28674 completed, 6578 unknown, 5837 recruiting, 2521 not yet recruiting. 26101 Not applicable, 5686 Phase 2, 3650 Phase 3, 3062 Phase 1, 2930 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Cannabidiol on Psychiatric Symptoms, Cognition, and Cannabis Consumption in Cannabis Users With Recent-Onset Psychosis Cannabidiol (CBD), Placebo - Schizophrenia Spectrum Disorders, Cannabis Use | Phase 2 | Withdrawn | University of Maryland, Baltimore | 2050-01-01 | 2021-04-19 | |
| Buddhist Awareness Training Program and Qigong Psychosocial Interventions for People With Insomnia Psychosocial intervention - Insomnia, Randomised Controlled Trial | Not applicable | Suspended | College of Professional and Continuing Education Limited | 86 | 2030-01-01 | 2026-03-19 |
| Tau Pathology in the Brain After Hip or Knee Replacement Surgery Hip or Knee Arthroplasty Under Spinal Anesthesia - Postoperative Cognitive Dysfunction, Alzheimer Disease | Recruiting | Uppsala University Hospital | 30 | 2029-04-01 | 2026-10-15 | |
| Efficacy of Mindfulness in PREventing Progression to Psychosis in Individuals With an Ultra High Risk for Psychosis MBTP : Mindflulness based training for psychosis - Clinical High Risk for Psychosis (CHR) | Not applicable | Not yet recruiting | Centre Psychothérapique de Nancy | 270 | 2029-04-01 | 2026-03-25 |
| Post-surgical Delirium in Patients Undergoing Radical Cystectomy. Radical cystectomy. - Delirium, Radical Cystectomy | Not yet recruiting | University of Alexandria | 100 | 2028-11-25 | 2025-04-03 | |
| Post-surgical Delirium in Patients Undergoing Open Heart Surgery. Open heart surgery - Delirium, Open Heart Surgery | Not yet recruiting | University of Alexandria | 300 | 2028-10-01 | 2025-04-03 | |
| Personalized Pharmaco-Lifestyle Interventions for Severe Mental Illnesses (LIFETRAIN) Semaglutide (SEMA), Exercise module, Anti-inflammatory diet module - Severe Mental Illness, Depression / Major Depressive Disorder | Not applicable | Not yet recruiting | Ludwig-Maximilians - University of Munich | 140 | 2028-10-01 | 2026-05-14 |
| A Hybrid Type 1 Randomized Controlled Trial of an Online and Text-Messaging Intervention to Prevent Alcohol and Cannabis Initiation, Escalation, and Consequences Among First-Year College Students Online and Text Message Intervention - Alcohol, Cannabis | Not applicable | Not yet recruiting | The University of Texas at Arlington | 800 | 2028-09-01 | 2026-10-30 |
| RISE for PTSD and Substance Use Disorder in Veterans Written Exposure Therapy, Cognitive Behavioral Therapy for Substance Use Disorders (skill components), Cognitive Behavioral Therapy for Substance Use Disorders - Stress Disorders, Post-Traumatic, Substance-Related Disorders | Not applicable | Not yet recruiting | VA Office of Research and Development | 30 | 2028-08-01 | 2026-10-29 |
| The Development of a Transdiagnostic Intervention to Improve Social Functioning and Intimate Relationships Among Veterans Acceptance and Commitment Therapy for Social Health, Achievement, and Relationship Effectiveness (ACT-SHARE) - Alcohol Problems, Post-Traumatic Stress Disorder | Not applicable | Not yet recruiting | VA Office of Research and Development | 29 | 2028-07-03 | 2025-11-19 |
| Dynamic Treatment Regimes for Opioid Use Disorder Medication for opioid use disorder, psychotherapy - Opioid Use Disorder | Phase 2 | Not yet recruiting | Brigham and Women's Hospital | 75 | 2028-07-01 | 2025-11-04 |
| MRI Technical Development and Applications in Kidney Disease Chronic Kidney Diseases, Kidney Transplantation | Not yet recruiting | University of Minnesota | 180 | 2028-06-30 | 2026-04-13 | |
| Whole-Body Hyperthermia for Mood and Anxiety Disorders Whole-Body Hyperthermia, fMRI - Postpartum Depression, Mood Disorders | Not applicable | Not yet recruiting | Weill Medical College of Cornell University | 240 | 2028-06-01 | 2026-06-23 |
| Department of Defense PTSD Adaptive Platform Trial - Intervention D - SLS-002 Intervention D SLS-002, Intervention D Placebo - Post Traumatic Stress Disorder | Phase 2 | Suspended | Global Coalition for Adaptive Research | 200 | 2028-05-01 | 2026-05-20 |
| Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in Veterans Integrated care - Opioid Use Disorder, HIV | Not applicable | Not yet recruiting | VA Office of Research and Development | 60 | 2028-04-03 | 2026-04-24 |
| Cognitive Neurocomputational Task Reliability and Clinical Applications Consortium: Study 2 Motion Perception Task, Sine Wave Speech Task, Volatility Task - SCHIZOPHRENIA 1 (Disorder), Schizo Affective Disorder | Not applicable | Not yet recruiting | Washington University School of Medicine | 325 | 2028-04-01 | 2026-10-23 |
| Smartphone App for Adolescents With Idiopathic Scoliosis DinSkoliose smartphone application - Adolescence Idiopathic Scoliosis, AIS | Not applicable | Not yet recruiting | Oslo Metropolitan University | 30 | 2028-04-01 | 2026-07-07 |
| RCT: Trazodone vs Quetiapine vs Placebo for Treating ICU Delirium (TraQ) Trazodone, Quetiapine, Placebo - Delirium, Morality | Phase 4 | Withdrawn | University of Southern California | 2028-03-01 | 2026-05-04 | |
| INNOV5-MH-MAROC: Integrated Mental Health Care for Adolescents and Adults in Primary Care Centers and Schools in Morocco INNOV5 Integrated Mental Health Program, Enhanced Treatment as Usual (TAU+) - Depression in Adolescence, Depression in Adults | Not applicable | Not yet recruiting | Swiss Medical Academy Maroc | 146 | 2028-03-01 | 2025-12-02 |
| Braining - Evaluation of Acute Effects of Physical Exercise Braining - Psychiatric Disorder | Not applicable | Not yet recruiting | Region Stockholm | 30 | 2028-01-01 | 2026-02-06 |
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Anxiety Disorders (7172) · Depression (5285) · Alzheimer Disease (3881) · Cognitive Dysfunction (3778) · Schizophrenia (3474) · Depressive Disorder, Major (2966) · Sleep Initiation and Maintenance Disorders (2673) · Stress Disorders, Post-Traumatic (2651) · Dementia (2257) · Substance-Related Disorders (2232) · Attention Deficit Disorder with Hyperactivity (1792) · Autism Spectrum Disorder (1712) · Alcoholism (1667) · Bipolar Disorder (1664)
Nervous System Diseases (15754) · Pathological Conditions, Signs and Symptoms (11619) · Behavior (11281) · Neurocognitive Disorders (10350) · Signs and Symptoms (9745) · Central Nervous System Diseases (7774) · Neurologic Manifestations (7685) · Brain Diseases (7580) · Chemically-Induced Disorders (7237) · Behavioral Symptoms (6620) · Mood Disorders (5559) · Neurodevelopmental Disorders (5244) · Substance-Related Disorders (4961) · Neurodegenerative Diseases (4927)
Cognitive Behavioral Therapy (893) · Therapeutics (796) · Transcranial Magnetic Stimulation (497) · Exercise (466) · Transcranial Direct Current Stimulation (437) · Risperidone (387) · Aripiprazole (303) · Ketamine (298) · Surveys and Questionnaires (290) · Escitalopram (282) · Methylphenidate (275) · Quetiapine Fumarate (271) · Olanzapine (260) · Control Groups (259) · Standard of Care (257)
Yale University (599) · Massachusetts General Hospital (578) · VA Office of Research and Development (578) · New York State Psychiatric Institute (361) · University of California, Los Angeles (355) · Stanford University (353) · Johns Hopkins University (350) · National Institute on Drug Abuse (NIDA) (342) · University of Pennsylvania (329) · University of California, San Francisco (301) · Assistance Publique - Hôpitaux de Paris (296) · Eli Lilly and Company (275) · National Institute of Mental Health (NIMH) (271) · University of Pittsburgh (263) · Centre for Addiction and Mental Health (261)
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