457 completed, 127 unknown, 85 recruiting, 44 terminated. 340 Not applicable, 94 Phase 4, 79 Phase 2, 66 Phase 3, 30 Phase 1.
Follow Hypotension: new trials by email Literature Review of Hypotension trials Research Report on Hypotension
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| ED90 of Norepinephrine and Phenylephrine Infusion in Patients of Advanced Maternal Age Norepinephrine, Phenylephrine - Adverse Event, Hypotension (MeSH: D007022) | Not applicable | Not yet recruiting | General Hospital of Ningxia Medical University | 60 | 2027-01-31 | 2026-10-26 |
| OB VEGA-Phenylephrine vs Norepinephrine Outcomes Phenylephrine, Norepinephrine - Hypotension During Surgery, Cesarean Birth | Phase 4 | Not yet recruiting | Wake Forest University Health Sciences | 1500 | 2027-01-01 | 2026-10-28 |
| Ceasing Alpha-blockers Early After Resection of the Prostate (The CLEAR Trial) Tamsulosin hydrochloride 0.2 mg, Placebo - Benign Prostatic Hyperplasia | Phase 4 | Not yet recruiting | Shanghai East Hospital | 400 | 2026-12-01 | 2026-09-29 |
| In Elderly Patients, Does Goal-directed Fluid Management Using the Carotid Corrected Flow Time (CC-FT) Index, Compared to Routine Fluid Management, Affect the Occurrence of Post-induction Hypotension? CC-FT Guided Fluid Management Group, Conventional Fluid Management Group - Hypotension (MeSH: D007022), Aged | Not applicable | Not yet recruiting | Zhihong LU | 70 | 2026-11-25 | 2026-11-09 |
| Diastolic Shock Index for Predicting Hemodynamic Instability During Continuous Renal Replacement Therapy Diastolic Shock Index Assessment - Acute Kidney Injury, Hypotension (MeSH: D007022) | Not yet recruiting | Istanbul University - Cerrahpasa | 70 | 2026-11-15 | 2026-11-05 | |
| Continuous BP Monitoring During Sedation for Endoscopy continuous noninvasive blood pressure monitoring - High-Risk Patients Undergoing Gastrointestinal Endoscopy | Not yet recruiting | University of California, Davis | 200 | 2026-11-09 | 2026-11-12 | |
| Dopamine vs. Norepinephrine for Hypotension in Neonates With Pulmonary Hypertension (DONE) Dopamine administration, Norepinephrine - Hypotension and Shock, Pulmonary Hypertension of the Newborn (PPHN) | Phase 4 | Recruiting | University of California, Davis | 30 | 2026-10-30 | 2026-08-18 |
| Granisetron Use, Blood Pressure, and Nausea and Vomiting During Cesarean Delivery Under Spinal Anesthesia Granisetron - Hypotension, Nausea | Not yet recruiting | Kayseri City Hospital | 80 | 2026-10-15 | 2026-10-06 | |
| Pre-induction Norepinephrine in Septic Patients Undergoing Surgery Norepinephrine, Standard Care - Sepsis, Hypotension | Not applicable | Not yet recruiting | Assiut University | 90 | 2026-10-10 | 2026-10-15 |
| Cardiovascular Autonomic Function After Resistance Training Upper-Limb Resistance Training - Spinal Cord Injury | Not applicable | Not yet recruiting | Pusan National University Yangsan Hospital | 20 | 2026-10-01 | 2026-09-03 |
| Carotid Artery Blood Flow, Blood Pressure, and Cardiac Output During Anesthesia in Children Aged 0-5 Years Hypotension (MeSH: D007022) | Not yet recruiting | Karolinska Institutet | 100 | 2026-10-01 | 2026-10-07 | |
| Cardiac Arrest - Ultrasound Detection of Occult Perfusion Cardiac Arrest, Out-Of-Hospital, Hypotension | Recruiting | University of Massachusetts, Worcester | 1400 | 2026-10-01 | 2026-10-27 | |
| ED50/ED90 of Phenylephrine Infusion for Preventing Spinal Anesthesia-Induced Hypotension: Supine vs Left-Tilt 15° Phenylephrine hydrochloride infusion - Hypotension After Spinal Anesthesia | Phase 4 | Not yet recruiting | Peking University People's Hospital | 200 | 2026-09-20 | 2026-09-17 |
| Ultrasound Versus Palpation for Determining Spinal Puncture Level in Cesarean Section Preprocedural ultrasound level identification, Landmark palpation level identification - Cesarean Section (MeSH: D002585), Anesthesia, Spinal (MeSH: D000775) | Not applicable | Not yet recruiting | Kahramanmaras Sutcu Imam University | 66 | 2026-09-01 | 2026-08-27 |
| Autologous Stem Cell Therapy in Patients With Multiple System Atrophy MSCs, Placebo - MSA - Multiple System Atrophy, MSA | Phase 2 | Not yet recruiting | Biocells Medical | 50 | 2026-09-01 | 2026-03-11 |
| Remote Monitoring in Progressive Supranuclear Palsy (PSP) Progressive Supranuclear Palsy, Parkinson Disease | Not yet recruiting | Massachusetts General Hospital | 85 | 2026-09-01 | 2026-07-29 | |
| Blood'up Device Versus Manual Palpation for Arterial Puncture in Healthy Volunteers: A Pilot Randomized Study Under Normal and Simulated Hypotension Arterial blood gas, Simulated hypotension, Arterial Puncture using Blood'Up device - Arterial Puncture, Radial Artery Injury | Not applicable | Not yet recruiting | Centre Hospitalier Régional d'Orléans | 32 | 2026-09-01 | 2026-08-14 |
| Effect of Oxytocin Bolus Versus Slow Infusion on Haemodynamic Stability During Caesarean Section Under Spinal Anaesthesia Oxytocin - Cesarean Section, Hypotension | Not applicable | Not yet recruiting | Khyber Girls Medical College | 60 | 2026-09-01 | 2026-08-25 |
| Impact of Transcutaneous Spinal Stimulation on Blood Pressure and Orthostasis in Spinal Cord Injury Tilt test with stimulation (real-time effects): Intervention 1, 20 sessions of stimulation (Intervention 2) - Spinal Cord Injuries, Hypotension | Not applicable | Not yet recruiting | Kessler Foundation | 10 | 2026-09-01 | 2026-06-29 |
| Internal Jugular Vein Collapsibility Index for Predicting Post-Induction Hypotension IJV-CI Measurement - Hypotension, Anesthesia, General | Not yet recruiting | University of Gaziantep | 42 | 2026-08-15 | 2026-08-03 |
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Hypotension, Orthostatic (149) · Hypertension (53) · Shock (40) · Parkinson Disease (34) · Spinal Cord Injuries (34) · Shy-Drager Syndrome (33) · Multiple System Atrophy (29) · Pure Autonomic Failure (27) · Bradycardia (22) · Post-Exercise Hypotension (22) · Sepsis (21) · Acute Kidney Injury (20) · Syncope (15) · Shock, Septic (14)
Vascular Diseases (821) · Cardiovascular Diseases (810) · Pathological Conditions, Signs and Symptoms (244) · Nervous System Diseases (232) · Autonomic Nervous System Diseases (195) · Primary Dysautonomias (194) · Pathologic Processes (176) · Orthostatic Intolerance (163) · Central Nervous System Diseases (116) · Signs and Symptoms (100) · Brain Diseases (90) · Urogenital Diseases (71) · Basal Ganglia Diseases (67) · Female Urogenital Diseases and Pregnancy Complications (67)
Norepinephrine (52) · Phenylephrine (47) · Ephedrine (26) · Midodrine (25) · Saline Solution (22) · Sodium Chloride (18) · Bupivacaine (17) · Droxidopa (16) · Ondansetron (14) · Propofol (13) · Anesthesia, Spinal (10) · Epinephrine (10) · Ringer's Lactate (10) · Vasoconstrictor Agents (9) · Vasopressins (8)
Seoul National University Hospital (13) · Vanderbilt University Medical Center (13) · Assiut University (11) · University of British Columbia (11) · Mayo Clinic (10) · Vanderbilt University (10) · Cairo University (9) · James J. Peters Veterans Affairs Medical Center (9) · Samuel Lunenfeld Research Institute, Mount Sinai Hospital (7) · Ain Shams University (6) · Ankara City Hospital Bilkent (6) · Assistance Publique - Hôpitaux de Paris (6) · Brigham and Women's Hospital (6) · General Hospital of Ningxia Medical University (6) · Wake Forest University Health Sciences (6)
United States (237) · Turkey (Türkiye) (70) · Canada (62) · France (52) · Egypt (43) · China (35) · South Korea (33) · Italy (30) · United Kingdom (27) · Germany (21) · Brazil (20) · Netherlands (20) · Denmark (18) · Poland (17) · Taiwan (16)
Italo Biaggioni, MD (13) · Jill Wecht, EdD (5) · Adeel Riaz, MD (4) · Jill M Wecht, EdD (3) · Satish R Raj, MD MSCI (3) · Abhik Das, PhD (2) · Adrian E Stephan, MD (2) · Ahmed M Shaat, MD (2) · Alain F Kalmar, MD, PhD (2) · Albert Moore, MD (2) · Christina I. Olofsson, MD, PhD (2) · Emmanouil Stamatakis, PhD (2)
PMID 21762873, PMID 27538531, PMID 28494751, PMID 32619039, PMID 39498822, PMID 11927799, PMID 12119802, PMID 15738343, PMID 17667564, PMID 17959591, PMID 19859776, PMID 20495139, PMID 23835589, PMID 25635593, PMID 28327122, PMID 29090733, PMID 29916861, PMID 30335625, PMID 31989416, PMID 33739123, PMID 40676549, PMID 42475649, PMID 10365009, PMID 10662747, PMID 10851208, PMID 11094595, PMID 11132738, PMID 11227314, PMID 11573596, PMID 11904109, PMID 11916798, PMID 12032019, PMID 12145072, PMID 12832331, PMID 12885750, PMID 12923400, PMID 12960536, PMID 14693603, PMID 14980943, PMID 15066944, PMID 15093843, PMID 15105213, PMID 15220175, PMID 15321207, PMID 15376771, PMID 1539892, PMID 15554749, PMID 15559738, PMID 15666063, PMID 15680647
2023 (5), 2018 (3), 2025 (2), P01HL056693 (2), R01HL144568 (2), U10HD021364 (2), U10HD021373 (2), U10HD021385 (2), U10HD027851 (2), U10HD027853 (2), U10HD027856 (2), U10HD027871 (2), U10HD027880 (2), U10HD027904 (2), U10HD034216 (2)