Desflurane: Clinical Trials

165 trials of Desflurane, newest first

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121 completed, 22 unknown, 9 recruiting, 8 withdrawn. 82 Not applicable, 54 Phase 4, 9 Phase 3, 7 Phase 2, 2 Phase 1.

By phase and status

PhaseTrialsStatus
Not applicable82Completed 60, Unknown 10, Recruiting 5, Withdrawn 4, Not yet recruiting 2, Terminated 1
Phase 454Completed 37, Unknown 8, Withdrawn 4, Recruiting 3, Not yet recruiting 1, Terminated 1
Phase 39Completed 9
Phase 27Completed 7
Phase 12Completed 2
Early Phase 11Unknown 1

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Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Swap Anesthetic Versus Continuous Desflurane in Adults Undergoing Bariatric Surgery
Desflurane, Sevoflurane-Desflurane - Obesity, Bariatric Surgery
Phase 4Not yet recruitingClínica Dávila822026-08-032026-08-05
Comparison of the Effects of Sevoflurane and Desflurane on Optic Nerve Sheath Diameter During Laparoscopic Surgery
Sevoflurane, Desflurane - Intracranial Pressure, Laparoscopic Surgery
Not applicableCompletedMedipol University632026-04-152026-08-04
Comparison of Sevoflurane and Desflurane on ANI in Patients Undergoing General Anesthesia: a Prospective Randomized Controlled Study
Desflurane, Sevoflurane - General Anesthesia
Not applicableNot yet recruitingPusan National University Yangsan Hospital802026-04-012026-04-06
Low-Flow Sevoflurane and Desflurane Anesthesia in Laparoscopic Cholecystectomy
Sevoflurane, Desflurane - Laparoscopic Cholecystectomy, Postoperative Sore Throat
Not applicableCompletedKayseri City Hospital802026-03-202026-08-25
Effect of Sevoflurane vs Desflurane on Mechanical Power in Laparoscopic Cholecystectomy
Sevoflurane, Desflurane - Perioperative Respiratory Mechanics
Not applicableCompletedKonya City Hospital1382026-03-092026-09-15
Comparison of the Metabolomic Effects of Sevoflurane and Desflurane Anesthesia in Laparoscopic Cholecystectomy
Sevoflurane, Desflurane - Sevoflurane Desflurane, Metabolomic Effect
Not applicableNot yet recruitingHarran University802026-02-012026-02-23
DEXDES Trial: Dexmedetomidine-Desflurane Combination in Laparoscopic Colectomy
Dexmedetomidine + Desflurane, Desflurane + Normal Saline - Colorectal Neoplasms
Not applicableRecruitingTam Anh Research Institute402025-12-012025-12-30
Effect of Combined Intravenous-Inhalational Anesthesia (CIVIA) on Postoperative Recovery Patterns.
Sevofluorane, Desflurane, Total Intravenous Anesthesia(TIVA) - Postoperative Recovery, Inhalation Anesthesia
Phase 4CompletedKocaeli City Hospital2102025-07-232026-10-27
Low-Flow Desflurane vs Sevoflurane: Impact on Physiology and Recoveryand Recovery Profiles in Adult ENT Surgery
Sevoflurane, Desflurane - Anesthesia, General
Not applicableCompletedHarran University402025-06-102026-02-27
Effect of Volatile- Based Versus Total Intravenous Anesthesia on Brain Homeostasis and Neurocognitive Outcome
Sevoflurane, Desflurane - Brain Edema Caused by Drugs, Cerebral Oxygenation
Phase 4RecruitingGeorgia Tsaousi842025-05-122025-10-01
Effects of Sevoflurane Versus Desflurane Anesthesia Under Protective Mechanical Ventilation for Robotic Assisted Surgery
Sevoflurane (Volatile Anesthetic), Desflurane (volatile anesthetic) - Respiratory Mechanics, Intraoperative
Not applicableRecruitingNational and Kapodistrian University of Athens502025-05-012025-12-26
Inhalational Agents Versus Dexmedetomidine for Maintenance of General Anesthesia
Dexmedetomidine + Remifentanil, Desflurane + Remifentanil - Ureterorenoscopic Lithotripsy, Transurethral Resection of the Bladder
Not applicableRecruitingBakirkoy Dr. Sadi Konuk Research and Training Hospital1502024-10-012026-01-23
Effects of Sevoflurane vs Desflurane on Early Recovery and Cognitive Function in Elderly Patients Undergoing Scheduled Non-Cardiac Surgery
Sevoflurane, Desflurane - Early Recovery in Elderly Patients, Cognitive Function
Phase 3CompletedHopital Charles Nicolle812024-09-152026-08-06
Anesthesia and Non-small Cell Lung Cancer Recurrence
Propofol, Inhaled anesthetics - Non-small Cell Lung Cancer, Surgery
Phase 4RecruitingSamsung Medical Center53842024-08-052026-04-20
Effect of Desflurane v/s Propofol on the Optic Nerve Sheath Diameter
Desflurane, Propofol (Group P) - Propofol Target-controlled Infusion, Desflurane
Phase 4CompletedAll India Institute of Medical Sciences1462024-01-102026-01-22
Evaluation of the Stress Response in Anesthesia Use Inhalation Anesthetic (Desflurane) Versus TIVA for Bariatric Surgery
opioid free anesthesia, Opiod Free Anesthesia with TCI ELEVELD - Opioid Use, Bariatric Surgery Candidate
Not applicableRecruitingG.Gennimatas General Hospital702024-01-102026-05-06
Desflurane Versus Isoflurane for Speeding Postanesthetic Recovery and Hospital Discharge
Desflurane, Isoflurane - Surgery
Not applicableWithdrawnThe Cleveland Clinic2023-12-082026-03-05
Comparison of Desflurane, Sevoflurane, and Total Intravenous Anesthesia in Ear Surgery Under Controlled Hypotension
Desflurane, Sevoflurane, Remifentanil - Postoperative Cognitive Dysfunction (POCD), Controlled Hypotension for Nasal Surgeries
Not applicableCompletedDr. Lutfi Kirdar Kartal Training and Research Hospital692023-12-012026-08-28
The Anesthesia Effects of Dexmedetomidine Combined With Desflurane or Propofol in Lobectomy
Dexmedetomidine and propofol, Dexmedetomidine and desflurane - Anesthesia Recovery Period, Postoperative Complications
Not applicableUnknownThe Second Affiliated Hospital of Chongqing Medical University1202023-10-212024-03-13
Impact of Desflurane and Sevoflurane on Postoperative Delirium in Elderly Patients
Desflurane, Sevoflurane - Delirium, Postoperative Cognitive Dysfunction
Not applicableUnknownWest China Hospital8902023-09-102024-06-04

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Conditions studied

Obesity (9)  ·  Emergence Delirium (8)  ·  Postoperative Cognitive Complications (5)  ·  Delirium (4)  ·  Respiratory Aspiration (4)  ·  Cognitive Dysfunction (3)  ·  Lung Neoplasms (3)  ·  Pain, Postoperative (3)  ·  Postoperative Complications (3)  ·  Postoperative Nausea and Vomiting (3)  ·  Acute Kidney Injury (2)  ·  Arthritis (2)  ·  Breast Neoplasms (2)  ·  Colorectal Neoplasms (2)  ·  Delayed Emergence from Anesthesia (2)

Sponsors

Seoul National University Hospital (10)  ·  Yonsei University (10)  ·  Kangbuk Samsung Hospital (6)  ·  Beijing Tiantan Hospital (3)  ·  Theodor Bilharz Research Institute (3)  ·  Chosun University Hospital (2)  ·  Chung-Ang University Hospital (2)  ·  Harran University (2)  ·  Medical University of Vienna (2)  ·  National Taiwan University Hospital (2)  ·  National and Kapodistrian University of Athens (2)  ·  Ohio State University (2)  ·  Post Graduate Institute of Medical Education and Research, Chandigarh (2)  ·  RWTH Aachen University (2)  ·  Ruhr University of Bochum (2)

Countries

South Korea (36)  ·  United States (17)  ·  Turkey (Türkiye) (14)  ·  China (13)  ·  Egypt (7)  ·  Greece (6)  ·  India (6)  ·  Japan (6)  ·  Malaysia (4)  ·  Switzerland (4)  ·  Australia (3)  ·  France (3)  ·  Germany (3)  ·  Taiwan (3)  ·  Thailand (3)

Top investigators

Kyoungho Ryu, M.D. (4)  ·  Amitabh Dutta, MD (2)  ·  Goverdhan D Puri, MD, PhD (2)  ·  Hemant Bhagat, DM (2)  ·  Jonathan P Wanderer, MD, MPhil (2)  ·  Ki Tae Jung, M.D. (2)  ·  Kyoung-Ho Ryu, M.D. (2)  ·  Nitin Sethi, DNB (2)  ·  Thomas Weber, PhD (2)  ·  Abla El Hadidy, PhD (1)  ·  Aikaterini Melemeni, Professor (1)  ·  Ailin Luo, Doctor (1)

Results publications

PMID 11193758, PMID 12883404, PMID 14501224, PMID 15145114, PMID 16517337, PMID 17203512, PMID 17573389, PMID 17668184, PMID 18219153, PMID 18786243, PMID 19411668, PMID 19602953, PMID 19636971, PMID 19672164, PMID 19713279, PMID 19833258, PMID 21372274, PMID 21463263, PMID 21733178, PMID 22345176, PMID 22851612, PMID 23695172, PMID 24643920, PMID 24883378, PMID 25906190, PMID 26107449, PMID 26210907, PMID 26335917, PMID 26830645, PMID 27065094, PMID 27247511, PMID 28100177, PMID 28374886, PMID 29223575, PMID 29916859, PMID 30336856, PMID 30888743, PMID 31111072, PMID 31620921, PMID 31691253, PMID 32149764, PMID 32854613, PMID 32915370, PMID 32958203, PMID 33238043, PMID 33528788, PMID 33564684, PMID 33845761, PMID 33849618, PMID 34132704

NIH funding

2009 (3), 2016 (1), 2017 (1), 2019 (1)