54 completed, 10 not yet recruiting, 10 unknown, 9 recruiting. 100 Phase 1, 27 Phase 2.
Follow Perceptual Disorders: new trials by email Literature Review of Perceptual Disorders trials Research Report on Perceptual Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Psilocybin After Trauma Surgery for Pain Psilocybin (Usona Institute), Postoperative analgesia - Pain Management, Postoperative Pain | Phase 1 | Not yet recruiting | Trent Emerick | 70 | 2027-12-31 | 2026-08-06 |
| Magnesium Sulfate in Pediatric Burn Dressing Changes magnesium sulfate, Normal Saline (0.9% NaCl) - Pediatric Burns | Phase 1 | Not yet recruiting | Hennepin Healthcare Research Institute | 10 | 2027-12-01 | 2026-10-09 |
| Genistein for the Reduction of Adverse Cardiovascular Events (GRACE) Genistein (Unconjugated Isoflavones 100), Placebo - HIV, Vascular Disease | Phase 1 / Phase 2 | Not yet recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 60 | 2026-09-30 | 2026-08-25 |
| Fentanyl Intranasal for Retinopathy of Prematurity Screening in Preterm Infants Fentanyl Citrate (Intranasal), Normal Saline (Placebo, Intranasal) - Neonatal Pain, Retinopathy of Prematurity (ROP) | Phase 1 / Phase 2 | Not yet recruiting | Marsha Campbell-Yeo | 58 | 2026-09-09 | 2026-06-30 |
| Combined Ketorolac and Lidocaine Paracervical Block for Office Hysteroscopy paracervical block, Lidocaine, ketorolac - Abnormal Uterine Bleeding, Analgesia | Phase 1 | Enrolling by invitation | Icahn School of Medicine at Mount Sinai | 60 | 2026-07-01 | 2026-10-22 |
| Buprenorphine for Analgesia in Older Adults With Acute Fractures in the Emergency Department Buprenorphine 0.15 MG, Hydromorphone 0.25 mg IV - Fracture | Phase 1 / Phase 2 | Recruiting | The Cooper Health System | 48 | 2026-05-07 | 2026-06-29 |
| Cannabidiol for the Treatment of Diabetic Peripheral Neuropathy: Pilot Study Cannabidiol (CBD) oral solution, Full-Spectrum CBD hemp extract oral solution, Placebo in MCT oil oral solution - Diabetic Peripheral Neuropathic Pain (DPN), Diabetic Neuropathies | Phase 1 / Phase 2 | Recruiting | Florida A&M University | 20 | 2026-04-02 | 2026-04-29 |
| Prospective IR-led Sedation Feasibility ketamine, Fentanyl (IV), Midazolam - Anesthesia, Sedation and Analgesia | Phase 1 / Phase 2 | Recruiting | CAMC Health System | 40 | 2026-03-02 | 2026-03-09 |
| Children of Age 2-6years Undergoing Elective Surgery Will be Divided Into Two Groups Randomly. This Study Aims to Evaluate if Intranasal Dexmedetomidine is Better Than Intranasal Ketamine in Producing Sedation and Reducing Parent Separation Anxiety Before Surgery. Intranasal dexmedetomidine, Intranasal ketamine - Sedation, Preoperative Anxiety Experienced by the Pediatric Patient | Phase 1 / Phase 2 | Not yet recruiting | Liaquat National Hospital & Medical College | 60 | 2026-01-01 | 2025-09-18 |
| Effectiveness of Bupivacaine, Ketorolac, Ketamine, vs Bupivacaine Alone in Reducing Postoperative Pocket Pain Bupivacaine alone OR Bupivacaine-Ketorolac-Ketamine (BKK) Combination - Pain Management | Phase 1 | Not yet recruiting | Kansas City Heart Rhythm Research Foundation | 200 | 2026-01-01 | 2025-08-28 |
| Comparison Of Clinical Outcomes of Intraperitoneal Bupivacaine Instillation Versus Placebo as Preemptive Analgesia in Patients Undergoing Open Appendectomy Bupivacain, Normal Saline - Appendectomy | Phase 1 | Recruiting | Sardar Umer Rehman | 60 | 2025-12-16 | 2026-02-24 |
| a Comparive Study of Ketamine-Propofol Versus Dexmedetomidine-Propofol Sedation in Pediatric Patients Undergoing Cardiac Catheterization for Device Closure of Simple Left-to-right Shunts Ketamine + propofol, Dexmedetomidine + propofol - Sedation and Analgesia | Phase 1 | Recruiting | Ain Shams University | 124 | 2025-10-22 | 2026-06-25 |
| A Study Comparing LTG-001 SDD Formulation To LTG-001 Crystalline Immediate Release Tablets In Healthy Participants LTG-001 SDD, LTG-001 Formulation A Prototype 1, LTG-001 Formulation B Prototype 2 - Pain Management | Phase 1 | Completed | Latigo Biotherapeutics | 14 | 2025-10-06 | 2026-01-14 |
| Effect of RECK in Posterior Spinal Fusion Ropivacaine, Epinephrine, Clonidine, and Ketorolac Injection Cocktail, Placebo - Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease | Phase 1 / Phase 2 | Withdrawn | University of Maryland, Baltimore | 2025-10-01 | 2025-07-31 | |
| EFFECTS OF A FULL SPECTRUM CANNABIS EXTRACT WITH DIFFERENT DOSES OF CBD AND THC ON THE MODULATION OF FIBROMYALGIA: A PILOT, MULTICENTER, OPEN LABEL CLINICAL TRIAL (FRIDINHA) Cannabis - Fibromyalgia | Phase 1 / Phase 2 | Active not recruiting | Federal University of Latin American Integration | 36 | 2025-09-15 | 2026-03-27 |
| Dexamethasone-Enhanced TAP Block in Lapchole Dexamethasone enhanced TAP Block, Marcaine- 0.25% - Laparoscopic Cholecystectomy | Phase 1 | Active not recruiting | Makassed General Hospital | 100 | 2025-08-19 | 2025-09-19 |
| A Phase 1, MAD Study to Evaluate the Safety, Tolerability and Pharmacokinetics of LY03017 LY03017, LY03017-Placebo - Hallucinations and Delusions Associated With Alzheimer's Disease Psychosis, Hallucinations and Delusions Associated With Parkinson Disease Psychosis | Phase 1 | Not yet recruiting | Luye Pharma Group Ltd. | 40 | 2025-05-01 | 2025-05-20 |
| Analgesic Effect of Bupivacaine Plus Ketamine Versus Bupivacaine Alone in Transversalis Fascia Plane Block Ketamine, Bupivacaine, Bupivacain - Analgesia | Phase 1 | Not yet recruiting | Ain Shams University | 68 | 2025-04-25 | 2025-04-20 |
| Opioid-Free Anesthesia in Colorectal Surgery, 2025 (OFA-CRC-2025) Opioid-Free Anesthesia (OFA), Opioid-Based Anesthesia (OBA) - Pain Management, Colorectal Surgery | Phase 1 / Phase 2 | Active not recruiting | Hospital Universitario La Fe | 200 | 2025-03-15 | 2026-08-18 |
| A Randomized Clinical Trial of the Effectiveness of Acupressure in Relieving Orthodontic Pain Acetaminophen, Acupressure - Orthodontic Pain (D013850), Pain Management (D016146) | Phase 1 | Not yet recruiting | University of Baghdad | 56 | 2025-02-10 | 2025-02-10 |
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Agnosia (86) · Pain (34) · Pain, Postoperative (14) · Acute Pain (7) · Chronic Pain (5) · Hallucinations (4) · Phantom Limb (4) · Neoplasms (3) · Stroke (3) · Diverticular Diseases (2) · Emergencies (2) · Fibromyalgia (2) · Inflammation (2) · Narcotic-Related Disorders (2)
Nervous System Diseases (100) · Neurobehavioral Manifestations (100) · Neurologic Manifestations (100) · Pathological Conditions, Signs and Symptoms (100) · Signs and Symptoms (100) · Pathologic Processes (28) · Pain (20) · Postoperative Complications (18) · Mental Disorders (7) · Urogenital Diseases (6) · Digestive System Diseases (5) · Female Urogenital Diseases and Pregnancy Complications (5) · Musculoskeletal Diseases (5) · Neuromuscular Diseases (5)
Acetaminophen (8) · Bupivacaine (8) · Ketamine (8) · Lidocaine (5) · Saline Solution (5) · Oxycodone (4) · Tramadol (4) · Dexamethasone (3) · Epinephrine (3) · Fentanyl (3) · Magnesium Sulfate (3) · Morphine (3) · Naltrexone (3) · Acupuncture Therapy (2) · Buprenorphine (2)
Ain Shams University (3) · Liaquat National Hospital & Medical College (3) · Pacira Pharmaceuticals, Inc (3) · University Hospital, Clermont-Ferrand (3) · Alza Corporation, DE, USA (2) · David Chi, MD (2) · GlaxoSmithKline (2) · Luye Pharma Group Ltd. (2) · Pfizer (2) · Syntrix Biosystems, Inc. (2) · University of California, Los Angeles (2) · University of Maryland, Baltimore (2) · University of Utah (2) · Ashraf elanzy (1) · AstraZeneca (1)
United States (47) · Canada (7) · Egypt (6) · France (4) · Pakistan (4) · Australia (3) · Denmark (3) · Brazil (2) · China (2) · Sweden (2) · Taiwan (2) · United Kingdom (2) · Croatia (1) · Germany (1) · Iraq (1)
David H Chi, MD (2) · Stuart Kahn, MD (2) · Adolfo M Bronstein, Pr, MD (1) · Ali Asgher, Mbbs, FCPS (1) · Alshaimaa Kamel, M.D (1) · Amy R Deipolyi, M.D., Ph.D. (1) · Bo Fransson (1) · Brian Draganic, B.Med.,B.Med.Sci.(Hons),FRACS (1) · Charles Ascher-Walsh, MD (1) · Christopher Kennard, Pr, MD (1) · Colleen Loo, MBBS, FRANZCP. MD (1)
PMID 31005596, PMID 17270055, PMID 17270058, PMID 18311814, PMID 22717418, PMID 22955296, PMID 23241361, PMID 23415783, PMID 23458225, PMID 23936895, PMID 24666686, PMID 24954166, PMID 25139724, PMID 25693889, PMID 25735992, PMID 29570501, PMID 34196963, PMID 35622535, PMID 36600856, PMID 37083674, PMID 38782390, PMID 39411383, PMID 39709396, PMID 40045174, PMID 40396501, PMID 40615143, PMID 42370792, PMID 42458331
2016 (2), K01AT001111 (1), P2CHD086844 (1), R01AR045506 (1), R01AT010762 (1), R44DA027304 (1), U10HD045986 (1)