19033 completed, 6035 unknown, 5168 recruiting, 2329 terminated. 15715 Not applicable, 4970 Phase 2, 3144 Phase 1, 2939 Phase 3, 1622 Phase 4.
Follow Brain Diseases: new trials by email Literature Review of Brain Diseases trials Research Report on Brain Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Observational Study to Assess Migraine Prediction Tool Daily questionnaire - Migraine | Suspended | Theranica | 200 | 2030-01-01 | 2024-11-22 | |
| Tau Pathology in the Brain After Hip or Knee Replacement Surgery Hip or Knee Arthroplasty Under Spinal Anesthesia - Postoperative Cognitive Dysfunction, Alzheimer Disease | Recruiting | Uppsala University Hospital | 30 | 2029-04-01 | 2026-10-15 | |
| A Study Using Brain Stimulation and Behavioral Therapy to Increase Extent of Resection in Low-Grade Gliomas RNS System Implantation - Glioma, Glioma Intracranial | Not applicable | Not yet recruiting | Medical College of Wisconsin | 3 | 2028-08-01 | 2026-10-13 |
| The Effect of Sympathetic Modulation on Cerebral Vasospasm Secondary to Aneurysmal Subarachnoid Hemorrhage Vectris trial leads and stimulation, Sham - Vasospasm, Cerebral, Aneurysmal Subarachnoid Hemorrhage | Not applicable | Suspended | University of Alabama at Birmingham | 25 | 2028-07-31 | 2026-09-24 |
| Terazosin And Metabolic Energetics in Parkinson's Disease Terazosin 5 MG, Placebo - Parkinson's Disease (PD) | Phase 2 | Suspended | Ergun Y. Uc | 120 | 2028-07-01 | 2026-10-09 |
| Phase 1/2 Study Evaluating the Safety, PK/PD, and Clinical Activity of Oral JBI-778 in Patients With Brain Metastases, Leptomeningeal Disease, or Recurrent High Grade Glioma JBI-778 - Brain Metastases From Solid Tumors, Leptomeningeal Disease | Phase 1 / Phase 2 | Not yet recruiting | Jubilant Therapeutics Inc. | 113 | 2028-04-01 | 2026-08-07 |
| Smartphone App for Adolescents With Idiopathic Scoliosis DinSkoliose smartphone application - Adolescence Idiopathic Scoliosis, AIS | Not applicable | Not yet recruiting | Oslo Metropolitan University | 30 | 2028-04-01 | 2026-07-07 |
| EMBRACE Study: Enduring Migraine Benefit From Responsive Artery Coil Embolization TEMMA Endovascular Treatment - Migraine Disorders, Refractory Migraine | Not applicable | Withdrawn | Cortex Neurovascular | 2028-03-01 | 2026-10-27 | |
| Using Power Mobility Training to Promote Arm & Hand Function in Children With Cerebral Palsy Arm- and hand-use focused power mobility training - Cerebral Palsy, Hemiplegia, Infantile | Not applicable | Not yet recruiting | Grand Valley State University | 10 | 2028-01-19 | 2026-09-11 |
| Sodium Lactate in Severe TBI Sodium Lactate, placebo - Traumatic Brain Injury | Phase 2 | Not yet recruiting | University of California, Los Angeles | 264 | 2028-01-10 | 2026-01-16 |
| Safety and Outcomes of MUSE Stem Cell Therapy in Individuals With Traumatic Brain Injury MUSE Stem Cell Therapy - Traumatic Brain Injury, Traumatic Brain Injury (TBI) Patients | Not yet recruiting | Healing Hope International | 10 | 2028-01-01 | 2026-03-10 | |
| Double-Blind Clinical Trial of Subthalamic Nucleus Deep Brain Stimulation in Early-Stage Parkinson's Disease active subthalamic nucleus deep brain stimulation plus optimal drug therapy, inactive subthalamic nucleus deep brain stimulation plus optimal drug therapy - Parkinson Disease | Not applicable | Not yet recruiting | Mallory Hacker | 40 | 2028-01-01 | 2026-02-20 |
| To Evaluate the Safety and Efficacy of GS1168 Injection in Adult Phenylketonuria GS1168 injection - Phenylketonuria (PKU) | Early Phase 1 | Not yet recruiting | Gritgen Therapeutics Co., Ltd. | 9 | 2027-12-31 | 2026-09-10 |
| Essential Acute Stroke Care in Low Resource Settings: a Pilot studY Acute stroke care Intervention arm - Acute Stroke | Not applicable | Not yet recruiting | The George Institute | 300 | 2027-12-30 | 2026-06-11 |
| Study to Evaluate the Safety, Tolerability, Efficacy, and PK of FHL-301 in Parkinson's Disease Patients. Gemfibrozil, Placebo - Parkinson Disease | Phase 2 | Withdrawn | Forest Hills Lab | 2027-11-01 | 2026-08-19 | |
| Transcranial Magnetic Stimulation for Alzheimer's Disease Treatment Active Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation - Alzheimer Disease | Not applicable | Not yet recruiting | Universitat Oberta de Catalunya | 45 | 2027-11-01 | 2026-07-21 |
| The Mechatronic Remote Physiotherapy System (MRPS) in Remote Stroke Rehabilitation Mechatronic Remote Physiotherapy System (MRPS), Early Supported Discharge - Stroke, Neurological Disorder | Not applicable | Not yet recruiting | Institute of Technology, Sligo | 14 | 2027-11-01 | 2026-11-04 |
| REstoring Flow by REvascularization With Submaximal Angioplasty in Hemodynamic IntraCranial Atherosclerotic Stenosis Submaximal balloon angioplasty - Intracranial Atherosclerotic Disease, Stroke | Not applicable | Not yet recruiting | Case Western Reserve University | 159 | 2027-10-01 | 2025-11-04 |
| Terazosin for Dementia With Lewy Bodies Terazosin Hydrochloride, Placebo - Dementia With Lewy Bodies | Phase 1 / Phase 2 | Not yet recruiting | Qiang Zhang | 40 | 2027-10-01 | 2026-03-12 |
| Behavior Therapy vs Education for Persistent Headache After Mild TBI Headache reprocessing, Headache education - Post-Traumatic Headache | Not applicable | Not yet recruiting | VA Office of Research and Development | 60 | 2027-10-01 | 2025-12-26 |
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Riphah International University (353) · Assistance Publique - Hôpitaux de Paris (278) · National Institute of Neurological Disorders and Stroke (NINDS) (278) · VA Office of Research and Development (257) · Beijing Tiantan Hospital (240) · Pfizer (217) · National Taiwan University Hospital (210) · Mayo Clinic (197) · Chang Gung Memorial Hospital (190) · Duke University (188) · Johns Hopkins University (179) · Xuanwu Hospital, Beijing (178) · Cairo University (177) · Hospices Civils de Lyon (171) · Assiut University (169)
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