5050 completed, 1174 unknown, 951 recruiting, 557 not yet recruiting. 6198 Not applicable, 520 Phase 2, 281 Phase 3, 258 Phase 4, 221 Phase 1.
Follow Anxiety Disorders: new trials by email Literature Review of Anxiety Disorders trials Research Report on Anxiety Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Whole-Body Hyperthermia for Mood and Anxiety Disorders Whole-Body Hyperthermia, fMRI - Postpartum Depression, Mood Disorders | Not applicable | Not yet recruiting | Weill Medical College of Cornell University | 240 | 2028-06-01 | 2026-06-23 |
| INNOV5-MH-MAROC: Integrated Mental Health Care for Adolescents and Adults in Primary Care Centers and Schools in Morocco INNOV5 Integrated Mental Health Program, Enhanced Treatment as Usual (TAU+) - Depression in Adolescence, Depression in Adults | Not applicable | Not yet recruiting | Swiss Medical Academy Maroc | 146 | 2028-03-01 | 2025-12-02 |
| Simulation-Based Patient Education to Address Radiotherapy-Related Anxiety in Cancer Patients (ARAISE) Simulation-Based Patient Education - Neoplasms, Anxiety | Not applicable | Not yet recruiting | University Medical Center Goettingen | 144 | 2028-01-01 | 2026-08-11 |
| ACT for Veterans With IBD and Mental Health Challenges Acceptance and Commitment Therapy - Inflammatory Bowel Diseases, Crohn's Disease | Not applicable | Not yet recruiting | VA Office of Research and Development | 50 | 2028-01-01 | 2026-02-09 |
| AI-INFORMED PEER-MENTORING BEHAVIORAL INTERVENTION FOR ANXIETY AND DEPRESSION PRIMARY PREVENTION IN YOUTH Peer-mentoring behavioral intervention, Health Education - Anxiety Depression | Not applicable | Not yet recruiting | University of Patras | 1680 | 2027-09-01 | 2026-04-14 |
| Whole Selves User Testing and Feasibility Study Whole Selves - Alcohol Use, Unspecified, Relationship, Social | Not applicable | Not yet recruiting | Boston University | 107 | 2027-09-01 | 2026-07-28 |
| Mental Health INtervention With Digital APPlications (MIND-APP): Randomized Controlled Researcher Blinded Trial Evaluating the Effectiveness of the Tankevirus and Grubl Mental Health Apps Tankevirus, Grubl, Placebo Application - Anxiety, Depression | Not applicable | Not yet recruiting | University Hospital, Akershus | 1000 | 2027-08-15 | 2026-06-04 |
| Neurobehavioral Investigations of Approach Dynamics in the Ventral Striatum Medtronic Percept RC neurostimulator - Obsessive-Compulsive Disorder (OCD) | Not applicable | Not yet recruiting | Baylor College of Medicine | 12 | 2027-08-01 | 2026-10-01 |
| Virtual Intervention for Behavioral Health in Emerging Adults; "VIBE in the Parks" "VIBE in the Parks", Digital Control - Anxiety, Depression | Not applicable | Not yet recruiting | University of Illinois at Chicago | 268 | 2027-07-01 | 2026-04-23 |
| Video-Guided Jaw Relaxation and Breathing Exercises in Children With Burns Video-Guided Jaw Relaxation, Video-Guided Breathing Exercise - Burn | Not applicable | Not yet recruiting | Izmir Katip Celebi University | 60 | 2027-06-01 | 2026-09-08 |
| The Effect of the Safe and Sound Protocol on Depression and Anxiety Symptoms Safe and Sound Protocol, Control - Anxiety, Depression | Not applicable | Not yet recruiting | HealthPartners Institute | 120 | 2027-06-01 | 2026-10-20 |
| Efficacy of a Personalized, Response-based Transdiagnostic Intervention for Emotional Disorders Delivered Via the Internet: A Protocol for an Adaptive Randomized Controlled Trial UJI Online Transdiagnostic Protocol, UJI On Line Transdiagnostic Hibrid Protocol - Emotional Disorders, Anxiety | Not applicable | Not yet recruiting | Universitat Jaume I | 366 | 2027-05-01 | 2026-05-27 |
| Virtual Reality-based Mindfulness Training for Mental Health After Stroke Virtual-reality hypnotherapy device - Stroke (Subacute) | Not applicable | Not yet recruiting | Nicolas Nicastro | 48 | 2027-04-01 | 2026-05-29 |
| Virtual Communication in the Hospital: Impact on Patients and Surrogates VCHIPS - Communication, Anxiety | Not applicable | Withdrawn | Indiana University | 2027-03-31 | 2026-04-22 | |
| Pivotal U.S. Clinical Validation of AI-COA® for Depression and Anxiety Depression Disorders, Anxiety Disorders | Not yet recruiting | Deliberate Solutions Inc. | 650 | 2027-03-01 | 2025-12-12 | |
| Locating Biomarkers in OCD Through Behavioral Tasks Beads Task, PROVOC Tasks - OCD, Obsessive-Compulsive Disorder | Not yet recruiting | Baylor College of Medicine | 20 | 2027-03-01 | 2026-06-30 | |
| Student-Centred Simulation-Based Skills Training on Coping Self-Efficacy, Stress, and Anxiety Among Nursing Students in the UAE Student-Centred Simulation-Based Skills Training - Perceived Stress, State Anxiety | Not applicable | Not yet recruiting | Universiti Sains Malaysia | 60 | 2027-03-01 | 2026-10-13 |
| A Digital Mindfulness-Based Program for OCD Mindfulness-based cognitive-behavioral therapy digital program - Obsessive-Compulsive Disorder (OCD) | Not applicable | Not yet recruiting | Unidade Local de Saúde de Coimbra, EPE | 128 | 2027-03-01 | 2026-10-13 |
| Multicomponent Pain Self-Management in Adults With Haemophilic Arthropathy Multicomponent pain self-management programme - Hemophilic Arthropathy, Chronic Pain | Not applicable | Not yet recruiting | Investigación en Hemofilia y Fisioterapia | 70 | 2027-03-01 | 2026-10-06 |
| A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus) Glycerol Tributyrate - MELAS Syndrome, Lebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus) | Phase 1 / Phase 2 | Not yet recruiting | George Washington University | 24 | 2027-03-01 | 2026-10-05 |
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Depression (2940) · Pain (931) · Obsessive-Compulsive Disorder (625) · Generalized Anxiety Disorder (509) · Stress Disorders, Post-Traumatic (439) · Psychological Well-Being (397) · Phobia, Social (363) · Kinesiophobia (280) · Sleep Initiation and Maintenance Disorders (277) · Panic Disorder (264) · Depressive Disorder (200) · Neoplasms (195) · Motor Activity (190) · Depressive Disorder, Major (188)
Mental Disorders (8449) · Behavior (3702) · Behavioral Symptoms (3127) · Pathological Conditions, Signs and Symptoms (2216) · Signs and Symptoms (1914) · Neurologic Manifestations (1601) · Nervous System Diseases (1110) · Phobic Disorders (662) · Pathologic Processes (575) · Trauma and Stressor Related Disorders (517) · Stress Disorders, Traumatic (457) · Mood Disorders (455) · Respiratory Tract Diseases (419) · Personal Satisfaction (392)
Cognitive Behavioral Therapy (291) · Therapeutics (148) · Music Therapy (110) · Surveys and Questionnaires (90) · Exercise (85) · Control Groups (79) · Escitalopram (56) · Standard of Care (56) · Mindfulness (53) · Sertraline (53) · Transcranial Magnetic Stimulation (52) · Midazolam (51) · Methods (49) · Acceptance and Commitment Therapy (45) · Paroxetine (44)
Massachusetts General Hospital (101) · Karolinska Institutet (83) · Stanford University (72) · National Institute of Mental Health (NIMH) (66) · University of California, Los Angeles (66) · VA Office of Research and Development (54) · Duke University (49) · University of Pittsburgh (48) · Ataturk University (47) · Saglik Bilimleri Universitesi (47) · New York State Psychiatric Institute (44) · University of Pennsylvania (42) · Yale University (42) · Northwestern University (39) · University of Michigan (39)
United States (2822) · Turkey (Türkiye) (1400) · Canada (471) · France (345) · China (293) · United Kingdom (263) · Spain (257) · Sweden (212) · Germany (172) · Brazil (117) · Taiwan (113) · Italy (111) · Israel (109) · Norway (108) · Denmark (103)
Asle Hoffart, PhD (14) · Gerhard Andersson, PhD (11) · Heather Hadjistavropoulos, PhD (11) · Sverre Urnes Johnson, PhD (11) · Michael Van Ameringen, MD, FRCPC (10) · Yair Bar-Haim, PhD (10) · Heather D Hadjistavropoulos, PhD (8) · Joseph Zohar, MD (8) · Franklin Schneier, MD (7) · Gamze Bozkul (7) · Gerhard Andersson, Professor (7) · Jon E Grant, MD, JD, MPH (7)
PMID 2748771, PMID 34582562, PMID 40243391, PMID 16717171, PMID 21102344, PMID 33319916, PMID 3397865, PMID 35397973, PMID 42743597, PMID 22143997, PMID 22249355, PMID 23945445, PMID 24394383, PMID 24960439, PMID 26969158, PMID 27486544, PMID 29624026, PMID 30027283, PMID 32402261, PMID 32880104, PMID 34693989, PMID 36602886, PMID 37199436, PMID 37795783, PMID 38569683, PMID 38588457, PMID 38767196, PMID 42714910, PMID 42755118, PMID 6226917, PMID 6880820, PMID 10702461, PMID 11556271, PMID 11682427, PMID 12296495, PMID 14399272, PMID 15982444, PMID 15992242, PMID 16367493, PMID 16640481, PMID 17474806, PMID 17559726, PMID 18042300, PMID 18373143, PMID 18615176, PMID 18635722, PMID 18974308, PMID 19578654, PMID 19588390, PMID 19700479
2023 (20), 2019 (12), 2025 (12), 2018 (9), P30CA012197 (5), P50MH122351 (5), 2016 (4), 2017 (4), 1UH3NS100549 (3), 2005 (3), 2009 (3), 2014 (3), P50MH115837 (3), P50MH115838 (3), R01MH045436 (3)