2499 completed, 937 unknown, 456 recruiting, 265 terminated. 1713 Not applicable, 644 Phase 4, 318 Phase 3, 297 Phase 2, 118 Phase 1.
Follow Coronary Artery Disease: new trials by email Literature Review of Coronary Artery Disease trials Research Report on Coronary Artery Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Fibroblast Growth Factor-1 (FGF-1) for the Treatment of Coronary Heart Disease Human Recombinant Fibroblast Growth Factor-1 (FGF 1-141) - low dose, Human Recombinant Fibroblast Growth Factor-1 (FGF1-141) - high dose, Placebo - Coronary Disease, Coronary Heart Disease | Phase 2 | Not yet recruiting | Venturis Therapeutics, Inc. | 150 | 2027-09-01 | 2026-08-19 |
| Heart tEam Decision-making Assisted by Revaz AI Trial Revaz AI - Coronary Artery Disease | Not applicable | Not yet recruiting | University of Calgary | 712 | 2027-04-01 | 2026-09-24 |
| OPTIA-AF Trial: Rhythm-Guided Antithrombotic Strategy After AF Ablation Oral anticoagulation, Single antiplatelet therapy - Atrial Fibrillation (AF), Coronary Artery Disease | Phase 4 | Not yet recruiting | Ewha Womans University Mokdong Hospital | 2 | 2027-03-01 | 2026-03-27 |
| A Trial Assessing the Effectiveness of Evolocumab in Reducing the Plaque Burden in Participants With Subclinical Atheroma Evolocumab, Routine Lipid Management, Autoinjector - Coronary Artery Disease, Hypercholesterolemia | Phase 4 | Not yet recruiting | Amgen | 308 | 2027-01-31 | 2026-09-21 |
| Utilizing Carbon Dioxide for Assessing Coronary Blood Flow in Subjects With Coronary Artery Disease RespirAct - Coronary Artery Disease | Not applicable | Not yet recruiting | Indiana University | 30 | 2027-01-10 | 2026-05-26 |
| Nursing Intervention for Adaptation After Myocardial Revascularization Nursing Intervention Program, Usual Care - Coronary Artery Disease, Myocardial Revascularization | Not applicable | Not yet recruiting | Universidad de la Sabana | 40 | 2027-01-01 | 2026-05-08 |
| Photobiomodulation in Coronary Artery Bypass Grafting With No-Touch vs Conventional Saphenous Vein Harvesting. Photobiomodulation Therapy, Sham Laser irradiation, Conventional Saphenous Vein Harvesting - Coronary Artery Disease, Coronary Artery Bypass Graft (CABG) | Not applicable | Not yet recruiting | Federal University of São Paulo | 292 | 2027-01-01 | 2026-10-07 |
| Intraoperative Ultrasound Assessment of Coronary Artery and Bypass Graft Blood Flow During CABG Intraoperative Ultrasound Blood Flow Measurement - Coronary Artery Disease | Not yet recruiting | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 190 | 2027-01-01 | 2026-08-11 | |
| wCAR-Austria: A Women-Specific Score to Assess Cardiovascular Risk in Women Aged 40 to 65 Arm 1: wCAR-CARE - Precision Prevention (Arm A), Guideline-directed standard of care - Cardiovascular Diseases (CVD), Coronary Artery Disease | Not applicable | Not yet recruiting | Women's Heart Austria | 800 | 2027-01-01 | 2026-09-30 |
| Modified Jailed Balloon Technique vs Jailed Wire Technique in Coronary Bifurcation Intervention jailed wire technique, Modified jailed balloon technique - Coronary Artery Disease | Not applicable | Not yet recruiting | Assiut University | 140 | 2027-01-01 | 2026-10-14 |
| Rapid Inflation/Deflation Compared With Prolonged High-Pressure Balloon Inflation Prolonged inflation, Rapid inflation - Coronary Artery Disease, Coronary Stent Occlusion | Not applicable | Not yet recruiting | Central Arkansas Veterans Healthcare System | 40 | 2027-01-01 | 2026-10-21 |
| PCI With GDMT Versus GDMT Alone for Patients With Ischemic Cardiomyopathy and Reduced LVEF Percutaneous coronary intervention, Guideline-directed medical therapy - Heart Failure With Reduced Ejection Fraction, Coronary Artery Disease | Not applicable | Not yet recruiting | Nanjing First Hospital, Nanjing Medical University | 1154 | 2026-12-30 | 2026-05-28 |
| PREventive Invasive Strategy for Obstructive Coronary Artery Disease With Vulnerable Plaque Evaluated by CoroNary Computed Tomography Angiography-2 Initial Invasive Strategy, Initial Conservative Strategy - Coronary Artery Disease | Not applicable | Not yet recruiting | Duk-Woo Park, MD | 2500 | 2026-12-30 | 2026-10-21 |
| Clinical Evidence With Biomarker Confirmation for PPMI in PCI Clinical Trials Study Biomarker testing - Peri-procedural Myocardial Infarction, Heart Failure Hospitalization | Not yet recruiting | Baim Institute for Clinical Research | 1000 | 2026-12-01 | 2026-09-30 | |
| PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study Clinical Decision Aid, Standard Care - Heart Failure, Coronary Artery Disease | Not yet recruiting | Medical College of Wisconsin | 60 | 2026-12-01 | 2025-10-14 | |
| International Study of Comparative Health Effectiveness With Medical and Invasive Approaches-Left Ventricular Dysfunction Trial Guideline-directed medical therapy (GDMT), Coronary artery bypass grafting (CABG), Percutaneous coronary intervention (PCI). - Coronary Artery Disease, Cognitive Impairment | Phase 3 | Suspended | NYU Langone Health | 1200 | 2026-12-01 | 2026-06-05 |
| Efficacy and Safety of the Angionix Balloon in Patients With Coronary Artery Disease Undergoing PTCA Angionix Balloon - Coronary Artery Disease | Not yet recruiting | Yonsei University | 600 | 2026-11-09 | 2026-10-09 | |
| Comparison of Fractional FLOW Reserve Outcomes With Drug-Coated Balloon-Based Versus Drug-Eluting Stent-Only Percutaneous Coronary Intervention Strategies Drug-coated balloon-based intervention, Drug-eluting stent-based intervention - Coronary Artery Disease, Percutaneous Coronary Intervention | Not applicable | Not yet recruiting | Korea University Guro Hospital | 100 | 2026-11-09 | 2026-10-01 |
| REFINE-CAC Protocol: Risk Evaluation With AI-CPA + HCS For Patients IN Whom Calcium is confirmEd to Improve Coronary Artery Disease Care Heartflow Analysis - CAD - Coronary Artery Disease | Not applicable | Not yet recruiting | HeartFlow, Inc. | 500 | 2026-11-01 | 2026-10-02 |
| Artificial Intelligence - Based Opportunistic Coronary Artery Calcium Scoring on Routine Chest-CT Scan Coronary Artery Calcification, Cardiovascular Risk | Not yet recruiting | University of Cologne | 1950 | 2026-11-01 | 2026-09-09 |
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Abbott Medical Devices (79) · Yonsei University (61) · Seung-Jung Park (58) · China National Center for Cardiovascular Diseases (54) · National Heart, Lung, and Blood Institute (NHLBI) (48) · Boston Scientific Corporation (46) · Seoul National University Hospital (44) · Cordis US Corp. (41) · University of Florida (39) · Ottawa Heart Institute Research Corporation (38) · Medtronic Vascular (34) · Fundación EPIC (33) · Insel Gruppe AG, University Hospital Bern (33) · Samsung Medical Center (30) · University of Roma La Sapienza (29)
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PMID 35224730, PMID 40875095, PMID 25940520, PMID 24746650, PMID 19463432, PMID 20142198, PMID 23468513, PMID 23523454, PMID 17296825, PMID 23232250, PMID 24510638, PMID 26825231, PMID 29089314, PMID 30165437, PMID 31561250, PMID 32227755, PMID 32890442, PMID 33939604, PMID 34056911, PMID 35641327, PMID 37256598, PMID 37619976, PMID 37745109, PMID 40590244, PMID 41913985, PMID 17145250, PMID 17982182, PMID 18765162, PMID 19228612, PMID 19717846, PMID 20129555, PMID 21232717, PMID 21670242, PMID 22017936, PMID 22032711, PMID 22070834, PMID 22115661, PMID 25173339, PMID 25176289, PMID 25593120, PMID 25825008, PMID 26585622, PMID 28317458, PMID 28495897, PMID 29217001, PMID 29891620, PMID 30475845, PMID 30586701, PMID 32295417, PMID 32588238
2017 (7), 2023 (7), 2025 (6), 2018 (5), 2016 (4), U01HL088942 (4), 2014 (3), 2015 (3), 2019 (3), 2009 (2), K23HL105897 (2), P50HL110789 (2), R01AG031750 (2), R01HL092954 (2), R01HL142297 (2)