35 completed, 26 unknown, 9 terminated, 7 recruiting. 58 Not applicable, 11 Phase 4, 6 Phase 2, 3 Early Phase 1, 2 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Wide-Awake Local Anesthesia No-Tourniquet (WALANT) Procedures Preoperative WALANT Educational Video, Traditional Preoperative Counseling - Hand Injuries and Disorders | Not applicable | Not yet recruiting | Carilion Clinic | 100 | 2026-10-01 | 2026-09-22 |
| Inflammation and Medical Provider Attitudes, Cognition, and Treatment Decisions Study Influenza vaccine, Placebo - Decision-Making, Patient Care | Phase 2 | Recruiting | University of Arkansas, Fayetteville | 210 | 2026-09-01 | 2026-09-30 |
| MoDi Twin Placental Imaging Verasonics Vantage 256 Ultrasound - Monochorionic Diamniotic Placenta, Monochorial Monoamniotic Placenta | Not applicable | Not yet recruiting | Carilion Clinic | 10 | 2026-07-01 | 2026-06-25 |
| Pectoral Block in Breast Reduction for Pain Control Pectoral II Nerve Block, Post Operative Pain Relievers - Macromastia (Symptomatic) | Phase 4 | Recruiting | Carilion Clinic | 80 | 2026-04-01 | 2026-04-14 |
| Efficacy of a Topical Palmitated Formulation of Capsaicin (Capsadyn®) In the Treatment of Diabetic Neuropathic Foot Pain Capsaicin Palmitate, Placebo - Diabetic Neuropathies, Painful, Diabetic Foot | Early Phase 1 | Recruiting | Carilion Clinic | 80 | 2025-11-26 | 2026-04-20 |
| Low-Intensity Focused Ultrasound Neuromodulation for Epilepsy Low-intensity Focused Ultrasound, Sham - Epilepsy (Treatment Refractory), Epilepsy Comorbidities | Not applicable | Enrolling by invitation | Carilion Clinic | 6 | 2025-10-13 | 2026-01-21 |
| Placental Imaging Techniques ultrafast power Doppler imaging (uPDI) / quantitative ultrasound (QUS) - Fetal Growth Restriction (FGR), Placental Insufficiency | Not applicable | Recruiting | Carilion Clinic | 60 | 2025-04-23 | 2026-05-22 |
| Clinical Comparison of Flow Regulated Nasal Oxygen Delivery System (FRNDS) Cannula and Plethysmography Belts Flow-regulated nasal oxygen delivery system (FRNDS) - Respiratory Failure With Hypoxia | Not applicable | Completed | Virginia Polytechnic Institute and State University | 57 | 2025-04-01 | 2025-09-09 |
| A Novel, Low-Cost, Handheld 3D Imaging System for Improved Screening for Cervical Neoplasia in Resource-Limited Settings CervImage device - Cervical Intraepithelial Neoplasia | Not applicable | Active not recruiting | Carilion Clinic | 18 | 2025-01-16 | 2026-03-18 |
| Effectiveness of Adding Morphine to Intraosseous Vancomycin for Pain Control in Total Knee Arthroplasty Morphine, Vancomycin - Primary Total Knee Arthroplasty, Intraosseous Morphine Injection | Phase 2 | Completed | Carilion Clinic | 100 | 2024-12-01 | 2025-09-10 |
| The BH-Works Suicide Prevention Program for Sexual and Gender Minority Youth The Behavioral Health-Works Suicide Prevention Program for Sexual and Gender Minority Youth - Suicide, Engagement, Patient | Not applicable | Terminated | Virginia Polytechnic Institute and State University | 18 | 2024-07-24 | 2026-04-27 |
| 3D Printed Personalized Ostomy Appliance 3D Printed Personalized Ostomy Appliance - 3D Printing, Ostomy | Not applicable | Recruiting | Carilion Clinic | 30 | 2024-05-10 | 2025-01-22 |
| Clinical Evaluation of a Device for Treatment of Lymphedema of the Upper Extremity LymphaVibe - Lymphedema, Lymphedema Arm | Not applicable | Completed | Carilion Clinic | 15 | 2024-05-01 | 2026-01-21 |
| Theta Burst TMS for Treatment of Methamphetamine Use Disorder Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation - Methamphetamine Abuse | Not applicable | Unknown | Carilion Clinic | 40 | 2023-12-20 | 2024-04-26 |
| Evaluating Adenoma Recurrence After Endoscopic Mucosal Resection With Margin Marking or Post Treatment With Snare Tip Soft Coagulation Adenoma Colon Polyp | Recruiting | AdventHealth | 342 | 2023-12-08 | 2026-01-05 | |
| Measurement-Based Care (MBC) Implementation, Effectiveness, and Mechanisms of Change Psychotherapy - Depressive Disorder, Anxiety Disorders | Not applicable | Active not recruiting | Carilion Clinic | 89 | 2023-10-10 | 2026-06-29 |
| Decreasing the Temporal Window in Individuals With Alcohol Use Disorder Scarcity Narrative, Neutral Narrative - Alcohol Use Disorder | Not applicable | Completed | Virginia Polytechnic Institute and State University | 124 | 2023-09-21 | 2025-12-17 |
| Mobile Cardiac Outpatient Telemetry for Unexplained Syncope Mobile Cardiac Outpatient Telemetry Device (MCOT) - Syncope, Arrhythmia | Not applicable | Unknown | Carilion Clinic | 160 | 2023-09-01 | 2023-07-24 |
| Patient Education Video to Reduce OTC NSAIDs Educational video - Chronic Kidney Diseases, Heart Failure | Not applicable | Unknown | Carilion Clinic | 1452 | 2023-08-02 | 2024-09-03 |
| Low-Intensity Focused Ultrasound For Insular Neuromodulation in Chronic Pain Low-intensity Focused Ultrasound (LIFU), Sham Low-intensity focused ultrasound (LIFU) - Fibromyalgia, Complex Regional Pain Syndromes | Not applicable | Unknown | Carilion Clinic | 27 | 2023-07-15 | 2023-10-16 |
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Pain, Postoperative (5) · Patient Satisfaction (4) · Osteoarthritis, Knee (3) · Alcoholism (2) · Aphasia (2) · Back Pain (2) · Brain Injuries, Traumatic (2) · Chronic Pain (2) · Crohn Disease (2) · Diabetes Mellitus, Type 2 (2) · Endometrial Neoplasms (2) · Epilepsy (2) · Obesity (2) · Pain (2) · Rotator Cuff Injuries (2)
Sodium Chloride (3) · Bupivacaine (2) · Ketamine (2) · Methods (2) · Saline Solution (2) · Acetaminophen (1) · Acetylcysteine (1) · Analgesics, Non-Narcotic (1) · Anesthesia, General (1) · Blood Flow Restriction Therapy (1) · Blood Glucose Self-Monitoring (1) · Capsaicin (1) · Capsule Endoscopy (1) · Carboplatin (1) · Cephalexin (1)
United States (84) · Canada (1)
Cassandra Mierisch, MD (3) · Peter J Apel, MD, PhD (3) · Aashit Shah, MD (2) · Dennis R Scribner, JR, MD (2) · Jeff S Stein, PhD (2) · John W Epling, MD (2) · Mariana Phillips, MD (2) · Megan D Whitham, MD (2) · Rahul Pandey, MD (2) · Stephen M LaConte, PhD (2) · Thomas K Miller, MD (2) · Virginia O'Brien, MD (2) · Aiguo Han, PhD (1) · Anthony Capito, MD (1) · Azziza Bankole, MD (1)
PMID 16151035, PMID 20413741, PMID 24612000, PMID 25574078, PMID 25784587, PMID 26855535, PMID 27660341, PMID 28158501, PMID 29547484, PMID 30155744, PMID 30362878, PMID 31730554, PMID 31834165, PMID 31884902, PMID 34323542, PMID 34888414, PMID 36343674, PMID 36908422, PMID 36971688, PMID 37474181, PMID 38261785
UL1TR003015 (3), R01AA027381 (2), R01MD019051 (1), R18DK091811 (1), R21HD095027 (1), R21NR018349 (1), R44CA254586 (1)