396 completed, 109 unknown, 45 recruiting, 33 not yet recruiting. 274 Not applicable, 142 Phase 4, 65 Phase 3, 58 Phase 2, 15 Phase 1.
Follow Postoperative Nausea and Vomiting: new trials by email Literature Review of Postoperative Nausea and Vomiting trials Research Report on Postoperative Nausea and Vomiting
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Binaural Beats and Postoperative Nausea and Vomiting in Laparoscopic Cholecystectomy Binaural Beats Application, Placebo - Laparoscopic Cholecystectomy | Not applicable | Not yet recruiting | Bitlis Eren University | 76 | 2027-01-01 | 2026-10-21 |
| The Use of a Comfort Tote to Improve Recovery in Pediatric and Adolescent Patients After Surgery The Therapeutic Comfort Tote, The Modified Comfort Tote - Adolescent Idiopathic Scoliosis, Postoperative Pain, Acute | Not applicable | Recruiting | Columbia University | 50 | 2026-12-01 | 2026-10-09 |
| Amisulpride Injection for the Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Surgery Amisulpride, Ondansetron - PONV | Not applicable | Not yet recruiting | Qianfoshan Hospital | 718 | 2026-11-15 | 2026-10-23 |
| Effect of Ketamine-Propofol Total Intravenous Anesthesia Versus Sevoflurane-Based Anesthesia on Postoperative Vomiting in Children Undergoing Strabismus Surgery Ketamine and Propofol, Sevoflurane - Postoperative Vomiting, Postoperative Nausea and Vomiting | Phase 4 | Not yet recruiting | Assiut University | 50 | 2026-11-01 | 2026-10-13 |
| The Effect of White and Pink Noise in Patients Undergoing Total Hip and Knee Arthroplasty White Noise Intervention, Pink Noise Intervention - Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting | Not applicable | Not yet recruiting | Ataturk University | 165 | 2026-10-10 | 2026-10-05 |
| Remote Assessment of Pain and Recovery Quality After Surgery Using a Digital Form: A Pilot Study Digital web-based postoperative follow-up form - Remote Monitoring of Pain and Recovery Quality in the Immediate Postoperative Period Using a Digital Health Tool, Pain, Postoperative | Not yet recruiting | Hospital de Base | 213 | 2026-10-01 | 2026-08-31 | |
| Recovery With Virtual Reality for Stress and Pain Preoperative Virtual Reality, Usual Perioperative Care - Preoperative Anxiety, Postoperative Pain | Not applicable | Not yet recruiting | Region Skane | 140 | 2026-09-30 | 2026-07-01 |
| A Study to Compare the Bioavailability of Ondansetron Following Nasal (NS003) and IV Administration in Healthy Adults NS003 Ondansetron HCl microspheres powder for nasal application, Ondansetron Solution for IV infusion 8mg - Chemotherapy-Induced Nausea and Vomiting (CINV), Radiotherapy-induced Nausea and Vomiting (RINV) | Phase 1 | Recruiting | Nasus Pharma | 12 | 2026-09-15 | 2026-10-09 |
| Recovery Trajectories After Propofol-Based Intravenous Anesthesia in Toddlers and Older Children Anesthesia Recovery, Pediatric Anesthesia | Not yet recruiting | Assiut University | 64 | 2026-09-01 | 2026-08-14 | |
| Comparison Between Opioid-Free Anaesthesia Versus Opioid Based Anesthesia in Reduction Postoperative Nausea and Vomiting (PONV)After Thoracoscopic Lung Resection. Opioid Free Anaesthesia, conventential opioid-based anaesthesia (OBA, - PONV | Not applicable | Not yet recruiting | Sohag University | 120 | 2026-09-01 | 2026-09-08 |
| Effect of a Multimodal Antiemetic Protocol on Postoperative Nausea and Vomiting in Patients Undergoing Flap Surgery for Head and Neck Cancer Standard antiemetic and anesthetic protocol, Multimodal antiemetic and anesthetic protocol - Postoperative Nausea and Vomiting | Not applicable | Not yet recruiting | Seoul National University Hospital | 72 | 2026-09-01 | 2026-08-26 |
| Time to First Rescue Antiemetic With Ondansetron Plus Metoclopramide Versus Dexamethasone Plus Metoclopramide for PONV Prophylaxis in Laparoscopic Cholecystectomy ondansetron 4 mg, Dexamethasone (intravenous), Metoclopramide 10mg - Postoperative Nausea and Vomiting | Phase 4 | Recruiting | Faisalabad Medical University | 264 | 2026-09-01 | 2026-09-04 |
| Sleep Quality - Comparing the Effect of Ondansetron or Dexamethasone Given as Routine Prophylaxis Intraoperatively to Prevent Post Operative Nausea and Vomiting (SCORPION) Dexamethasone (IV), Ondansetron iv - Postoperative Sleep Quality, Postoperative Behaviour | Phase 4 | Not yet recruiting | Telethon Kids Institute | 500 | 2026-08-17 | 2026-08-20 |
| Opioid-Free Anesthesia in FESS: A Prospective ERAS Study Dexmedetomidine, Remifentanil - Chronic Sinusitis, Postoperative Pain | Recruiting | Filiz Kaya | 104 | 2026-08-15 | 2026-09-10 | |
| A Randomized Controlled Trial Comparing the Effects of Different Anesthetic Sedatives on PONV in Laparoscopic Cholecystectomy Propofol, Ciprofol, Remimazolam - Cholelithiasis, Postoperative Nausea and Vomiting | Phase 4 | Active not recruiting | Xi'an Aerospace General Hospital | 114 | 2026-08-15 | 2026-10-13 |
| Early Postoperative Pain After Cardiac Surgery Postoperative Nausea and Vomiting (PONV) | Completed | Antalya Training and Research Hospital | 99 | 2026-08-10 | 2026-10-01 | |
| Risk Factors for Postoperative Nausea and Vomiting After Nasal Surgery Under General Anesthesia PONV | Not yet recruiting | Eye & ENT Hospital of Fudan University | 1000 | 2026-08-01 | 2026-08-06 | |
| Application of Multimodal Intervention in the Prevention of Postoperative Nausea and Vomiting After Gynecological Laparoscopic Surgery Amisulpride Injection, Dexamethasone (intravenous), Transcutaneous electrical acupoint stimulation (TEAS) - Nausea and Vomiting, Postoperative | Not applicable | Not yet recruiting | Sir Run Run Shaw Hospital | 212 | 2026-07-01 | 2026-06-08 |
| Aprepitant to Improve Same Day Discharge for TKA Aprepitant Injection, Ondansetron (Zofran), Dexamethasone - PONV | Phase 4 | Not yet recruiting | Endeavor Health | 350 | 2026-07-01 | 2026-06-10 |
| Catheter Redosing of Autonomic Neural Blockade After Sleeve Gastrectomy Bupivacaine 0.5% and Dexamethasone via Temporary Catheter - Pain, Acute Post-Operative, Nausea and Vomiting, Postoperative | Not applicable | Not yet recruiting | Universidad Simón Bolívar | 30 | 2026-06-15 | 2026-06-18 |
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Pain, Postoperative (154) · Vomiting (89) · Nausea (63) · Postoperative Complications (37) · Pain (26) · Agnosia (23) · Emergence Delirium (14) · Patient Satisfaction (11) · Breast Neoplasms (9) · Anxiety Disorders (8) · Obesity, Morbid (8) · Obesity (6) · Pharyngitis (6) · Strabismus (6)
Pathologic Processes (632) · Pathological Conditions, Signs and Symptoms (632) · Signs and Symptoms (632) · Signs and Symptoms, Digestive (631) · Postoperative Complications (595) · Nausea (569) · Vomiting (543) · Neurologic Manifestations (194) · Pain (149) · Nervous System Diseases (58) · Neurobehavioral Manifestations (39) · Mental Disorders (27) · Perceptual Disorders (23) · Neoplasms (20) · Neoplasms by Site (20)
Dexamethasone (103) · Ondansetron (70) · Sodium Chloride (47) · Saline Solution (38) · Aprepitant (34) · Palonosetron (26) · Dexmedetomidine (21) · ramosetron (17) · Calcium Dobesilate (15) · Granisetron (14) · Lidocaine (14) · Bupivacaine (13) · Propofol (13) · Anesthesia, General (11) · Acupuncture Therapy (10)
Assiut University (14) · Yonsei University (11) · Acacia Pharma Ltd (10) · Cairo University (7) · Tanta University (7) · Ankara City Hospital Bilkent (6) · Bezmialem Vakif University (6) · Insel Gruppe AG, University Hospital Bern (6) · Instituto do Cancer do Estado de São Paulo (6) · GlaxoSmithKline (5) · Hvidovre University Hospital (5) · Merck Sharp & Dohme LLC (5) · Pontificia Universidade Catolica de Sao Paulo (5) · Ain Shams University (4) · Khon Kaen University (4)
United States (108) · Turkey (Türkiye) (95) · China (54) · Egypt (40) · South Korea (39) · Brazil (24) · Denmark (21) · Canada (19) · Switzerland (19) · France (15) · Germany (15) · Pakistan (14) · Poland (13) · Thailand (12) · Belgium (8)
Dong-Xin Wang, MD, PhD (3) · Nicolai Bang Foss, Dr.med. (3) · Alejandro Gonzalez-Ojeda, M.D., Ph.D. (2) · Daniel I Sessler, M.D. (2) · Ebba Kihlstedt Pasquier, MD (2) · Eduardo T Moro, Professor (2) · Ellen Andersson, MD, PhD (2) · Gedge D Rosson, MD (2) · He Huang, MD (2) · Jakob Wallden, MD PhD (2) · Lin Cheng, B.S (2) · Moataz M Emara, MD, EDAIC (2)
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