68 terminated. 68 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 68 | Terminated 68 |
Follow Pain, Postoperative: new trials by email Literature Review of Pain, Postoperative trials Research Report on Pain, Postoperative
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| ZYNRELEF for Pain Management in Total Knee Arthroplasty Bupivacaine-Meloxicam 400 Mg-12 Mg/14 mL Injectable Solution, Extended Release - Post Operative Pain, Osteoarthritis, Knee | Phase 4 | Terminated | Baptist Health South Florida | 29 | 2023-03-09 | 2026-05-28 |
| Comparing Local Anesthesia With and Without iPACK Block Real iPACK block (20 mL of 0.25% bupivacaine, 2.5mcg/mL epinephrine, and 50mcg/mL preservative-free dexamethasone), Sham iPACK block with 20ml normal saline - Osteo Arthritis Knee, Analgesia | Phase 4 | Terminated | University of Calgary | 10 | 2022-10-30 | 2026-06-01 |
| Sternotomies and PectoIntercostal Fascia Blocks in Fast-Track Cardiac Anesthesiology Pectointercostal fascia blocks, Placebo - Post-operative Pain | Phase 4 | Terminated | University of Alberta | 1 | 2022-09-22 | 2023-12-18 |
| Liposomal Bupivacaine vs Continuous Nerve Catheters for Below the Knee Amputations Liposomal bupivacaine, Bupivacaine Hydrochloride 0.5 % Injectable Solution - Pain, Postoperative, Amputation | Phase 4 | Terminated | Aurora Quaye | 11 | 2022-08-15 | 2026-01-27 |
| Safety and Pharmacokinetics of N1539 in Children 2 to <17 Years of Age Following Surgery N1539 - Post Operative Pain | Phase 4 | Terminated | Baudax Bio | 19 | 2022-02-24 | 2023-09-13 |
| Pain Relief After Trapeziectomy: Ibuprofen & Acetaminophen Versus Oxycodone NSAID capsules, Opioid capsule - Pain, Postoperative, Osteoarthritis Thumb | Phase 4 | Terminated | Stanford University | 73 | 2021-12-27 | 2026-10-27 |
| Sciatic Block in Contralateral Limb Phantom and Residual Limb Pain 10 mL 2% lidocaine, 10 mL preservative free saline - Pain, Amputation | Phase 4 | Terminated | Northwestern University | 1 | 2021-09-01 | 2025-03-03 |
| Opioid Free vs. Standard Perioperative Pain Regimen for Anterior Cervical Discectomy and Fusion (ACDF) Surgery Opioid Analgesic, Opioid-Free Postoperative Pain Regimen - Opioid Use, Spinal Diseases | Phase 4 | Terminated | Vanderbilt University Medical Center | 8 | 2021-08-01 | 2024-01-31 |
| iPACK Block With Dexamethasone For Total Knee Replacement ropivacaine 0.25% with epinephrine and 6mg dexamethasone, Saline - Knee Osteoarthritis, Acute Pain | Phase 4 | Terminated | University of California, San Diego | 14 | 2021-06-07 | 2023-11-07 |
| Continuous Nerve Block Block vs Combination of Single Block Plus Intravenous Lidocaine for Postoperative Pain. Continuous Erector Spinae Plane Nerve Block, Continuous Quadratus Lumborum Nerve Block, Single Erector Spinae Plane Nerve Block - Postoperative Pain | Phase 4 | Terminated | Jeremy Kearns | 17 | 2021-05-26 | 2023-09-13 |
| Opioid & Steroid Use Following Tonsillectomy in Pediatric Patients Dexamethasone, Analgesics - Pain, Postoperative | Phase 4 | Terminated | Duke University | 24 | 2021-04-14 | 2024-12-27 |
| Postoperative Pain Control Following Renal Transplant Intravenous Lidocaine, Transversus abdominis plane (TAP) block, Quadratus Lumborum (QL) Block - Kidney Transplant; Complications, Pain, Postoperative | Phase 4 | Terminated | George Washington University | 31 | 2021-03-16 | 2024-03-18 |
| Methadone for Spinal Fusion Surgery. Methadone, Morphine - Pain, Postoperative, Back Pain | Phase 4 | Terminated | University of Aarhus | 114 | 2021-02-26 | 2024-11-25 |
| Optimizing Recovery in Abdominoplasty Liposomal bupivacaine, Standard of care - Postoperative Pain | Phase 4 | Terminated | University of Wisconsin, Madison | 2 | 2021-01-05 | 2024-08-07 |
| Dexamethasone and Postoperative Bleeding Following Tonsillectomy in Children Dexamethasone, Sodium chloride - Pain, Postoperative, Tonsillar Bleeding | Phase 4 | Terminated | Walid HABRE | 523 | 2020-11-01 | 2024-04-18 |
| A Randomized Control Trial Comparing Analgesic Benefits of Ultrasound-guided Single vs Continuous Quadratus Lumborum Blocks (QLB)vs Intrathecal Morphine(ITM) for Post Cesarean Section Pain Intrathecal morphine sulfate (ITM), Bupivacaine hydrochloride, ropivacaine hydrochloride - Pain, Postoperative | Phase 4 | Terminated | The University of Texas Health Science Center, Houston | 3 | 2020-05-22 | 2022-05-16 |
| Intraoperative Methadone for Postoperative Pain Control After Thoracic Surgery Methadone - Postoperative Pain | Phase 4 | Terminated | Endeavor Health | 40 | 2019-10-09 | 2021-12-21 |
| Comparison of TAP, Anterior QL, or ESP Block for Elective Cesarean Section Ropivacaine, TAP block, QL block - Pain, Postoperative, Cesarean Section | Phase 4 | Terminated | Duke University | 12 | 2019-09-12 | 2022-01-12 |
| Oral Pregabalin as Preemptive Analgesia in Abdominal Hysterectomy Pregabalin 300mg, Placebo - Pain, Postoperative, Analgesia | Phase 4 | Terminated | Universidade Federal de Alfenas | 58 | 2019-09-02 | 2021-03-04 |
| Impact of Quadratus Lumborum Block on Recovery Profile After Ventral Hernia Repair Quadratus Lumborum Block, Standard Medical Management - Pain, Postoperative, Opioid Use | Phase 4 | Terminated | University of Wisconsin, Madison | 14 | 2019-05-06 | 2022-09-21 |
Showing 20 of 68. Sign in to see all of them.
Pain (11) · Agnosia (7) · Postoperative Nausea and Vomiting (4) · Osteoarthritis (3) · Osteoarthritis, Knee (2) · Patient Satisfaction (2) · Phantom Limb (2) · Acute Pain (1) · Back Pain (1) · Body Weight Changes (1) · Bursitis (1) · Drug-Related Side Effects and Adverse Reactions (1) · Finger Injuries (1) · Hand Injuries (1)
Neurologic Manifestations (68) · Pathologic Processes (68) · Pathological Conditions, Signs and Symptoms (68) · Postoperative Complications (68) · Signs and Symptoms (68) · Pain (57) · Nervous System Diseases (9) · Neurobehavioral Manifestations (9) · Perceptual Disorders (9) · Musculoskeletal Diseases (8) · Joint Diseases (6) · Arthritis (5) · Rheumatic Diseases (5) · Signs and Symptoms, Digestive (5) · Nausea (4)
Dexamethasone (12) · Acetaminophen (9) · Ropivacaine (9) · Bupivacaine (8) · Sodium Chloride (8) · Morphine (6) · Gabapentin (4) · Methadone (4) · Epinephrine (3) · Fentanyl (3) · Ketamine (3) · Oxycodone (3) · Saline Solution (3) · Analgesia, Patient-Controlled (2) · Analgesics, Opioid (2)
University of Aarhus (3) · University of California, San Diego (3) · Cedars-Sinai Medical Center (2) · Duke University (2) · Glostrup University Hospital, Copenhagen (2) · Northwestern University (2) · Pfizer (2) · University of Wisconsin, Madison (2) · Vanderbilt University Medical Center (2) · Albany Medical College (1) · Aurora Quaye (1) · Baptist Health South Florida (1) · Baudax Bio (1) · Beth Israel Deaconess Medical Center (1) · Centre Hospitalier Universitaire de Nice (1)
United States (41) · Denmark (6) · Canada (5) · Germany (3) · Switzerland (3) · Argentina (1) · Belgium (1) · Brazil (1) · Estonia (1) · Finland (1) · France (1) · Israel (1) · Italy (1) · United Kingdom (1)
Ole Mathiesen, MD (2) · Albert Losken, MD (1) · Amanda Kumar, MD (1) · Amy Ladd, MD (1) · Andrew J Kobets, MD, MHS (1) · Anthony Ho, MD (1) · Anthony Machi, MD (1) · Antoun M Nader, MD (1) · Aurora Quaye, MD (1) · Birgitte V Christensen, M.D. (1) · Brian Ilfeld, M.D., M.S. (1) · Brian M Ilfeld, M.D., M.S. (1) · Carla S Ceron, PhD (1) · Carlos M de Barros, BSc (1)
PMID 16691088, PMID 19066382, PMID 23423135, PMID 25767411, PMID 28348503
2008 (2), 2005 (1), 2016 (1), 2017 (1), 2019 (1)