38 completed, 7 unknown, 6 terminated, 3 active not recruiting. 16 Phase 3, 15 Not applicable, 14 Phase 2, 3 Phase 1, 2 Phase 4.
Follow Bunion: new trials by email Literature Review of Bunion trials Research Report on Bunion
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 3 Bunionectomy Study CPL-01, saline placebo - Postoperative Pain, Bunion | Phase 3 | Not yet recruiting | Cali Pharmaceuticals LLC | 112 | 2027-03-01 | 2026-10-21 |
| Postsurgical Analgesia After Unilateral Bunionectomy AMT-143, Saline (NaCl 0,9 %) (placebo) - Bunionectomy, Bunion | Phase 2 | Not yet recruiting | AmacaThera Inc. | 60 | 2026-12-01 | 2026-10-22 |
| A Study of TLC590 for Postsurgical Pain Following Bunionectomy TLC590, Liposomal Bupivacaine, Saline Placebo - Postoperative Pain | Phase 3 | Active not recruiting | TLC Biopharmaceuticals, Inc. | 304 | 2025-11-17 | 2026-07-02 |
| Association of Q Angle and Bunion Deformity of High Heel Wearing Females of Office Working in Lahore Bunion (Diagnosis) | Completed | Superior University | 80 | 2024-11-01 | 2025-09-05 | |
| Proximal Metatarsal Osteotomy in Correction of Hallux Valgus Hallux Valgus and Bunion | Unknown | Assiut University | 15 | 2024-10-10 | 2024-09-04 | |
| Prospective Study of Minimally Invasive Lapidus Procedure for Hallux Valgus Deformities Minimally invasive lapidus procedure with no arthroscopy, Minimally invasive lapidus procedure with arthroscopy - Hallux Valgus and Bunion | Not applicable | Not yet recruiting | St. Paul's Hospital, Canada | 58 | 2024-10-01 | 2024-08-26 |
| Epidemiology of Bunion and Risk Factors epidemiology - Hallux Valgus and Bunion | Unknown | Assiut University | 2000 | 2024-07-24 | 2024-03-28 | |
| Hallux Abductus Valgus and Extensor Hallux Longus; Treatment by MIS Surgery Minimally invasive procedures for the Hallux Abductus Valgus., Minimally invasive procedures for the Hallux Abductus Valgus and a zig-zag tenotomy for the extensus hallux longus. - Hallux Valgus and Bunion | Completed | Fundación Universidad Católica de Valencia San Vicente Mártir | 30 | 2024-02-01 | 2025-02-17 | |
| CPL-01 in the Management of Postoperative Pain After Bunionectomy Local anesthetic injection of CPL-01, Naropin, 0.5% Injectable Solution, Placebo - Bunion, Post-operative Pain | Phase 3 | Completed | Cali Pharmaceuticals LLC | 616 | 2023-05-22 | 2026-04-30 |
| Clinical Trial on Patient-Specific-Instrumentation Assisted Lapidus Fusion for Hallux Valgus PSI Lapidus, Conventional Lapidus - Hallux Valgus, Bunion | Not applicable | Unknown | Chinese University of Hong Kong | 54 | 2023-04-01 | 2023-09-25 |
| A Study to Evaluate Analgesic Efficacy and Safety of PRF-110 for Post-surgical Pain Ropivacaine - Bunion | Phase 3 | Completed | PainReform LTD | 428 | 2023-03-13 | 2024-09-19 |
| Post-Operative Pain and Opioid Reduction Trial After Bunionectomy Analgesic Non Narcotic - Hallux Valgus and Bunion | Phase 2 | Completed | Cali Pharmaceuticals LLC | 73 | 2022-06-14 | 2023-01-11 |
| Patient Reported Function Following Combined First MTP and First TMT Arthrodesis. Lapiplasty - Hallux Valgus | Not applicable | Completed | Midwest Bunion Center, LLC | 31 | 2022-03-29 | 2023-10-23 |
| Early Weight-Bearing After the Lapiplasty Mini-Incision Procedure (Mini3D) Treatment of Hallux Valgus - Hallux Valgus, Bunion | Not applicable | Terminated | Treace Medical Concepts, Inc. | 123 | 2021-09-17 | 2026-04-20 |
| LSTR in Chevron Osteotomy Chevron osteotomy bunion surgery with lateral soft tissue release - Bunion | Not applicable | Active not recruiting | The Methodist Hospital Research Institute | 200 | 2021-06-24 | 2026-09-08 |
| Study to Evaluate the Safety and Tolerability of FX301 in Patients Undergoing Bunionectomy FX301, Normal Saline - Pain, Postoperative, Bunion | Phase 1 | Completed | Pacira Pharmaceuticals, Inc | 85 | 2021-03-15 | 2022-08-26 |
| Ultrasound-Guided Percutaneous Peripheral Nerve Stimulation: A Department of Defense Funded Pragmatic Clinical Trial Peripheral Nerve Stimulation, Sham - Rotator Cuff Repair, Ankle Arthroplasty or Arthrodesis | Not applicable | Completed | University of California, San Diego | 250 | 2021-01-26 | 2026-09-24 |
| Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL, EXPAREL Admixed With Bupivacaine HCl vs. Bupivacaine HCl Administered as Combined Sciatic and Saphenous Nerve Blocks for Postsurgical Analgesia in Subjects Undergoing Lower Extremity Surgeries Exparel, Bupivacaine Hydrochloride - Lower Extremity Surgery, Bunion | Phase 3 | Completed | Pacira Pharmaceuticals, Inc | 121 | 2020-10-20 | 2022-07-18 |
| Liposomal Bupivacaine Versus Bupivacaine Plain for Operative Pain Management of Forefoot Surgery Liposomal bupivacaine, Bupivacaine HCl - Liposomal Bupivacaine, Postoperative Pain | Phase 4 | Unknown | Alexandra Black | 100 | 2020-06-16 | 2021-02-25 |
| Phase 3, Randomized, Double Blinded, Active Controlled, Multicenter Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL Admixed With Bupi vs. Bupi Only Administered as Combined Sciatic and Adductor Canal Nerve Block for Postsurgical Analgesia in Lower Extremity Surgeries EXPAREL 13.3Mg/mL Suspension for Injection, Bupivacaine Hydrochloride - Bunion, Metatarsophalangeal Fusion | Phase 3 | Withdrawn | Pacira Pharmaceuticals, Inc | 2020-06-15 | 2020-08-13 |
Showing 20 of 58. Sign in to see all of them.
Hallux Valgus (27) · Pain, Postoperative (16) · Pain (7) · Acute Pain (6) · Agnosia (6) · Ankylosis (4) · Arthralgia (2) · Arteriovenous Fistula (1) · Arthritis, Rheumatoid (1) · Dilatation, Pathologic (1) · Disease (1) · Foot Injuries (1) · Hallux Rigidus (1) · Hemorrhage (1)
Foot Deformities (58) · Foot Deformities, Acquired (58) · Musculoskeletal Diseases (58) · Pathological Conditions, Signs and Symptoms (26) · Neurologic Manifestations (23) · Signs and Symptoms (23) · Pathologic Processes (18) · Pain (16) · Postoperative Complications (16) · Joint Diseases (9) · Nervous System Diseases (7) · Neurobehavioral Manifestations (6) · Perceptual Disorders (6) · Skin and Connective Tissue Diseases (2) · Arteriovenous Malformations (1)
Bupivacaine (7) · Oxycodone (3) · Ropivacaine (3) · Injections (2) · Saline Solution (2) · Sodium Chloride (2) · Tapentadol (2) · 7-propyltheophylline dopamine (1) · Analgesics, Non-Narcotic (1) · Analgesics, Opioid (1) · Aprepitant (1) · Arthroscopy (1) · Dexmedetomidine (1) · Fracture Fixation, Intramedullary (1) · Ketorolac (1)
Pacira Pharmaceuticals, Inc (5) · Baudax Bio (4) · Heron Therapeutics (4) · Cali Pharmaceuticals LLC (3) · Assiut University (2) · Chinese University of Hong Kong (2) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (2) · Mallinckrodt (2) · Paragon 28 (2) · Treace Medical Concepts, Inc. (2) · iX Biopharma Ltd. (2) · Alexandra Black (1) · AmacaThera Inc. (1) · Anesiva, Inc. (1) · Asklepieion Voulas General Hospital (1)
United States (37) · Hong Kong (3) · Canada (2) · Spain (2) · Australia (1) · Austria (1) · Belgium (1) · France (1) · Greece (1) · Italy (1) · Pakistan (1) · South Korea (1) · Taiwan (1)
Erol Onel (2) · Neil Singla, MD (2) · Samuel KK Ling, MBChB (2) · Abdulrahman M Hussein Mohamed (1) · Alastair Younger (1) · Brian M Ilfeld, MD, MS (1) · Chien-Chung Kuo (1) · Christopher Hyer, DPM (1) · Dane Wukich, MD (1) · Elliot Hershman, MD (1) · Emily A Cook, DPM, MPH (1) · Ettore Vulcano, MD (1) · James B Jones, MD, PharmD (1)
PMID 30737315, PMID 16325100, PMID 19203298, PMID 19445652, PMID 20488776, PMID 20678710, PMID 20710024, PMID 21842428, PMID 22292592, PMID 22900785, PMID 24351079, PMID 25133962, PMID 25157951, PMID 26361518, PMID 26752780, PMID 27919259, PMID 28580264, PMID 28870735, PMID 29310149, PMID 31113830, PMID 31843865, PMID 32600562, PMID 34284613, PMID 34483396, PMID 39428602, PMID 41316331