73 completed, 29 unknown, 23 recruiting, 12 withdrawn. 103 Not applicable, 9 Phase 3, 8 Phase 4, 6 Phase 2, 4 Phase 1.
Follow Phantom Limb: new trials by email Literature Review of Phantom Limb trials Research Report on Phantom Limb
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Alcohol Neurolysis and Capsaicin for Postamputation Pain (PAP) Injection of alcohol near neuroma, Lidocaine 2% injection, Injection of capsaicin 150 mcg per mL if relief with lidocaine 2% - Postamputation Pain | Not applicable | Not yet recruiting | Northwestern University | 120 | 2026-10-31 | 2026-08-18 |
| Training Independent Muscle Activation From a Common Source amputation or revision procedure with additional RPNI construction - Amputation | Not applicable | Recruiting | Brigham and Women's Hospital | 10 | 2026-09-01 | 2026-09-21 |
| Post-Amputation Stump Infection as a Predictor of Persistent Residual Limb Pain: A Prospective Cohort Study Residual Limb Pain, Stump Pain | Not yet recruiting | Ukrainian Society of Regional Anesthesia and Pain Therapy | 150 | 2026-06-23 | 2026-06-03 | |
| Botulinum Toxin Type A Versus Local Anesthetic Injection for Chronic Neuroma Pain After Combat-Related Amputation Botulinum Toxin Type A (BoNT-A), Local Anesthetic Solution - Chronic Pain Due to Injury, Neuroma of Lower Limb | Not applicable | Completed | Ukrainian Society of Regional Anesthesia and Pain Therapy | 100 | 2026-05-30 | 2026-10-27 |
| Proximal Nerve Cryoablation Versus Perineuroma Cryoablation for Chronic Neuroma Pain After Combat-Related Amputation Perineuroma Cryoablation, Proximal Nerve Cryoablation - Neuroma, Cryoablation | Not applicable | Completed | Ukrainian Society of Regional Anesthesia and Pain Therapy | 50 | 2026-05-23 | 2026-10-26 |
| Tourniquet Exposure and Risk of Chronic Pain After Severe Limb Trauma Pain, Pain After Surgery | Completed | Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans) | 150 | 2026-03-15 | 2026-10-26 | |
| Kinematics-Based Prediction of Chronic Pain After Combat-Related Extremity Trauma Residual Limb Pain, Post-Traumatic Limb Pain | Completed | Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans) | 100 | 2026-03-12 | 2026-10-16 | |
| Amputations in Childhood and Neuropathic Pain Pediatric, Neuropathic Pain | Recruiting | Hopitaux de Saint-Maurice | 50 | 2026-02-19 | 2026-02-23 | |
| Silencing Neuroma Pain-Botulinum Toxin Versus Local Anesthetic Injection Botulinium toxin type A injection, Local Anesthesia - Pain Management, Pain | Not applicable | Not yet recruiting | Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans) | 100 | 2026-02-15 | 2026-02-25 |
| Prophylactic TBR on Phantom Limb Pain Targeted Brain Rehabilitation - Phantom Limb Pain After Amputation | Not applicable | Enrolling by invitation | OrthoCarolina Research Institute, Inc. | 50 | 2026-02-05 | 2026-04-06 |
| Clinical Trial Exploring the Outpatient Treatment of Phantom Limb Pain With Ketamine Administration in a Six Month Study With a Minimum Remission Period of 7 Days Between Treatment Session. 25-30 Subjects With an Ongoing History of Significant PLP.--FDA and IRB Approved. IM ketamine in dose finding and then continuation - Phantom Limb Syndrome With Pain | Phase 2 / Phase 3 | Recruiting | The Ketamine Research Foundation | 30 | 2026-01-15 | 2026-03-18 |
| Early Postoperative Pain Following a Limb Amputation Pain assessment - Amputation, Surgical, Pain Management | Recruiting | Istituto Ortopedico Rizzoli | 150 | 2026-01-09 | 2026-02-06 | |
| Intrathecal Dexmedetomidine and Acute Neuropathic Pain After Lower Limb Amputation Hyperbaric Bupivacaine plus Saline, Hyperbaric Bupivacaine plus Dexmedetomidine - Phantom Limb Pain, Neuropathic Pain | Not applicable | Completed | Universidad Juárez Autónoma de Tabasco | 30 | 2025-09-30 | 2026-10-21 |
| Efficacy and Mechanisms of Virtual Reality Treatment of Phantom Leg Pain.Home-Based Treatment Active Virtual Reality Treatment - Phantom Pain Following Amputation of Lower Limb, Amputation | Not applicable | Recruiting | Albert Einstein Healthcare Network | 44 | 2025-06-16 | 2025-08-08 |
| Clinical Application Observation on the Evaluation of Phantom Limb Pain With the Suralis System Vibrotactile sensory feedback - Phantom Limb Pain After Amputation, Lower Limb Amputation Above Knee | Not applicable | Recruiting | Median | 20 | 2025-04-01 | 2026-01-07 |
| Preventing Chronification of Phantom Limb Pain Through Mirror Therapy in Conjunction With tDCS Trans Direct-Cranial Stimulation (tDCS), Mirror therapy - Phantom Limb Pain After Amputation | Not applicable | Recruiting | University of Haifa | 108 | 2025-03-25 | 2025-09-08 |
| Prevention of PostAmputation Pain With Targeted Muscle Reinnervation Targeted Muscle Reinnervation (TMR), Standard neurectomy - Amputation, Surgical, Phantom Limb Pain | Not applicable | Recruiting | Leiden University Medical Center | 203 | 2024-12-31 | 2025-09-19 |
| Evaluation of Neuroprosthesis with Sensory Feedback for Modulation of Phantom Limb Pain and Enhancing Quality of Life Peripheral Nerve Stimulation, Spinal cord stimulation, Dorsal Root Ganglion Stimulation - Phantom Limb Pain | Not applicable | Recruiting | Skolkovo Institute of Science and Technology | 50 | 2024-12-01 | 2024-11-25 |
| Feasibility of Using an App for Managing Phantom Limb Pain Associated with Combat Injury in Ukraine (PAMELA) non-pharmacological app - Amputation, Traumatic, Pain, Phantom | Not yet recruiting | Winfried Meißner | 200 | 2024-10-15 | 2024-09-19 | |
| Peripheral Magnetic Stimulation (PMS) Effects on Somatosensory Perception in Patients with Upper Limb Amputation Procedure: Peripheral Magnetic Stimulation (PMS), Electroencephalography (EEG) - Phantom Limb Pain | Not applicable | Recruiting | Skolkovo Institute of Science and Technology | 30 | 2024-09-16 | 2025-02-07 |
Showing 20 of 159. Sign in to see all of them.
Neuralgia (28) · Pain (24) · Chronic Pain (21) · Agnosia (12) · Amputation, Traumatic (11) · Complex Regional Pain Syndromes (6) · Neuroma (5) · Pain, Postoperative (5) · Spinal Cord Injuries (4) · Stroke (4) · Wounds and Injuries (4) · Multiple Sclerosis (3) · Acute Pain (2) · Arthritis, Rheumatoid (2)
Neurologic Manifestations (159) · Pathologic Processes (159) · Pathological Conditions, Signs and Symptoms (159) · Perceptual Disorders (159) · Postoperative Complications (159) · Signs and Symptoms (159) · Nervous System Diseases (158) · Neurobehavioral Manifestations (158) · Pain, Postoperative (154) · Pain (135) · Neuromuscular Diseases (33) · Peripheral Nervous System Diseases (32) · Wounds and Injuries (20) · Central Nervous System Diseases (8) · Cardiovascular Diseases (7)
Mirror Movement Therapy (7) · Transcranial Direct Current Stimulation (5) · Lidocaine (4) · Acupuncture Therapy (3) · Cryosurgery (3) · Transcranial Magnetic Stimulation (3) · Control Groups (2) · Pregabalin (2) · Spinal Cord Stimulation (2) · Amputation, Surgical (1) · Analgesia (1) · Analgesia, Epidural (1) · Anesthesia, Local (1) · Anesthesia, Spinal (1) · Blood Specimen Collection (1)
University of California, San Diego (7) · VA Office of Research and Development (4) · Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans) (3) · Henry M. Jackson Foundation for the Advancement of Military Medicine (3) · Lee Fisher, PhD (3) · Skolkovo Institute of Science and Technology (3) · Spaulding Rehabilitation Hospital (3) · The University of Texas Health Science Center, Houston (3) · Ukrainian Society of Regional Anesthesia and Pain Therapy (3) · Albert Einstein Healthcare Network (2) · Apurano Pharmaceuticals GmbH (2) · Artur Biktimirov (2) · Brigham and Women's Hospital (2) · Duke University (2) · Integrum (2)
United States (74) · Canada (9) · Israel (7) · Ukraine (7) · Germany (6) · Italy (6) · Sweden (6) · United Kingdom (6) · France (5) · Russia (5) · Denmark (4) · Netherlands (4) · Switzerland (4) · Belgium (3) · Spain (3)
Lee Fisher, PhD (3) · Max Ortiz Catalan, PhD (3) · Sheng Li, MD, PhD (3) · Brian Ilfeld, M.D., M.S. (2) · Brian Ilfeld, MD, MS (2) · Glenn Gaston, MD (2) · Jack W Tsao, MD (2) · Lee E Fisher, PhD (2) · Matthew J Carty, MD (2) · Wassim Raffoul, Professor (2) · Alexander Gardetto, Doz.Dr (1) · Alparslan Turan, MD (1) · An-Fu Hsiao, M.D., Ph.D. (1) · Andreas Schwarzer, Dr. Dr. (1)
PMID 28850360, PMID 11438246, PMID 12849487, PMID 16691088, PMID 18376170, PMID 18648238, PMID 21368651, PMID 21439051, PMID 22981809, PMID 23740337, PMID 24616655, PMID 24769029, PMID 24969474, PMID 25439709, PMID 25873101, PMID 26324857, PMID 27383993, PMID 27782861, PMID 27916234, PMID 28051969, PMID 28736545, PMID 28830632, PMID 30012784, PMID 30954936, PMID 31501600, PMID 31740443, PMID 33021563, PMID 33417885, PMID 34314392, PMID 34761694, PMID 35152915, PMID 35461007, PMID 36006951, PMID 36273191, PMID 36627156, PMID 3670870, PMID 36894197, PMID 37100202, PMID 37276273, PMID 37332478, PMID 37947407, PMID 38363591, PMID 38378671, PMID 38526122, PMID 38557950, PMID 38622634, PMID 38860215, PMID 39094627, PMID 39250328, PMID 39320284
R01HD104158 (2), 1IK2RX004805-01A1 (1), 1UH3NS100541-01A1 (1), 2017 (1), I21RX004410 (1), P2CHD086844 (1), UH3NS100541 (1), UH3NS109556 (1)