46 terminated. 46 Phase 1, 13 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 46 | Terminated 46 |
| Phase 2 | 13 | Terminated 13 |
Follow Pain: new trials by email Literature Review of Pain trials Research Report on Pain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Managing Chronic Tendon Pain by Metformin Metformin, Placebo - Tendinopathy, Chronic Pain | Phase 1 | Terminated | James Wang | 21 | 2024-05-24 | 2026-08-27 |
| A Study to Test the Effects of Kindolor at Different Doses in Healthy Adults Kindolor Tosylate, Placebo - Chronic Pain | Phase 1 | Terminated | Lohocla Research Corporation | 16 | 2024-04-21 | 2026-05-27 |
| Study Evaluating the Safety and Feasibility of Platelet-rich Plasma to Treat Facetogenic Low Back Pain Angel® Concentrated Platelet Rich Plasma System, Platelet Rich Plasma - Lumbar Spondylosis | Phase 1 | Terminated | Matthew Pingree | 4 | 2023-01-05 | 2024-07-17 |
| Oxytocin for Hypermobile Ehlers-Danlos Syndrome Oxytocin, Placebo - Hypermobile Ehlers-Danlos Syndrome, Pain Assessment | Phase 1 / Phase 2 | Terminated | Baylor College of Medicine | 2 | 2022-05-13 | 2025-08-28 |
| The Using Postoperative Ketamine and Exploring the Effect on Endometriosis Pain (UPKEEEP) Study Ketamine, Placebo - Endometriosis, Post Operative Pain | Phase 1 | Terminated | NYU Langone Health | 1 | 2022-04-12 | 2025-03-28 |
| Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for Heart Disease AlloRx - Congestive Heart Failure, Angina | Phase 1 | Terminated | The Foundation for Orthopaedics and Regenerative Medicine | 3 | 2022-02-01 | 2026-10-20 |
| Safety and Efficacy of XT-150 for Treatment of Neuropathic Pain XT-150, Placebo - Neuropathic Pain | Phase 1 | Terminated | Xalud Therapeutics, Inc. | 5 | 2021-04-14 | 2023-01-23 |
| Non-Opioid Pain Medications After Intracapsular Adenotonsillectomy Oxycodone, Ibuprofen, Acetaminophen - Adenotonsillectomy, Post-operative Analgesia | Phase 1 / Phase 2 | Terminated | David Chi, MD | 73 | 2021-04-13 | 2024-08-30 |
| Single Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ST-2427 ST-2427, Placebo - Acute, Post-operative Pain | Phase 1 | Terminated | SiteOne Therapeutics, Inc. | 24 | 2021-03-04 | 2023-08-03 |
| Safety and Efficacy of SX600 Administered by Lumbosacral Transforaminal Epidural Injection for Radicular Pain SX600, Placebo - Lumbar Radiculopathy | Phase 1 / Phase 2 | Terminated | SpineThera Australia PTY LTD | 56 | 2019-11-04 | 2024-01-10 |
| Effects of Intravenous GSK3858279 on a Battery of Evoked Pain Tests in Healthy Volunteers Placebo, GSK3858279 - Pain | Phase 1 | Terminated | GlaxoSmithKline | 21 | 2019-10-15 | 2024-03-18 |
| Improving Labour Induction Analgesia: Epidural Fentanyl Bolus at Epidural Initiation for Induction of Labour Epidural Fentanyl Bolus, Standard Epidural Group - Epidural, Labor Pain | Phase 1 | Terminated | University of Saskatchewan | 5 | 2019-07-01 | 2020-11-04 |
| Pgp Transporter and CNS Biodistribution of Ondansetron in Healthy Volunteers Ondansetron 8mg with Saline & Tariquidar, Ondansetron 16mg with Saline & Tariquidar - Neuropathic Pain | Phase 1 | Terminated | Washington University School of Medicine | 14 | 2019-05-20 | 2022-04-07 |
| Acute Pain Management in Patients on Opioid Replacement Therapy HYDROmorphone Injectable Solution, Ketamine, Placebos - Opioid-use Disorder, Pain, Acute | Phase 1 | Terminated | University of California, San Francisco | 1 | 2018-10-31 | 2022-10-10 |
| Non-opioids for Analgesia After Adenotonsillectomy in Children Oxycodone, Ibuprofen, Acetaminophen - Adenotonsillectomy, Post-operative Analgesia | Phase 1 / Phase 2 | Terminated | David Chi, MD | 268 | 2018-10-25 | 2021-11-10 |
| Mechanical Diagnosis and Treatment and/or Steroid Injections for Lumbar Radiculopathy Exercise (MDT approach), Transforaminal epidural steroid injection (20mg dexamethasone 0.5cc lidocaine 2%) - Sciatica, Lumbosacral Radiculopathy | Phase 1 | Terminated | University of Alberta | 27 | 2017-10-01 | 2022-04-11 |
| Ketamine and Magnesium in Post-operative Pain Control in Patients Treated With Opioids Ketamine plus Magnesium sulfate, Placebo - Chronic Pain | Phase 1 | Terminated | Milton S. Hershey Medical Center | 20 | 2017-07-01 | 2022-05-27 |
| Efficacy of Buprenorphine on Postoperative Endodontic Analgesia Buprenorphine, Sterile saline, lidocaine, epinephrine (Local anesthetic) - Postoperative Pain | Phase 1 | Terminated | University Hospitals Cleveland Medical Center | 10 | 2017-04-01 | 2019-04-23 |
| Effects of Local Anaesthetic Infusion Rates on Nerve Block Duration Varying infusion rates of Ropivacaine 0.2% - Other Acute Postoperative Pain, Pain, Postoperative | Phase 1 | Terminated | Nordsjaellands Hospital | 60 | 2016-10-10 | 2017-03-30 |
| Effects of IV-Administered Ca-DTPA and Zn-DTPA To Treat Patients With Gadolinium Deposition Disease Calcium DTPA, Zinc DTPA - Headache, Cognitive Disturbance | Phase 1 / Phase 2 | Terminated | University of North Carolina, Chapel Hill | 1 | 2016-10-01 | 2018-04-06 |
Showing 20 of 46. Sign in to see all of them.
Pain, Postoperative (8) · Agnosia (4) · Angina Pectoris (3) · Cancer Pain (3) · Chronic Pain (3) · Headache (3) · Neoplasms (3) · Neuralgia (3) · Acute Pain (2) · Low Back Pain (2) · Motor Activity (2) · Osteoarthritis (2) · Sciatica (2) · Vomiting (2)
Neurologic Manifestations (46) · Pathological Conditions, Signs and Symptoms (46) · Signs and Symptoms (46) · Nervous System Diseases (13) · Pathologic Processes (11) · Postoperative Complications (8) · Musculoskeletal Diseases (5) · Neuromuscular Diseases (5) · Peripheral Nervous System Diseases (5) · Cardiovascular Diseases (4) · Joint Diseases (4) · Neurobehavioral Manifestations (4) · Perceptual Disorders (4) · Mental Disorders (3)
Lidocaine (4) · Ketamine (3) · Sodium Chloride (3) · Acetaminophen (2) · Ibuprofen (2) · Ketorolac (2) · Ketorolac Tromethamine (2) · Oxycodone (2) · Ropivacaine (2) · Acupuncture Therapy (1) · Anesthetics, Local (1) · Azacitidine (1) · Bupivacaine (1) · Buprenorphine (1) · Clonidine (1)
David Chi, MD (2) · AstraZeneca (1) · Baylor College of Medicine (1) · Biogen (1) · Boehringer Ingelheim (1) · Boston Scientific Corporation (1) · Center for Medicinal Cannabis Research (1) · Columbia University (1) · Costantine Albany (1) · Danish Headache Center (1) · Drexel University College of Medicine (1) · Eli Lilly and Company (1) · Foundation for Biomedical Research and Innovation (1) · Geisinger Clinic (1) · GlaxoSmithKline (1)
United States (29) · Canada (4) · Germany (3) · Australia (2) · Denmark (2) · Antigua and Barbuda (1) · Argentina (1) · Japan (1) · Netherlands (1) · United Kingdom (1)
David H Chi, MD (2) · Amit Mahipal, M.D. (1) · Brendan Lee, MD, PhD (1) · Bruno Gagnon, MD, MSC (1) · Bryan Chambers (1) · Chadwick Prodromos, MD (1) · Costantine Albany, M.D. (1) · D. Andrew Tompkins, MD MHS (1) · Daniel S Tsze, MD, MPH (1) · David D Childs, MD (1) · David L Steed, MD (1) · Donald I Abrams, M.D. (1)
PMID 22372531, PMID 23369112, PMID 27295489, PMID 29570501, PMID 36452492, PMID 39250326, PMID 40396501, PMID 41090674
1UG3DA049599 (1), 2009 (1), 2019 (1), UH3DA047680 (1)