558 completed, 146 recruiting, 84 active not recruiting, 77 terminated. 468 Not applicable, 114 Phase 2, 81 Phase 4, 60 Phase 1, 39 Phase 3.
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Precision-Medicine Diagnostic Support in Hospitalized Veterans With Acute Kidney Injury PRECISE-AKI Clinical Decision Support Tool - Acute Kidney Injury (AKI) | Not applicable | Not yet recruiting | VA Office of Research and Development | 60 | 2028-01-01 | 2025-10-16 |
| Optimizing Dysphagia Treatment Delivery in Acute Care: A Hybrid Efficacy Implementation Trial Expiratory muscle strength training (EMST), Standard of Care Dysphagia Treatment, Intensive Dysphagia Treatment - Dysphagia, Critical Illness | Not applicable | Not yet recruiting | Vanderbilt University Medical Center | 120 | 2027-07-01 | 2026-10-14 |
| Swallowing Impairments in ICU Survivors and Community-Dwelling Adults Dysphagia, Healthy Aging | Withdrawn | Vanderbilt University Medical Center | 2027-04-01 | 2026-06-02 | ||
| Multi-Modal Digital Monitoring of Disease Symptoms Huntington's Disease Huntington Disease | Not yet recruiting | BioSensics | 75 | 2027-01-31 | 2026-10-13 | |
| Pilot Study Evaluating Tumor Microenvironment Interaction in Solid Tumor Patients 68Ga-FAPI-46 - Solid Tumor Cancer, Solid Tumor Malignancy | Early Phase 1 | Withdrawn | Eben Rosenthal | 2027-01-01 | 2026-01-21 | |
| The Application of Lifestyle Enhancing Validated Integrative Therapies for Everyday Pain in Cirrhosis High-touch self-management program, Low-touch self-management program - Cirrhoses, Liver | Not applicable | Not yet recruiting | University of Pennsylvania | 625 | 2027-01-01 | 2026-10-02 |
| Intraoperative Optical Coherence Tomography for Ophthalmic Surgical Guidance - Cornea Optical coherence tomography (OCT) - Corneal Transplantation | Not yet recruiting | Vanderbilt University Medical Center | 24 | 2027-01-01 | 2026-03-16 | |
| Measurement-Based Care to Support Buprenorphine-Naloxone Treatment in Outpatient Addiction Clinics Bup-MBC - Opioid Use Disorder | Not applicable | Not yet recruiting | Vanderbilt University Medical Center | 140 | 2026-12-01 | 2026-09-30 |
| Visualization of the Colon Through Use of the Magnetic Flexible Endoscope (MFE) in Participants With Inflammatory Bowel Disease (IBD) Magnetic Flexible Endoscope (MFE) - Inflammatory Bowel Disease (IBD), Colonoscopy | Not applicable | Not yet recruiting | Vanderbilt University Medical Center | 6 | 2026-12-01 | 2026-08-20 |
| HMB Plus Vitamin D to Preserve Muscle in Older Adults Starting Semaglutide Calcium-HMB Plus Vitamin D3, Matching placebo - Type 2 Diabetes Mellitus (T2DM), Sarcopenia | Phase 2 | Not yet recruiting | Vanderbilt University Medical Center | 90 | 2026-12-01 | 2026-08-28 |
| Cognitive Enhancement in Recurrent Depression (The COG-D-R Study) Depression Cognitive Training, Non-Specific Cognitive Training, tDCS (active stimulation) - Aging, Depression | Not applicable | Not yet recruiting | Vanderbilt University Medical Center | 69 | 2026-12-01 | 2026-10-21 |
| Tracing Of Real-time glu13Cose Metabolism in Human Immune Cells - Intensive Care Unit 13C6-Glucose - Glucose, Metabolism | Not applicable | Not yet recruiting | Vanderbilt University Medical Center | 25 | 2026-11-01 | 2026-09-09 |
| Cholinergic Deep Brain Stimulation for Alzheimer's Disease Device Implantation- Boston Scientific, VERCISE GENUS™ system, DBS Stimulation - Boston Scientific, VERCISE GENUS™ system - Alzheimer Disease, Early Onset, Dementia | Not applicable | Enrolling by invitation | Vanderbilt University Medical Center | 2 | 2026-11-01 | 2026-09-01 |
| Artificial Intelligence to Scale Early Rheumatic Heart Disease Detection AI assisted echocardiography - Rheumatic Heart Disease | Not applicable | Not yet recruiting | Children's Hospital Medical Center, Cincinnati | 62 | 2026-11-01 | 2026-10-16 |
| Use of Pyrvinium to Reverse Stomach Precancerous Conditions Placebo, Pyrvinium, Blood biomarkers analyses - STOMACH NEOPLASM | Phase 2 | Not yet recruiting | National University Hospital, Singapore | 50 | 2026-11-01 | 2026-10-13 |
| The Impact of Perioperative Lidocaine Infusions on Enhanced Recovery After Non-Cardiac Surgery Lidocaine HCl 0.8% in D5W, Dextrose 5% in water - Pain, Post Operative Analgesia | Phase 4 | Not yet recruiting | Vanderbilt University Medical Center | 2290 | 2026-10-31 | 2026-10-15 |
| Advanced Robotic Techniques and Rapid Onsite Evaluation for Minimally Invasive Diagnosis and Next-Generation Sequencing. Rapid onsite evaluation - Peripheral Pulmonary Lesions (PPLs) | Not applicable | Not yet recruiting | Vanderbilt University Medical Center | 400 | 2026-10-01 | 2026-07-06 |
| Sleep Harmonization Via Bundled Team-Based Interventions in the ICU Nighttime noise & light reduction, Clustering patient-care interactions, Non-pharmacologic sleep aids - Sleep Deprivation, Critical Illness | Not applicable | Not yet recruiting | University of California, San Diego | 62500 | 2026-10-01 | 2026-09-25 |
| Metabolic Flux Analysis in Metabolic Dysfunction-Associated Steatotic Liver Disease Bariatric surgery, Stable isotope tracer infusion, MRI/MRE - Metabolic Dysfunction-Associated Steatotic Liver Disease, Metabolic Dysfunction-Associated Steatohepatitis | Not applicable | Not yet recruiting | Vanderbilt University Medical Center | 20 | 2026-10-01 | 2026-08-12 |
| Transition to Ambulatory Bariatric Surgery (TABS) Trial Same Day Discharge - Obesity and Obesity-related Medical Conditions, Bariatric Surgery | Not applicable | Recruiting | Vanderbilt University Medical Center | 200 | 2026-10-01 | 2026-09-21 |
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Obesity (44) · Cognitive Dysfunction (30) · Critical Illness (29) · Hypertension (29) · Depression (23) · Diabetes Mellitus (23) · COVID-19 (21) · Delirium (21) · Diabetes Mellitus, Type 2 (21) · Postural Orthostatic Tachycardia Syndrome (19) · Parkinson Disease (18) · Autism Spectrum Disorder (17) · Anemia, Sickle Cell (16) · Diabetes Mellitus, Type 1 (16) · Pain (16)
Sodium Chloride (23) · Saline Solution (13) · Standard of Care (10) · Blood Specimen Collection (9) · Educational Status (9) · Lidocaine (9) · Tobacco Use Cessation Devices (9) · Dexamethasone (8) · Hydroxyurea (8) · 2-(aminomethyl)phenol (7) · Influenza Vaccines (7) · Dexmedetomidine (6) · semaglutide (6) · Bupivacaine (5) · Midodrine (5)
United States (927) · Canada (18) · Nigeria (13) · France (9) · United Kingdom (6) · Australia (5) · South Africa (5) · Mozambique (4) · Germany (3) · Ghana (3) · Brazil (2) · Finland (2) · Iceland (2) · Italy (2) · Poland (2)
Italo Biaggioni, MD (12) · Adrian Hernandez, MD (8) · Susanna Naggie, MD (8) · Matthew W Semler, MD, MSc (7) · Satish R Raj, MD MSCI (7) · William Martinez, MD, MS (7) · Cyndya Shibao, MD (5) · Donald H Arnold, MD, MPH (5) · Jonathan D Casey, MD, MSc (5) · Michael R DeBaun, MD, MPH (5) · Naji Abumrad, MD (5) · Todd W Rice, MD, MSc (5) · Cyndya Shibao, M.D (4) · David T. Kent, MD (4) · Fabien Maldonado, MD (4)
PMID 40946805, PMID 26541392, PMID 26599819, PMID 27922747, PMID 28639856, PMID 30952488, PMID 33929361, PMID 37326325, PMID 38334063, PMID 40243391, PMID 40885487, PMID 10037110, PMID 10738419, PMID 10946944, PMID 11018167, PMID 11068116, PMID 11230313, PMID 11438138, PMID 11473065, PMID 11690728, PMID 12147930, PMID 12589633, PMID 12861145, PMID 15133328, PMID 15232785, PMID 15622223, PMID 15710782, PMID 15840177, PMID 15979939, PMID 15986343, PMID 16320034, PMID 16943900, PMID 17141563, PMID 17321157, PMID 17709712, PMID 17905655, PMID 18052736, PMID 18377862, PMID 1846122, PMID 1860713, PMID 1879381, PMID 19434384, PMID 19464947, PMID 19884021, PMID 20004430, PMID 20083523, PMID 20110457, PMID 20357371, PMID 20414197, PMID 20457158
P30CA068485 (12), U24TR001608 (9), U01HG010225 (4), R01CA149633 (3), R01DC015997 (3), R01HL144568 (3), R21EB035783 (3), K23AT011569 (2), K23DK106511 (2), K23HL103976 (2), R01AI125642 (2), R01CA202936 (2), R01DK058697 (2), R01DK110166 (2), R01DK131129 (2)