655 completed, 224 recruiting, 193 unknown, 56 not yet recruiting. 881 Not applicable, 76 Phase 2, 39 Phase 1, 27 Phase 3, 17 Phase 4.
Follow Communication Disorders: new trials by email Literature Review of Communication Disorders trials Research Report on Communication Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lateral Cord Stimulation as a New Treatment for Refractory Spastic Cerebral Palsy Lateral spinal cord surgical implant of electrodes - Cerebral Palsy, Spasticity | Not applicable | Not yet recruiting | Juan Carlos M. Andreani MD | 40 | 2027-06-01 | 2026-04-28 |
| Combined Intervention Program for Non-fluent Aphasia Based on Neuroplasticity CIPAN = MIT + CIAT, MIT + MIT, CIAT + CIAT - Non-fluent Aphasia | Not applicable | Not yet recruiting | Universidad de Granada | 48 | 2027-01-01 | 2026-08-14 |
| Deep Brain Stimulation + Therapy for Stroke Boston Scientific Vercise Deep Brain Stimulation (DBS) System, Rehabilitation Training Protocol - Stroke, Dysarthria | Not applicable | Not yet recruiting | Pirondini, Elvira, PhD | 15 | 2027-01-01 | 2026-09-30 |
| Listen Aphasia Pilot Study LISTEN (AI-based AAC smartphone app) - Aphasia, Malignant Brain Tumor | Not applicable | Not yet recruiting | Dana-Farber Cancer Institute | 80 | 2027-01-01 | 2026-07-28 |
| Effect of a Telerehabilitation-Supported, Family-Centered Early Intervention Program on Neurodevelopmental and Parental Outcomes in Infants at Mild-to-Moderate Risk Remote Family-Centered Early Intervention Program, Standard Information and Routine Follow-up - Development Delay, Motor Skills Disorders | Not applicable | Not yet recruiting | Bengisu Boz Gürboğa | 36 | 2026-11-16 | 2026-10-21 |
| Brain Stimulation Paired With Structured Reading Instruction in Children With Dyslexia Active transcranial electrical stimulation (tES), Sham transcranial electrical stimulation (tES) - Dyslexia, Reading Disability | Not applicable | Recruiting | General Neuro Inc. | 60 | 2026-11-01 | 2026-08-13 |
| BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Aphasia BrainGate Neural Interface System - Expressive Aphasia, Aphasia Following Cerebral Infarction | Not applicable | Not yet recruiting | Leigh R. Hochberg, MD, PhD. | 5 | 2026-11-01 | 2026-10-22 |
| Aprepitant for the Treatment of CLIFAHDD Aprepitant Powder for Oral Suspension - CLIFAHDD, Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay | Early Phase 1 | Recruiting | The University of Texas Health Science Center at San Antonio | 5 | 2026-10-31 | 2026-10-05 |
| Effectiveness of Virtually Simulated Intervention for Patients Having Stuttering Virtually Simulated Intervention, Traditional Speech Therapy - Stuttering | Not applicable | Not yet recruiting | Riphah International University | 44 | 2026-10-25 | 2026-09-28 |
| Evaluation of the Feasibility and Efficacy of a Chronic Brain-computer Interface for Speech Rehabilitation in Patients With Locked-in-syndrome (LIS) Chronic speech BCI - Locked in Syndrome, ALS (Amyotrophic Lateral Sclerosis) | Not applicable | Not yet recruiting | University Hospital, Grenoble | 3 | 2026-10-10 | 2026-07-13 |
| Immediate Effects of Active Prisms on Reading Automaticity and Motor Control in Young Adults With Developmental Dyslexia Individually Selected Active Prisms. - Developmental Dyslexia | Not applicable | Not yet recruiting | Lille University | 66 | 2026-10-01 | 2026-10-09 |
| Using the Babble Boot Camp© Speech Therapy Approach With Babies Born Prematurely Babble Boot Camp - Premature Infants | Not applicable | Not yet recruiting | Murdoch Childrens Research Institute | 86 | 2026-10-01 | 2026-09-02 |
| Safety and Efficacy of NDTx-03 in Children and Adolescents With ASD or SCD NDTx-03, TAU - Autism Spectrum Disorder, Social Communication Disorder | Not applicable | Recruiting | Neudive Inc. | 156 | 2026-09-15 | 2026-09-17 |
| Development and Pilot Testing of Virtually Simulated Intervention for Patients Having Stuttering Virtually Simulated Intervention - Stuttering | Not applicable | Not yet recruiting | Riphah International University | 10 | 2026-09-10 | 2026-09-22 |
| Validation Study of the ExéSem Battery Designed to Differentiate the Contribution of Executive Functions in Semantic Disorders ExéSem cognitive battery - Alzheimer's Disease, Vascular Neurocognitive Disorder | Not yet recruiting | Hospices Civils de Lyon | 140 | 2026-09-09 | 2026-05-07 | |
| Pilot Evaluation of the Developed Syntactic-Semantic Visual Configuration Intervention for Children With Language Impairment Syntactic-Semantic Visual Configuration Intervention (SSVCI) - Language Impairment, Autism | Not applicable | Not yet recruiting | Riphah International University | 20 | 2026-09-01 | 2026-08-26 |
| Study of Cognitive-Linguistic Profiles: The Role of Executive Control in Aphasia Neuropsychological tests, Speech-language assessments - Stroke | Not applicable | Not yet recruiting | University Hospital, Toulouse | 30 | 2026-09-01 | 2026-08-14 |
| Treating Passive Structure Knowledge Deficits in School-Age Children With Developmental Language Disorder Grammar Treatment - Developmental Language Disorders | Not applicable | Not yet recruiting | Ohio University | 150 | 2026-09-01 | 2026-04-01 |
| Cross-cultural Adaptation and Multicenter Validation of the Italian Versions of the Brief Evaluation of Receptive Aphasia (BERA) and SWallowing Assessment in Disorders of Consciousness (SWADOC) Italian SWallowing Assessment in Disorders of Consciousness (SWADOC), Italian Brief Evaluation of Receptive Aphasia (BERA) - Consciousness Disorders, Severe Acquired Brain Injury | Not yet recruiting | Alfonso Magliacano | 79 | 2026-09-01 | 2026-07-17 | |
| taVNS for Letter Learning in Dyslexia active taVNS, sham taVNS - Dyslexia | Not applicable | Suspended | University of Florida | 100 | 2026-09-01 | 2026-05-28 |
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Aphasia (323) · Learning Disabilities (266) · Stroke (209) · Dyslexia (127) · Language Development Disorders (118) · Language Disorders (81) · Speech Disorders (76) · Aphasia, Primary Progressive (75) · Autism Spectrum Disorder (71) · Stuttering (70) · Speech (59) · Dysarthria (57) · Language (56) · Anomia (46)
Pathological Conditions, Signs and Symptoms (1231) · Neurologic Manifestations (1228) · Signs and Symptoms (1228) · Neurobehavioral Manifestations (1226) · Nervous System Diseases (1223) · Language Disorders (801) · Mental Disorders (751) · Neurodevelopmental Disorders (630) · Speech Disorders (518) · Central Nervous System Diseases (424) · Brain Diseases (409) · Cardiovascular Diseases (231) · Vascular Diseases (228) · Cerebrovascular Disorders (226)
Transcranial Direct Current Stimulation (59) · Speech Therapy (40) · Transcranial Magnetic Stimulation (26) · Therapeutics (15) · Language Therapy (10) · Control Groups (9) · Exercise (9) · Standard of Care (7) · Methods (6) · Blood Specimen Collection (5) · Atomoxetine Hydrochloride (4) · Early Intervention, Educational (4) · 2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazole (3) · Deep Brain Stimulation (3) · Fluoxetine (3)
Riphah International University (21) · VA Office of Research and Development (19) · Johns Hopkins University (14) · Chinese University of Hong Kong (13) · IRCCS Eugenio Medea (13) · University of Pennsylvania (13) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (12) · Stanford University (12) · Shirley Ryan AbilityLab (11) · Assistance Publique - Hôpitaux de Paris (10) · Medical College of Wisconsin (10) · Taipei Medical University (10) · Changping Laboratory (9) · The Hong Kong Polytechnic University (9) · University College, London (9)
United States (556) · France (90) · Italy (57) · United Kingdom (56) · Canada (50) · Turkey (Türkiye) (47) · China (33) · Pakistan (33) · Hong Kong (31) · Germany (30) · Belgium (24) · Spain (22) · Taiwan (21) · Brazil (20) · Egypt (19)
Hesheng Liu, PhD (6) · Ru-Lan Hsieh, MD (6) · H. Branch Coslett, MD (4) · Kyrana Tsapkini, PhD (4) · Laurence B. Leonard, PhD (4) · Maya L Henry, PhD (4) · Alexander Kolevzon, MD (3) · Alexander P Leff, Professor (3) · Amy D. Rodriguez, PhD (3) · Hesheng Liu, Ph.D. (3) · John Hart, MD (3) · Jonathan Preston, PhD (3) · Julie L Wambaugh, PhD (3) · Leora Cherney, PhD (3) · Mary Alt, PhD (3)
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R01DC014708 (5), R01DC017476 (5), R01AG055425 (4), R15DC019775 (4), 2019 (3), P50DC014664 (3), R01DC015516 (3), R01DC015642 (3), 2016 (2), P01AG066597 (2), R01DC012824 (2), R01DC019325 (2), R01DC020959 (2), R01DC021429 (2), R01HD059205 (2)