81 withdrawn. 81 Phase 3, 12 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 81 | Withdrawn 81 |
| Phase 2 | 12 | Withdrawn 12 |
Follow Pain: new trials by email Literature Review of Pain trials Research Report on Pain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Ultrasound-Guided Dextrose Prolotherapy in Ehlers-Danlos Syndrome Patients Dextrose 50% Intravenous Solution, Lidocaine 1% Injectable Solution - Ehlers-Danlos Syndrome, Low Back Pain | Phase 3 | Withdrawn | Tulane University | 2026-10-05 | 2026-10-08 | |
| Efficacy and Safety of the N0750 Compared to Monotherapies in the Treatment of Painful Diabetic Peripheral Neuropathy N0750, Cymbalta®, Lyrica® - Painful Diabetic Peripheral Neuropathy (PDPN) | Phase 3 | Withdrawn | Eurofarma Laboratorios S.A. | 2026-04-01 | 2025-12-18 | |
| Intracervical Balloon Placement With Nitrous Oxide Administration Nitrous oxide, Oxygen - Labor Pain, Induced; Birth | Phase 3 | Withdrawn | Jefferson Drapkin | 2026-03-01 | 2026-09-17 | |
| Rifaximin for Treatment of Bloating in Children and Adults With Cystic Fibrosis Rifaximin 550 MG Oral Tablet [XIFAXAN], Placebo - Cystic Fibrosis, Abdominal Pain | Phase 2 / Phase 3 | Withdrawn | Wake Forest University Health Sciences | 2025-07-01 | 2025-06-27 | |
| Efficacy of Transversus Abdominis Plane Block for Laparoscopic Cholecystectomy Abdominal Wall Block, Surgical infiltration, Sterile saline - Pain, Postoperative | Phase 3 | Withdrawn | Boston Children's Hospital | 2024-03-01 | 2024-07-08 | |
| TreatMent Of Knee osTeoarthritis wIth chONdroitin Sulfate - the OA MOTION Study Chondroitin Sulfate Sodium, Placebo - Knee Osteoarthritis | Phase 3 | Withdrawn | IBSA Institut Biochimique SA | 2023-12-01 | 2023-10-05 | |
| Diclofenac Gel in the Treatment of Cervicogenic Headache Diclofenac 1% Topical, Petroleum Jelly - Cervicogenic Headache | Phase 3 | Withdrawn | Loma Linda University | 2023-12-01 | 2025-01-23 | |
| A Study to Evaluate the Efficacy and Safety of X0002 Spray in Subjects With Osteoarthritis of the Lumbar Spine X0002 - Osteoarthritis of the Lumbar Spine, Pain, Back | Phase 3 | Withdrawn | Techfields Pharma Co. Ltd | 2023-03-30 | 2023-06-12 | |
| Investigating RELEARN Neurofeedback as Treatment for Chronic Musculoskeletal Pain RELEARN Neurofeedback, Standard care control - Chronic Knee Pain, Chronic Pain | Phase 2 / Phase 3 | Withdrawn | Redo-Neurosystems | 2022-10-05 | 2024-02-06 | |
| Methadone for 'Adenocarcinopathic' Pain Treatment Methadone, Morphine - Cancer Pain, Adenocarcinoma | Phase 3 | Withdrawn | Ottawa Hospital Research Institute | 2022-09-01 | 2022-12-05 | |
| Opioid-Free Pain Control Regiment Following Robotic Radical Prostatectomy Tramadol, Gabapentin, Hydrocodone-Acetaminophen - Radical Prostatectomies | Phase 2 / Phase 3 | Withdrawn | Wake Forest University Health Sciences | 2022-08-01 | 2022-09-06 | |
| Topical CBD for Musculoskeletal Pain CBD, Control - Musculoskeletal Pain | Phase 2 / Phase 3 | Withdrawn | University of Virginia | 2022-01-01 | 2024-02-28 | |
| Topical Morphine for Analgesia in Patients With Skin Grafts Placebo, Morphine - .25 mg, Morphine - Skin Transplantation, Pain | Phase 3 | Withdrawn | Rambam Health Care Campus | 2022-01-01 | 2022-05-03 | |
| Intraabdominal Chloroprocaine During Cesarean Delivery for Pain Control Chloroprocaine Hcl 2% Inj, Normal saline - Cesarean Section Complications, Pain | Phase 3 | Withdrawn | Johns Hopkins University | 2021-06-01 | 2021-09-29 | |
| Phase 3 Study to Assess Resiniferatoxin vs Standard of Care for the Treatment of Intractable Cancer Pain Resiniferatoxin, Standard of Care - Pain, Intractable, Pain Cancer | Phase 3 | Withdrawn | Sorrento Therapeutics, Inc. | 2020-12-01 | 2021-11-09 | |
| Lidocaine-Prilocaine Cream in Conjunction With Paracervical Block for Pain With Abortion Lidocaine-Prilocaine Cream, Placebo Cream, 1% Lidocaine Paracervical Block - Pain | Phase 3 | Withdrawn | Stanford University | 2020-12-01 | 2018-05-16 | |
| Cefaliv® Compared to Neosaldina® in the Treatment of Migraine Attacks Cefaliv® & Placebo, Neosaldina® & Placebo - Migraine Headache | Phase 3 | Withdrawn | Ache Laboratorios Farmaceuticos S.A. | 2020-10-01 | 2019-04-10 | |
| The Efficacy and Safety of 3% Cannabidiol (CBD) Cream in Patients With Epidermolysis Bullosa: A Phase II/III Trial AVCN583601 (3% Cannabidiol cream) - Epidermolysis Bullosa, Pain | Phase 2 / Phase 3 | Withdrawn | Elena Pope | 2020-08-01 | 2021-06-18 | |
| Preemptive Acetaminophen for Postoperative Pain Control Following Minimally Invasive Hysterectomy Acetaminophen, Placebo - Post Operative Pain | Phase 2 / Phase 3 | Withdrawn | Montefiore Medical Center | 2020-05-06 | 2022-08-18 | |
| Investigational Use of Erenumab for the Treatment of Fibromyalgia Pain Erenumab, Saline - Fibromyalgia | Phase 3 | Withdrawn | United States Naval Medical Center, Portsmouth | 2020-02-26 | 2025-08-14 |
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Pain, Postoperative (13) · Chronic Pain (8) · Headache (8) · Agnosia (7) · Migraine Disorders (6) · Low Back Pain (5) · Acute Pain (4) · Labor Pain (4) · Neoplasms (4) · Neuralgia (4) · Osteoarthritis (4) · Back Pain (3) · Abdominal Pain (2) · Cancer Pain (2)
Neurologic Manifestations (81) · Pathological Conditions, Signs and Symptoms (81) · Signs and Symptoms (81) · Nervous System Diseases (25) · Pathologic Processes (18) · Postoperative Complications (14) · Brain Diseases (9) · Central Nervous System Diseases (9) · Musculoskeletal Diseases (9) · Headache Disorders (8) · Neurobehavioral Manifestations (8) · Perceptual Disorders (8) · Headache Disorders, Primary (7) · Joint Diseases (7)
Acetaminophen (5) · Ketamine (5) · Ropivacaine (5) · Bupivacaine (4) · Saline Solution (4) · Dexamethasone (3) · Gabapentin (3) · Morphine (3) · Pregabalin (3) · Sodium Chloride (3) · Caffeine (2) · Calcium Dobesilate (2) · Fentanyl (2) · Ketoprofen (2) · Ketorolac (2)
Ache Laboratorios Farmaceuticos S.A. (4) · Imprimis Pharmaceuticals, Inc. (2) · Loma Linda University (2) · University of Alabama at Birmingham (2) · Wake Forest University Health Sciences (2) · 9305-9954 Quebec Inc (1) · Alliance for Clinical Trials in Oncology (1) · Allodynic Therapeutics, Inc (1) · Alza Corporation, DE, USA (1) · Bayer (1) · BioDelivery Sciences International (1) · Boston Children's Hospital (1) · Brigham and Women's Hospital (1) · Carilion Clinic (1) · Centre Hospitalier Universitaire de la Réunion (1)
United States (31) · Brazil (5) · Canada (5) · France (2) · Israel (2) · Belgium (1) · Chile (1) · Denmark (1) · Norway (1) · South Korea (1) · Spain (1)
Ahizechukwu Eke, MD MPH (1) · Andrew Finn, PharmD (1) · Baha Moshiree, MD (1) · Brent DeGeorge, MD, PhD (1) · Bruno Gagnon, MD MSc (1) · Cheryl Hartzell, MD (1) · Christopher A Godlewski, MD (1) · Christopher Godlewski, MD (1) · Claudia Palmeira, MD, PhD (1) · Daniel Bunout, MD (1) · David Kushner (1)
PMID 11130605, PMID 18242337, PMID 21167790, PMID 23388191, PMID 23392233, PMID 24666860, PMID 39428602, PMID 8867249, PMID 9121819
2019 (2), 2015 (1), K23NS050485 (1), P30CA014089 (1), U10CA037429 (1), U10CA101165 (1)