123 completed, 23 terminated, 20 unknown, 14 recruiting. 85 Phase 4, 33 Phase 2, 32 Not applicable, 30 Phase 3, 21 Phase 1.
Follow Ketorolac Tromethamine: new trials by email Literature Review of Ketorolac Tromethamine trials Research Report on Ketorolac Tromethamine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Epidural Analgesia Versus Opioid-sparing Analgesia for Open Ventral Hernia Repair With Transversus Abdominis Release Bupivicaine, Fentanyl, Thoracic epidural analgesia - Ventral Hernia, Ventral Hernia Repair | Phase 4 | Recruiting | Northwestern University | 40 | 2026-09-25 | 2026-10-07 |
| Midazolam Alone Versus Midazolam With Ketorolac for Sedation During Flexible Bronchoscopy. Midazolam Alone, Midazolam + ketorolac - Sedation and Analgesia Management in Patients Undergoing Flexible Bronchoscopy | Not applicable | Not yet recruiting | SYED HAIDER ALI | 50 | 2026-01-20 | 2026-01-20 |
| Ketorolac Effects on Post-operative Pain and Lumbar Fusion Ketorolac Tromethamine, Placebo - Lumbar Spinal Fusion | Phase 4 | Recruiting | University of Maryland St. Joseph Medical Center | 140 | 2026-01-01 | 2025-12-22 |
| Comparing Intramuscular Fentanyl and Ketorolac With Nerve of Arnold (NOA) Block for Bilateral Myringotomy Fentanyl, Ketorolac, Nerve of Arnold Block - Postoperative Pain | Phase 4 | Not yet recruiting | University of South Alabama | 300 | 2026-01-01 | 2025-12-11 |
| Analgesic Efficacy of Pre-operative Dose of Ketorolac and Gabapentin Ketorolac Tromethamine 30 MG/ML Prefilled Syringe, Gabapentin, Empty Medication Capsules - Pain, Postoperative, Osteoarthritis, Knee | Phase 2 / Phase 3 | Not yet recruiting | Assiut University | 86 | 2025-08-15 | 2025-08-01 |
| Non-Narcotic Pain Control After ACL Reconstruction dispense of study drug, Ketorolac - ACL - Anterior Cruciate Ligament Rupture, ACL Injuries | Phase 2 | Active not recruiting | The Cleveland Clinic | 30 | 2025-07-15 | 2026-08-24 |
| Oral Ketorolac for IUD Pain Reduction Ketorolac, Placebo - IUD Insertion Pain | Phase 2 | Enrolling by invitation | University of North Carolina, Chapel Hill | 108 | 2025-05-23 | 2026-09-08 |
| Pain Control With Ketorolac and Nerve Block After Wrist and Hand Surgery Toradol, Oxycodone - Surgery, Upper Extremity | Phase 4 | Recruiting | University of Chicago | 120 | 2025-03-17 | 2026-08-19 |
| Low-Dose Short-Term Ketorolac to Reduce Chronic Opioid Use in Orthopaedic Polytrauma Patients Ketorolac Injection, Standard of Care (SOC) Multimodal Analgesia - Orthopaedic Trauma, Chronic Opioid Use | Phase 4 | Recruiting | Massachusetts General Hospital | 458 | 2025-02-28 | 2026-05-14 |
| Effectiveness of Corticosteroid vs Ketorolac Shoulder Injections Ketorolac, Marcaine, Kenalog - Full-thickness Rotator Cuff Tear, Rotator Cuff Tendinitis | Phase 4 | Withdrawn | Michael Khazzam | 2024-11-01 | 2024-11-15 | |
| Ketorolac for Acute Vaso-Occlusive Crisis in Pediatric Sickle Cell Disease Ketorolac - Sickle Cell Disease, Sickle Cell Crisis | Phase 4 | Not yet recruiting | Children's Blood and Cancer Center at Dell Children's Medical Center | 102 | 2024-09-30 | 2024-08-30 |
| Efficacy of NSAID vs. Steroid-NSAID Combo Post-Selective Laser Trabeculoplasty: Phase 4, Single-Center RCT Ketorolac 0.5% Eye Drops, Ketorolac 0.5% and Fluorometholone 0.1% Eye Drops - Open Angle Glaucoma, Ocular Hypertension | Phase 4 | Unknown | St. Joseph's Healthcare Hamilton | 126 | 2024-09-01 | 2024-07-12 |
| Study of Complication Rates in Cataract Surgery Patients Treated With Combined Pre-operative NSAID, OMIDRIA, and Subconjunctival Triamcinolone Acetonide Compared With Peri-operative SOC Omidria, {0.3%-1% Intraocular Solution}, VIGAMOX {0.5% moxifloxacin hydrochloride}, Kenalog {0.4 ml, 10mg/ml, triamcinolone acetonide}, Ketorolac (0.5%) {Toradol}, moxifloxacin (0.5%) {VIGAMOX}, prednisolone acetate (1%) {Pred Forte} - Cataract | Phase 1 / Phase 2 | Recruiting | Inder Paul Singh, M.D. | 94 | 2024-07-10 | 2024-11-29 |
| Haloperidol for Pain Control in Patients With Acute Musculoskeletal Back Pain in the Emergency Department Haloperidol, Ketorolac Tromethamine - Back Pain, Chronic Pain | Phase 4 | Recruiting | Western Michigan University School of Medicine | 75 | 2024-07-09 | 2024-07-10 |
| Intravenous Ketorolac Vs. Morphine In Children With Acute Abdominal Pain Ketorolac Tromethamine, Morphine Sulfate, normal saline - Acute Pain, Abdomen, Acute | Phase 3 | Recruiting | University of Calgary | 495 | 2024-05-27 | 2024-06-24 |
| Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery Dexmedetomidine, Acetaminophen, Ketorolac - Tonsillitis, Post-operative Nausea and Vomiting (PONV) | Not applicable | Completed | Boston Children's Hospital | 62 | 2024-05-09 | 2026-05-18 |
| The Efficiency of Periarticular Multimodal Drug Injection in Pain Management Following Primary Unilateral TKA primary unilateral TKA, Bupivacain, ketorolac - Arthritis Knee, Pain | Not applicable | Completed | Damascus University | 80 | 2024-03-01 | 2026-03-19 |
| Intravenous Ketorolac Administration to Attenuate Post-procedural Pain Associated With Intrauterine Device Placement Ketorolac, Placebo - IUD, Healthy Female | Phase 4 | Unknown | Arkansas Children's Hospital Research Institute | 18 | 2024-02-05 | 2024-07-31 |
| Treatment of Topical Ketorolac Gel in Acute Gouty Flare Ketorolac Tromethamine 15 MG/ML, Ketorolac Tromethamine - Acute Gouty Arthritis, Acute Pain | Phase 1 | Unknown | Novilla Pharmaceuticals | 30 | 2024-02-01 | 2024-02-23 |
| A Randomized Controlled Trial of IV Ketorolac to Prevent Post-ERCP Pancreatitis Ketorolac, Placebo - Pancreatitis | Phase 4 | Withdrawn | University of California, San Francisco | 2023-11-01 | 2022-04-28 |
Showing 20 of 204. Sign in to see all of them.
Pain, Postoperative (48) · Pain (33) · Agnosia (16) · Migraine Disorders (10) · Acute Pain (7) · Emergencies (7) · Osteoarthritis, Knee (6) · Cataract (5) · Kidney Calculi (5) · Macular Edema (5) · Renal Colic (5) · Appendicitis (4) · Back Pain (4) · Headache (4) · Osteoarthritis (4)
Egalet Ltd (11) · Azad University of Medical Sciences (4) · Mayo Clinic (4) · University of Utah (4) · EMS (3) · Emory University (3) · Henry Ford Health System (3) · Montefiore Medical Center (3) · Queen's University (3) · The Cleveland Clinic (3) · University of Calgary (3) · Alberta Children's Hospital (2) · American Regent, Inc. (2) · Antonios Likourezos (2) · Assiut University (2)
United States (112) · Canada (14) · United Kingdom (7) · Egypt (6) · Iran (6) · Brazil (3) · China (3) · Denmark (3) · New Zealand (3) · South Korea (3) · Australia (2) · Belgium (2) · Italy (2) · Mexico (2) · Norway (2)
Lincoln Bynum, MD (5) · Cyril Clarke, BSc MB BS MFPM (4) · Nahid Mohammadzadeh Akhlaghi, DDS,MDS (3) · Toufic R Jildeh, MD (3) · Bryce Weber, MD FRCSC (2) · Daniel S Tsze, MD, MPH (2) · Edward L Davis, M.D. (2) · Justin Haller, MD (2) · Michael Khazzam, MD (2) · Mitchell R. Humphreys, M.D. (2) · Mohamed Eltorki, MBChB (2) · Sergey Motov, MD (2) · William Trattler, MD (2) · Alicia Chang, MD (1)
PMID 23058854, PMID 24976224, PMID 10100293, PMID 11495717, PMID 12629531, PMID 17306626, PMID 17456651, PMID 19093703, PMID 19135997, PMID 19209273, PMID 19535182, PMID 20226624, PMID 20736233, PMID 2082307, PMID 21119516, PMID 21199130, PMID 21236454, PMID 23121612, PMID 23143939, PMID 23179562, PMID 23567060, PMID 23669270, PMID 23937996, PMID 24706022, PMID 25534654, PMID 26329661, PMID 2666928, PMID 26802501, PMID 2689472, PMID 27382251, PMID 27993418, PMID 28052951, PMID 28238158, PMID 28376873, PMID 28770108, PMID 28797652, PMID 29088038, PMID 29565947, PMID 29709398, PMID 30338261, PMID 30589514, PMID 30737315, PMID 30770244, PMID 30822800, PMID 31669738, PMID 31800611, PMID 31833000, PMID 33193995, PMID 33805916, PMID 34569278
2008 (2), UL1TR000135 (2), 2009 (1), R01HL144781 (1), U54HL070588 (1)