59 completed, 14 unknown, 7 terminated, 4 recruiting. 85 Phase 3, 15 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 85 | Completed 59, Unknown 14, Terminated 7, Recruiting 4, Active not recruiting 1 |
| Phase 2 | 15 | Completed 10, Unknown 4, Recruiting 1 |
Follow Anesthesia: new trials by email Literature Review of Anesthesia trials Research Report on Anesthesia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Sedation During Endoscopy Using Remimazolam: Efficacy in a Novel Exploration Remimazolam, Propofol - Anesthesia, Sedation | Phase 3 | Completed | Massachusetts General Hospital | 100 | 2026-03-03 | 2026-09-14 |
| Dexmedetomidine in Attenuation of Haemodynamic Response to Laryngoscopy in Controlled Hypertensive Patients Dexmedetomidine, Normal Saline - Hypertension, Hemodynamic Response | Phase 3 | Completed | Sindh Institute of Urology and Transplantation | 70 | 2025-01-01 | 2026-04-29 |
| Bupivacaine and Epinephrine Injection Study Sensorcaine with Epinephrine, Sham injection - Sinus Disease, Anesthesia | Phase 2 / Phase 3 | Recruiting | Amin Javer | 80 | 2024-11-15 | 2025-05-15 |
| A Multicenter, Open, Controlled, Phase III Clinical Study to Evaluate the Efficacy and Safety of Cipepofol Injection for General Anesthesia in Pediatric Patients Undergoing Elective Surgery Cipepofol, Propofol - Anesthesia | Phase 3 | Completed | Haisco Pharmaceutical Group Co., Ltd. | 190 | 2024-04-07 | 2025-07-22 |
| External Oblique Intercostal Block Versus Paravertebral Block for Postoperative Analgesia in Laparoscopic Cholecystectomy Patients The external oblique intercostal block, Paravertebral block - Anesthesia | Phase 3 | Unknown | Assiut University | 80 | 2024-02-01 | 2024-01-12 |
| The Effect of Mannitol Volume With Changes in Osmolarity in Traumatic Brain Injury Mannitol - Anesthesia, Traumatic Brain Injury | Phase 3 | Completed | Universitas Diponegoro | 64 | 2023-11-01 | 2026-06-11 |
| Effect of Sedative and Anxiolytic Premedication on Children Experience After General Anesthesia Midazolam, Dexmedetomidine, Placebo - Anesthesia | Phase 3 | Recruiting | University Hospital, Montpellier | 1000 | 2023-04-18 | 2026-07-17 |
| Intravenous Methadone in Perioperative Acute and Chronic Management in Chinese Adult Cardiac Surgical Patients Methadone, Morphine - Pain, Postoperative, Pain, Acute | Phase 3 | Completed | Chinese University of Hong Kong | 86 | 2023-01-15 | 2026-10-23 |
| Impact of Pre-spinal Atropine on Post Spinal Hemodynamics and Cardiac Output Measured by Electrical Cardiometry in Caesarean Delivery atropine, Isotonic saline - Anesthesia | Phase 3 | Completed | Ain Shams University | 60 | 2022-12-25 | 2023-07-20 |
| THRIVE Feasibility Trial Anesthetic technique Propofol TIVA, Anesthetic technique inhaled agent - Surgery--Complications, Anesthesia Complication | Phase 3 | Completed | Washington University School of Medicine | 300 | 2022-09-29 | 2023-11-24 |
| Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial) Admixture of propofol and etomidate at a ratio by volume of 75%/25% (P7E2), Admixture of propofol and etomidate at a ratio by volume of 25%/75% (P2E7) - Anesthesia, Propofol Adverse Reaction | Phase 3 | Recruiting | University of Texas Southwestern Medical Center | 200 | 2022-09-19 | 2026-01-20 |
| Norepinephrine for Prevention of Intraoperative Hypotension in Infants Undergoing Kasai Portoenterostomy Norepinephrine Bitartrate, Placebo - Anesthesia, Pediatrics | Phase 3 | Completed | Kasr El Aini Hospital | 31 | 2022-08-28 | 2024-07-09 |
| Does IV Magnesium Improve Quality of Recovery With ERAS Protocols in Laparoscopic Colorectal Surgery? IV Medications, placebo - Colo-rectal Cancer, Anesthesia | Phase 3 | Completed | Thomas Jefferson University | 90 | 2022-05-27 | 2024-04-09 |
| Dexmedetomidine Infusion on Intraoperative Propofol,Fentanyl Requirements in Spine Surgery for Pediatric Cancer Patients Precedex Injectable Product, Saline - Spine Cancer, Anesthesia | Phase 3 | Unknown | Children's Cancer Hospital Egypt 57357 | 38 | 2022-05-17 | 2022-08-09 |
| Neuroimaging Study of Dexmedetomidine-Induced Analgesia Dexmedetomidine - Analgesia, Anesthesia | Phase 2 / Phase 3 | Completed | Massachusetts General Hospital | 17 | 2022-03-04 | 2026-04-23 |
| Caudal Block Versus Dorsal Penile Nerve Block Plus Ring Block for Pain Management of Different Surgical Techniques of Circumcision in Infants and Children Caudal block, Dorsal penile nerve block plus ring block, Circumcision with Plastibell - Anesthesia, Anesthesia, Local | Phase 3 | Unknown | King Saud University | 120 | 2022-03-01 | 2022-02-10 |
| IV Dexmedetomidine in the Duration of Spinal Anesthesia With Hyperbaric Bupivacaine: Double Blind Randomized Trial. Dexmedetomidine injection, Sodium Chloride 0.9% infusion - Anesthesia, Dexmedetomidine | Phase 3 | Unknown | Hospital Central "Dr. Ignacio Morones Prieto" | 60 | 2022-01-31 | 2022-06-13 |
| Comparison Between Oxycodone and Pregabalin as Preemptive Analgesia Oxycodone 20 Mg Oral Tablet, Pregabalin 150mg, Multivitamin with Minerals - Anesthesia | Phase 2 / Phase 3 | Unknown | An-Najah National University | 150 | 2021-08-15 | 2023-07-20 |
| Opioid-Free Anesthesia in Cardiac Surgery Dexmédétomidine 0.5 g/kg + lidocaine 1.5 mg/kg, Remifentanil - Anesthesia | Phase 3 | Completed | University Hospital, Rouen | 268 | 2021-07-22 | 2026-03-31 |
| Comparison of an Opioid-Free Anesthesia Protocol Versus Standard Practices on Early and Late Post-operative Recovery Opioid Free Anaesthesia protocol, standard practice protocol based on the use of opioids (sufentanil or remifentanil) - Anesthesia, Anesthesia; Adverse Effect | Phase 3 | Unknown | University Hospital, Angers | 140 | 2021-07-12 | 2021-10-14 |
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Pain, Postoperative (5) · Agnosia (4) · Postoperative Complications (4) · Acute Pain (3) · Emergence Delirium (3) · Chronic Pain (2) · Neoplasms (2) · Pathologic Processes (2) · Postoperative Nausea and Vomiting (2) · Anxiety Disorders (1) · Biliary Atresia (1) · Brain Injuries (1) · Brain Injuries, Traumatic (1) · Colonic Neoplasms (1) · Communicable Diseases (1)
Pathological Conditions, Signs and Symptoms (19) · Nervous System Diseases (13) · Signs and Symptoms (13) · Pathologic Processes (12) · Neurologic Manifestations (11) · Neurobehavioral Manifestations (7) · Postoperative Complications (7) · Pain (6) · Mental Disorders (5) · Respiratory Tract Diseases (5) · Cardiovascular Diseases (4) · Perceptual Disorders (4) · Central Nervous System Diseases (3) · Chemically-Induced Disorders (3) · Confusion (3)
Dexmedetomidine (17) · Propofol (9) · Sevoflurane (9) · Sodium Chloride (8) · Lidocaine (7) · Ketamine (6) · Remifentanil (6) · Rocuronium (6) · Sugammadex (6) · Fentanyl (5) · Midazolam (5) · Bupivacaine (4) · Saline Solution (4) · Tetracaine (4) · Desflurane (3)
Merck Sharp & Dohme LLC (9) · Hopital Foch (4) · Massachusetts General Hospital (4) · St. Renatus, LLC (4) · Assiut University (2) · B. Braun Melsungen AG (2) · Cairo University (2) · Hospira, now a wholly owned subsidiary of Pfizer (2) · Kangbuk Samsung Hospital (2) · University of Saskatchewan (2) · Ain Shams University (1) · Amin Javer (1) · An-Najah National University (1) · Azienda Ospedaliera San Gerardo di Monza (1) · Bagcilar Training and Research Hospital (1)
United States (23) · France (11) · Canada (8) · Egypt (6) · Brazil (3) · China (3) · Germany (2) · Italy (2) · Japan (2) · Mexico (2) · South Korea (2) · Australia (1) · Denmark (1) · Greece (1) · Hong Kong (1)
Marc Fischler, MD (4) · Kyoungho Ryu, M.D. (2) · Paul A. Moore, DMD/PhD/MPH (2) · Ahmed Hasanin, Professor (1) · Andrew J Davidson, MD (1) · Anna Konstantinova, MD (1) · Antonio Pesenti, MD (1) · Aria P Hayanto, Sp.An-TI (1) · Ben Lim, MD (1) · Boleslav Kosharskyy, MD (1) · Bruno LC Araujo, MSc, EDAIC (1) · Christine Oryhan, MD (1) · Conor Mc Donnell, MD (1) · David W Hewson, MBBS (1)
PMID 18641105, PMID 19194156, PMID 19348675, PMID 19455040, PMID 22012178, PMID 24238862, PMID 24491036, PMID 25179459, PMID 25829395, PMID 26126940, PMID 26892312, PMID 27481679, PMID 29340574, PMID 29452808, PMID 29678977, PMID 29739917, PMID 29793595, PMID 29961015, PMID 30336856, PMID 30777900, PMID 30926686, PMID 33492696, PMID 34838109, PMID 35857365, PMID 36590787, PMID 37068889, PMID 37535937, PMID 38520467, PMID 38830745, PMID 39283983, PMID 39921932, PMID 40250622, PMID 40255646, PMID 40455731, PMID 41950401, PMID 42090240
2004 (1), 2008 (1), R01AG053582 (1)