340 completed, 108 unknown, 25 recruiting, 24 terminated. 220 Not applicable, 172 Phase 4, 40 Phase 3, 38 Phase 2, 18 Phase 1.
Follow this drug Literature Review of Sevoflurane trials Research Report on Sevoflurane
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Ketamine-Propofol Total Intravenous Anesthesia Versus Sevoflurane-Based Anesthesia on Postoperative Vomiting in Children Undergoing Strabismus Surgery Ketamine and Propofol, Sevoflurane - Postoperative Vomiting, Postoperative Nausea and Vomiting | Phase 4 | Not yet recruiting | Assiut University | 50 | 2026-11-01 | 2026-10-13 |
| Sevoflurane Versus Propofol Anesthesia in Intracardiac Echocardiography-Guided Atrial Fibrillation Ablation Sevoflurane, propofol - Persistent Atrial Fibrillation | Phase 4 | Not yet recruiting | Hüseyin Ulaş Pinar | 124 | 2026-10-01 | 2026-10-16 |
| Ciprofol, Propofol and Sevoflurane for Postoperative Delirium in Elderly Brain Tumor Patients Ciprofol, Propofol, Sevoflurane - Brain Neoplasms, Delirium - Postoperative | Not applicable | Not yet recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 381 | 2026-09-30 | 2026-09-02 |
| Pre-emptive Local Anesthesia and Sevoflurane Consumption in Pediatric Dental Anesthesia Pre-emptive Local Anesthesia, Articaine With Epinephrine, Sevoflurane - Sevoflurane Consumption | Not applicable | Not yet recruiting | TC Erciyes University | 80 | 2026-08-01 | 2026-05-27 |
| Erector Spinae Plane Block and Low-Flow Anaesthesia in Laparoscopic Cholecystectomy Erector Spinae Plane Block, Low Fresh Gas Flow (0.5 L/min), Standard Fresh Gas Flow (3 L/min) - Postoperative Pain, Laparoscopic Cholecystectomy | Not applicable | Recruiting | Taksim Egitim ve Arastirma Hastanesi | 72 | 2026-06-18 | 2026-06-23 |
| Remimazolam-Flumazenil Versus Sevoflurane for Hysteroscopic Day Surgery Remimazolam, Flumazenil, Sevoflurane - Hysteroscopy, Ambulatory Surgery | Phase 4 | Not yet recruiting | Chung-Ang University Gwangmyeong Hospital | 124 | 2026-06-01 | 2026-06-23 |
| Response Surface Modeling of Remimazolam and Sevoflurane Remimazolam (Byfavo), Sevoflurane (Volatile Anesthetic) - Laparoscopic Surgery | Not applicable | Recruiting | Pusan National University Yangsan Hospital | 80 | 2026-05-15 | 2026-06-02 |
| Effects Of Propofol And Sevoflurane On Plasma Mirna Levels İn Living Kidney Donors Sevoflurane, propofol - Kidney Transplant | Not applicable | Recruiting | University of Gaziantep | 34 | 2026-05-01 | 2026-08-12 |
| Comparison of the Effects of Sevoflurane and Desflurane on Optic Nerve Sheath Diameter During Laparoscopic Surgery Sevoflurane, Desflurane - Intracranial Pressure, Laparoscopic Surgery | Not applicable | Completed | Medipol University | 63 | 2026-04-15 | 2026-08-04 |
| Comparison of Sevoflurane and Desflurane on ANI in Patients Undergoing General Anesthesia: a Prospective Randomized Controlled Study Desflurane, Sevoflurane - General Anesthesia | Not applicable | Not yet recruiting | Pusan National University Yangsan Hospital | 80 | 2026-04-01 | 2026-04-06 |
| Low-Flow Sevoflurane and Desflurane Anesthesia in Laparoscopic Cholecystectomy Sevoflurane, Desflurane - Laparoscopic Cholecystectomy, Postoperative Sore Throat | Not applicable | Completed | Kayseri City Hospital | 80 | 2026-03-20 | 2026-08-25 |
| Effect of Sevoflurane vs Desflurane on Mechanical Power in Laparoscopic Cholecystectomy Sevoflurane, Desflurane - Perioperative Respiratory Mechanics | Not applicable | Completed | Konya City Hospital | 138 | 2026-03-09 | 2026-09-15 |
| Propofol Versus Sevoflurane Anesthesia on the Intraocular Pressure and Hemodynamics in Patient Undergoing Cyclophotocoagulation Propofol and Fentanyl administration, Sevoflurane and fentanyl administration - Patient Cataract | Not applicable | Not yet recruiting | Sohag University | 40 | 2026-03-01 | 2026-03-27 |
| Effect of Total Intravenous Anesthesia vs Inhalational Anesthesia on the Level of Inflammatory Markers Venous blood sampling preoperatively, Venous blood sampling at 6 hours postoperative, Venous blood sampling at 24 hours postoperative - Anesthesia | Not applicable | Active not recruiting | Ain Shams University | 40 | 2026-02-01 | 2026-09-16 |
| Comparison of the Metabolomic Effects of Sevoflurane and Desflurane Anesthesia in Laparoscopic Cholecystectomy Sevoflurane, Desflurane - Sevoflurane Desflurane, Metabolomic Effect | Not applicable | Not yet recruiting | Harran University | 80 | 2026-02-01 | 2026-02-23 |
| Low-Flow Anesthesia and Perioperative Atelectasis in Laparoscopic Bariatric Surgery Sevoflurane with normal-flow anesthesia, Sevoflurane with low-flow anesthesia - Atelectasis, Pulmonary Complications | Not applicable | Completed | Istanbul University | 60 | 2026-01-15 | 2026-05-20 |
| Sevoflurane Sedation in Patients With Septic Shock Sevoflurane, Control Group - Shock, Septic | Phase 2 | Not yet recruiting | University of Zurich | 153 | 2026-01-01 | 2025-04-01 |
| The Effects of Three Different Anesthetic Methods on Postoperative Agitation SEVOFLURANE, TIVA, CIVIA - Emergence Agitation, Septoplasty Surgeries | Not applicable | Completed | Inonu University | 3 | 2025-12-25 | 2026-05-07 |
| Equivalent MAC in General Anesthesia Sevoflurane + Remifentanil, Sevoflurane + Propofol + Remifentanil - General Anesthesia, Intraoperative Monitoring | Completed | Sakarya University | 60 | 2025-11-01 | 2026-03-10 | |
| MR-Evaluation of Renal Function in Anesthetized Pediatric Patients Anesthesia Maintenance Agent - Renal Blood Flow, Anesthesia | Phase 4 | Not yet recruiting | Uppsala University | 50 | 2025-10-01 | 2025-03-25 |
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Emergence Delirium (38) · Pain, Postoperative (29) · Delirium (17) · Respiratory Aspiration (17) · Postoperative Cognitive Complications (12) · Neoplasms (11) · Pain (11) · Postoperative Nausea and Vomiting (9) · Breast Neoplasms (8) · Cognitive Dysfunction (8) · Colonic Neoplasms (7) · Coronary Artery Disease (7) · Postoperative Complications (7) · Respiratory Distress Syndrome (7) · Lung Neoplasms (6)
Seoul National University Hospital (13) · University of Zurich (10) · Tanta University (9) · Inonu University (8) · Kangbuk Samsung Hospital (7) · Konkuk University Medical Center (7) · University Hospital, Clermont-Ferrand (7) · Yonsei University (7) · Assiut University (6) · Cukurova University (6) · Kaohsiung Medical University Chung-Ho Memorial Hospital (6) · Ajou University School of Medicine (5) · Huazhong University of Science and Technology (5) · Istanbul University (5) · Pusan National University Yangsan Hospital (5)
China (63) · South Korea (59) · United States (53) · Turkey (Türkiye) (45) · Egypt (33) · France (23) · Canada (19) · Germany (19) · Switzerland (18) · Italy (14) · Belgium (12) · Taiwan (11) · Greece (10) · Brazil (9) · Russia (9)
Alibek Kh Mustafin, Professor (4) · Dong-Xin Wang, MD, PhD (4) · Kyoungho Ryu, M.D. (4) · Feray Erdil, MD (3) · James Zacny, Ph.D. (3) · Sameh M El-Sherbiny, MD (3) · Stanley SC Wong, MBBS (3) · XiaoFeng Shen, MD (3) · Zhi-Fu Wu (3) · Adrian E Stephan, MD (2) · Beatrice Beck Schimmer, Prof MD (2) · Bryce Weber, MD FRCSC (2) · Eberhard F Kochs, MD (2)
PMID 12127688, PMID 12760985, PMID 14570648, PMID 15114210, PMID 15905753, PMID 15949912, PMID 18540930, PMID 20930611, PMID 21935924, PMID 22192060, PMID 23411725, PMID 26296299, PMID 27413741, PMID 29187413, PMID 38954871, PMID 10366002, PMID 10400452, PMID 10517999, PMID 10536559, PMID 10758459, PMID 10793585, PMID 10960408, PMID 11052579, PMID 11193758, PMID 11256129, PMID 11307125, PMID 12005471, PMID 12225610, PMID 12773983, PMID 14644354, PMID 15277925, PMID 15306730, PMID 15308095, PMID 15321492, PMID 15488052, PMID 15502041, PMID 15901026, PMID 15915027, PMID 16026399, PMID 16056258, PMID 16078916, PMID 16146475, PMID 16369168, PMID 16927929, PMID 17002789, PMID 17158128, PMID 17179249, PMID 17307778, PMID 17479030, PMID 17585216
R01DA008391 (3), 2014 (2), 2008 (1), 2019 (1), 2025 (1), P30CA168524 (1), R35GM146822 (1)