101 withdrawn. 101 Phase 2, 14 Phase 1, 12 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 101 | Withdrawn 101 |
| Phase 1 | 14 | Withdrawn 14 |
| Phase 3 | 12 | Withdrawn 12 |
Follow Pain: new trials by email Literature Review of Pain trials Research Report on Pain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ketamine and Midazolam Infusions for CRPS: Feasibility Study Ketamine, Midazolam, Normal Saline - Complex Regional Pain Syndromes | Phase 2 | Withdrawn | Stanford University | 2099-01-01 | 2024-11-22 | |
| Efficacy and Safety of Canadá Association in the Treatment of Chronic Pain Canadá, Canadá placebo, Dipyrone - Pain, Chronic | Phase 2 | Withdrawn | EMS | 2026-09-01 | 2023-09-08 | |
| Post-Operative Steroids After Sleep Surgery 8mg dexamethasone - Obstructive Sleep Apnea | Phase 2 | Withdrawn | Medical University of South Carolina | 2026-07-01 | 2026-10-06 | |
| Dronabinol As an Adjunct for Reducing Pain (DARP)-Texas Children's Hospital Dronabinol Capsules, Placebo - Endometriosis, Endometriosis Related Pain | Phase 2 | Withdrawn | Baylor College of Medicine | 2026-04-01 | 2026-03-13 | |
| Prescribing Lorazepam for IUD Insertion: Pilot Feasibility Study Lorazepam 1 mg, Ibuprofen 800 mg - Pain, IUD | Phase 2 | Withdrawn | University of Wisconsin, Madison | 2025-10-01 | 2025-10-30 | |
| Safety & Efficacy of Intranasal Dexmedetomidine, Fentanyl & Midazolam in the Pediatric Emergency Room Intranasal Dexmedetomidine (4 mcg/kg), Intranasal Fentanyl (2 mcg/kg), Intranasal Midazolam (5 mg/kg) - Acute Stress Disorder, Anxiety | Phase 2 | Withdrawn | Nationwide Children's Hospital | 2025-09-01 | 2025-09-10 | |
| Rifaximin for Treatment of Bloating in Children and Adults With Cystic Fibrosis Rifaximin 550 MG Oral Tablet [XIFAXAN], Placebo - Cystic Fibrosis, Abdominal Pain | Phase 2 / Phase 3 | Withdrawn | Wake Forest University Health Sciences | 2025-07-01 | 2025-06-27 | |
| Apply the PD Model of Peripheral Oxytocin Action to a Multimodal Stimulus Oxytocin, Placebo - Pain, Chronic | Phase 2 | Withdrawn | Wake Forest University Health Sciences | 2025-01-01 | 2024-10-26 | |
| Chinese Herbal Medicine for Gynecologic Patients Chinese Herbal Medicine (CHM) supplement, Placebo - Dysmenorrhea | Phase 2 | Withdrawn | Icahn School of Medicine at Mount Sinai | 2024-07-01 | 2024-07-23 | |
| Phenotyping of Idiopathic Pelvic Pain With Real-time Uterine Imaging and Relugolix-Combination Therapy Treatment Relugolix (40 mg) /estradiol (1 mg)/norethisterone acetate (0.5 mg) oral tablet - Pelvic Pain | Phase 2 | Withdrawn | Endeavor Health | 2024-06-01 | 2025-08-28 | |
| Noninvasive Modulation of Chronic Neuropathic Pain Active stimulation using low-frequency ultrasonic transducer, Sham stimulation using low-frequency ultrasonic transducer - Neuropathic Pain, Chronic Pain | Phase 1 / Phase 2 | Withdrawn | University of Utah | 2024-02-10 | 2025-05-22 | |
| Pediatric Postoperative Analgesia Herniorrhaphy Study HTX-011, Bupivacaine HCl, Luer Lock Applicator - Analgesia | Phase 2 | Withdrawn | Heron Therapeutics | 2023-07-01 | 2026-05-12 | |
| Targeting Senescence to Reduce Osteoarthritis Pain and cartilagE Breakdown (ROPE) High-dose/short-duration Fisetin, Low-dose/sustained-duration Fisetin, Oral placebo capsule - Osteoarthritis, Knee | Phase 1 / Phase 2 | Withdrawn | Austin V Stone | 2023-06-01 | 2022-07-29 | |
| Effect of Palmitoylethanolamide on Reducing Opioid Consumption for Below Knee Fracture Fixation Palmitoylethanolamide, Placebo - Tibial Fractures, Fibula Fracture | Phase 2 | Withdrawn | University of California, Irvine | 2023-05-01 | 2023-05-09 | |
| Efficacy and Safety of Tiradentes Association in the Treatment of Acute Pain TIRADENTES ASSOCIATION, DIPYRONE, TRAMADOL - Acute Pain | Phase 2 | Withdrawn | EMS | 2023-03-01 | 2023-09-08 | |
| Efficacy and Safety of Escócia Association in the Treatment of Acute Pain Escócia association, Placebo Ketorolac, Placebo Scopolamine - Acute Pain | Phase 2 | Withdrawn | EMS | 2023-02-01 | 2023-09-08 | |
| Treatment of Frostbite Sequelae With Botulinum Toxin A Botuinum toxin - Cold Hypersensitivity, Vascular System Injuries | Phase 2 | Withdrawn | University Hospital of North Norway | 2022-11-01 | 2024-06-14 | |
| Investigating RELEARN Neurofeedback as Treatment for Chronic Musculoskeletal Pain RELEARN Neurofeedback, Standard care control - Chronic Knee Pain, Chronic Pain | Phase 2 / Phase 3 | Withdrawn | Redo-Neurosystems | 2022-10-05 | 2024-02-06 | |
| Opioid-Free Pain Control Regiment Following Robotic Radical Prostatectomy Tramadol, Gabapentin, Hydrocodone-Acetaminophen - Radical Prostatectomies | Phase 2 / Phase 3 | Withdrawn | Wake Forest University Health Sciences | 2022-08-01 | 2022-09-06 | |
| Failed Endometrial Ablation Treatment With Implantable Progesterone (FEAT) Study Etonogestrel 68mg implant - Abnormal Uterine Bleeding, Dysmenorrhea | Phase 2 | Withdrawn | Saskatchewan Health Authority - Regina Area | 2022-07-01 | 2025-11-25 |
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Pain, Postoperative (12) · Chronic Pain (11) · Neuralgia (9) · Acute Pain (8) · Agnosia (5) · Angina Pectoris (4) · Headache (4) · Low Back Pain (4) · Neoplasms (4) · Angina, Stable (3) · Anxiety Disorders (3) · Depression (3) · Inflammation (3) · Intervertebral Disc Degeneration (3)
Neurologic Manifestations (101) · Pathological Conditions, Signs and Symptoms (101) · Signs and Symptoms (101) · Nervous System Diseases (28) · Pathologic Processes (22) · Neuromuscular Diseases (14) · Musculoskeletal Diseases (13) · Postoperative Complications (13) · Peripheral Nervous System Diseases (12) · Cardiovascular Diseases (9) · Vascular Diseases (9) · Neurobehavioral Manifestations (8) · Mental Disorders (7) · Behavior (6)
Lidocaine (5) · Morphine (5) · Acetaminophen (4) · Bupivacaine (4) · Gabapentin (4) · Ketamine (4) · Fentanyl (3) · Ibuprofen (3) · Ketorolac (3) · Ketorolac Tromethamine (3) · Midazolam (3) · Saline Solution (3) · Standard of Care (3) · Tramadol (3) · Botulinum Toxins, Type A (2)
Wake Forest University Health Sciences (4) · EMS (3) · University of Utah (3) · Adynxx, Inc. (2) · Baylor College of Medicine (2) · Johns Hopkins University (2) · Medical University of South Carolina (2) · Montefiore Medical Center (2) · Nationwide Children's Hospital (2) · Northwestern University (2) · The University of Texas Health Science Center, Houston (2) · University of Minnesota (2) · AFT Pharmaceuticals, Ltd. (1) · Albert Einstein College of Medicine (1) · Allodynic Therapeutics, Inc (1)
United States (58) · Canada (4) · Denmark (3) · Italy (2) · Norway (2) · Switzerland (2) · United Kingdom (2) · Belgium (1) · China (1) · Czechia (1) · Egypt (1) · Greece (1) · Hungary (1) · Israel (1) · Poland (1)
Adam H de Havenon, MD (1) · Alfred E Slonim, MD (1) · Andrew Sherman, MD (1) · Apkar V Apkarian, PhD (1) · Ariana Nelson, MD (1) · Arne J Norheim, PhD (1) · Austin Stone, MD, PhD (1) · Baha Moshiree, MD (1) · Benito Benitez, MD (1) · BinBin Wu, doctor (1) · Brent DeGeorge, MD, PhD (1) · Bruce Kahn, M.D. (1) · Charlotte Richmond, PhD (1) · Christopher E White, MD (1)
PMID 19194764, PMID 19734516, PMID 20627413, PMID 21868066, PMID 22370242, PMID 23370086, PMID 24127913, PMID 25338927, PMID 26808752, PMID 26926875, PMID 28452678, PMID 28509693, PMID 29037377, PMID 29285576, PMID 30054011, PMID 30152015, PMID 30646965, PMID 30877613, PMID 31694924, PMID 32178232, PMID 32583883, PMID 33732434, PMID 35005781, PMID 8656545
2014 (2), 1UG3DA048375-01 (1), 2019 (1), K23NS050485 (1), P01NS041386 (1), P30AG028740 (1), R01DE022746 (1)