150 completed, 28 unknown, 22 terminated, 21 recruiting. 252 Phase 2, 52 Phase 3, 27 Phase 1.
Follow Perceptual Disorders: new trials by email Literature Review of Perceptual Disorders trials Research Report on Perceptual Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dexmedetomidine for Invasive Ventilation In the NEOnate Dexmedetomidine Injectable Solution, Glucose 5% Injectable Solution - Invasive Ventilation, Infant Pain | Phase 2 / Phase 3 | Not yet recruiting | Centre Hospitalier Intercommunal Creteil | 246 | 2027-01-01 | 2026-08-26 |
| Safety of F14 Following Total Knee Replacement F14 (sustained release celecoxib) - Analgesia | Phase 2 / Phase 3 | Suspended | Arthritis Innovation Corporation | 100 | 2027-01-01 | 2026-06-05 |
| A Clinical Trial of MK-6916 in Participants With Pain After Bunion Removal Surgery (MK-6916-007) MK-6916, Hydrocodone/acetaminophen (HB/APAP), MK-6916 Placebo - Pain Management | Phase 2 | Not yet recruiting | Merck Sharp & Dohme LLC | 380 | 2026-11-23 | 2026-11-06 |
| Genistein for the Reduction of Adverse Cardiovascular Events (GRACE) Genistein (Unconjugated Isoflavones 100), Placebo - HIV, Vascular Disease | Phase 1 / Phase 2 | Not yet recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 60 | 2026-09-30 | 2026-08-25 |
| Sub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young Adults Sub-dissociative Ketamine Infusion, Normal Saline Placebo Infusion - Sickle Cell Disease, Vaso-Occlusive Pain Episode in Sickle Cell Disease | Phase 2 | Recruiting | Mohsen Saidinejad | 120 | 2026-09-10 | 2026-09-02 |
| Fentanyl Intranasal for Retinopathy of Prematurity Screening in Preterm Infants Fentanyl Citrate (Intranasal), Normal Saline (Placebo, Intranasal) - Neonatal Pain, Retinopathy of Prematurity (ROP) | Phase 1 / Phase 2 | Not yet recruiting | Marsha Campbell-Yeo | 58 | 2026-09-09 | 2026-06-30 |
| Efficacy and Safety of Anrikefon Injection for the Treatment of Postoperative Pain in Patients Undergoing Laparoscopic Hepatectomy Anrikefon Injection, Flurbiprofen - Pain Management | Phase 2 | Not yet recruiting | Tianjin Medical University Cancer Institute and Hospital | 108 | 2026-09-01 | 2026-09-17 |
| Effect of Opioid-Sparing Anesthesia on Postoperative Opioid Consumption and Pain in Elderly Patients Undergoing Spine Surgery Opioid-Sparing Protocol, Routine anesthesia protocol - Opoid Managment, Pain Management | Phase 2 | Not yet recruiting | Massachusetts General Hospital | 120 | 2026-09-01 | 2026-09-08 |
| The Use of Photobiomodulation for Pain and Healing in Cesarean Section Photobiomodulation (PBM), Placebo PBM, Standard Hospital Treatment - Post Partum, Cesarean Birth | Phase 2 | Not yet recruiting | University of Nove de Julho | 30 | 2026-09-01 | 2026-09-08 |
| Efficacy and Safety of Canadá Association in the Treatment of Chronic Pain Canadá, Canadá placebo, Dipyrone - Pain, Chronic | Phase 2 | Withdrawn | EMS | 2026-09-01 | 2023-09-08 | |
| Paracervical Block With Combined Ketorolac and Lidocaine for Osmotic Dilator Placement Ketorolac, oral ibuprofen, Placebo - Pain Management, Abortion | Phase 2 | Recruiting | Rush University Medical Center | 76 | 2026-06-29 | 2026-07-06 |
| Pilot Randomized Control Trial Comparing Oral Ketamine and Oral Oxycodone for Pain Control in Emergency Department Patients oral ketamine, oxycodone - Pain Management | Phase 2 / Phase 3 | Not yet recruiting | Albany Medical College | 60 | 2026-06-24 | 2026-06-26 |
| Phase II, Randomized, Double-blind, Placebo-controlled Clinical Trial to Evaluate the Efficacy and Safety of Omega-3 Fatty Acids as an Adjunct to Morphine in Acute Postoperative Pain Omega-3 fatty acids + Morphine group, Placebo+ Morphine group - Pain Postoperative, Analgesia | Phase 2 | Not yet recruiting | National University of La Rioja | 40 | 2026-06-15 | 2026-06-18 |
| Buprenorphine for Analgesia in Older Adults With Acute Fractures in the Emergency Department Buprenorphine 0.15 MG, Hydromorphone 0.25 mg IV - Fracture | Phase 1 / Phase 2 | Recruiting | The Cooper Health System | 48 | 2026-05-07 | 2026-06-29 |
| Cannabidiol for the Treatment of Diabetic Peripheral Neuropathy: Pilot Study Cannabidiol (CBD) oral solution, Full-Spectrum CBD hemp extract oral solution, Placebo in MCT oil oral solution - Diabetic Peripheral Neuropathic Pain (DPN), Diabetic Neuropathies | Phase 1 / Phase 2 | Recruiting | Florida A&M University | 20 | 2026-04-02 | 2026-04-29 |
| An Open-Label Study of ML-007C-MA in Adults With Alzheimer's Disease Psychosis ML-007C-MA - Psychosis Associated With Alzheimer's Disease | Phase 2 | Enrolling by invitation | MapLight Therapeutics | 210 | 2026-03-25 | 2026-11-12 |
| Sciatic Nerve Block With ALX006 in Subjects Undergoing Bunionectomy ALX006 (bupivacaine extended-release injection), Bupivacaine Hcl 0.25% Inj, Sciatic Nerve Block - Hallux Valgus, Bunionectomy | Phase 2 | Recruiting | Rebel Medicine Inc | 60 | 2026-03-10 | 2026-05-07 |
| Prospective IR-led Sedation Feasibility ketamine, Fentanyl (IV), Midazolam - Anesthesia, Sedation and Analgesia | Phase 1 / Phase 2 | Recruiting | CAMC Health System | 40 | 2026-03-02 | 2026-03-09 |
| Evaluation of the Efficacy and Onset of Action of a Topical Anesthetic Marker Cutaneous marker (Transcutol P+ 20%, Tetracaine 7%, Lidocaine 23%, and dye q.s.), - Pain Management | Phase 2 | Not yet recruiting | Hexsel Dermatology Clinic | 20 | 2026-03-01 | 2025-12-10 |
| Sufentanil Versus Ketamine Intranasally in the Management of Severe Acute Trauma-related Pain in Children. Intranasal Sufentanil, Intranasal Ketamine (IN) - Traumatology, Wounds and Injury | Phase 2 | Not yet recruiting | Fondation Lenval | 116 | 2026-02-05 | 2026-01-28 |
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Agnosia (223) · Pain (59) · Pain, Postoperative (51) · Hallucinations (20) · Neuralgia (13) · Chronic Pain (12) · Acute Pain (11) · Schizophrenia (11) · Psychotic Disorders (9) · Delusions (8) · Osteoarthritis (7) · Opioid-Related Disorders (6) · Phantom Limb (6) · Bunion (5) · Diabetic Neuropathies (5)
Neurobehavioral Manifestations (252) · Pathological Conditions, Signs and Symptoms (252) · Signs and Symptoms (252) · Neurologic Manifestations (251) · Nervous System Diseases (250) · Pain (70) · Pathologic Processes (69) · Postoperative Complications (56) · Mental Disorders (29) · Musculoskeletal Diseases (24) · Neuromuscular Diseases (21) · Central Nervous System Diseases (18) · Peripheral Nervous System Diseases (17) · Neoplasms (15)
Bupivacaine (21) · Acetaminophen (18) · Dexmedetomidine (14) · Ropivacaine (12) · Fentanyl (11) · Ibuprofen (11) · Saline Solution (11) · Lidocaine (10) · Morphine (10) · Sodium Chloride (9) · Epinephrine (7) · Ketamine (7) · Hydromorphone (6) · Oxycodone (6) · Dexamethasone (5)
Assiut University (10) · Pacira Pharmaceuticals, Inc (7) · Baudax Bio (4) · Heron Therapeutics (4) · ACADIA Pharmaceuticals Inc. (3) · Ain Shams Maternity Hospital (3) · Ain Shams University (3) · Asklepieion Voulas General Hospital (3) · AstraZeneca (3) · Johns Hopkins University (3) · Massachusetts General Hospital (3) · McGill University Health Centre/Research Institute of the McGill University Health Centre (3) · Novartis Pharmaceuticals (3) · University of Chicago (3) · Wake Forest University Health Sciences (3)
United States (112) · Canada (19) · Egypt (17) · France (11) · China (10) · Brazil (8) · Germany (7) · Italy (5) · United Kingdom (5) · Bulgaria (4) · Denmark (4) · Greece (4) · Israel (4) · South Korea (4) · Spain (4)
Claudia Campbell, PhD (3) · James Zacny, Ph.D. (3) · Kay Warnott, RN, ACNP (3) · Biljana Lilja (2) · Christine N. Sang, MD, MPH (2) · David H Chi, MD (2) · Erol Onel, MD (2) · Ilise Lombardo, MD (2) · Joseph H. Atkinson, MD (2) · Na Li, MD (2) · Neil Singla, MD (2) · Philip Wilson, MD (2) · Sergey Motov, MD (2)
PMID 22900785, PMID 11133630, PMID 12298311, PMID 12411815, PMID 12873949, PMID 12934209, PMID 1517644, PMID 15513495, PMID 15919269, PMID 16452738, PMID 16521220, PMID 16651569, PMID 17341537, PMID 17414235, PMID 18042413, PMID 18191686, PMID 18311814, PMID 18388680, PMID 18442107, PMID 18591063, PMID 18648238, PMID 19151049, PMID 19214642, PMID 19520544, PMID 19524477, PMID 19535720, PMID 19740486, PMID 1977542, PMID 20012652, PMID 20962287, PMID 20975464, PMID 21368651, PMID 21562445, PMID 21674151, PMID 21765198, PMID 21921019, PMID 22013534, PMID 22227789, PMID 22955296, PMID 23049275, PMID 23241361, PMID 23485015, PMID 23611363, PMID 2367246, PMID 23934921, PMID 24054878, PMID 24399578, PMID 24550805, PMID 24806873, PMID 25175864
2019 (3), 2025 (3), R01DA008391 (3), 2008 (2), R01NS041503 (2), 2009 (1), K01AT001111 (1), P01NS119159 (1), P30CA012197 (1), P50DA009236 (1), R01AG047146 (1), R01AR045506 (1), R01DA030424 (1), R01DA040644 (1), R01MH073673 (1)