121 recruiting. 121 Phase 2, 21 Phase 3, 16 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 121 | Recruiting 121 |
| Phase 3 | 21 | Recruiting 21 |
| Phase 1 | 16 | Recruiting 16 |
Follow Pain: new trials by email Literature Review of Pain trials Research Report on Pain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A 52-Week Study Evaluating the Efficacy and Safety of Arumakimig (MAS825) in Participants With VEXAS Followed by Open-Label Extension (OLE) Period Arumakimig, Placebo, Oral glucocorticoids - VEXAS Syndrome | Phase 2 | Recruiting | Novartis Pharmaceuticals | 120 | 2026-10-30 | 2026-10-13 |
| A Study of Cebranopadol for Opioid Withdrawal Symptoms in Adults With Chronic Pain Cebranopadol, Placebo - Chronic Pain, Pain | Phase 2 | Recruiting | Adneuris Therapeutics, Inc. | 45 | 2026-10-01 | 2026-10-23 |
| Dexmedetomidine as an Adjuvant to Greater Auricular Nerve Block in Middle Ear Surgeries Bupivacaine, Dexmedetomidine, Normal saline - Postoperative Pain, Middle Ear Surgery | Phase 2 | Recruiting | Minia University | 40 | 2026-09-25 | 2026-10-16 |
| A Study of CYT-1010 in Healthy Volunteers and Participants With Acute Pain After Third Molar Extraction CYT-1010, Placebo - Acute Postoperative Pain, Dental Pain | Phase 1 / Phase 2 | Recruiting | Cytogel Pharma, LLC | 32 | 2026-09-25 | 2026-10-29 |
| Localized Injection of Lidocaine Via the Middle Meningeal Artery for Headache Treatment Lidocaine (drug), Saline - Refractory Migraine, Headache | Phase 2 | Recruiting | Daniel A Tonetti, MD | 80 | 2026-09-09 | 2026-10-01 |
| A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Chronic Low Back Pain LY4065967, Placebo - Chronic Pain, Low Back Pain | Phase 2 | Recruiting | Eli Lilly and Company | 150 | 2026-08-12 | 2026-09-04 |
| Psilocybin to Treat Depression in Spinal Cord Injury Psilocybin (Usona Institute) - Spinal Cord Injury, Depression - Major Depressive Disorder | Phase 1 / Phase 2 | Recruiting | James J. Peters Veterans Affairs Medical Center | 30 | 2026-08-06 | 2026-08-10 |
| A Clinical Trial to Evaluate the Efficacy and Safety of HL-1186 Tablet in the Treatment of Postherpetic Neuralgia HL-1186, HL-1186 placebo, Pregabalin capsule - Postherpetic Neuralgia ( PHN ) | Phase 2 | Recruiting | Shanghai Yidian Pharmaceutical Technology Development Co., Ltd. | 200 | 2026-08-01 | 2026-08-11 |
| Liposomal Bupivacaine vs Standard Bupivacaine for Post-Rhinoplasty Analgesia Standard Bupivacaine, Liposomal Bupivacaine - Pain, Postoperative | Phase 2 | Recruiting | Washington University School of Medicine | 45 | 2026-08-01 | 2026-08-18 |
| Impact of RADA16 Use on Outcomes Following Tonsillectomy in Children RADA16 hydrogel - Postoperative Pain | Phase 2 | Recruiting | Rutgers, The State University of New Jersey | 134 | 2026-07-09 | 2026-07-22 |
| Genicular Artery Embolization for Reducing Pain in Medically Refractory Symptomatic Knee Osteoarthritis Genicular Artery Embolization, Lipiodol, Simple angiogram - Knee Osteoarthritis, Knee Osteoarthritis (Knee OA) | Phase 2 | Recruiting | University of Utah | 40 | 2026-07-01 | 2026-10-30 |
| A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Osteoarthritis Pain LY4065967, Placebo - Osteoarthritis, Knee, Chronic Pain | Phase 2 | Recruiting | Eli Lilly and Company | 150 | 2026-06-25 | 2026-09-04 |
| IA Lidocaine and Methylprednisolone for Headache Associated With Subarachnoid Hemorrhage Lidocaine hydrochloride, Methylprednisolone sodium succinate - Headaches Associated With Subarachnoid Hemorrhage (SAH) | Phase 2 | Recruiting | Daniel Raper, MBBS | 25 | 2026-06-23 | 2026-07-08 |
| Intraperitoneal Irrigation of Ondansteron in Combination With Lidocaine in Acute Postoperative Pain ondansteron - Acue Postoperative Pain | Phase 1 / Phase 2 | Recruiting | Assiut University | 20 | 2026-06-01 | 2026-07-15 |
| Evaluate the Safety and Efficacy of HL-1186 Tablet for Postoperative Analgesia in Abdominal Surgery HL-1186, HL-1186 placebo, Oxycodone-Acetaminophen - Postoperative Pain | Phase 2 / Phase 3 | Recruiting | Shanghai Huilun Pharmaceutical Co., Ltd. | 330 | 2026-05-11 | 2026-07-16 |
| Evaluate the Safety and Efficacy of HL-1186 Tablet for Postoperative Analgesia in Orthopedic Surgery HL-1186, HL-1186 placebo, Oxycodone-Acetaminophen - Postoperative Pain | Phase 2 / Phase 3 | Recruiting | Shanghai Huilun Pharmaceutical Co., Ltd. | 330 | 2026-05-09 | 2026-07-13 |
| Virtual Menstrual Pain Approaches in Females Virtual Auricular Acupressure, Virtual Baduanjin Qigong Exercise, Self Education - Pain (Visceral, Somatic, or Neuropathic), Women of Reproductive Age | Phase 2 / Phase 3 | Recruiting | Nanyang Technological University | 145 | 2026-04-15 | 2026-06-23 |
| Soy Tomato Juice to Improve Outcomes in Pancreatitis Soy-tomato juice product, Will include a soy-tomato juice product to be consumed during the 4 week intervention phase. A total of about 12 ounces (administered in two small cans) of the juice will be consumed - Recurrent Acute Pancreatitis, Chronic Pancreatitis | Phase 1 / Phase 2 | Recruiting | Ohio State University | 35 | 2026-04-02 | 2026-10-20 |
| A Study of LY4515100 in Participants With Pain Following Third Molar Removal LY4515100, Placebo - Acute Pain, Molar | Phase 2 | Recruiting | Eli Lilly and Company | 212 | 2026-04-01 | 2026-05-01 |
| Ketamine Assisted Psychotherapy for Treating Comorbid Chronic Pain and PTSD Ketamine Infusion, Mindfulness-based cognitive therapy - Chronic Pain, Posttraumatic Stress Disorder (PTSD) | Phase 1 / Phase 2 | Recruiting | Dr. Yuliya Knyahnytska | 30 | 2026-03-31 | 2026-09-15 |
Showing 20 of 121. Sign in to see all of them.
Chronic Pain (27) · Pain, Postoperative (27) · Neuralgia (10) · Headache (9) · Depression (7) · Acute Pain (6) · Agnosia (6) · Anxiety Disorders (6) · Opioid-Related Disorders (6) · Arthralgia (5) · Cancer Pain (4) · Low Back Pain (4) · Osteoarthritis (4) · Osteoarthritis, Knee (4)
Neurologic Manifestations (121) · Pathological Conditions, Signs and Symptoms (121) · Signs and Symptoms (121) · Pathologic Processes (39) · Nervous System Diseases (36) · Postoperative Complications (28) · Mental Disorders (23) · Behavior (14) · Neuromuscular Diseases (14) · Musculoskeletal Diseases (13) · Joint Diseases (12) · Peripheral Nervous System Diseases (12) · Central Nervous System Diseases (11) · Brain Diseases (10)
Sodium Chloride (9) · Cannabidiol (5) · Lidocaine (5) · Saline Solution (5) · Dexamethasone (4) · Bupivacaine (3) · Dexmedetomidine (3) · Dronabinol (3) · Ketamine (3) · Pregabalin (3) · Psilocybin (3) · Botulinum Toxins, Type A (2) · Clonidine (2) · Diclofenac (2) · Exercise (2)
Eli Lilly and Company (3) · Massachusetts General Hospital (3) · Rutgers, The State University of New Jersey (3) · Sahiwal medical college sahiwal (3) · Stanford University (3) · University of Maryland, Baltimore (3) · VA Office of Research and Development (3) · Brigham and Women's Hospital (2) · Northwell Health (2) · Shanghai Huilun Pharmaceutical Co., Ltd. (2) · University Health Network, Toronto (2) · University of British Columbia (2) · University of California, Davis (2) · University of California, San Francisco (2) · University of Colorado, Boulder (2)
United States (68) · Canada (14) · China (8) · Pakistan (7) · France (3) · Spain (3) · Denmark (2) · Egypt (2) · Israel (2) · Poland (2) · Puerto Rico (2) · Singapore (2) · Sweden (2) · United Kingdom (2) · Australia (1)
Adeel Riaz, MD (3) · Amber Brooks, MD (1) · Amir Minerbi, MD-PhD (1) · Anthony Mathur (1) · Antoine Roger (1) · Arash Afshari, PhD (1) · Areeba Maryam, BDS (1) · Ari Green, MD, MCR (1) · Asokumar Buvanendran, MD (1) · Bernardino Clavo, MD, PhD (1) · Brett Johnson, MD (1) · Brian Louie, M.D. (1) · Brian Wainger, MD PhD (1) · Bruno Chumpitazi, MD, MPH (1)
PMID 11853818, PMID 12907905, PMID 16400513, PMID 16437520, PMID 17312203, PMID 18844269, PMID 19260079, PMID 21427067, PMID 21575276, PMID 21674151, PMID 23102757, PMID 23549581, PMID 24550805, PMID 24687190, PMID 24733808, PMID 25699252, PMID 27578767, PMID 28409480, PMID 28704354, PMID 28990015, PMID 29577509, PMID 29764303, PMID 31779159, PMID 32371500, PMID 32379556, PMID 32633773, PMID 33134600, PMID 33738491, PMID 34867525, PMID 35001856, PMID 36044208, PMID 36048469, PMID 36357803, PMID 36532184, PMID 36619264, PMID 36798353, PMID 38528704, PMID 38862073, PMID 38951902, PMID 39138719, PMID 39260823, PMID 39979051, PMID 40192825, PMID 41831719, PMID 42267534
2023 (2), 1RM1NS128741-01 (1), 2019 (1), I01RX004287 (1), IK2CX002646-01A2 (1), P01NS119159 (1), P30AG022845 (1), R01AG082777 (1), R01AT011341 (1), R01AT013240 (1), R01DA056045 (1), R01DA058620 (1), R01DA060066 (1), R01DK138871 (1), R21AR082123 (1)