24 completed, 8 withdrawn, 6 terminated, 4 recruiting. 22 Phase 4, 6 Not applicable, 2 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 22 | Completed 13, Terminated 4, Withdrawn 3, Recruiting 2 |
| Not applicable | 6 | Completed 2, Terminated 2, Recruiting 1, Withdrawn 1 |
| Phase 2 | 2 | Completed 2 |
| Phase 3 | 1 | Withdrawn 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Virtual Reality and Standard Care vs. Standard Care Alone for Acute MSK Pain in Geriatric ED Patients Standard of Care Analgesia, Standard of Care Analgesia + Virtual Reality - Acute Musculoskeletal Pain | Not applicable | Recruiting | Antonios Likourezos | 180 | 2024-11-18 | 2026-10-15 |
| A Comparison of Nurtec ODT to Maxalt MLT-ODT in Adult ED Patients With Migraine Headache Rimegepant, Rizatriptan Benzoate - Migraine | Phase 4 | Recruiting | Antonios Likourezos | 80 | 2024-09-01 | 2026-09-24 |
| Nebulized Ketamine to Nebulized Fentanyl for Treating Acute Painful Conditions in the ED Ketamine, Fentanyl - Pain, Acute | Phase 4 | Recruiting | Antonios Likourezos | 150 | 2024-05-01 | 2026-09-15 |
| Single Dose Amikacin for Uncomplicated Cystitis in the ED: A Feasibility Study Amikacin - Urinary Tract Infections | Recruiting | Antonios Likourezos | 75 | 2022-09-21 | 2026-09-11 | |
| The Effect of Pretreatment With Intravenous Lidocaine for Intravenous Contrast: Preservative Free Lidocaine, Saline - Pain | Phase 4 | Terminated | Antonios Likourezos | 3 | 2022-01-03 | 2025-05-18 |
| Bubiket Study: Ultrasound Guided Fascia Iliaca Nerve Block With Bupivacaine and Adjuvant Ketamine vs. Bupivacaine Alone Bupivacaine, Ketamine - Pain, Musculoskeletal | Phase 4 | Withdrawn | Antonios Likourezos | 2022-01-01 | 2021-10-11 | |
| Vital Capacity in Ultrasound Guided Serratus Plane Block in ED Patients With Multiple Rib Fractures Acetaminophen, Bupivacain, Saline - Pain | Phase 4 | Terminated | Antonios Likourezos | 3 | 2021-11-01 | 2024-06-11 |
| PENG vs. FIC Block for Hip Fracture ED Patients Nerve Block using FIC Proceedure, Nerve Block using PENG Proceedure - Pain, Hip Fracture | Not applicable | Completed | Antonios Likourezos | 50 | 2021-10-20 | 2026-09-24 |
| Comparison of Nebulized Ketamine to Intravenous Sub-Dissociative Dose Ketamine for Pain Ketamine via Intravenous, Ketamine via BAN - Pain | Phase 4 | Completed | Antonios Likourezos | 150 | 2021-10-04 | 2024-07-03 |
| Prevention of Post Herpetic Neuralgia by Ultrasound Guided Single Nerve Block in the ED Ultrasound guided nerve block - Pain | Withdrawn | Antonios Likourezos | 2021-10-01 | 2022-06-16 | ||
| A Comparison of Proprietary Formulations of Oral Ketamine + Aspirin and Oral Ketamine Alone for Musculoskeletal Pain Aspirin and Ketamine, Oral Ketamine - Pain | Phase 4 | Completed | Antonios Likourezos | 60 | 2021-04-22 | 2024-07-17 |
| An Efficacy and Safety of Proprietary Formulations of Oral Ketamine + Aspirin in Treatment of Acute Headache aspirin and ketamine, Nurtec (Rimegepant) - Pain | Phase 4 | Completed | Antonios Likourezos | 5 | 2021-04-22 | 2024-01-31 |
| Analgesic Efficacy of Orally Administered VTS-K for Pain Management VTS-K - Pain, Acute | Completed | Antonios Likourezos | 25 | 2021-01-08 | 2022-04-08 | |
| Measuring Intraabdominal Pressure, Lactic Acid, and Urine Output Accuryn Monitoring System - Intra-Abdominal Hypertension, Inguinal Hernia | Completed | Antonios Likourezos | 21 | 2021-01-01 | 2026-04-29 | |
| A Study Comparing Recurrent Use of MSIR, Percocet, and Vicodin at Discharge From the ED Morphine Sulfate Immediate Release, Oxycodone/Acetaminophen, Hydrocodone/Acetaminophen - Pain | Phase 4 | Withdrawn | Antonios Likourezos | 2019-09-01 | 2019-04-23 | |
| Nebulized Sub-dissociative Dose Ketamine at Three Different Dosing Regimens for Treating Acute Pain in the Pediatric ED Nebulized Sub-dissociative Dose Ketamine at either 0.75 mg/kg, Nebulized Sub-dissociative Dose Ketamine at 1 mg/kg, Nebulized Sub-dissociative Dose Ketamine at 1.5 mg/kg. - Pain | Phase 4 | Completed | Antonios Likourezos | 80 | 2019-05-13 | 2025-11-12 |
| Nebulized Sub-dissociative Dose Ketamine for Treating Pain Ketamine 0.75 mg/kg, Ketamine 1.0 mg/kg, Ketamine 1.5 mg/kg - Pain | Phase 4 | Completed | Antonios Likourezos | 120 | 2019-04-16 | 2022-06-15 |
| Pre-hospital Nebulized Ketamine for Pain Nebutlized Ketamine - Pain | Phase 4 | Withdrawn | Antonios Likourezos | 2019-01-15 | 2021-07-30 | |
| Efficacy of Mindfulness as an Intervention in the Pediatric Emergency Department Take-Pause virtual reality, Passive Distraction - Anxiety Fear, Pain | Completed | Antonios Likourezos | 110 | 2018-11-28 | 2019-10-31 | |
| Adult Oral Ibuprofen Study for ED Pain Patients Oral Ibuprofen - Pain, Acute | Phase 4 | Completed | Antonios Likourezos | 225 | 2018-11-01 | 2020-06-04 |
Showing 20 of 42. Sign in to see all of them.
Pain (20) · Agnosia (10) · Acute Pain (4) · Hip Fractures (2) · Arterial Occlusive Diseases (1) · Attention Deficit Disorder with Hyperactivity (1) · Breast Neoplasms (1) · Colonic Neoplasms (1) · Dehydration (1) · Diabetes Insipidus (1) · Headache (1) · Hemorrhage (1) · Hernia, Inguinal (1) · Herpes Zoster (1) · Intra-Abdominal Hypertension (1)
Ketamine (10) · Morphine (5) · Acetaminophen (3) · Aspirin (2) · Bupivacaine (2) · Fentanyl (2) · Ibuprofen (2) · Ketorolac Tromethamine (2) · Sodium Chloride (2) · rimegepant sulfate (2) · Amikacin (1) · Bronchoscopy (1) · Central Nervous System Stimulants (1) · Diltiazem (1) · Ketorolac (1)
United States (41)
Sergey Motov, MD (17) · John Marshall, MD (6) · Christian Fromm, MD (2) · Eitan Dickman, MD (2) · Leily Naraghi, MD (2) · Christine Rizkalla, MD (1) · Danny Sherwinter, MD (1) · Donna Marie Manasseh, MD (1) · Estevan Garcia, MD (1) · Hashibul Hannan, MD (1) · Joseph LoCicero, MD (1) · Juan D Pedraza, MD (1) · Judy Lin, MD (1) · Kathleen Malloy, MD (1) · Lawrence Haines, MD (1)
PMID 21485725, PMID 22494596, PMID 25125317, PMID 26041328, PMID 27362908, PMID 29237632, PMID 29807629, PMID 30770244, PMID 31383385, PMID 33238043, PMID 35624056, PMID 35777275, PMID 37058600, PMID 7026295