196 completed, 86 unknown, 37 recruiting, 29 not yet recruiting. 122 Not applicable, 96 Phase 4, 80 Phase 3, 68 Phase 2, 30 Phase 1.
Follow this drug Literature Review of Magnesium Sulfate trials Research Report on Magnesium Sulfate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Magnesium Sulfate in Pediatric Burn Dressing Changes magnesium sulfate, Normal Saline (0.9% NaCl) - Pediatric Burns | Phase 1 | Not yet recruiting | Hennepin Healthcare Research Institute | 10 | 2027-12-01 | 2026-10-09 |
| Intravenous Paracetamol Versus Magnesium Sulfate for Control of Shivering Following Spinal Anesthesia in Cesarean Section Paracetamol, Magnesium Sulfate - Shivering, Post-Spinal Shivering | Phase 4 | Not yet recruiting | Assiut University | 90 | 2026-11-01 | 2026-10-02 |
| Effect of Labetalol, Magnesium Sulfate, or Lidocaine on Opioid Consumption During Laparoscopic Cholecystectomy Labetalol, Magnesium Sulfate, Lidocaine - Postoperative Pain, Cholelithiasis | Phase 4 | Not yet recruiting | Assiut University | 90 | 2026-11-01 | 2026-10-08 |
| Multiple Adjunct Therapies to Improve Immunotherapy Treatment in Patients With Locally Advanced or Metastatic Melanoma or Advanced Hepatocellular Cancer Biospecimen Collection, Cholecalciferol, Computed Tomography - Advanced Hepatocellular Carcinoma, Advanced Melanoma | Phase 2 | Not yet recruiting | University of Southern California | 46 | 2026-11-01 | 2026-09-23 |
| Efficacy of High-Dose Continuous Intravenous Magnesium Sulfate Infusion vs Standard Intravenous Magnesium Sulfate Therapy in Status Asthmaticus in the ED ้High-dose Magnesium sulphate, standard-dose Magnesium Sulfate - Asthma Exacerbation, Emergency Department | Not applicable | Not yet recruiting | Thammasat University | 72 | 2026-11-01 | 2026-08-31 |
| Magnesium Sulphate for Neonatal Asphyxia and Length of Hospital Stay Magnesium sulphate, Supportive care and standard neonatal intensive care unit care - Duration of Hospitalization, Neonatal Mortality Rate | Not applicable | Not yet recruiting | Sargodha Medical College | 72 | 2026-11-01 | 2026-09-23 |
| Anti-inflammatory Effect of MgSO₄ in Patients With Moderate Traumatic Brain Injury by Measurming Nucleotide-binding Oligomerization Domain-Like Receptor Pyrin Domain-containing 3 (NLRP3) Inflammasome-a Multiprotein Complex Magnesium sulfate (MgSO4), Normal Saline - Traumatic Brain Injuries | Phase 4 | Not yet recruiting | Assiut University | 64 | 2026-10-01 | 2026-08-13 |
| MAGNEsium With meToprolol for Rate Control In Atrial Fibrillation Magnesium Sulfate 2g, Magnesium Sulfate 4g, Saline (0.9% NaCl) - Atrial Flutter With Rapid Ventricular Response | Phase 3 | Not yet recruiting | Wake Forest University Health Sciences | 196 | 2026-10-01 | 2026-06-29 |
| Epidural Analgesia Versus Opioid-sparing Analgesia for Open Ventral Hernia Repair With Transversus Abdominis Release Bupivicaine, Fentanyl, Thoracic epidural analgesia - Ventral Hernia, Ventral Hernia Repair | Phase 4 | Recruiting | Northwestern University | 40 | 2026-09-25 | 2026-10-07 |
| Magnesium Sulfate With Standard Combined Costoclavicular-Suprascapular Block for Pain Relief After Shoulder Arthroscopy. Bupivacaine, Magnesium sulfate (MgSO4), Normal Saline (NS) - Shoulder Arthroscopy, Postoperative Pain | Not applicable | Not yet recruiting | Assiut University | 84 | 2026-09-01 | 2026-09-01 |
| Magnesium Sulphate Versus Dexamethasone With TAP Block for Post-Cesarean Analgesia Magnesium Sulphate 500 mg, Dexamethasone - Cesarean Section Complications | Not applicable | Not yet recruiting | Khyber Teaching Hospital | 80 | 2026-09-01 | 2026-08-19 |
| Biomarkers in Management of Post Partum Preeclampsia Magnesium Sulfate - Preeclampsia Severe, Preeclampsia Postpartum | Phase 4 | Not yet recruiting | Alexander Harrison | 100 | 2026-09-01 | 2026-09-09 |
| Topical Magnesium Sulfate Versus Peritonsillar Bupivacaine for Post-Tonsillectomy Pain Relief in Children Magnesium Sulfate, Bupivacaine - Post-tonsillectomy Pain, Tonsillectomy | Phase 4 | Not yet recruiting | Assiut University | 40 | 2026-09-01 | 2026-08-12 |
| Trial Evaluating the Analgesic Efficacy of Magnesium Sulfate as an Adjuvant to Bupivacaine in Local Wound Infiltration for Patients Undergoing Modified Radical Mastectomy (MRM) With Axillary Clearance Magnesium Sulfate 750 mg with Bupivacaine 0.5% for Local Wound Infiltration, Bupivacaine 0.5% + Normal Saline - Modified Radical Mastectomy | Not applicable | Not yet recruiting | King Hussein Cancer Center | 70 | 2026-09-01 | 2026-08-31 |
| Effect of Targeting Upper Normal Serum Magnesium Levels on Norepinephrine Requirements in Septic Shock Patients magnesium sulfate, standard care treatment - Septic Shock, Sepsis | Not applicable | Recruiting | Alexandria University | 60 | 2026-07-30 | 2026-10-06 |
| Oral Versus Intravenous Magnesium on Emergence Delirium Magnesium glycinate, Magnesium sulfate injection, Oral juice and intravenous saline - Magnesium, Emergence Delirium | Phase 2 / Phase 3 | Recruiting | Tanta University | 360 | 2026-07-01 | 2026-07-06 |
| COMPARISON OF OUTCOME OF HYPOXIC ISCHEMIC ENCEPHLOPATHY MANAGED WITH COMBINATION OF MAGNESIUM SULPHATE AND MELATONIN VERSUS MAGNESIUM SULPHATE ALONE MgSO4 (seizure prevention), Melatonin , Mgso4 - HIE - Hypoxic - Ischemic Encephalopathy | Phase 3 | Not yet recruiting | University of Child Health Sciences and Children's Hospital, Lahore | 80 | 2026-07-01 | 2026-06-17 |
| Intra-Arterial Magnesium Therapy After Mechanical Thrombectomy in Acute Ischemic Stroke Magnesium sulfate - Acute Ischemic Stroke | Phase 1 | Recruiting | Baylor College of Medicine | 30 | 2026-07-01 | 2026-10-01 |
| High- vs Standard-Dose Intravenous Magnesium for Acute Headache Magnesium Sulfate 2 grams, Magnesium Sulfate 4 G, Paracetamol 1 g - Acute Headache, Migraine | Not applicable | Recruiting | University of Monastir | 300 | 2026-06-01 | 2026-08-21 |
| Hemodynamic Effect of Dexmedetomidine Versus Magnesium Sulphate as an Adjuvant to Lidocaine in Preemptive Peribulbar Block in Patients Undergoing Dacryocystorhinostomy Under General Anesthesia Lidocaine + Dexmedetomidine, Lidocaine + Magnesium sulphate, Lidocaine - Hemodynamic Effect, Dexmedetomidine | Not applicable | Recruiting | Cairo University | 60 | 2026-05-16 | 2026-06-30 |
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Pain, Postoperative (50) · Agnosia (19) · Pain (19) · Pre-Eclampsia (18) · Asthma (10) · Atrial Fibrillation (9) · Emergence Delirium (8) · Acute Pain (6) · Brain Injuries, Traumatic (5) · Breast Neoplasms (5) · Cerebral Palsy (5) · Premature Birth (5) · Stroke (5) · Neuralgia (4) · Obstetric Labor, Premature (4)
Assiut University (49) · Cairo University (19) · Ain Shams University (17) · Seoul National University Bundang Hospital (14) · Zagazig University (7) · University of Monastir (6) · Alexandria University (5) · Tanta University (5) · Mansoura University (4) · Seoul National University Hospital (4) · Beni-Suef University (3) · Fayoum University (3) · Fayoum University Hospital (3) · Kasr El Aini Hospital (3) · National Cancer Institute, Egypt (3)
Egypt (117) · United States (58) · South Korea (22) · Turkey (Türkiye) (18) · Canada (13) · Brazil (12) · Pakistan (11) · Tunisia (7) · Switzerland (5) · China (4) · France (4) · Greece (4) · Indonesia (4) · Iran (4) · India (3)
Ali Asgher, Mbbs, FCPS (2) · Alshaimaa Kamel, M.D (2) · Christoph A Czarnetzki, MD, MBA (2) · David E. Leaf, MD, MMSc (2) · Fabricio T Mendonca, MD, TSA (2) · Hala Abdel-Ghaffar, MD (2) · Hesham Ah Abdel Mohaiemn, MD (2) · Ismar L Cavalcanti, PhD (2) · Marwa Ib Abdo, MD (2) · Semir Nouira, Professor (2) · Shruti Gupta, MD, MPH (2) · Suzanne Schuh, MD (2) · A Pranskunas, MD (1) · Abeer S Goda, MD (1)
PMID 37815037, PMID 35947046, PMID 23121612, PMID 17042843, PMID 17513629, PMID 19919585, PMID 22183158, PMID 23635996, PMID 23669270, PMID 30985540, PMID 10389803, PMID 10580682, PMID 10601925, PMID 10671850, PMID 11506113, PMID 11530753, PMID 12057549, PMID 12183720, PMID 12190806, PMID 12198045, PMID 12229137, PMID 12803269, PMID 12873949, PMID 13243706, PMID 14766688, PMID 14980919, PMID 15235946, PMID 156513, PMID 16278131, PMID 16311277, PMID 16324031, PMID 16334446, PMID 16418039, PMID 16632328, PMID 16731324, PMID 16835255, PMID 17166799, PMID 17202008, PMID 17241503, PMID 17261216, PMID 17299013, PMID 1734773, PMID 17601897, PMID 18042893, PMID 18044291, PMID 18343266, PMID 18428988, PMID 18640467, PMID 18753646, PMID 19250287
2019 (2), 2009 (1), K23DK125672 (1), P30CA014089 (1), P30CA015083 (1), R01HD021453 (1), R34HL152047 (1), R34HL166859 (1), U01NS044364 (1), U10HD021410 (1), U10HD021414 (1), U10HD027860 (1), U10HD027861 (1), U10HD027869 (1), U10HD027905 (1)