With ALD After Liver Transplant Contingency Management | Active not recruiting → Completed | Not applicable | Arpan A. Patel, MD |
| Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic Cancer Biopsy Procedure, Biospecimen Collection, Computed Tomography | Recruiting → Suspended Other - DSMB decision | Phase 1 / Phase 2 | National Cancer Institute (NCI) |
| Assessment of PK Similarity of FYB206 in Comparison With Keytruda in Resected Stage II or III Melanoma Patients FYB206, Keytruda | Active not recruiting → Completed | Phase 1 | Formycon AG |
| Cross-sectional Study of Sleep Disturbance in Hong Kong Children With Cancer Comparing With Healthy Counterparts and Children With Other Chronic Diseases | Recruiting → Completed | Chinese University of Hong Kong | |
| A Study of ES102 in Combination With Toripalimab in Subjects With Advanced Non-small Cell Lung Cancer ES102, Toripalimab | Recruiting → Active not recruiting | Phase 2 | Elpiscience (Suzhou) Biopharma, Ltd. |
| Exploring the Relationship Between Caring Experience, Perceived Behavioral Control, and Caring Intention Among Students | Recruiting → Completed | Chiu Shu-Ching | |
| Neuroscience-Based Exercise Training in Female Volleyball Players Exercise | Recruiting → Completed | Not applicable | Özge Ecem Şenel |
| Hyperlipoproteinemia A as a Marker of Cardiovascular Risk in Patients With Stage 4 Chronic Kidney Disease lipoprotein A level dosing | Not yet recruiting → Recruiting | Centre Hospitalier Universitaire de Nīmes | |
| Two Tutorial Action Programs, Incidental and Structured, on the General Welfare of Elementary School Students. Structured emotional education program (PEE), Incidental tutorial action based on the school's regular curriculum (PCO) | Unknown → Completed | Not applicable | OIHANA SAGASTI ARRIEN |
| Cytomegalovirus Reactivation in ICU Patients Requiring Prolong Mechanical Ventilation | Unknown → Completed | Sanjay Gandhi Postgraduate Institute of Medical Sciences | |
| Feasibility Study Comparing Use of One Or Two Probes for Thermal Ablation Among Screen Positive Women Living With HIV in C1001P-CS2 Kenya Thermal ablation (TA) with 1 probe, Thermal ablation (TA) with 2 probes | Not yet recruiting → Recruiting | Not applicable | Fred Hutchinson Cancer Center |
| Narrow Excision Versus Wide Excision for the Treatment of Adults With Invasive Cutaneous Melanoma, ICEMAN Trial Biospecimen Collection, Excision, Survey Administration | Recruiting → Suspended Pending coordinating center transition | Not applicable | OHSU Knight Cancer Institute |
| Acute Effects of a Urate-lowering Bacterial Therapeutic on Small Intestinal Transcriptomics and Glycomics in Healthy Subjects BEO001 Probiotic, BEO001 Probiotic + Beta-Glucan, Placebo | Not yet recruiting → Active not recruiting | Not applicable | Örebro University, Sweden |
| Investigate the Efficacy and Safety of BRII-835 (VIR-2218) and PEG-IFNα Combination Therapy in Chronic HBV Patients PEG-IFNα, BRII-835 | Active not recruiting → Completed | Phase 2 | Brii Biosciences Limited |
| Clinical Study on Circadian Genes Dysregulation in Patients With Glucocorticoid Disorders circadian gene expression evaluation | Unknown → Recruiting | Not applicable | University of Roma La Sapienza |
| A Study of IBI362 in Participants With Metabolic Dysfunction-Associated Steatohepatitis (MASH) Placebo, IBI362 | Recruiting → Active not recruiting | Phase 2 | Innovent Biologics (Suzhou) Co. Ltd. |
| TNF-α Treatment of Blast-Induced Tinnitus Etanercept, Saline | Recruiting → Active not recruiting | Phase 2 | Wayne State University |
| Safety of CRT100 on Treatment Spinal Cord Injury CRT100 | Not yet recruiting → Recruiting | Phase 1 | Cristália Produtos Químicos Farmacêuticos Ltda. |
| Effect of Stress Ball Application During Coronary Angiography on Anxiety, Procedure-related Fear, Physiological Parameters, and Comfort Stress ball | Not yet recruiting → Recruiting | Not applicable | Tarsus University |
| Hospital Airway Resuscitation Trial A strategy of first choice supraglottic airway, A strategy of first choice endotracheal intubation | Recruiting → Completed | Not applicable | Montefiore Medical Center |
| A Study to Learn How the Study Medicine Called Etrasimod is Taken up Into Blood and Breastmilk of Healthy Breastfeeding Women Etrasimod | Active not recruiting → Completed | Phase 1 | Pfizer |
| Bicuspid Aortic Valve (BAV) Registry | Recruiting → Enrolling by invitation | University of Michigan | |
| Outpatient Management of Primary Spontaneous Pneumothorax: Pigtail Catheter With Unidirectional Valve vs. Exsufflation, Randomized Prospective Study Fuhrman catheter insertion, Three-way stopcock open, Manual aspiration | Recruiting → Active not recruiting | Not applicable | Rennes University Hospital |
| Radical Prostatectomy Without Prior Biopsy Transperineal Fusion-Targeted Prostate Biopsy With Intraoperative Frozen Section Examination, Robot-Assisted Radical Prostatectomy With Pelvic Lymph Node Dissection, Standard Transperineal Fusion Prostate Biopsy | Not yet recruiting → Recruiting | Not applicable | Botkin Hospital |
| Effect of Music Therapy Applied During Lumbar Puncture on Infants' Pain Perception music | Enrolling by invitation → Completed | Not applicable | Erzurum Technical University |
| Managed Access Programs for TQJ230, Pelacarsen Pelacarsen | Available → No longer available | Novartis Pharmaceuticals | |
| Atezolizumab + Cabozantinib in Patients w/ Metastatic, Refractory Pancreatic Cancer Cabozantinib + Atezolizumab | Active not recruiting → Completed | Phase 2 | University of Arizona |
| Guided Bone Regeneration Using Polydioxanone (PDO) Membrane in Sockets After Tooth Extraction Plenum® Guide, Plenum® Oss, Tooth extraction | Unknown → Recruiting | Not applicable | M3 Health |
| The Impact of Soft Contact Lenses on the Corneal Neuromediators and Optical Quality in High Myopia Prior to SMILE This study does not involve any interventions | Recruiting → Completed | yuhao shao | |
| Ultrasound-Guided Repeated Saline Injections to Prevent and Treat Tendon Adhesions After Hand Tendon Repair Ultrasound-Guided Repeated Normal Saline Injections | Not yet recruiting → Recruiting | Not applicable | Kai Wang |
| Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for IPF AlloRx | Recruiting → Terminated Inadequate treatment response observed in preliminary data did not justify enrolling further study participants | Phase 1 | The Foundation for Orthopaedics and Regenerative Medicine |
| Primary Prevention of Cardiovascular Disease Among Female Hospital Employees: The Heart Smart for Women Intervention Heart Smart Interventional Program | Unknown → Completed | Not applicable | Northwell Health |
| Comparing the Adaptation of Commercial Milk and A2 Milk in Lactose Maldigesters Milk containing A1 and A2 beta-casein, Milk containing only A2 beta-casein | Unknown → Completed | Not applicable | Purdue University |
| A Study to Assess Intravenous ABBV-1480 Combined With Chemotherapy Versus Pembrolizumab Combined With Chemotherapy for the First Line Treatment of Locally Advanced/Metastatic Non-Small Cell Lung Cancer in Adult Participants ABBV-1480, Pembrolizumab, Carboplatin | Not yet recruiting → Recruiting | Phase 3 | AbbVie |
| In Vivo Imaging of the Olfactory Epithelium Using Confocal Laser Endomicroscopy CONVIVO system, Fluorescein injection, USP 10% | Active not recruiting → Not yet recruiting | Early Phase 1 | Dartmouth-Hitchcock Medical Center |
| Pulsed Lavage in Implant-Based Breast Reconstruction Pulsed Lavage Washout, Implant-based breast reconstruction, Bilateral or unilateral mastectomy | Recruiting → Terminated Changes in personnel | Not applicable | University of Alabama at Birmingham |
| Multimodal Intervention for Weight Management and Health in the Elderly Population Nutritional guidance focused on adopting a high-protein diet., Group Cognitive Behavioral Therapy Intervention, Resistance Training Program | Not yet recruiting → Recruiting | Not applicable | Universidade Cesumar (UNICESUMAR) |
| Plenum® Osshp in Maxillary Sinus Elevation Surgery Group 1: Autogenous bone graft, Group 2: Plenum® Osshp, Group 3: Plenum® Osshp; + i-PRF | Unknown → Completed | Not applicable | M3 Health |
| Is Our Microbiome a Predictor of Cardiac Risk | Enrolling by invitation → Suspended Reorganizing study personnel and funding | Mayo Clinic | |
| Safety and Efficacy Study of Safusidenib in Participants With IDH1-Mutant Glioma Who Discontinued Vorasidenib Treatment Due to Progressive Disease Safusidenib | Not yet recruiting → Recruiting | Phase 2 | Nuvation Bio Inc. |
| PSMA PET Combined With MRI for the Detection of PCa 68Ga-PSMA-11 | Recruiting → Active not recruiting | Phase 3 | Telix Pharmaceuticals (Innovations) Pty Limited |
| Therapeutic Support to Strengthen Dignity, Mental Well-being and Quality of Life in Acute Palliative Care Patients. Therapeutic support, Standard Specialized Palliative Consultation Service | Unknown → Completed | Not applicable | University Hospital, Basel, Switzerland |
| Prospective Validation of Adaptive Radiotherapy (ART) in Patients With Head and Neck Tumors Adaptive Radiotherapy | Recruiting → Completed | Not applicable | University Hospital, Essen |
| Adaptive Radiotherapy in Head and Neck Tumor Patients Adaptive Radiotherapy, image guided radiotherapy without online adaptation | Recruiting → Completed | Not applicable | University Hospital, Essen |
| Dynamic Airway CT is Diagnostic for Tracheomalacia in Children Dynamic Airway CT scan (DA-CT) | Recruiting → Completed | Not applicable | NYU Langone Health |
| Celiac Disease in Childhood-Adulthood Transition CeliCAT form | Enrolling by invitation → Active not recruiting | Not applicable | Tampere University Hospital |
| THE IMPACT OF WHATSAPP BASED EX-PLISSIT MODEL SEXUAL COUNSELING ON THE SEXUAL LIVES OF BREAST CANCER SURVIVORS Sexual counseling group based on the EX-PLISSIT Model | Active not recruiting → Completed | Not applicable | Karamanoğlu Mehmetbey University |
| Clinical Evaluation of Short Dentin Etching Resin composite restoration bonded using universal adhesive in etch and rinse mode (15 seconds etching), Resin composite restoration bonded using universal adhesive in etch and rinse mode (5 seconds etching), Resin composite restoration bonded using universal adhesive in self-etch mode | Recruiting → Active not recruiting | Not applicable | Mansoura University |
| Antegrade Autologous Blood Reinfusion After CPB Antegrade Pump Blood Reinfusion, No Anterograde Pump Blood Reinfusion | Recruiting → Completed | Kocaeli City Hospital | |
| EHR Precision Drug Treatment in Neonates | Unknown → Completed | Children's Hospital Medical Center, Cincinnati | |
| The Critical Link Between Gut Microbiome Dysfunction, Cravings and Relapse: RECLAIM-GUT TRIAL Personalized prebiotic dietary Formulation 2, Personalized prebiotic dietary Formulation 3, Personalized prebiotic dietary Formulation 1 | Active not recruiting → Completed | Not applicable | University of Roehampton |
| Effectiveness of the Self-Control Module of a Positive Mental Health Promotion Programme for Adult Informal Caregivers of People With Dementia: Protocol for a Randomised Controlled Trial Mentis Plus+ Caregivers | Recruiting → Active not recruiting | Not applicable | University Rovira i Virgili |
| Effect of Preoperative Diet on Perioperative Gut Microbiome high-fiber, fermented | Unknown → Completed | Not applicable | Stanford University |
| Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell IV Infusion for Systemic Sclerosis AlloRx | Recruiting → Terminated Inadequate treatment response observed in preliminary data did not justify enrolling further study participants | Phase 1 | The Foundation for Orthopaedics and Regenerative Medicine |
| Prevention of Functional and Cognitive Impairment Through a Multicomponent Exercise Program in Hospitalized Older Adults Exercise | Recruiting → Completed | Not applicable | Fundacion Miguel Servet |
| Volume Kinetics of Fluid Resuscitation in Early Sepsis Ringer's Lactate | Recruiting → Completed | Institutul de Urgenţă pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu | |
| Berzosertib and Irinotecan in Treating Patients With Progressive, Metastatic, or Unresectable TP53 Mutant Gastric or Gastroesophageal Junction Cancer Berzosertib, Computed Tomography Assisted Biopsy, Endoscopic Biopsy | Active not recruiting → Completed | Phase 2 | National Cancer Institute (NCI) |
| Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) for the Treatment of Patients With Progressing Metastatic Neuroendocrine Carcinomas Biospecimen Collection, Computed Tomography, Incomplete Freund''s Adjuvant | Suspended → Not yet recruiting | Phase 2 | Roswell Park Cancer Institute |
| Improving Medication Management in World Trade Center Responders Educational brochure for deprescribing | Recruiting → Active not recruiting | Not applicable | Icahn School of Medicine at Mount Sinai |
| Surgical Ergonomics in OBGYN Surgical Ergonomics Lecture, Pre-Incision Surgical Ergonomics Time Out, Intra-operative stretch breaks | Not yet recruiting → Recruiting | Not applicable | University Hospitals Cleveland Medical Center |
| Transcranial Doppler as a Predictor of Postoperative Cognitive Dysfunction Following Cardiopulmonary Bypass Transcranial Doppler measurement of the middle cerebral artery | Recruiting → Completed | Bakirkoy Dr. Sadi Konuk Research and Training Hospital | |
| Baroloop Multicenter Trial (Baroloop MCT) baroloop system | Recruiting → Terminated Terminated following a device deficiency in 1 subject. Benefit-risk and development assessments did not support continuation within the planned framework. Root cause analysis pending. | Not applicable | neuroloop GmbH |
| Optimization of Surgical Treatment of Patients With Incisional Ventral Hernias A new method of repair of the abdominal wall of mid-lateral postoperative ventral hernias | Recruiting → Completed | Not applicable | Samara State Medical University |
| Genetic and Physical Study of Childhood Nerve and Muscle Disorders | Active not recruiting → Completed | National Institute of Neurological Disorders and Stroke (NINDS) | |
| Adaptive Radiotherapy in Patients With Gynecological Tumors Adaptive Radiotherapy | Recruiting → Completed | Not applicable | University Hospital, Essen |
| A Comprehensive Group Intervention for Psychosocial Personnel at Risk of Stress and Moral Injury CARE MI, TAU: Treatment as usual | Enrolling by invitation → Completed | Not applicable | Universidad Complutense de Madrid |
| A Study of Inlexisertib (DCC-3116) in Combination With Anticancer Therapies in Participants With Advanced Malignancies Inlexisertib, Ripretinib | Recruiting → Active not recruiting | Phase 1 / Phase 2 | Deciphera Pharmaceuticals, LLC |
| HRS-7450 Injection Phase II Clinical Trial for Acute Ischemic Stroke. HRS-7450 Injection, HRS-7450 Injection Placebo | Active not recruiting → Completed | Phase 2 | Fujian Shengdi Pharmaceutical Co., Ltd. |
| A Phase 2 Trial to Investigate Efficacy and Safety of Vipoglanstat in Women With Endometriosis Vipoglanstat, Placebo | Recruiting → Active not recruiting | Phase 2 | Gesynta Pharma AB |
| The Effect of Yoga Applied to Primiparous Pregnant Women on Postpartum Depression and Maternal Attachment prenatal yoga | Active not recruiting → Completed | Not applicable | Muş Alparslan University |
| Administration of High Doses of Antiretroviral Drugs to Eliminate the Latent HIV-1 Reservoir Standardised triple antiretroviral therapy, High doses Triple therapy antiretroviral drugs | Recruiting → Active not recruiting | Phase 2 | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal |
| NMR Based Metabolomics Kinetics in ARDS Patients | Recruiting → Completed | Sanjay Gandhi Postgraduate Institute of Medical Sciences | |
| First-in-Human Safety and Tolerability Study of OPF-110 in Healthy Adults OPF-110, SMOFLIPID | Recruiting → Active not recruiting | Phase 1 | Otsuka Pharmaceutical Factory, Inc. |
| TMS + Exposure Therapy for Pediatric OCD: Second Phase Transcranial Magnetic Stimulation: continuous theta burst to pre supplementary motor area, Transcranial Magnetic Stimulation: Sham, Exposure with Response Prevention | Not yet recruiting → Recruiting | Not applicable | Bradley Hospital |
| Nurse-supported Mobile App for Self-help CBT-I in Informal Cancer Caregivers Nurse-Supported Mobile App for Self-Help CBT-I, Sleep hygiene education | Recruiting → Completed | Not applicable | The University of Hong Kong |
| A Study of Daily Rifapentine Combined With Isoniazid (1HP) for Tuberculosis Prevention in Children Less Than 13 Years of Age With and Without HIV Rifapentine, Isoniazid, Dolutegravir | Not yet recruiting → Recruiting | Phase 1 / Phase 2 | National Institute of Allergy and Infectious Diseases (NIAID) |
| Prospective Trial of [18F]AlF-FAPI-74 for PET Imaging of Fibroblast Activation Protein in Patients With Endometriosis [18F]AlF-FAPI-74 PET/CT | Not yet recruiting → Recruiting | Not applicable | Universitaire Ziekenhuizen KU Leuven |
| Golimumab and Apalutamide for the Treatment of Castration-Resistant Prostate Cancer, TRAMP Study Apalutamide, Biopsy, Biospecimen Collection | Active not recruiting → Terminated The trial was ended sooner than expected due to a combination of factors, including slow accrual, lower than anticipated benefit to patients, and loss of funding from the study sponsor. | Phase 2 | University of Washington |
| Blood-Brain Barrier Disruption Using Transcranial MRI-Guided Focused Ultrasound Transcranial ExABlate | Active not recruiting → Completed | Not applicable | InSightec |
| The Effect of Exercise on Motion Perception and Fear in Low Back Pain Exercises | Unknown → Completed | Not applicable | Suleyman Demirel University |
| Neuro-MoD: Neuroplasticity With Motor Development Constraint-Induced Movement Therapy (CIMT), Transcutaneous auricular vagus nerve stimulation (taVNS) | Not yet recruiting → Recruiting | Not applicable | University of Wisconsin, Madison |
| Study Evaluating the Safety and Feasibility of Panitumumab-IRDye800 and [18F]NOTA-ABY-030 for Targeted Dual-Modality Imaging (TDMI) in Head and Neck Squamous Cell Carcinoma Panitumumab-IRDye800, [18F]NOTA-ABY-030 | Not yet recruiting → Recruiting | Phase 1 | Vanderbilt-Ingram Cancer Center |
| TMS + Exposure Therapy for Pediatric OCD Transcranial Magnetic Stimulation: intermittent theta burst to dorsolateral prefrontal cortex, Exposure with Response Prevention, Transcranial Magnetic Stimulation: Sham | Recruiting → Completed | Not applicable | Bradley Hospital |
| Balance Rehabilitation Based on Serious Games Experimental: Interactive balance rehabilitation based on serious games., Active Comparator: conventional balance rehabilitation without the use of technological devices. | Recruiting → Completed | Not applicable | IRCCS San Raffaele Roma |
| Improving Student Mental Health Through a Universal Trauma-Informed Intervention RAP Club Delivered by a School Clinician, RAP Club Delivered by a Teacher, Standard Supervision | Not yet recruiting → Recruiting | Not applicable | Johns Hopkins Bloomberg School of Public Health |
| Radial Versus Femoral Secondary Access in Patients Undergoing TAVI Radial TAVI, femoral TAVI | Recruiting → Active not recruiting | Not applicable | University Heart Center Freiburg - Bad Krozingen |
| Evaluation of Diagnostic Accuracy of MCG(Magnetocardiography) Scan in Suspected Coronary Artery Disease Rest/Stress MCG scan, Rest MCG scan | Unknown → Completed | AMCG | |
| Distribution of the Homologous Recombination-related (HRR) Genesmutationsand HRD in Breast Cancer Standard Management | Recruiting → Active not recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | |
| Access to EyeGlasses for School-aged Children Fitz Frames 3-D Printed Glasses | Unknown → Terminated Funding was stopped from source before project could start intervention phase of trial | Not applicable | Boston Children's Hospital |
| Evaluate Pathogens and Immunity to Acute Otitis Media in Healthy Children. procedures | Unknown → Active not recruiting | Rochester General Hospital | |
| Pyronaridine in Acute Myeloid Leukemia (AML) Pyronaridine Tetraphosphate | Unknown → Suspended Change of protocol | Phase 2 | Armaceutica, Inc. |
| OMNI 3.1 Surgical System in Subjects With Primary Open-Angle Glaucoma OMNI 3.0 Surgical System | Recruiting → Active not recruiting | Not applicable | Sight Sciences, Inc. |
| GnRH for Luteal Support in IVF/ICSI/FET Cycles GnRH, placebo | Recruiting → Active not recruiting | Phase 4 | University Reproductive Associates |
| Examining Digital Health Care Delivery Models Through Medicaid Collaborative digital health delivered multicomponent intervention | Recruiting → Active not recruiting | OSF Healthcare System | |
| Impact of B. Adolescentis iVS-1 Probiotic on Gastrointestinal Outcomes Probiotic, Placebo | Active not recruiting → Completed | Not applicable | Synbiotic Health |
| Registry Study of Assistive Devices, Medicines and Healthcare Measures in ALS, SMA and Other Neurological Diseases. | Recruiting → Completed | Ambulanzpartner Soziotechnologie APST GmbH | |
| Study in Human iPSCs-derived RPE Cells Transplantation for Advanced (Late-stage) AMD hiPSC-RPEs | Not yet recruiting → Recruiting | Phase 1 / Phase 2 | The First Affiliated Hospital with Nanjing Medical University |
| The Role of Peripheral Afferents in Modulating Post-stroke Central Pain Lidocaine 20mg/ml, Levobupivacaine Hydrochloride 1.25 MG/ML, Sodium Chloride 0.9% Inj | Recruiting → Completed | Phase 3 | Institut National de la Santé Et de la Recherche Médicale, France |
| Nellcor™ Investigational Device Sitting-Walking Study | Not yet recruiting → Recruiting | Medtronic - MITG | |
| Time-restricted Eating Acceptability, Efficacy and Safety in Obesity Time Restricted Eating | Recruiting → Completed | Not applicable | University of Mississippi, Oxford |
| Opioid Treatment and Peer Recovery Support Core Intervention, Peer Support Specialists (PSS), Treatment as Usual (TAU) | Recruiting → Completed | Not applicable | Brown University |
| Evaluating the Community Drum Circle Communal Drumming, Communal drumming recordings | Enrolling by invitation → Completed | Not applicable | Yale University |
| Improving Jail Response to the Overdose Crisis: A Hybrid Trial of Jail ECHO to Improve MOUD Implementation and Public Health Outcomes Project ECHO | Not yet recruiting → Recruiting | Not applicable | University of Massachusetts, Worcester |
| Application of Remimazolam Combined With Esketamine in Painless Gastroscopy and Colonoscopy in Elderly Patients remimazolam-remifentanil, remimazolam-esketamine | Recruiting → Active not recruiting | Not applicable | Harbin Medical University |
| Upper Limb Rehabilitation in People With Parkinson's Disease: Experimental Group, control group | Recruiting → Completed | Not applicable | IRCCS San Raffaele Roma |
| Drum Circle Synchrony Study 2c.a. Communal drumming recordings | Enrolling by invitation → Completed | Not applicable | Yale University |
| Mindfulness in a College Physiology Course Biology Course with Integrated Mindfulness | Enrolling by invitation → Completed | Not applicable | Trustees of Dartmouth College |
| Effect of Sensorimotor Training on Pain and Gait Performance in Patients With Discogenic Sciatica Standard physical therapy, Sensorimotor Training | Not yet recruiting → Recruiting | Not applicable | Cairo University |
| Antiviral Long Acting Drugs Landing in People Living With HIV Surveys completion, Home administration of CAB+RPV, Hospital administration of CAB+RPV | Active not recruiting → Completed | Not applicable | IRCCS San Raffaele |
| Premixed Glucagon/Insulin Solution for Faster Insulin Absorption in Type 1 Diabetes Lyumjev 100 UNT/ML Injectable Solution, Premixed Lyumjev | Suspended → Terminated The study was terminated due toa combination of: 1. At best minimal effect on insulin absorption 2. Withdrawal of funding as the patent application for using glucagon to enhance subcutaneous insulin absorption was not approved. | Phase 1 / Phase 2 | St. Olavs Hospital |
| Novel Approach to Conduction System Pacing With Use of Ultrasound Ultrasound guidance, Fluoroscopy guided | Active not recruiting → Recruiting | Not applicable | Habib Khan |
| Beta-1 Adrenergic Inhibition to Reduce Cardiac Injury and Inflammation After Subarachnoid Hemorrhage (BADCATS) Metoprolol, Placebo | Recruiting → Active not recruiting | Phase 4 | Madeleine Puissant |
| Neoadjuvant Ipilimumab/Nivolumab for Patients With Recurrent, High Risk, Resectable Melanoma Ipilimumab, Nivolumab | Recruiting → Withdrawn Low Accrual | Phase 2 | University of Utah |
| A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD WVE-006 | Active not recruiting → Recruiting | Phase 1 / Phase 2 | Wave Life Sciences USA, Inc. |
| Axelopran and Nivolumab in PD-1-Refractory Metastatic Melanoma Axelopran, Nivolumab | Not yet recruiting → Recruiting | Phase 1 / Phase 2 | John Kirkwood |
| Evaluation of Aqueous Humor DEL-1 and IL-17 Levels in Diabetic Cataract Patients Observational Study Procedure | Recruiting → Completed | Uşak University | |
| Advancing Strategies to Optimize the PerIopeRativE Management of PostOperative Nausea and Vomiting (ASPIRE-PONV) Trial AW-D Clinical Decision Support Tool | Recruiting → Active not recruiting | Not applicable | Vanderbilt University Medical Center |
| Evaluating the Impact of Social Music Music | Recruiting → Completed | Not applicable | Yale University |
| Telerehabilitation in People With Parkinson's Disease VRRS Tablet (Khymeia s.r.l., Noventa Padovana, Italy), Conventional rehabilitation | Recruiting → Completed | Not applicable | IRCCS San Raffaele Roma |
| Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of BGM1812 Injection Following Single and Multiple Subcutaneous Administration in Normal to Overweight or Obese But Otherwise Healthy Men and Women BGM1812, Placebo | Completed → Active not recruiting | Phase 1 | BrightGene Bio-Medical Technology Co., Ltd. |
| Integrated Clinical Decision Support for Empiric Antibiotic Selection in Sepsis Clinical Decision Support Algorithm for Empiric Antibiotics in Sepsis | Recruiting → Terminated Funding. | Not applicable | Ottawa Hospital Research Institute |
| Impact of a Multiplex Respiratory PCR Test on Outcomes for Patients Presenting With Respiratory Illness in the Urgent Care Setting: A Hybrid-Effectiveness Quasi-Experimental Trial SPOTFIRE R/ST Diagnostic Test | Recruiting → Completed | Not applicable | BioMérieux |
| A Phase 3 Clinical Study of QL2106 Injection QL2106 injection, Tremfya® | Recruiting → Active not recruiting | Phase 3 | Qilu Pharmaceutical Co., Ltd. |
| A Study With CIT-013 in HS Patients CIT-013 high dose, CIT-013 medium dose, Placebo | Recruiting → Active not recruiting | Phase 2 | Citryll BV |
| A Study of Caregiver Connections Via Technology in Dementia Algorithm, Random Match | Active not recruiting → Completed | Not applicable | Mayo Clinic |
| A Study of SPY072 in Adults With Moderate to Severe Hidradenitis Suppurativa (The SKYLIGHT Trial) SPY072, Placebo, bimekizumab | Not yet recruiting → Recruiting | Phase 2 | Spyre Therapeutics, Inc. |
| Oral Switch in Pediatric Bloodstream Infections Oral antibiotic therapy, Standard IV antibiotic therapy | Not yet recruiting → Recruiting | Phase 4 | Ulrikka Nygaard |
| A Multi-centre Trial to Assess the Efficacy and Safety of the Omnipod 5 System in People With Type 2 Diabetes Undergoing Haemodialysis Omnipod 5, Insulin injections | Not yet recruiting → Recruiting | Not applicable | Imperial College London |
| Optimizing Outcomes for Young Autistic Children Social Communication, Disruptive Behavior, Social Communication + Reduce Frequency | Recruiting → Active not recruiting | Phase 2 | Northwestern University |
| Lipopolysaccharide Adsorption (Efferon LPS NEO) in Children With Thermal Burns Efferon LPS NEO | Recruiting → Withdrawn No patients meeting the study eligibility criteria were identified | Efferon JSC | |
| Physical Activity Intervention Among Older Women With Gynecologic Cancers (Fit4Treatment) Fit4Treatment | Recruiting → Active not recruiting | Not applicable | Northwestern University |
| Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus IV Infused Pembrolizumab Plus Chemotherapy in Adult Participants With Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC) Livmoniplimab, Budigalimab, Pembrolizumab | Recruiting → Active not recruiting | Phase 2 / Phase 3 | AbbVie |
| Developing a Decision Tool for Diverticulitis in the Emergency Department Using Ultrasound Ultrasound | Unknown → Completed | Northwell Health | |
| Inhaled Insulin vs Rapid-acting Injections for Post-meal Glucose Control in Women With Gestational Diabetes Inhaled Technosphere Insulin | Recruiting → Completed | Phase 2 / Phase 3 | Jaeb Center for Health Research |
| Observatory of Prolymphocytic Leukemia T Molecular caracterization | Recruiting → Active not recruiting | French Innovative Leukemia Organisation | |
| Cooling of the Knee After Total Knee Arthroplasty Cool Down Liquid with Bandage ( CoolDown, CH), Ice package cooling system, Standard Postoperative Protocol Without Cooling | Not yet recruiting → Completed | Not applicable | Clinical Center of Vojvodina |
| Evaluation of Pulpotomy, Partial Pulpotomy, and Direct Pulp Capping Using Mineral Trioxide Aggregate. pulp capping with MTA | Active not recruiting → Completed | Not applicable | Delta University for Science and Technology |
| Pediatric Orotracheal Suctioning Training Using a Benner Model-Based Augmented Reality Application Benner Model-Based Augmented Reality Training, Conventional Mannequin-Based Training | Unknown → Completed | Not applicable | Medipol University |
| Extended Access Program With Lorcaserin For The Treatment of Dravet Syndrome and Other Refractory Epilepsies Lorcaserin | Available → No longer available | Eisai Inc. | |
| EMPOWER 3: Improving Palliative Care Health Literacy and Utilization Multimedia Psychoeducational Intervention, Enhanced Usual Care | Active not recruiting → Completed | Not applicable | Tulane University |
| Telehealth Interventions for Cardiac Surgery Telehealth Monitoring | Active not recruiting → Completed | Not applicable | Liverpool Heart and Chest Hospital NHS Foundation Trust |
| Impact of Early ADL Participation on Outcomes Post DRF ADL/Cast Care instruction, Cast Care Instruction | Recruiting → Completed | Phase 1 | George Washington University |
| Driving After Shoulder Surgery Driving simulator | Unknown → Recruiting | Not applicable | The Hawkins Foundation |
| Hedonic and Homeostatic Appetite Control in Obesity and Type 2 Diabetes in the Context of Meal and Exercise Timing Exercise, Control | Active not recruiting → Completed | Not applicable | Steno Diabetes Center Copenhagen |
| Nivolumab and BMS986205 in Treating Patients With Stage II-IV Squamous Cell Cancer of the Head and Neck Nivolumab, IDO1 Inhibitor BMS-986205, Therapeutic Conventional Surgery | Active not recruiting → Terminated Study was terminated early due to toxicity concerns by the Sponsor. | Phase 2 | Thomas Jefferson University |
| Fibrinogen in Liver Transplant Intercept Fibrinogen Complex (IFC), Cryoprecipitate Antihemophilic Factor (AHF) | Not yet recruiting → Recruiting | Phase 4 | Trauma Hemostatis and Oxygenation Research (THOR) Network |
| Pancoronavirus Vaccine Study in Healthy Adults CoV-RBD-scNP-001 and 3M-052-AF | Active not recruiting → Terminated Adjuvant stability not extended | Phase 1 | Duke University |
| Sleeve Gastrectomy With Jejuno-ileal Bypass Versus Single Anastomosis Sleeve Jejunal Bypass SGJIB, SAS-JB | Unknown → Completed | Not applicable | Minia University |
| Study of HS-20093 Versus Gemcitabine in Combination With Docetaxel in Treatment of Osteosarcoma After Previous Second-line Treatment Failure HS-20093, Gemcitabine combined with docetaxel | Active not recruiting → Completed | Phase 3 | Hansoh BioMedical R&D Company |
| A Phase II Clinical Study of SHR-7787 Injection Combined With SHR-1316 Injection in Patients With LS-SCLC SHR-7787 Injection, SHR-1316 | Not yet recruiting → Recruiting | Phase 2 | Shanghai Hengrui Pharmaceutical Co., Ltd. |
| Comparative Efficacy of Organizational Skills Training (OST) and Mindfulness-Based Intervention (MBI) Mindfulness-Based Intervention, Organizational Skills Training | Recruiting → Completed | Not applicable | Duke University |
| ADP-A2M4CD8 Monotherapy and in Combination With Nivolumab in HLA-A2+ Subjects With MAGE-A4 Positive Ovarian Cancer (SURPASS-3) Autologous genetically modified ADP-A2M4CD8 cells, Autologous genetically modified ADP-A2M4CD8 cells in combination with Nivolumab | Active not recruiting → Terminated Enrollment was halted following withdrawal of the U.S. IND. Previously enrolled participants completed treatment and follow-up, after which the study was closed. | Phase 2 | USWM CT, LLC |
| Study to Explore the Safety, Tolerability, and Pharmacokinetics of AMG 305 in Subjects With Advanced Solid Tumors AMG 305 | Completed → Terminated Sponsor decision | Phase 1 | Amgen |
| Study to Provide Continued Access to Treatment for Patients Completing a Previous Trial With Efanesoctocog Alfa Efanesoctocog alfa | Recruiting → Active not recruiting | Phase 3 | Swedish Orphan Biovitrum |
| Feasibility Study Comparing One vs Two Probes for TA Among Cervical Cancer Screen Positive WLWH in C1001P-CS5 Rwanda Thermal ablation (TA) with 1 probe, Thermal ablation (TA) with 2 probes | Not yet recruiting → Recruiting | Not applicable | Fred Hutchinson Cancer Center |
| The Effects of Footplate Stiffness on Foot Loading Within Carbon Fiber Custom Dynamic Orthoses Carbon Fiber Custom Dynamic Orthosis, Carbon Fiber Footplate | Recruiting → Completed | Not applicable | Jason Wilken |
| Multi-site Trial of a Brief Behavioral Intervention for Dyspnea in Patients With Advanced Lung Cancer Dyspnea Intervention, Enhanced Usual Care | Not yet recruiting → Recruiting | Not applicable | Massachusetts General Hospital |
| Prospective Human Study Evaluating Changes in Markers of Detoxification, Overall Physical and Mental Health, and Fatigue Following Supplementation With CellCore Protocols CellCore Foundational Protocol, CellCore - BioToxin Binder & Drainage Activator | Not yet recruiting → Recruiting | Not applicable | OvationLab |
| A Study to Test How Much BI 3034701 Gets Into the Blood in Healthy People When Given in Two Different Ways BI3034701 formulation II, BI3034701 formulation C1 | Not yet recruiting → Recruiting | Phase 1 | Boehringer Ingelheim |
| Walking Rehabilitation After Spinal Cord Injury: Locomotor Training Using Adaptive Robotics Hybrid Assistive Limb (HAL) | Unknown → Active not recruiting | Not applicable | Brooks Rehabilitation |
| Lipopolysaccharide Adsorption (Efferon LPS) in Patients With Thermal Burns Efferon LPS | Recruiting → Withdrawn No patients meeting the study eligibility criteria were identified | Efferon JSC | |
| A Randomized, Placebo Controlled Trial of L Max in Healthy Adult Athletes L Max, Placebo | Active not recruiting → Completed | Not applicable | Climatic, Inc. |
| Functional Near-infrared Spectroscopy in Unconscious Patients single-center prospective pilot study | Recruiting → Completed | Not applicable | Emanuela Keller |
| GUT-FEELINGS: Using Citizen Science for Large-Scale Prebiotic Clinical Trials for Mental Wellness in Adults Active Gut Feeling Product 1, Active Gut Feeling Product 2, Placebo Gut Feeling Control Product | Not yet recruiting → Recruiting | Not applicable | Holobiome, Inc. |
| A Hybrid Effectiveness/Implementation Trial of the International Guide for Monitoring Child Development International Guide for Monitoring Child Development | Active not recruiting → Completed | Not applicable | Brigham and Women's Hospital |
| Activity for Diabetic Polyneuropathy Standard Care Counseling, Supervised Exercise and Counseling | Unknown → Completed | Not applicable | University of Utah |
| Real-world Evaluation of the Implementation of LC-OCT in Daily Clinical Practice | Not yet recruiting → Recruiting | Maastricht University Medical Center | |
| ANRS0268s POSTCOVIET | Unknown → Completed | ANRS, Emerging Infectious Diseases | |
| Open Label Safety Study of Tradipitant in Idiopathic and Diabetic Gastroparesis Tradipitant | Recruiting → Completed | Phase 3 | Vanda Pharmaceuticals |
| Gait Training Through a Novel Over-ground Wearable Robotic System in People With Pyramidal Hemisyndromes Indego Therapy | Unknown → Active not recruiting | Not applicable | IRCCS San Raffaele Roma |
| Reducing Chronic Pain Following Cesarean Delivery Empowered Relief | Not yet recruiting → Recruiting | Not applicable | Stanford University |
| Evaluating Social Perception Dynamics Social perception tasks | Enrolling by invitation → Completed | Not applicable | Yale University |
| Sub-symptom Threshold Aerobic Exercise After Mild Traumatic Brain Injury Sub-symptom threshold aerobic exercise | Active not recruiting → Completed | Not applicable | Oslo University Hospital |
| Bundle Branch Pacing to Preserve Ejection Fraction in Atrial Fibrillation Trial LBBA pacing, Conventional pacing | Not yet recruiting → Recruiting | Not applicable | Poitiers University Hospital |
| Mindfulness-based Neurofeedback to Augment Psychotherapy for Adults With Borderline Personality Disorder mindfulness-based Neurofeedback, control Neurofeedback | Recruiting → Active not recruiting | Phase 2 | Yale University |
| Lacticaseibacillus Rhamnosus LRa05 for Alleviating Allergic Rhinitis probiotic product, Maltodextrin | Not yet recruiting → Completed | Not applicable | Wecare Probiotics Co., Ltd. |
| Research on the Use of Probiotics in the Prevention and Treatment of Inflammatory Bowel Disease Probiotic | Recruiting → Completed | Not applicable | Wecare Probiotics Co., Ltd. |
| A Study of Botensilimab (AGEN1181) for the Treatment of Advanced Melanoma Botensilimab, Balstilimab | Active not recruiting → Terminated Sponsor decision | Phase 2 | Agenus Inc. |
| Intranasal Insulin and Olanzapine Study in Healthy Volunteers OLANZapine 2.5 MG, Placebo, Insulin Lispro 100 UNT/ML | Active not recruiting → Completed | Phase 1 | Centre for Addiction and Mental Health |
| A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202) cyclosporine, Matched Unrelated Donor Hematopoetic Stem Cell Transplant, horse anti-thymocyte globulin (ATG) | Active not recruiting → Terminated Funding terminated | Phase 3 | Boston Children's Hospital |
| 24VA021; VATCH Trametinib for Ras/MAPK Pathway VAs Trametinib | Active not recruiting → Recruiting | Phase 2 | Children's Hospital of Philadelphia |
| Ketamine Biomarker Validation Ketamine (0.25 mg/kg), Ketamine (0.5 mg/kg), Ketamine (0.75 mg/kg) | Not yet recruiting → Withdrawn Funding was not provided | Phase 1 | Soterix Medical |
| Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy Anticoagulant Therapy, Catheter-Directed Therapy | Recruiting → Active not recruiting | Phase 3 | NYU Langone Health |
| Evaluating Simplified Layered Consent for Clinical Trials Simplified layered consent form, Full-length consent form | Recruiting → Completed | Not applicable | Sunnybrook Health Sciences Centre |
| Targeting of Preventive Treatment for Adolescents at Risk of Oral Diseases Lumoral Treatment, Standard, personalized oral health care | Recruiting → Completed | Not applicable | Wellbeing Services County of Pirkanmaa |
| MRG003 Induction and Capecitabine Maintenance With PD-1 in Locally Recurrent NPC MRG003, Tislelizumab, Capecitabine | Not yet recruiting → Recruiting | Phase 2 | Fujian Cancer Hospital |
| The Norwegian Trial of Physical Exercise After Myocardial Infarction Physical exercise, Standard care, Observation group | Enrolling by invitation → Active not recruiting | Not applicable | Norwegian University of Science and Technology |
| Study of the Efficacy of Dietary Supplementation in Targeting Sleep Quality (NutriSom-01B) 21 days of intervention with Placebo Product (PP), 21 days of intervention with Active Control (AC), 21 days of intervention with Test Product (TP) | Not yet recruiting → Completed | Not applicable | Institute of Nutrition, Slovenia (Nutris) |
| Ultrasound for Diagnosing Costochondral Joint Separation Ultrasound (USG) | Not yet recruiting → Completed | Not applicable | Caner İşevi, MD |
| Lupus Nephritis Care Pathway Lupus Nephritis (LN) Care Pathway | Not yet recruiting → Recruiting | Not applicable | Duke University |
| Educational Eczema Video Intervention in-clinic video intervention, at home video intervention | Not yet recruiting → Withdrawn never obtained funding | Not applicable | Boston Children's Hospital |
| A Study to Evaluate the Safety,Pharmacokinetics,Pharmacodynamics,and Efficacy of TJ037130 in Adult Participants With Advanced Solid Tumors TJ037130 | Not yet recruiting → Recruiting | Phase 1 | TJ Biopharma Co., Ltd. |
| ACB With S-ESPB Versus ACB With iPACK for Knee Arthroplasty Adductor Canal Block, Sacral Erector Spinae Plane Block, iPACK Block | Recruiting → Completed | Not applicable | Poznan University of Medical Sciences |
| SHAPE Test for Preoperative Risk Stratification Shape II | Recruiting → Active not recruiting | Yale University | |
| Effects of the 4-7-8 Breathing Technique on Postoperative Pain Scores, Anxiety, and Sleep Quality in Patients 4-7-8 Breathing Technique | Not yet recruiting → Completed | Not applicable | Konya Beyhekim Training and Research Hospital |
| Pilot Investigation to Evaluate FlowOx2.0™ for Experimental Treatment of Spasticity FlowOx™ | Unknown → Completed | Not applicable | Otivio AS |
| Effects of 8 Weeks of Turmeric Ingestion on Physiology and Wellbeing in Healthy Older Adults Raw turmeric shots, Placebo | Recruiting → Completed | Not applicable | Nottingham Trent University |
| Feasibility Study Comparing One vs Two Probes for Thermal Ablation Among Cervical Cancer Screen Positive Women Living With HIV in C1001P-CS7 Zimbabwe Thermal ablation (TA) with 1 probe, Thermal ablation (TA) with 2 probes | Not yet recruiting → Recruiting | Not applicable | Fred Hutchinson Cancer Center |
| Immunotherapy and Nodal-Sparing Irradiation for T-Cell Induction and Unmasking of Tumor Antigenicity in the Microenvironment for Head and Neck Cancer Pembrolizumab, Radiotherapy, ENI | Not yet recruiting → Recruiting | Phase 2 | Medical College of Wisconsin |
| Slow Wave Sleep as a Biomarker of Rehabilitation-induced Cognitive Improvement in PD Progressive Resistance Training (PRT), Delayed Exercise Training (DE), Endurance Training (ET) | Unknown → Active not recruiting | Not applicable | University of Colorado, Denver |
| Prophylactic Transfusion In Pregnant in Women With Sickle Cell Disease Prophylactic Transfusion Intervention group: Transfusion, Control group | Recruiting → Withdrawn The study was withdrawn due to no enrollment | Phase 4 | Emory University |
| An Observational Study to Learn How Mirena and Other Progestogen Treatments Are Used for Endometrial Protection in Women 40+ With a Uterus in the United States Receiving Estrogen Therapy, and Their Respective Health Outcomes Estrogen therapy, Mirena levonorgestrel-releasing intrauterine system, Other progestogen therapy | Not yet recruiting → Active not recruiting | Bayer | |
| A Study of IBI3046 in Participants With Overweight or Obesity IBI3046, placebo | Not yet recruiting → Recruiting | Phase 1 | Innovent Biologics (Suzhou) Co. Ltd. |
| Performance and Long-term Safety of FlowOx2.0™ in Patients With Multiple Sclerosis - Impact on Spasticity and Pain FlowOx 2.0, FlowOx2.0 (Sham) | Unknown → Completed | Not applicable | Otivio AS |
| AVEIR DR Coverage With Evidence Development (CED) Study Aveir DR Leadless Pacemaker System, Dual Chamber Transvenous Pacemaker | Recruiting → Active not recruiting | Abbott Medical Devices | |
| Super Chef - an Online Program Promoting the Mediterranean Dietary Pattern to Lower Income Families Super Chef: Family Fun in the Kitchen! | Active not recruiting → Completed | Not applicable | Baylor College of Medicine |
| A Preliminary Study on the Efficacy of Danggui Shaoyao San and Cuscuta Chinensis in Patients With Primary Dysmenorrhea Danggui Shaoyao San (DSS), Cuscuta Chinensis (Tu Si Zi), Combination Therapy (DSS + Tu Si Zi) | Unknown → Terminated The study was stopped early before reaching the planned enrollment of 200 participants because the allocated research budget was exhausted and additional study medication could not be funded. Enrollment will not resume. | Not applicable | Taichung Tzu Chi Hospital |
| Effectiveness of a Home-Based Exercise Program Supported by Self-Management Education in People With Parkinson Disease Self-Management Education and Home Exercise Program, Parkinson Disease Educational Booklet | Not yet recruiting → Active not recruiting | Not applicable | Istanbul University |
| Personal Health Train for Radiation Oncology in India and The Netherlands | Active not recruiting → Completed | Maastricht Radiation Oncology | |
| Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer Domvanalimab, Zimberelimab, Carboplatin | Active not recruiting → Completed | Phase 2 | Arcus Biosciences, Inc. |
| Nebulized Ketamine Plus Standard Care vs. Standard Care Alone in Moderate to Severe Asthma Exacerbations Nebulized ketamine (0.5 mg/kg in normal saline to a total volume of 5ml) plus standard asthma excaerbationcare, Placebo nebulization (5 mL normal saline) plus standard asthma care | Not yet recruiting → Recruiting | Phase 2 | Oman Medical Speciality Board |
| Continuous Versus Intermittent Enteral Feeding and Gastric Residual Volume in Critically Ill Patients Continuous Enteral Feeding, Intermittent Enteral Feeding | Not yet recruiting → Recruiting | Not applicable | Viet Duc University Hospital |
| Scapular Stabilization Versus Proprioceptive Neuromuscular Facilitation Technique in Scapular Dyskinesis Scapular Stabilization Exercises+ Proprioceptive Neuromuscular Facilitation, Patient engagement through warm-up and Scapular Stabilization exercises | Enrolling by invitation → Active not recruiting | Not applicable | University of Lahore |
| Leniolisib for Immune Dysregulation in PIDs Leniolisib | Active not recruiting → Completed | Phase 2 | Pharming Technologies B.V. |
| Open-label Study of WVE-N531 in Patients With Duchenne Muscular Dystrophy (FORWARD-53) WVE-N531 | Recruiting → Active not recruiting | Phase 1 / Phase 2 | Wave Life Sciences USA, Inc. |
| ADAPT Study: Long-term Safety Study of INZ-701 in Patients With ENPP1 Deficiency and ABCC6 Deficiency INZ-701 | Active not recruiting → Terminated The study was terminated by the sponsor prior to planned completion based on a review of the data across indications and overall program considerations. Study termination was not related to participant safety. | Phase 2 | Inozyme Pharma |
| RESET-COPD Cohort: Real-Time Monitoring and Early Warning in COPD Patients Receiving Home NPPV Not applicable- observational study | Enrolling by invitation → Recruiting | Beijing Chao Yang Hospital | |
| A Phase 1b/2 Multisite Dose-finding and Expansion Study of WTX-330 in Adult Patients With Selected Advanced or Metastatic Solid Tumors or Lymphoma WTX-330 | Active not recruiting → Completed | Phase 1 / Phase 2 | Werewolf Therapeutics, Inc. |
| Piloting a School-Based Distress Tolerance Skills Program for Adolescents Distress Tolerance Skills Training | Active not recruiting → Completed | Not applicable | Oregon Health and Science University |
| Evaluation of a Supervised Clinical Feeding Intervention Supervised feeding intervention, Handout | Not yet recruiting → Withdrawn no funding | Not applicable | Boston Children's Hospital |
| Pediatrics Mobile CT Mobile CT | Recruiting → Completed | Not applicable | Duke University |
| Medication Use and Quality of Life Among Older People Deprescribing intervention | Active not recruiting → Completed | Not applicable | Odense University Hospital |
| 24VA022; VATCH Alpelisib for TIE2/PIK3CA Pathway VAs alpelisib (BYL719) | Active not recruiting → Recruiting | Phase 2 | Children's Hospital of Philadelphia |
| Effects of Cytotoxic Chemotherapy and PARP Inhibition on the Genomic Contexture of Ovarian Cancer | Unknown → Completed | Hellenic Cooperative Oncology Group | |
| Previfenon® as Chemoprophylaxis of COVID-19 in Health Workers Previfenon®, Placebo | Unknown → Withdrawn The protocol was withdrawn because enrollment did not begin. | Phase 2 / Phase 3 | MELISA Institute Genomics & Proteomics Research SpA |
| Bedside Spirometry for Acute Lung Injury Hand-held spirometer, NIV | Not yet recruiting → Recruiting | Not applicable | Centre Hospitalier Departemental Vendee |
| Smart Underwear to Measure Diet-Induced Hydrogen Sulfide Production High Cysteine Diet, Low Cysteine Diet | Recruiting → Completed | Not applicable | University of Colorado, Denver |
| Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer PET-directed Local Therapy using Surgery, PET-directed Local Therapy using Radiation, Salvage Local Therapy for locally recurrent disease | Recruiting → Active not recruiting | Phase 2 / Phase 3 | VA Office of Research and Development |
| Mortality and Muscle Mass Loss in Critically Ill Patients. | Not yet recruiting → Recruiting | Brno University Hospital | |
| Naturally Banded Versus Synthetic Banding of Sleeve Gastrectomy natural band, silicone band | Unknown → Completed | Not applicable | Minia University |
| Light Therapy in End Stage Kidney Disease Bright light, Dim Light | Active not recruiting → Completed | Not applicable | University of Pennsylvania |
| BXCL701 Phase 1 R/R Acute Myeloid Leukemia or Myelodysplastic Syndrome BXCL701 | Recruiting → Active not recruiting | Phase 1 | Eric Stephen Winer, MD |
| Video Education With Result Dependent dIsclosure Video Education, Genetic Counseling | Recruiting → Completed | Not applicable | Dana-Farber Cancer Institute |
| A Study to Evaluate the Cariostatic Efficacy of Nano Silver Fluoride (NSF) vs. Silver Diamine Fluoride (SDF) in Children Nano Silver Fluoride / NSF | Not yet recruiting → Recruiting | Not applicable | A.T. Still University of Health Sciences |
| Ambient AI for Reducing Nursing Staff Documentation Time Artificial Intelligence | Recruiting → Active not recruiting | Not applicable | University of Wisconsin, Madison |
| QLS31905 in Combination With CAPOX Versus Sintilimab in Combination With CAPOX as First-line Treatment in Patients With GC/GEJ QLS31905, Sintilimab, Oxaliplatin | Not yet recruiting → Recruiting | Phase 3 | Qilu Pharmaceutical Co., Ltd. |
| Consumer Health Study Aims to Evaluate the Safety, Tolerability and Impact of ED02 Probiotic Supplement on Gastrointestinal Outcomes Bifidobacterium pseudocatenulatum, Placebo | Active not recruiting → Completed | Not applicable | Synbiotic Health |
| A Study Of Auricular Transcutaneous Vagus Nerve Stimulation In Chronic Dizziness Sham Device, Auricular transcutaneous vagus nerve stimulation | Recruiting → Enrolling by invitation | Not applicable | Mayo Clinic |
| Efficacy of Genicular Block on Total Knee Arthroplasty Surgery Genicular blocks (bupivakain), placebo injection with 0.9% sodium chloride, Paracetamol (acetaminophen)+diclofenac | Not yet recruiting → Completed | Not applicable | Mersin University |
| A Study to Learn How Men With Advanced Prostate Cancer Respond to Treatment With Darolutamide and Hormone Therapy, With or Without Chemotherapy, in Real-world Medical Practice Darolutamide (BAY 1841788), ADT, Docetaxel | Active not recruiting → Recruiting | Bayer | |
| 3rd Generation Resorbable Magnesium Scaffolds vs Biodegradable Polymer Stents in NSTE/ACS Percutaneous coronary intervention | Not yet recruiting → Withdrawn No funding | Not applicable | Konstantinos Toutouzas |
| Software as a Medical Device for the Treatment of Patients With PTSD Software as a Medical Device | Recruiting → Active not recruiting | Phase 2 / Phase 3 | Otsuka Medical Devices Co., Ltd. Japan |
| Melanoma: Genomic Profiles, Molecular Markers and Therapeutic Implications | Unknown → Active not recruiting | Hellenic Cooperative Oncology Group | |
| Trastuzumab Rezetecan and Adebrelimab as Neoadjuvant Therapy for HER2-Positive Muscle-Invasive Bladder Cancer Trastuzumab Rezetecan Combined with Adebelizumab | Not yet recruiting → Active not recruiting | Phase 2 | Harbin Medical University |
| The RIPPLE AT-PLUS Study Catheter ablation of atrial tachycardia: Ripple Mapping guided., Catheter ablation of atrial tachycardia: Conventional mapping guided. | Active not recruiting → Completed | Not applicable | Liverpool Heart and Chest Hospital NHS Foundation Trust |
| CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy for Relapsed/Refractory B Cell Non-Hodgkin Lymphoma (ANTLER) CB-010, Cyclophosphamide, Fludarabine | Unknown → Active not recruiting | Phase 1 | Caribou Biosciences, Inc. |
| Dupilumab De-escalation in Pediatric Atopic Dermatitis Dupilumab - Discontinuation, Dupilumab - Dose Reduction, Dupilumab - Standard Dose | Recruiting → Terminated Poor accrual | Phase 4 | Johns Hopkins University |
| Aveir VR Coverage With Evidence Development Post-Approval Study Aveir VR Leadless Pacemaker System, Single-Chamber Transvenous Pacemaker | Recruiting → Active not recruiting | Abbott Medical Devices | |
| Unmet Needs, Barriers and Facilitators to Vision Services for Children and Adolescents With Special Vision observational study, no intervention | Enrolling by invitation → Completed | National Taiwan University Hospital | |
| Effects of Ankle Evertor Fatigue on Perturbed Gait Muscle fatigue | Recruiting → Completed | University of Ljubljana | |
| Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) Immune Kidney Transplant Study (COVID-19) SARS-CoV-2 vaccine | Unknown → Completed | Oslo University Hospital | |
| Music Mindfulness Study 2a. in person meditation, in person meditation using headphones, virtual meditation | Recruiting → Completed | Not applicable | Yale University |
| A Study With CIT-013 in RA Patients CIT-013 low dose, CIT-013 high dose, Placebo | Recruiting → Completed | Phase 2 | Citryll BV |
| KN035 for dMMR/MSI-H Advanced Solid Tumors KN035 | Recruiting → Active not recruiting | Phase 2 | 3D Medicines (Sichuan) Co., Ltd. |
| Comparison of the Effects of External Oblique Intercostal Plane Block and Subcostal Transversus Plane Block Methods With Ultrasound Guidance on Postoperative Analgesia in Laparoscopic Sleeve Gastrectomy Operations Ultrasound-guided external oblique intercostal plane block, Local anesthetic infiltration, Subcostal Transversus Abdominis Plane Block (s-TAP) | Not yet recruiting → Completed | Not applicable | Sanliurfa Education and Research Hospital |
| A Study to Learn About the Safety of BIIB147 and Its Effects in Adults With Amyotrophic Lateral Sclerosis (ALS) BIIB147, Placebo | Not yet recruiting → Recruiting | Phase 1 / Phase 2 | Biogen |
| CARdiAc Mri and BiOLogical samplEs at the Acute Phase of a Myocardial Infarction (CARAMBOLE) Blood, urinary and feces collection, Cardiac MRI, Quality of life and cognitive status questionnaire | Active not recruiting → Completed | Not applicable | Poitiers University Hospital |
| Effect of Periumbilical Vibration on Pain Perception During Intrauterine Device Insertion: A Randomized Controlled Trial Periumbilical Vibration during Intrauterine Device Placement | Not yet recruiting → Recruiting | Not applicable | Duke University |
| Performance and Long-term Safety of FlowOx2.0™, Multiple Sclerosis, Spasticity and Pain FlowOx 2.0 | Unknown → Completed | Not applicable | Otivio AS |
| Prescribed Knee Brace Treatments for Osteoarthritis of the Knee (Knee OA) This is a non interventional registry | Enrolling by invitation → Recruiting | Össur Iceland ehf | |
| Window Trial of Intratumoral (IT) Neoadjuvant Fluorescently Labelled Nivolumab (nivo800) in Head and Neck Squamous Cell Carcinoma (HNSCC) Nivolumab-IRDye800 | Not yet recruiting → Recruiting | Early Phase 1 | Vanderbilt-Ingram Cancer Center |
| Effects of Ankle Evertor Fatigue on Force Sense and Neuromuscular Activation in Subjects With Chronic Ankle Instability | Recruiting → Completed | University of Ljubljana | |
| Neurophysiological Benefits of Live Music for Early Alzheimer's Patients and Their Caregivers Pre-recorded Music Session, Live Music Session | Active not recruiting → Completed | Not applicable | Yale University |
| A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes Orforglipron, Dulaglutide | Not yet recruiting → Recruiting | Phase 3 | Eli Lilly and Company |
| Basal Cell Carcinoma Chemoprevention Trial 5% Imiquimod cream, Placebo Vehicle Control Cream | Not yet recruiting → Recruiting | Phase 3 | VA Office of Research and Development |
| A Study to Learn About How a New Nurandociguat Tablet is Absorbed and Processed in the Body Compared to an Old Tablet and How Food Affects the Way the New Tablet is Absorbed and Processed in the Body Nurandociguat (BAY3283142) old tablet - SD, Nurandociguat (BAY3283142) new tablet - SD, Nurandociguat (BAY3283142) old tablet | Recruiting → Completed | Phase 1 | Bayer |
| CREDE Study: Intraoperative Crede Manoeuver Compared to Preoperative Prolapse Reduction Stress Test to Predict Postoperative de Novo Stress Urinary Incontinence (PONSUI) at the Time of Pelvic Organ Prolapse (POP) Surgery Intraoperative Crede manoeuver, Preoperative prolapse reduction cough stress test | Unknown → Terminated Prolonged slow recruitment | Not applicable | McGill University Health Centre/Research Institute of the McGill University Health Centre |
| Real World Data Analysis of PARP Inhibitors Use in Patients With Ovarian Cancer PARP inhibitor | Unknown → Completed | Hellenic Cooperative Oncology Group | |
| Finnish Venous Ulcer Study (FINNULCER Study) Endothermal Ablation, Foam Sclerotherapy | Recruiting → Completed | Not applicable | Oulu University Hospital |
| A Phase 1 Relative Bioavailability Study of a VX-581 Tablet Formulation VX-581 | Not yet recruiting → Recruiting | Phase 1 | Vertex Pharmaceuticals Incorporated |
| Hearing Outcomes With the Nucleus® 8 Sound Processor and Nucleus® 7 Sound Processor in Adult Veteran and Non-veteran Cochlear Implant Recipients Nucleus 7 Sound Processor, Nucleus 8 Sound Processor | Not yet recruiting → Completed | Not applicable | Cochlear |
| PET-Based Imaging of Radiolabeled CIT-013 [89Zr]Zr-CIT | Recruiting → Completed | Phase 2 | Citryll BV |
| Cannabis Association With Sleep Study Manipulation of Sleep Duration | Not yet recruiting → Recruiting | Not applicable | Oregon Health and Science University |
| MagnetisMM-3: Study Of Elranatamab (PF-06863135) Monotherapy in Participants With Multiple Myeloma Who Are Refractory to at Least One PI, One IMiD and One Anti-CD38 mAb Elranatamab (PF-06863135) | Active not recruiting → Completed | Phase 2 | Pfizer |
| Photobiomodulation for the Prevention of Radiation Induced Oral Mucositis Photobiomodulation | Unknown → Active not recruiting | Not applicable | Ottawa Hospital Research Institute |
| Immunogenicity and Safety Study of an Investigational Quadrivalent Meningococcal Conjugate Vaccine Administered in Healthy Children and Adolescents in China MenACYW conjugate vaccine, MenACYW135 polysaccharide vaccine, MenAC conjugate vaccine | Active not recruiting → Completed | Phase 3 | Sanofi |
| The Effect of Dexamethasone Administration Route and Local Anesthetic Concentration on Pain, Inflammatory Response, and Neuromonitoring in Children Undergoing Scoliosis Correction perineural Dexamethasone, intravenous Dexamethasone | Recruiting → Completed | Phase 4 | Poznan University of Medical Sciences |
| Body-oriented Psychotherapy for Individuals With a History of Child Maltreatment and Trauma-related Symptoms SE-group, Control | Recruiting → Active not recruiting | Not applicable | Monique Pfaltz |
A trial with several areas is listed under each.