1116 completed, 184 recruiting, 134 unknown, 118 terminated. 779 Not applicable, 361 Phase 2, 162 Phase 1, 118 Phase 4, 98 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Digital Tools to Engage and Activate Patients During Hospitalization Passive Digital Tools, Active Digital Tools - Hospital Information Systems | Not applicable | Not yet recruiting | Brigham and Women's Hospital | 520 | 2028-07-01 | 2026-09-08 |
| Dynamic Treatment Regimes for Opioid Use Disorder Medication for opioid use disorder, psychotherapy - Opioid Use Disorder | Phase 2 | Not yet recruiting | Brigham and Women's Hospital | 75 | 2028-07-01 | 2025-11-04 |
| Mindfulness Therapy for Chronic Pain After Intimate Partner Violence Mindfulness-Based Cognitive Therapy for Trauma-Informed Pain (MBCT-TIP), Health Enhancement Program (HEP) - Chronic Pain | Not applicable | Not yet recruiting | Brigham and Women's Hospital | 58 | 2027-07-01 | 2026-07-14 |
| Tirzepatide for the Treatment of Cannabis Use Disorder Tirzepatide, Placebo - Cannabis Use Disorder | Phase 2 | Not yet recruiting | Brigham and Women's Hospital | 6 | 2027-03-01 | 2026-10-09 |
| The Variable Ventilation Trial (Part A) Variable Ventilation, Conventional Ventilation - ARDS (Acute Respiratory Distress Syndrome) | Not applicable | Not yet recruiting | Brigham and Women's Hospital | 20 | 2027-02-01 | 2026-08-27 |
| Antihypertensive Self-titration in US Primary Care Self-Titration - Hypertension | Not applicable | Not yet recruiting | Brigham and Women's Hospital | 30 | 2027-02-01 | 2026-10-13 |
| Semaglutide for the Treatment of Cannabis Use Disorder semaglutide - Cannabis Use Disorder, Cue-reactivity | Phase 2 | Not yet recruiting | Massachusetts General Hospital | 40 | 2027-01-10 | 2026-10-19 |
| WELL-MPN: A Digital Lifestyle App for Patients With MPNs WELL-MPN Digital App - Myeloproliferative Neoplasms (MPNs) | Not applicable | Not yet recruiting | Brigham and Women's Hospital | 75 | 2027-01-01 | 2026-09-29 |
| Randomized Trial of a Sleep Disorders Program on Firefighter Safety and Disability ... Sleep Health Education Program (SHEP) - Sleep Disorder | Not applicable | Not yet recruiting | Brigham and Women's Hospital | 2400 | 2027-01-01 | 2026-10-13 |
| Strategies to Decentralize Breast Ultrasound in Rwanda Teleultrasound with Philips Lumify ultrasound probes and Reacts software, Asynchronous virtual feedback - Breast Cancer, Early Detection of Cancer | Not applicable | Not yet recruiting | Brigham and Women's Hospital | 1792 | 2027-01-01 | 2026-06-02 |
| Augmented Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for PE Ultrasound-facilitated, catheter-directed lower-dose fibrinolysis, Tissue Plasminogen Activator - Pulmonary Embolism, Right Ventricular Dysfunction | Suspended | Brigham and Women's Hospital | 60 | 2027-01-01 | 2026-01-21 | |
| Metabolomics-Driven Insights Into Ultra-Processed Foods UPF Test Diet A: Starchy, refined grains, UPF Test Diet B: Meat, fish, and bread products, UPF Diet C: Dairy products, including cheese and cream - Diet, Food and Nutrition | Not applicable | Not yet recruiting | Brigham and Women's Hospital | 40 | 2027-01-01 | 2026-07-21 |
| Biophysical Assessments of Acupuncture Points in Inflammatory Bowel Disease Inflammatory Bowel Disease (IBD) | Not yet recruiting | Brigham and Women's Hospital | 100 | 2027-01-01 | 2026-10-20 | |
| Computerized Decision Support to Prevent Stroke in Atrial Fibrillation Alert-based computerized decision support - Atrial Fibrillation, Stroke | Not applicable | Not yet recruiting | Brigham and Women's Hospital | 2500 | 2026-12-30 | 2026-02-25 |
| Repurposing a Combination Antiretroviral Drug Therapy to Target Retrotransposons and Treat Early Alzheimer's Disease Emtricitabine and tenofovir disoproxil fumarate combination, Placebo - Alzheimer's Disease | Phase 1 | Not yet recruiting | Brigham and Women's Hospital | 20 | 2026-12-01 | 2026-08-31 |
| AI Chatbot for Prostate Radiation Therapy Patient Education AI Educational Chatbot - Prostate Cancer Patients | Not applicable | Not yet recruiting | Brigham and Women's Hospital | 50 | 2026-12-01 | 2026-09-17 |
| A Structured Peer Support Intervention for Patients Undergoing Hematopoietic Stem Cell Transplantation STEPP, Minimally Enhanced Usual Care Control - Hematopoietic Stem Cell Transplantation | Not applicable | Not yet recruiting | Brigham and Women's Hospital | 350 | 2026-12-01 | 2026-09-10 |
| Alpha Down Electroencephalography (EEG) Neurofeedback for Alcohol Use Disorder: Feasibility Trial EEG Neurofeedback - Alcohol Use Disorder (AUD) | Not applicable | Not yet recruiting | Brigham and Women's Hospital | 10 | 2026-12-01 | 2026-10-01 |
| Acute Hospital Care at Home for People Living With Dementia Acute hospital care at home, Standard medical treatment - Emergency Department Visit, Home Care Services | Not applicable | Not yet recruiting | Brigham and Women's Hospital | 200 | 2026-11-17 | 2026-10-16 |
| Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder Psilocybin - Alcohol Use Disorder | Phase 2 | Not yet recruiting | Brigham and Women's Hospital | 36 | 2026-11-15 | 2026-10-09 |
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Hypertension (60) · Breast Neoplasms (56) · Obesity (55) · Diabetes Mellitus (52) · Cardiovascular Diseases (51) · Heart Failure (50) · Diabetes Mellitus, Type 2 (49) · Asthma (46) · Sleep Apnea, Obstructive (46) · Prostatic Neoplasms (32) · Arthritis, Rheumatoid (31) · Pulmonary Disease, Chronic Obstructive (31) · Pain (30) · Depression (29) · Atrial Fibrillation (27)
Bevacizumab (27) · Cisplatin (26) · Cholecalciferol (24) · Fish Oils (23) · Fatty Acids, Omega-3 (19) · Docetaxel (16) · Methotrexate (14) · Paclitaxel (14) · Saline Solution (14) · Transcranial Magnetic Stimulation (14) · semaglutide (14) · Carboplatin (12) · Eplerenone (12) · Fluorouracil (12) · Bortezomib (11)
United States (1620) · Canada (30) · South Africa (13) · United Kingdom (13) · Germany (11) · India (10) · Rwanda (9) · Australia (8) · Haiti (7) · Italy (7) · Botswana (6) · China (6) · Denmark (6) · Netherlands (6) · Puerto Rico (6)
Shirley Wang, PhD, ScM (55) · Madhav Thambisetty, MD, PhD (14) · Niteesh K Choudhry, MD, PhD (11) · Elliot Israel, MD (9) · Mark A Creager, MD (9) · Elizabeth B Klerman, MD PhD (8) · Jeffrey L Schnipper, MD, MPH (8) · Scott A Sands, PhD (8) · Gail K Adler, MD, PhD (7) · Jeremy M Wolfe, PhD (7) · Samuel Z. Goldhaber, MD (7) · Gregory Piazza, MD, MS (6) · Matthew Kulke, MD (6) · Shalender Bhasin, MD (6)
PMID 33327727, PMID 42268612, PMID 24191286, PMID 33513226, PMID 34853363, PMID 38244989, PMID 39688178, PMID 40886075, PMID 41207920, PMID 19139178, PMID 26791187, PMID 27923400, PMID 28931532, PMID 29526608, PMID 29531764, PMID 31254057, PMID 31271875, PMID 31699704, PMID 32492153, PMID 32749491, PMID 33201236, PMID 33586138, PMID 33724323, PMID 34039021, PMID 34543425, PMID 34932079, PMID 35082139, PMID 35482127, PMID 36285795, PMID 37212116, PMID 37267732, PMID 37454148, PMID 37952113, PMID 38272846, PMID 39888728, PMID 41159585, PMID 42389777, PMID 10752330, PMID 10768086, PMID 10903223, PMID 11068116, PMID 11112130, PMID 11374664, PMID 11690728, PMID 11875138, PMID 11914989, PMID 12351295, PMID 12490682, PMID 12623025, PMID 12707140
P30AG064199 (14), P60AR047782 (5), R01HL102321 (5), K24HL103845 (3), R01EY017001 (3), R01HL140574 (3), K23AG030967 (2), K23DA042326 (2), K23MH120324 (2), M01RR002635 (2), P01AG009975 (2), P01CA021239 (2), P01HL095491 (2), P30AG031679 (2), P30CA006516 (2)