1475 completed, 333 recruiting, 211 terminated, 183 withdrawn. 1190 Not applicable, 394 Phase 2, 249 Phase 1, 131 Phase 3, 131 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Tracheostomy Robotics and Cutting-edge Health Education for Airway Safety NextGen automated tracheostomy suctioning device, NextGen mixed-reality tracheostomy tube change system, NextGen Tracheostomy Toolkit - Tracheostomy | Not applicable | Not yet recruiting | Johns Hopkins University | 632 | 2027-10-01 | 2024-02-01 |
| Behavioral Pharmacology of THC and Beta-Myrcene Placebo, THC, Beta-Myrcene - Cannabis Use | Phase 1 | Not yet recruiting | Johns Hopkins University | 32 | 2027-07-01 | 2026-07-31 |
| Inpatient Buprenorphine Induction With Psilocybin for Opioid Use Disorder Psilocybin - Opioid Use Disorder | Phase 2 | Withdrawn | Johns Hopkins University | 2027-04-01 | 2026-02-23 | |
| The Impact of Dose on the Impairing, Intoxicating, and Abuse-Related Effects of Psilocybin 0mg Psilocybin Capsule + 0.00% BAC Alcoholic Drink, 1mg Psilocybin Capsule + 0.00% BAC Alcoholic Drink, 5mg Psilocybin Capsule + 0.00% BAC Alcoholic Drink - Psilocybin Intoxication | Phase 1 | Not yet recruiting | Johns Hopkins University | 80 | 2027-03-01 | 2026-10-16 |
| Study to Examine the Effect of Silicone Mouth Tape on Snoring and Mild Sleep Apnea. Mouth Tape - Mild Obstructive Sleep Apnea, Snoring | Phase 2 | Recruiting | Johns Hopkins University | 100 | 2027-03-01 | 2026-06-23 |
| Effects of Cannabidiol (CBD) on a Fixed Dose of Delta-9-tetrahydrocannabinol (THC) 0mg THC + 0mg CBD Brownie, 10mg THC + 0mg CBD Brownie, 10mg THC + 10mg CBD Brownie - Cannabis Intoxication | Phase 1 | Not yet recruiting | Johns Hopkins University | 70 | 2027-02-01 | 2026-10-15 |
| Project HOPE (Hypertension Outreach Through Partnership and Engagement) Project HOPE Intervention - Hypertension (HTN) | Not yet recruiting | Johns Hopkins University | 150 | 2027-02-01 | 2026-09-08 | |
| Study of Bedroom Environment Sleep Intervention at Home for Older Adults Living Alone With Memory Concerns Bedroom Environment Tailoring, Sleep Health Education - Subjective Cognitive Decline (SCD), Mild Cognitive Impairment (MCI) | Not applicable | Not yet recruiting | Johns Hopkins University | 40 | 2027-02-01 | 2026-10-09 |
| Digital Health Technologies for Progressive Supranuclear Palsy and Dementia With Lewy Bodies Progressive Supranuclear Palsy(PSP), Dementia With Lewy Bodies (DLB) | Not yet recruiting | BioSensics | 60 | 2027-01-15 | 2026-10-13 | |
| Relationship Between Anesthetic Regimen and Bone Cement Implantation Syndrome (BCIS) Administration of general anaesthesia, Neuraxial Analgesia - Bone Cement Implantation Syndrome | Not applicable | Enrolling by invitation | Johns Hopkins University | 24 | 2027-01-10 | 2026-07-21 |
| SniffTrain: Effectiveness of Sniff Training in the Treatment of Post-Viral Anosmia Sniff Training Kits - Post-viral Anosmia, Anosmia | Not applicable | Not yet recruiting | University of Virginia | 204 | 2027-01-05 | 2026-10-05 |
| Testing Heart Failure Resilience Intervention for Caregivers (HEROIC) in Advanced Heart Failure HEROIC program, Active Comparator Control 1 - Heart Failure, Caregiver | Phase 2 | Not yet recruiting | Johns Hopkins University | 500 | 2027-01-04 | 2026-09-04 |
| Accelerated Flap Coverage Versus Standard Timing in the Treatment of Severe Lower Extremity Musculoskeletal Injuries Accelerated Flap Coverage Surgery, Standard of Care Flap Timing - Open Tibia Fracture, Open Dislocation of Ankle | Not applicable | Not yet recruiting | Johns Hopkins University | 356 | 2027-01-01 | 2026-09-18 |
| Voice Quality Analysis of Patients With Laryngotracheal Stenosis Voice Biomarker Screening Too - Idiopathic Subglottic Tracheal Stenosis | Not yet recruiting | Johns Hopkins University | 100 | 2027-01-01 | 2026-07-13 | |
| Assessing the Efficacy of Repeat, Monthly Treatments of Alexandrite Laser for NF1-associated Cutaneous Neurofibromas (cNFs) GentleMax Pro (with skin cooling), GentleMax Pro (without skin cooling) - Neurofibromatosis 1 (NF1), Neurofibromatosis Type I | Not applicable | Suspended | Massachusetts General Hospital | 10 | 2027-01-01 | 2026-06-04 |
| The Application of Lifestyle Enhancing Validated Integrative Therapies for Everyday Pain in Cirrhosis High-touch self-management program, Low-touch self-management program - Cirrhoses, Liver | Not applicable | Not yet recruiting | University of Pennsylvania | 625 | 2027-01-01 | 2026-10-02 |
| Daridorexant for Alcohol Use Disorder Daridorexant 50 mg, Placebo - Alcohol Use Disorder | Phase 2 | Not yet recruiting | Johns Hopkins University | 150 | 2027-01-01 | 2026-04-20 |
| Brain Imaging of DSP-2342 DSP-2342 - SCHIZOPHRENIA 1 (Disorder) | Phase 2 | Not yet recruiting | Johns Hopkins University | 20 | 2027-01-01 | 2026-09-30 |
| Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT) INTENT Neural Interface System - Tetraplegia/Tetraparesis, Amyotrophic Lateral Sclerosis (ALS) | Not applicable | Recruiting | Johns Hopkins University | 5 | 2027-01-01 | 2026-10-09 |
| Racism-related Stress and Objective Short-sleep as Moderators of Treatment Effect in Cognitive Behavioral Therapy for Insomnia Cognitive Behavioral Therapy for Insomnia (CBTi) - Insomnia, Stress | Not applicable | Not yet recruiting | Johns Hopkins University | 100 | 2027-01-01 | 2026-09-10 |
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Hypertension (64) · Obesity (64) · Acquired Immunodeficiency Syndrome (63) · Depression (53) · HIV Infections (53) · Cognitive Dysfunction (51) · Substance-Related Disorders (51) · Opioid-Related Disorders (49) · Alzheimer Disease (45) · Dementia (41) · Anxiety Disorders (39) · Breast Neoplasms (39) · Diabetes Mellitus (39) · Stroke (39) · COVID-19 (36)
Psilocybin (29) · Standard of Care (24) · Dronabinol (20) · Saline Solution (20) · Sodium Chloride (18) · Cognitive Behavioral Therapy (16) · Methods (16) · Transcranial Direct Current Stimulation (16) · nabiximols (16) · Buprenorphine (15) · Sugars (14) · Surveys and Questionnaires (14) · Therapeutics (13) · Isoniazid (12) · Azithromycin (11)
United States (2140) · Canada (54) · South Africa (36) · India (33) · Uganda (23) · United Kingdom (22) · Bangladesh (14) · Brazil (14) · Germany (14) · Peru (14) · Australia (12) · China (12) · Tanzania (11) · Zambia (11) · Malawi (10)
Madhav Thambisetty, MD, PhD (14) · Ryan Vandrey, PhD (13) · Steven P Cohen, MD (13) · Kenneth Silverman, Ph.D. (11) · Christine Durand, MD (9) · Eric H Kossoff, MD (8) · Jonathan Jun, MD (8) · Kyrana Tsapkini, PhD (8) · Robert Wood, MD (8) · Tory Spindle, PhD (8) · Alexander Pantelyat, MD (7) · Charles Brown, MD (7) · Craig Hendrix, MD (7) · Mouen A Khashab, MD (7) · Roland R Griffiths, Ph.D. (7)
PMID 42560883, PMID 29281579, PMID 31723056, PMID 34453519, PMID 18565399, PMID 21087331, PMID 21782353, PMID 22041255, PMID 22267750, PMID 25022541, PMID 25858004, PMID 28007445, PMID 28292764, PMID 28800895, PMID 29747583, PMID 30340648, PMID 30352714, PMID 31643128, PMID 32628945, PMID 33079196, PMID 33760713, PMID 34057734, PMID 34242666, PMID 34255068, PMID 34937780, PMID 35042101, PMID 35314069, PMID 35579938, PMID 35724253, PMID 35998103, PMID 36094829, PMID 36208817, PMID 36716451, PMID 36907833, PMID 37287104, PMID 37318215, PMID 37379584, PMID 38094930, PMID 38236223, PMID 39240566, PMID 39252005, PMID 40303266, PMID 40342086, PMID 40780143, PMID 40970353, PMID 41995596, PMID 42054680, PMID 10382797, PMID 10493481, PMID 10604470
R01DA019934 (6), P50MH115842 (5), R01DA003890 (5), P50MD017348 (4), P30AG021334 (3), P30AI094189 (3), P30NR018093 (3), P50AA027054 (3), R01AG056587 (3), R01DA019497 (3), R01DA043475 (3), R01HL061912 (3), U01AI138897 (3), U19AI070345 (3), U19AI113127 (3)