741 completed, 129 unknown, 62 terminated, 55 recruiting. 440 Phase 1, 236 Phase 4, 197 Not applicable, 105 Phase 2, 95 Phase 3.
Follow Midazolam: new trials by email Literature Review of Midazolam trials Research Report on Midazolam
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ketamine and Midazolam Infusions for CRPS: Feasibility Study Ketamine, Midazolam, Normal Saline - Complex Regional Pain Syndromes | Phase 2 | Withdrawn | Stanford University | 2099-01-01 | 2024-11-22 | |
| A Clinical Trial of MK-6916 With Midazolam and Rosuvastatin in Healthy Participants (MK-6916-012) Midazolam, Rosuvastatin, MK-6916 - Healthy | Phase 1 | Not yet recruiting | Merck Sharp & Dohme LLC | 18 | 2026-11-30 | 2026-10-07 |
| Impact on Delirium of the Use of DEXmedetomidine as First-line Sedation in PEDIAtric Intensive Care Dexmedetomidine, Midazolam - Delirium in the Intensive Care Unit | Phase 3 | Not yet recruiting | University Hospital, Tours | 266 | 2026-11-15 | 2026-09-28 |
| Efficacy of Intravenous Midazolam-Ketamine Combination Versus Placebo for Prevention of Post-Spinal Shivering in Elective Cesarean Section Midazolam and Ketamine, 0.9% Sodium Chloride - Shivering, Post-Spinal Shivering | Phase 4 | Not yet recruiting | Assiut University | 120 | 2026-11-01 | 2026-10-02 |
| DDI Study of ECC0509 With Metformin, Midazolam, and Caffeine ECC0509, Metformin, Caffeine - Steatohepatitis, Nonalcoholic, Osteo Arthritis | Phase 1 | Not yet recruiting | Eccogene | 40 | 2026-11-01 | 2026-10-14 |
| Predicting Response and Exposure Changes in Cirrhosis for Effectiveness Five-Drug CYP Probe Cocktail - Liver Cirrhosis | Not applicable | Not yet recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 45 | 2026-11-01 | 2026-08-11 |
| A Study to Assess the Potential CYP3A Induction Effect of Brensocatib on the Pharmacokinetics (PK) of Midazolam in Healthy Participants Brensocatib, Midazolam - Healthy Volunteers | Phase 1 | Not yet recruiting | Insmed Incorporated | 26 | 2026-10-29 | 2026-10-05 |
| Comparative Evaluation of Intranasal Atomized Midazalom Combined With Nitrous Oxide Versus Nitrous Oxide Monotherapy Midazolam (Intranasal), Nitrous oxide/oxygen inhalation sedation alone, Intranasal normal saline placebo - Dental Anxiety in Children, Child Behaviour | Not applicable | Not yet recruiting | Shaheed Zulfiqar Ali Bhutto Medical University | 68 | 2026-10-15 | 2026-10-15 |
| A Study Comparing Oral Ketamine With Oral Midazolam for the Treatment of Major Depressive Episodes Oral ketamine, Oral midazolam - Major Depressive Episode | Phase 3 | Not yet recruiting | Jawaharlal Institute of Postgraduate Medical Education & Research | 220 | 2026-10-01 | 2026-10-01 |
| A Multiple-dose Study Investigating the Drug-drug Interaction Potential and QTc Effects of Fosmanogepix in Healthy Adult Subjects Fosmanogepix, Placebo, The medicine cocktail (caffeine, bupropion, flurbiprofen, omeprazole, dextromethorphan and midazolam) - Healthy Adult Participants | Phase 1 | Recruiting | Basilea Pharmaceutica | 42 | 2026-10-01 | 2026-10-19 |
| A Trial in Healthy Participants to Assess Drug Interaction Potential of BGB-43395 BGB-43395, Midazolam, Celecoxib - Healthy Adult Participants | Phase 1 | Recruiting | BeOne Medicines | 24 | 2026-09-25 | 2026-10-08 |
| A Phase I Study of the Interaction of D-2570 With Other Drugs in Healthy Adults Itraconazole, Rifampicin, Omeprazole - Healthy Subjects | Phase 1 | Not yet recruiting | InventisBio Co., Ltd | 60 | 2026-09-16 | 2026-10-15 |
| A Study of Single and Multiple Doses of LY5625573 in Healthy Participants, Including Japanese and Chinese Populations, and Participants With Inflammation (High C-Reactive Protein) LY5625573, Midazolam, Placebo - C-Reactive Protein | Phase 1 | Not yet recruiting | Eli Lilly and Company | 96 | 2026-09-01 | 2026-10-09 |
| A Study of Navlimetostat (BMS-986504) Drug Interactions and Food Effect in Healthy Participants Navlimetostat, Itraconazole, Rifampin - Healthy Female Adults | Phase 1 | Recruiting | Bristol-Myers Squibb | 80 | 2026-08-31 | 2026-10-05 |
| A Trial of Lu AH69593 in Healthy Participants Lu AH69593, Itraconazole, Carbamazepine - Healthy Participants | Phase 1 | Recruiting | H. Lundbeck A/S | 46 | 2026-08-27 | 2026-10-14 |
| A Study of LY4355756 in Healthy Participants LY4355756, Midazolam - Healthy | Phase 1 | Recruiting | Eli Lilly and Company | 123 | 2026-08-17 | 2026-10-08 |
| Timing Of Midazolam İn Children Undergoing Adenotonsillectomy: Effects On Stress, Cortisol, And Recovery Midazolam (Oral), Midazolam (Intravenous) - Adenotonsillectomy, Preoperative Anxiety | Not applicable | Not yet recruiting | Erzurum City Hospital | 100 | 2026-08-01 | 2026-06-10 |
| A Drug-Drug Interaction Study Between NTQ5082 Capsules and Midazolam Oral Solutio NTQ5082, Midazolam - Healthy Volunteers, Drug-Drug Interaction (DDI) | Phase 1 | Not yet recruiting | The Third Xiangya Hospital of Central South University | 18 | 2026-07-30 | 2026-08-04 |
| Comparative Assessment of Oral Premedication Regimens in Pediatric Ambulatory Surgery Oral Midazolam Premedication, Oral Midazolam plus Ibuprofen Premedication, Oral Midazolam plus Ketamine Premedication - Pediatric Anesthesia, Premedication | Not applicable | Recruiting | Diskapi Yildirim Beyazit Education and Research Hospital | 135 | 2026-07-26 | 2026-07-28 |
| A Study in Japanese Healthy Men to Test How Well Different Doses of BI 3031185 Are Tolerated and a Study in Japanese Healthy Women to Test Whether BI 3031185 Influences the Amount of a Contraceptive in the Blood BI 3031185, Placebo matching BI 3031185, Midazolam - Healthy | Phase 1 | Terminated | Boehringer Ingelheim | 8 | 2026-07-17 | 2026-10-06 |
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Anxiety Disorders (46) · Pain (29) · Depression (27) · Agnosia (22) · Depressive Disorder, Major (22) · Neoplasms (19) · Pain, Postoperative (19) · Delirium (18) · Emergence Delirium (18) · Depressive Disorder, Treatment-Resistant (13) · Carcinoma, Non-Small-Cell Lung (12) · Critical Illness (12) · Bipolar Disorder (11) · Breast Neoplasms (10) · Diabetes Mellitus, Type 2 (10)
Pfizer (35) · Boehringer Ingelheim (31) · Eli Lilly and Company (25) · AstraZeneca (19) · GlaxoSmithKline (16) · Janssen Research & Development, LLC (15) · Bristol-Myers Squibb (13) · Assiut University (12) · Bayer (11) · Cairo University (10) · Seoul National University Hospital (10) · Hoffmann-La Roche (9) · Yonsei University (9) · Merck Sharp & Dohme LLC (8) · Novartis Pharmaceuticals (8)
United States (387) · China (90) · Germany (62) · Egypt (60) · United Kingdom (53) · South Korea (45) · Belgium (43) · Canada (42) · France (34) · Turkey (Türkiye) (30) · Spain (29) · Netherlands (26) · Brazil (25) · Italy (25) · Israel (20)
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