9 completed, 4 recruiting, 4 unknown, 3 terminated. 21 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 21 | Completed 9, Recruiting 4, Unknown 4, Terminated 3, Not yet recruiting 1 |
Follow Tonsillitis: new trials by email Literature Review of Tonsillitis trials Research Report on Tonsillitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Single Dose of Intravenous Penicillin as an Adjunct to Oral Penicillin in the Treatment of Acute Tonsillitis, Peritonsillar Phlegmon, and Peritonsillar Abscess Benzylpenicillin, Isotonic NaCl (Placebo) - Acute Tonsillitis, Peritonsillar Abscess | Phase 4 | Not yet recruiting | Tejs Ehlers Klug | 154 | 2026-10-01 | 2026-10-26 |
| Trimethoprim-sulfamethoxazole vs. Clindamycin for the Treatment of Children With Invasive MRSA Infections Trimethoprim Sulfamethoxazole - Methicillin Resistant Staphylococcus Aureus, Osteomyelitis Acute | Phase 4 | Recruiting | Indiana University | 100 | 2025-05-20 | 2026-07-29 |
| Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia Methadone, Fentanyl/Hydromorphone - Pain, Postoperative, Tonsillar Hypertrophy | Phase 4 | Recruiting | Duke University | 440 | 2024-11-21 | 2025-12-05 |
| Opioid-Free Anesthetic for Tonsillectomy Ketorolac, Dexmedetomidine, Morphine - Anesthesia, Opioid Use | Phase 4 | Terminated | Children's Hospital of Philadelphia | 35 | 2020-07-22 | 2024-12-20 |
| Sore Throat in Primary Care - a Comparison of Phenoxymethylpenicillin and No Antibiotic Treatment Phenoxymethylpenicillin, No antibiotic treatment - Sore Throat, Tonsillitis | Phase 4 | Recruiting | Katarina Hedin | 260 | 2019-09-09 | 2024-12-04 |
| Comparison of Bizact With Electroscissor for Tonsillectomy tonsillar dissection - Tonsillar Hypertrophy, Tonsillitis | Phase 4 | Unknown | Oslo University Hospital | 60 | 2019-02-20 | 2019-02-26 |
| Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy Gabapentin - Tonsillitis, Tonsillectomy | Phase 4 | Recruiting | Children's Healthcare of Atlanta | 50 | 2018-07-31 | 2019-07-24 |
| Perioperative Tonsillectomy Protocol Development Acetaminophen, Low-dose Dexamethasone, Placebo Oral Tablet - Tonsillitis | Phase 4 | Unknown | London Health Sciences Centre | 60 | 2018-03-01 | 2021-02-18 |
| Study of 5 and 10 Days Treatment With Penicillin Against Sore Throat Caused by Streptococci Phenoxymethylpenicillin - Tonsillitis | Phase 4 | Completed | Ass. Prof. Katarina Hedin | 433 | 2015-09-01 | 2018-11-14 |
| EXPAREL® for Pain After Tonsillectomy Liposomal Bupivacaine - Tonsillectomy, Tonsillitis | Phase 4 | Completed | Mayo Clinic | 39 | 2015-05-01 | 2017-07-14 |
| The Effect of Dexmedetomidine on Airway Complications After Deep or Awake Extubation Normal Saline, Dexmedetomidine - Adenotonsillar Hypertrophy, Obstructive Sleep Apnea | Phase 4 | Terminated | Massachusetts Eye and Ear Infirmary | 92 | 2015-03-01 | 2020-04-09 |
| Post-operative Pain Control After Pediatric Adenotonsillectomy Ibuprofen, Hydrocodone-Acetaminophen - Recurrent Tonsillitis, Obstructive Sleep Apnea | Phase 4 | Terminated | Emory University | 45 | 2014-11-01 | 2018-04-25 |
| Continuous Intravenous Sufentanil Infusion for Postoperative Pain Management Following Tonsillectomy or Adeno-tonsillectomy in Children continuous intravenous sufentanil 0.02μg•kg-1•h-1 infusion, continuous intravenous sufentanil 0.03μg•kg-1•h-1 infusion, continuous intravenous sufentanil 0.04μg•kg-1•h-1 infusion - Sleep Breathing Disorders, Tonsillitis | Phase 4 | Unknown | Jin Ni | 60 | 2014-09-01 | 2014-09-30 |
| Acetaminophen's Efficacy For Post-operative Pain IV acetaminophen, PO acetaminophen - Tonsillitis, Airway Obstruction | Phase 4 | Completed | Kaveh Aslani, MD | 41 | 2012-09-01 | 2017-06-08 |
| A Comparison of Postoperative Tramadol Versus Acetaminophen With Codeine in Children Undergoing Tonsillectomy Codeine with acetaminophen, Tramadol suspension - Tonsillitis, Pain | Phase 4 | Completed | Children's Hospitals and Clinics of Minnesota | 84 | 2011-01-01 | 2014-04-17 |
| Efficacy of Tinoridine in Treating Pain and Inflammation in Adults Tinoridine HCl, Placebo - Pain, Inflammation | Phase 4 | Completed | Takeda | 342 | 2010-11-01 | 2012-01-12 |
| Recurrent Throat Infections and Tonsillectomy Tonsillectomy, no intervention - Tonsillitis, Pharyngitis | Phase 4 | Completed | Oulu University Hospital | 87 | 2007-11-01 | 2012-04-19 |
| Randomized Controlled Study of Plasmaknife Tonsillectomy Versus Monopolar Tonsillectomy Plasmaknife, Monopolar - Obstructive Tonsillar Hypertrophy, Tonsillitis | Phase 4 | Unknown | Children's Hospital of Michigan | 100 | 2007-05-01 | 2007-04-27 |
| Dexmedetomidine for Immediate Perioperative Analgesia in Pediatric Patients Undergoing Tonsillectomy Fentanyl, Dexmedetomidine - Tonsillitis | Phase 4 | Completed | Children's National Research Institute | 101 | 2005-01-01 | 2021-03-23 |
| Placebo and Active Controlled Study to Compare the Efficacy of Aspirin and Paracetamol in Treatment of Sore Throat Associated With a Common Cold Acetylsalicylic acid (Aspirin, BAYE4465), Paracetamol, Placebo - Common Cold, Pharyngitis | Phase 4 | Completed | Bayer | 508 | 2003-11-01 | 2014-12-11 |
Showing 20 of 21. Sign in to see all of them.
Pharyngitis (4) · Pain (2) · Pain, Postoperative (2) · Peritonsillar Abscess (2) · Sleep Apnea Syndromes (2) · Sleep Apnea, Obstructive (2) · Agnosia (1) · Airway Obstruction (1) · Arthritis, Infectious (1) · Common Cold (1) · Deglutition Disorders (1) · Drug-Related Side Effects and Adverse Reactions (1) · Inflammation (1) · Mastoiditis (1)
Infections (21) · Otorhinolaryngologic Diseases (21) · Pharyngeal Diseases (21) · Respiratory Tract Diseases (21) · Respiratory Tract Infections (21) · Stomatognathic Diseases (21) · Pharyngitis (17) · Neurologic Manifestations (6) · Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (6) · Nervous System Diseases (4) · Respiration Disorders (4) · Apnea (3) · Dyssomnias (3) · Pathologic Processes (3)
Acetaminophen (4) · Dexmedetomidine (3) · Fentanyl (3) · Penicillin V (2) · Amoxicillin (1) · Aspirin (1) · Azithromycin (1) · Codeine (1) · Dexamethasone (1) · Economics (1) · Gabapentin (1) · Hydromorphone (1) · Ibuprofen (1) · Ketorolac (1) · Ketorolac Tromethamine (1)
Ass. Prof. Katarina Hedin (1) · Bayer (1) · Children's Healthcare of Atlanta (1) · Children's Hospital of Michigan (1) · Children's Hospital of Philadelphia (1) · Children's Hospitals and Clinics of Minnesota (1) · Children's National Research Institute (1) · Duke University (1) · Emory University (1) · Indiana University (1) · Jin Ni (1) · Katarina Hedin (1) · Kaveh Aslani, MD (1) · London Health Sciences Centre (1) · Massachusetts Eye and Ear Infirmary (1)
United States (11) · Sweden (2) · Canada (1) · China (1) · Denmark (1) · Finland (1) · France (1) · Indonesia (1) · Norway (1) · United Kingdom (1)
Aila Kristo, MD (1) · Anthony Sheyn, MD, FACS (1) · Christina Calamaro, PhD, CPNP-PC (1) · Daniel L Price, MD (1) · David Madgy (1) · James Wood, MD (1) · Jin Ni, M.D. (1) · Josee Paradis, MD (1) · Julia C Finkel, MD (1) · Katarina Hedin, Ass Prof (1) · Katarina Hedin, MD PhD (1) · Kaveh Aslani, MD (1) · Lisa M. Einhorn, MD (1) · Makara Cayer, MD (1)
PMID 21461792, PMID 23549975, PMID 31585944, PMID 36368940
2015 (1), 2019 (1), R01HD114678 (1)