40 completed, 7 unknown, 4 recruiting, 2 terminated. 56 Phase 2, 15 Phase 3, 7 Phase 1.
Follow Anesthesia: new trials by email Literature Review of Anesthesia trials Research Report on Anesthesia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Vasopressin Versus Norepinephrine on Post-operative Mean Pulmonary Arterial Pressure Following Pulmonary Endarterectomy Surgery, Vasopressin, Norepinephrine - Anesthesia, Pulmonary Hypertension | Phase 2 | Not yet recruiting | Fondation Hôpital Saint-Joseph | 90 | 2026-08-01 | 2026-06-02 |
| Intrathecal Bupivacaine With or Without Dexmetomidine for Cesserian Delivery Bupivacaine, Bupivacaine and Dexmedetomidine - Anesthesia | Phase 2 | Completed | Benha University | 300 | 2026-03-15 | 2026-09-04 |
| Prospective IR-led Sedation Feasibility ketamine, Fentanyl (IV), Midazolam - Anesthesia, Sedation and Analgesia | Phase 1 / Phase 2 | Recruiting | CAMC Health System | 40 | 2026-03-02 | 2026-03-09 |
| Aprepitant Treatment to Prevent Postoperative Nausea and Vomiting in Children Undergoing Scoliosis Surgery Aprepitant, Placebo - Spinal Fusion, Nausea and Vomiting, Postoperative | Phase 2 | Recruiting | IWK Health Centre | 100 | 2025-03-17 | 2026-04-27 |
| Intravenous Dexmedetomidine as an Adjuvant to Locoregional Anesthesia in Pediatric Surgery Dexmedetomidine, Placebo administration, Face Legs Activity Cry Consolability scale - Anesthesia, Pediatric Surgery | Phase 2 | Recruiting | University Hospital, Montpellier | 200 | 2025-02-03 | 2026-10-13 |
| Bupivacaine and Epinephrine Injection Study Sensorcaine with Epinephrine, Sham injection - Sinus Disease, Anesthesia | Phase 2 / Phase 3 | Recruiting | Amin Javer | 80 | 2024-11-15 | 2025-05-15 |
| Investigating Near-Threshold Perception During Anesthetic Sedation Functional Magnetic Resonance Imaging (fMRI) with propofol - Propofol, Anesthesia | Phase 2 | Completed | University of Michigan | 40 | 2024-05-10 | 2026-10-30 |
| Dexmedetomidine in Topical Versus Peribulbar Anesthesia for Cataract Surgery Topical dexmedetomidine, Reginal dexmedetomidine - Dexmedetomidine, Cataract Surgery | Phase 2 | Unknown | Kafrelsheikh University | 94 | 2023-07-15 | 2023-09-07 |
| Evaluation of Intubation Conditions Following BX1000 or Rocuronium in Subjects Undergoing Surgery BX1000, Rocuronium Bromide - Neuromuscular Blockade, Anesthesia | Phase 2 | Completed | Baudax Bio | 80 | 2022-10-25 | 2023-08-01 |
| Remimazolam Versus Propofol for Painless Abortion Remimazolam, Propofol, Esketamine - Anesthesia, Abortion Early | Phase 2 | Completed | Maternal and Child Health Hospital of Hubei Province | 100 | 2022-08-01 | 2022-12-02 |
| Neuroimaging Study of Dexmedetomidine-Induced Analgesia Dexmedetomidine - Analgesia, Anesthesia | Phase 2 / Phase 3 | Completed | Massachusetts General Hospital | 17 | 2022-03-04 | 2026-04-23 |
| Comparison Between Oxycodone and Pregabalin as Preemptive Analgesia Oxycodone 20 Mg Oral Tablet, Pregabalin 150mg, Multivitamin with Minerals - Anesthesia | Phase 2 / Phase 3 | Unknown | An-Najah National University | 150 | 2021-08-15 | 2023-07-20 |
| Regional Anesthesia in Pediatric Orthopaedic Patients Ropivacaine - Anesthesia, Local, Anesthesia | Phase 2 / Phase 3 | Completed | Ochsner Health System | 24 | 2021-06-24 | 2025-07-29 |
| Evaluation of Intravenous Lidocaine and Time to Regression of the Sensory Block After Spinal Anesthesia (ELSA Trial) Lidocaine IV, Saline - Anesthesia, Cancer | Phase 2 / Phase 3 | Unknown | Instituto Nacional de Cancer, Brazil | 66 | 2021-06-17 | 2021-07-30 |
| Comparison Between Adjuvants Added to Bupivacaine in Adductor Canal Block Dexamethasone, Dexmedetomidine, Magnesium sulfate - Anesthesia | Phase 2 | Completed | Ain Shams University | 120 | 2021-06-09 | 2022-01-25 |
| Comparison of the Effectiveness of Articaine Local Infusion and Lidocaine Nerve Block in Lower Posterior Tooth Extraction. lidocaine local anesthetic drug, articaine local anesthetic drug - Anesthesia | Phase 2 | Completed | Amjed Fouad Hussein | 60 | 2021-03-15 | 2025-07-09 |
| Effect of mgso4 on Oxygenation and Lung Mechanics in Morbidly Obese Patients During Bariatric Surgery mg sulphate - Anesthesia | Phase 2 | Completed | Ain Shams University | 40 | 2021-03-01 | 2022-07-20 |
| Evaluating Stress Response and Anxiety Score in Paediatric Patients Dexmedetomidine, Placebo - Anxiety and Fear, Anesthesia | Phase 2 | Completed | Universiti Sains Malaysia | 60 | 2020-12-01 | 2021-10-25 |
| EEG Study of IV Methylphenidate-Induced Emergence From Propofol Sedation IV Methylphenidate, Propofol - Anesthesia | Phase 1 / Phase 2 | Withdrawn | Massachusetts General Hospital | 2019-11-01 | 2020-02-21 | |
| the Efficacy and Safety of Sugammadex in Children 0-2 Years Old Sugammadex - Anesthesia, Pediatric Cancer | Phase 2 / Phase 3 | Unknown | Federal Research Institute of Pediatric Hematology, Oncology and Immunology | 62 | 2018-11-15 | 2018-11-02 |
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Agnosia (2) · Coronary Artery Disease (2) · Emergence Delirium (2) · Hypertension, Pulmonary (2) · Neoplasms (2) · Anxiety Disorders (1) · Bites and Stings (1) · Bradycardia (1) · Hemorrhage (1) · Hepatoblastoma (1) · Hypotension (1) · Musculoskeletal Diseases (1) · Pain (1) · Pain, Postoperative (1) · Paranasal Sinus Diseases (1)
Pathological Conditions, Signs and Symptoms (8) · Pathologic Processes (6) · Signs and Symptoms (6) · Cardiovascular Diseases (5) · Neurologic Manifestations (5) · Vascular Diseases (5) · Nervous System Diseases (4) · Neurobehavioral Manifestations (4) · Postoperative Complications (4) · Heart Diseases (3) · Mental Disorders (3) · Respiratory Tract Diseases (3) · Arterial Occlusive Diseases (2) · Arteriosclerosis (2) · Confusion (2)
Dexmedetomidine (10) · Tetracaine (6) · Bupivacaine (5) · Propofol (5) · Ketamine (4) · Sevoflurane (4) · Epinephrine (3) · Fentanyl (3) · Lidocaine (3) · Sodium Chloride (3) · Clonidine (2) · Esketamine (2) · Magnesium Sulfate (2) · Midazolam (2) · Morphine (2)
Massachusetts General Hospital (5) · St. Renatus, LLC (5) · Assiut University (3) · Ain Shams University (2) · Federal University of São Paulo (2) · Universitaire Ziekenhuizen KU Leuven (2) · Amin Javer (1) · Amjed Fouad Hussein (1) · An-Najah National University (1) · Ankara City Hospital Bilkent (1) · Baudax Bio (1) · Baxter Healthcare Corporation (1) · Benha University (1) · CAMC Health System (1) · Cairo University (1)
United States (17) · Egypt (8) · Canada (5) · France (5) · Brazil (4) · Belgium (3) · China (1) · Iran (1) · Iraq (1) · Japan (1) · Malaysia (1) · North Macedonia (1) · Palestinian Territories (1) · Russia (1) · Singapore (1)
Hala S Abdel-Ghaffar, MD (2) · Aleksandra Gavrilovska-Brzanov, MD. Msc (1) · Amy R Deipolyi, M.D., Ph.D. (1) · Anna Konstantinova, MD (1) · Benedito B Joao, MD (1) · Bruno LC Araujo, MSc, EDAIC (1) · Christina Sletten, DDS (1) · Claire Roger, MD (1) · De QH Tran (1) · Elliot V Hersh, DMD, MS, PhD (1) · Elliot V Hersh, DMD, Ph.D. (1) · Farida Ithnin, MBBCh (1) · Hossein Dabbagh, Md, PhD (1) · Huda Zainal Abidin, MD (1)
PMID 23195326, PMID 24238862, PMID 26385664, PMID 28598913, PMID 28943117, PMID 29678977, PMID 33492696, PMID 36143194, PMID 36590787, PMID 37535937, PMID 37713021, PMID 39921932
2025 (1), R01AG053582 (1), R01GM103894 (1)