1898 completed, 189 terminated, 89 recruiting, 64 active not recruiting. 529 Phase 2, 478 Phase 1, 411 Phase 3, 187 Phase 4, 183 Not applicable.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Observe the Pattern of Use and Safety of Rivaroxaban in Children Under 2 Years Old With Venous Thromboembolism (VTE) Rivaroxaban (Xarelto, BAY59-7939), Standard of care (SOC) - Venous Thromboembolism, Children Under 2 Years | Not yet recruiting | Bayer | 850 | 2027-09-01 | 2026-10-02 | |
| Post Approval Phase 4 Study to Learn More About How Safe Octocog Alfa is, and How Well it Works in Patients With Severe Hemophilia A in India Octocog alfa - Severe Hemophilia A | Not yet recruiting | Bayer | 30 | 2027-04-05 | 2026-10-21 | |
| A Study of AB-1005 Gene Therapy in Japanese Adults With Moderate Parkinson's Disease (J-REGENERATE-PD) AB-1005 - Parkinson Disease | Phase 2 | Not yet recruiting | Bayer | 8 | 2027-01-25 | 2026-07-29 |
| A Study to Learn About How Safe Nitroglycerin is and How it Affects the Body When Taken Along With Nurandociguat in People With Coronary Artery Disease Nitroglycerin spray, Nurandociguat, Placebo - Stable Coronary Artery Disease | Phase 1 | Not yet recruiting | Bayer | 36 | 2027-01-01 | 2026-10-06 |
| An Observational Pregnancy Safety Study in Women Who Were Exposed to the Drug Nifurtimox During Pregnancy to Learn About the Risk of Pregnancy Complications and About the Mother's and Baby's Health Nifurtimox (BAYA2502) - Chagas Disease | Not yet recruiting | Bayer | 50 | 2026-12-31 | 2026-07-06 | |
| Prospective Trial of the Efficacy and Safety of a Personalized Regimen of High-dose Aflibercept 8mg on Treatment-naive Polypoidal Choroidal Vasculopathy: the PALLAS Trial aflibercept 8 mg - Polypoidal Choroidal Vasculopathy, Polypoidal Choroidal Vasculopathy (PCV) | Phase 3 | Recruiting | Yeungnam University College of Medicine | 50 | 2026-12-24 | 2026-02-05 |
| An Observational Study to Learn More About How Elinzanetant is Used and How Well it Works for Women With Menopause Symptoms in United States No intervention - Vasomotor Symptoms (VMS) Associated With Menopause | Not yet recruiting | Bayer | 2400 | 2026-11-30 | 2026-09-24 | |
| A Study of Darolutamide Plus Androgen Deprivation Therapy in Patients With Metastatic Hormone-sensitive Prostate Cancer in India Darolutamide plus androgen deprivation therapy - Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) | Not yet recruiting | Bayer | 60 | 2026-11-30 | 2026-10-20 | |
| Efficacy and Safety of a Single Dose of Emodepside Compared to a Single Dose of Albendazole in Adolescents and Adults Infected With Trichuris Incognita Emodepside, Albendazole 400 mg - Trichuris Infection | Phase 2 | Not yet recruiting | Jennifer Keiser | 100 | 2026-11-15 | 2026-08-14 |
| Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections emodepside (BAY 44-4400), Mebendazole 100 MG, similar placebo to mebendazole - Trichuris Trichiura; Infection, Hookworm Infection | Phase 3 | Not yet recruiting | Swiss Tropical & Public Health Institute | 315 | 2026-11-06 | 2026-08-14 |
| Prescriptive Infusion Algorithm (PIA) Prescriptive Infusion Algorithm, AB-1005 - PARKINSON DISEASE (Disorder) | Phase 2 | Not yet recruiting | AskBio Inc | 18 | 2026-11-01 | 2026-07-27 |
| A Study to Learn More About How Well Finerenone Works in Real-world in People With Type 2 Diabetes and Chronic Kidney Disease in Primary Care (IMSS= Instituto Mexicano Del Seguro Social) Finerenone - Type 2 Diabetes, Chronic Kidney Disease (CKD) Stages G2 to G3b | Not yet recruiting | Bayer | 800 | 2026-10-30 | 2026-10-21 | |
| Single-arm, Multi-center Study Evaluating the Acceptance and Feasibility of a Digital Remote Monitoring Tool Configured for Patients With ATTR-CM: ACO-Monitor Luscii - Transthyretin Amyloid Cardiomyopathy (ATTR-CM) | Not yet recruiting | Bayer | 60 | 2026-10-15 | 2026-09-24 | |
| Role of Finerenone in African American Veterans With Diabetic Kidney Disease Finerenone 10 MG, Empagliflozin 10 MG - Diabetic Kidney Disease | Phase 4 | Not yet recruiting | Washington D.C. Veterans Affairs Medical Center | 30 | 2026-10-01 | 2026-08-21 |
| Vericiguat for the Inhibition of Calcific Aortic Valve Stenosis Progression Vericiguat (BAY1021189), Placebo - Calcific Aortic Valve Disease, AORTIC VALVE DISEASES | Phase 2 | Recruiting | West China Hospital | 238 | 2026-09-24 | 2026-09-25 |
| PSMA PET/CT-Guided SBRT Plus Darolutamide in mHSPC Stereotactic Body Radiotherapy (SBRT), Darolutamide 600 mg twice daily, Androgen Deprivation Therapy (ADT) - Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) | Phase 2 | Not yet recruiting | West China Hospital | 254 | 2026-09-15 | 2026-09-10 |
| A Study to Evaluate the Efficacy of VVD-133214 in Combination With Pembrolizumab Compared With Pembrolizumab Alone in Participants With Advanced Cancer of the Colon or Rectum VVD-133214, Pembrolizumab - Colorectal Adenocarcinoma | Phase 2 | Recruiting | Vividion Therapeutics, Inc. | 140 | 2026-09-11 | 2026-10-21 |
| Study of Acoramidis in Patients With Transthyretin Amyloid Cardiomyopathy Acoramidis - Transthyretin Amyloid Cardiomyopathy (ATTR-CM) | Recruiting | Bayer | 500 | 2026-09-07 | 2026-09-15 | |
| Radium-223 for High-Volume Metastatic Hormone Sensitive Prostate Cancer Ra223, Darolutamide Oral Tablet, Androgen Deprivation Therapy (ADT) - Metastatic Hormone-Sensitive Prostate Cance | Phase 2 | Not yet recruiting | Alianza multidisciplinar para la investigación de los tumores genitourinarios -GUARD | 50 | 2026-09-01 | 2026-07-21 |
| A Study to Test How Well BAY 3670549 Works and How Safe it is in Patients With Atrial Fibrillation BAY 3670549, Placebo - Atrial Fibrillation | Phase 2 | Recruiting | Bayer | 360 | 2026-09-01 | 2026-10-20 |
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Neoplasms (104) · Prostatic Neoplasms (95) · Atrial Fibrillation (84) · Hemophilia A (63) · Carcinoma, Hepatocellular (55) · Renal Insufficiency, Chronic (55) · Colorectal Neoplasms (54) · Erectile Dysfunction (53) · Neoplasm Metastasis (50) · Diabetes Mellitus, Type 2 (49) · Multiple Sclerosis (48) · Venous Thromboembolism (48) · Hypertension, Pulmonary (46) · Carcinoma, Renal Cell (44) · Heart Failure (44)
Sorafenib (188) · Rivaroxaban (160) · regorafenib (109) · aflibercept (89) · radium Ra 223 dichloride (64) · darolutamide (59) · Aspirin (56) · Vardenafil Dihydrochloride (55) · Interferon beta-1b (46) · finerenone (44) · Moxifloxacin (41) · copanlisib (41) · Factor VIII (39) · Levonorgestrel (38) · riociguat (37)
United States (935) · Germany (648) · France (348) · Spain (337) · Italy (332) · United Kingdom (325) · Canada (300) · Japan (288) · Belgium (235) · Netherlands (229) · South Korea (228) · Poland (205) · China (192) · Austria (189) · Sweden (186)
Farhad Ravandi-Kashani, MD (4) · Alessandra Ferrajoli, MD (3) · Anne Murray, MD, MSc (3) · Jeong Min Lee, MD (3) · Juergen Dinger, MD, PhD (3) · Marta Alarcon (3) · Robert J Amato, DO (3) · Andre Bergman, MD, PhD (2) · Charles H Hennekens, MD, DrPH (2)
PMID 36005278, PMID 40163217, PMID 27162632, PMID 31535314, PMID 33107592, PMID 34882037, PMID 37523477, PMID 40938666, PMID 21721590, PMID 22371186, PMID 23493136, PMID 25698905, PMID 26931631, PMID 27263466, PMID 28712102, PMID 29466156, PMID 29976287, PMID 30144037, PMID 30807645, PMID 31203241, PMID 31420317, PMID 31654272, PMID 31675266, PMID 31762387, PMID 32105622, PMID 32710396, PMID 33358451, PMID 33414927, PMID 33435412, PMID 33467570, PMID 33892489, PMID 34035833, PMID 34353714, PMID 34866168, PMID 34978027, PMID 36606522, PMID 36619856, PMID 36689698, PMID 37272540, PMID 37745914, PMID 37769113, PMID 37934000, PMID 38044419, PMID 38861286, PMID 38941511, PMID 39935588, PMID 40267388, PMID 40520205, PMID 41196655, PMID 16908937
2014 (52), 2008 (50), 2017 (39), 2009 (38), 2016 (37), 2023 (33), 2019 (31), 2015 (28), 2018 (27), 2005 (25), 2004 (16), 2025 (8), P30CA016672 (2), K23CA139005 (1), P30CA008748 (1)