28 completed, 18 unknown, 17 recruiting, 4 not yet recruiting. 16 Not applicable, 10 Phase 2, 9 Phase 1, 6 Phase 3, 3 Phase 4.
Follow Biliary Atresia: new trials by email Literature Review of Biliary Atresia trials Research Report on Biliary Atresia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Tolerability of Enteral NAC in Infants N-Acetylcysteine - Biliary Atresia | Phase 1 | Not yet recruiting | Sanjiv Harpavat | 12 | 2026-10-01 | 2026-03-04 |
| Umbilical Cord Mesenchymal Stem Cell Therapy for Biliary Atresia Umbilical Cord-Mesenchymal Stem Cells (UC-MSC), Kasai Portoenterostomy - Biliary Atresia, Kasai Operation | Phase 1 | Recruiting | Dr Cipto Mangunkusumo General Hospital | 40 | 2026-09-01 | 2026-09-09 |
| Dental Dyschromia and Quality of Life in Early Prolonged Hyperbilirubinemia Questionnaires - Dental Diseases | Recruiting | University Hospital, Toulouse | 120 | 2026-04-07 | 2026-05-12 | |
| The Use of Near-Infrared Fluorescence Cholangiography With Indocyanine Green (ICG) in the Work Up of Neonatal Cholestasis Indocyanine Green - Biliary Atresia, Kasai | Early Phase 1 | Recruiting | University of Alabama at Birmingham | 15 | 2026-01-23 | 2026-02-18 |
| Kasai Portoenterostomy Timing and Outcomes in Biliary Atresia Kasai portoenterostomy - Biliary Atresia | Completed | The Children's Hospital of Zhejiang University School of Medicine | 200 | 2025-12-01 | 2026-02-06 | |
| Cholangitis Definition and Treatment After Kasai Hepatoportoenterostomy for Biliary Atresia: TRACK-BA Study (TRacking Cholangitis Post Kasai in Biliary Atresia) Biliary Atresia, Kasai Portoenterostomy Status, Cholangitis | Not yet recruiting | University Hospital, Geneva | 40 | 2025-10-01 | 2025-08-19 | |
| Stool Card in Biliary Atresia Stool Color Card, Biliary Atresia | Not yet recruiting | Assiut University | 100 | 2025-09-01 | 2025-08-24 | |
| Clinical Outcomes of Early Kasai Surgery With Umbilical Cord MSCs in Biliary Atresia Umbilical Cord-Derived Mesenchymal Stem Cells (UC-MSCs), Kasai Portoenterostomy - Biliary Atresia, Kasai Portoenterostomy | Phase 1 | Not yet recruiting | Universitas Diponegoro | 14 | 2025-06-17 | 2025-06-08 |
| The Dirty Nappy Study Cholestasis in Newborn, Biliary Atresia | Recruiting | Birmingham Women's and Children's NHS Foundation Trust | 5350 | 2025-04-01 | 2026-07-13 | |
| Nutritional Intervention for Biliary Atresia high MCT formula, normal oral intake of the traditional formula - Nutrition Disorder, Infant, Biliary Atresia | Not applicable | Recruiting | Tongji Hospital | 120 | 2025-02-01 | 2025-12-22 |
| Evaluation of the Use of Granulocyte Colony Stimulating Factor (GCSF) in Post Kasai Type 3 Biliary Atresia Granulocyte Colony-Stimulating Factor - Granulocyte Colony-stimulating Factor, Biliary Atresia | Not applicable | Recruiting | National Liver Institute, Egypt | 40 | 2024-12-01 | 2024-12-11 |
| Evaluation of Maralixibat in Pruritus Associated With General Cholestatic Liver Disease (EXPAND) Maralixibat, Placebo - Cholestatic Liver Disease (Except ALGS, PFIC, PBC and PSC) | Phase 3 | Active not recruiting | Mirum Pharmaceuticals, Inc. | 90 | 2024-10-14 | 2026-10-06 |
| Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Obeticholic Acid (OCA) Compared to Placebo in Pediatric Participants With Biliary Atresia, Post-hepatoportoenterostomy OCA, Matching Placebo - Biliary Atresia | Phase 2 / Phase 3 | Terminated | Intercept Pharmaceuticals | 28 | 2024-09-02 | 2026-07-07 |
| Use of Indocyanine Green (ICG) for the Diagnosis of Biliary Atresia Indocyanine Green (ICG) - Biliary Atresia | Phase 1 / Phase 2 | Recruiting | Boston Children's Hospital | 20 | 2024-08-01 | 2026-04-06 |
| ERAS in Choledochal Cyst & Biliary Atresia Enhanced Recovery After Surgery, Post-operative care - Choledochal Cyst Resection, Biliary Atresia, Kasai Portoenterostomy Status | Not applicable | Recruiting | Muhammad Zubair Shoukat | 100 | 2024-07-27 | 2026-07-16 |
| Efficacy of New Post Kasai ILBS Protocol in Biliary Atresia. Kasai Surgery - Biliary Atresia | Unknown | Institute of Liver and Biliary Sciences, India | 100 | 2024-06-06 | 2024-06-11 | |
| Stem Cell Applications in Biliary Atresia Patients Stem Cell, Control - Biliary Atresia, Fibrosis, Liver | Not applicable | Unknown | Necmi Kadıoğlu Hospital | 64 | 2024-06-01 | 2024-09-19 |
| Biliary Atresia Research Network Northeast Biliary Atresia | Completed | Yale University | 320 | 2024-05-06 | 2026-06-25 | |
| Robot-assisted Modified Kasai Portoenterostomy Versus Open Kasai Portoenterostomy for Biliary Atresia robot-assisted modified Kasai portoenterostomy, traditional open Kasai portoenterostomy - Biliary Atresia, Kasai Operation | Unknown | Zunyi Medical College | 60 | 2023-12-21 | 2024-01-23 | |
| Intestinal Microbiome Composition in Infants With Biliary Atresia (BA) Biliary Atresia, Intrahepatic Cholestases | Withdrawn | Children's Hospital Medical Center, Cincinnati | 2023-12-01 | 2025-07-09 |
Showing 20 of 75. Sign in to see all of them.
Cholangitis (8) · Cholestasis (7) · Liver Cirrhosis (6) · Alagille Syndrome (4) · Cholangitis, Sclerosing (4) · Liver Cirrhosis, Biliary (4) · Choledochal Cyst (2) · Fibrosis (2) · Hypertension, Portal (2) · Rare Diseases (2) · 3-Methylglutaconic Aciduria, Type V (1) · Achalasia Addisonianism Alacrimia syndrome (1) · Acrodysostosis (1) · Addison Disease (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (75) · Digestive System Abnormalities (75) · Bile Duct Diseases (74) · Biliary Tract Diseases (74) · Congenital Abnormalities (74) · Digestive System Diseases (74) · Liver Diseases (15) · Pathological Conditions, Signs and Symptoms (13) · Pathologic Processes (12) · Fibrosis (8) · Cholestasis, Intrahepatic (7) · Cholestasis (6) · Cardiovascular Diseases (5) · Abnormalities, Multiple (4) · Cardiovascular Abnormalities (4)
Portoenterostomy, Hepatic (6) · Granulocyte Colony-Stimulating Factor (3) · Acetylcysteine (2) · Blood Specimen Collection (2) · Filgrastim (2) · Immunoglobulins, Intravenous (2) · Indocyanine Green (2) · Meropenem (2) · Methylprednisolone (2) · Prednisolone (2) · Vancomycin (2) · maralixibat (2) · odevixibat (2) · Adrenal Cortex Hormones (1) · Anesthesia, General (1)
Children's Hospital of Fudan University (4) · National Taiwan University Hospital (4) · Arbor Research Collaborative for Health (3) · Tongji Hospital (3) · Vinmec Research Institute of Stem Cell and Gene Technology (3) · Yonsei University (3) · Albireo, an Ipsen Company (2) · Baylor College of Medicine (2) · Children's Hospital Medical Center, Cincinnati (2) · Holterman, Ai-Xuan, M.D. (2) · Institute of Liver and Biliary Sciences, India (2) · Intercept Pharmaceuticals (2) · Mirum Pharmaceuticals, Inc. (2) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (2) · Xinhua Hospital, Shanghai Jiao Tong University School of Medicine (2)
United States (22) · China (18) · Canada (8) · Germany (7) · Taiwan (7) · United Kingdom (7) · France (6) · Vietnam (6) · Egypt (5) · Poland (5) · Turkey (Türkiye) (5) · Australia (4) · Italy (4) · South Korea (4) · Spain (4)
Ed Doo, MD (5) · Averell Sherker, MD (3) · John Magee, MD (3) · Lisa Henn, PhD (3) · Katrina Loh, MD (2) · Liem Nguyen (2) · Lynda Szczech, MD (2) · Mei-Hwei Chang, MD (2) · Ronald Sokol, MD (2) · Avriana Pety Wardani, MD, Sp.BA (1) · Benjamin Shneider, MD (1) · Carsten R Engelmann, MD, OhD (1) · Claus Petersen, Prof. (1) · Danendra Rakha Putra Respati, MD (1) · Erik Prabowo, Dr, MD, M.Si.Med, Sp.B-KBD (1)
PMID 26725209, PMID 29519540, PMID 35391541, PMID 12183720, PMID 21475026, PMID 22732895, PMID 22891232, PMID 22903006, PMID 23054338, PMID 24244109, PMID 24493287, PMID 24794368, PMID 25015575, PMID 25419594, PMID 25534776, PMID 25564820, PMID 25681196, PMID 26756872, PMID 30244988, PMID 30488647, PMID 30664564, PMID 32633158, PMID 33664005, PMID 34310436, PMID 34817690, PMID 34842600, PMID 35207269, PMID 35287722, PMID 36602550, PMID 37471052, PMID 37678274, PMID 38055647, PMID 38189999, PMID 38994513, PMID 39526563, PMID 39568009, PMID 40250622, PMID 40489761, PMID 40907882, PMID 42165317
U01DK062456 (5), U01DK062436 (3), U01DK062445 (3), U01DK062452 (3), U01DK062453 (3), U01DK062466 (3), U01DK062470 (3), U01DK062481 (3), U01DK062497 (3), U01DK062500 (3), U01DK062503 (3), U01DK084536 (3), U01DK084538 (3), U01DK084575 (3), U01DK103135 (3)