483 completed, 143 recruiting, 50 terminated, 37 active not recruiting. 373 Not applicable, 111 Phase 2, 56 Phase 1, 35 Phase 3, 29 Phase 4.
Follow Children's Hospital of Philadelphia: new trials by email
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Development of a Provider-Focused Intervention to Improve Health Outcomes in Pediatric Sickle Cell Disease Individuation and Perspective-Taking (IPT), pediatric SCD pain management education session - Sickle Cell Disease, Sickle Cell Anemia in Children | Not applicable | Not yet recruiting | Connecticut Children's Medical Center | 30 | 2027-09-01 | 2026-04-29 |
| Technology Knowledge Optimization for Type 1 Diabetes in Schools TeKnO T1D curriculum - Type 1 Diabetes (T1D) | Not applicable | Not yet recruiting | University of Pittsburgh | 86 | 2027-02-01 | 2026-03-19 |
| Combination of Avutometinib and Defactinib for Treatment of Relapsed, Refractory, Metastatic, or Unresectable Malignant Peripheral Nerve Sheath Tumor avutometinib capsule + defactinib tablet - MPNST (Malignant Peripheral Nerve Sheath Tumor) | Phase 2 | Not yet recruiting | Girish Dhall, MD | 23 | 2027-01-01 | 2026-08-04 |
| EoE Food Test Pilot Study Assay directed diet change - Eosinophilic Esophagitis Caused by Food (Disorder) | Not applicable | Not yet recruiting | Children's Hospital of Philadelphia | 50 | 2027-01-01 | 2026-03-16 |
| Postpartum Care in the NICU Multi-Site Postpartum Doula Support in the NICU - Postpartum, Postpartum Depression (PPD) | Not applicable | Not yet recruiting | Children's Hospital of Philadelphia | 756 | 2027-01-01 | 2026-10-14 |
| AVTX-801 D-galactose Supplementation in SLC35A2-CDG AVTX-801, Placebo - SLC35A2-CDG - Solute Carrier Family 35 Member A2 Congenital Disorder of Glycosylation | Phase 2 | Not yet recruiting | Eva Morava-Kozicz | 10 | 2027-01-01 | 2026-06-29 |
| Efficacy of Mirdametinib Alone or Combination With Radiotherapy for Germline and Sporadic NF1-Altered High-Grade Glioma mirdametinib with radiation, mirdametinib - Neurofibromatosis 1 (NF1) | Phase 2 | Not yet recruiting | University of Alabama at Birmingham | 55 | 2027-01-01 | 2026-10-05 |
| Postpartum Care in the NICU Multi-Site Breastfeeding NICU-informed postpartum doula support - Postpartum Complication, Postpartum | Not applicable | Not yet recruiting | Children's Hospital of Philadelphia | 640 | 2027-01-01 | 2026-10-19 |
| Crisis Interventions for Pediatric Providers - Autism Version Safety Planning Intervention, Crisis Interventions for Pediatric Providers - Autism version (CIPP-A) - Autism, Suicide Prevention | Not applicable | Not yet recruiting | Children's Hospital Los Angeles | 70 | 2026-12-01 | 2026-04-13 |
| Trial of a Nurse-Led Firearm Safety Intervention in the Pediatric Inpatient Setting Adapted S.A.F.E. Firearm, Implementation bundle - Firearm Safety, Suicide | Not applicable | Not yet recruiting | University of Pennsylvania | 7200 | 2026-12-01 | 2026-04-13 |
| Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG 18F-Fluciclovine - Glioma, Low-grade Glioma | Early Phase 1 | Recruiting | Children's Hospital of Philadelphia | 30 | 2026-11-29 | 2026-09-22 |
| 25BT056: Basket Study of Viral Cytotoxic T Lymphocytes Virus-Specific Cytotoxic T Lymphocytes (vCTLs) - EBV Viremia, CMV Viremia | Early Phase 1 | Not yet recruiting | Children's Hospital of Philadelphia | 35 | 2026-11-01 | 2026-10-14 |
| CEUS Evaluation of Hydrocephalus in Neonates and Infants Sulfur Hexafluoride Lipid Type A Microspheres 25 mg Injection Powder for Suspension [LUMASON] - Hydrocephalus in Infants, Hydrocephalus Acquired | Phase 2 | Recruiting | Children's Hospital of Philadelphia | 20 | 2026-10-15 | 2026-09-16 |
| Evaluating the Efficacy and Safety of D-galactose in PGM1-CDG (AVTX-801) AVTX-801, Placebo - PGM1-CDG - Phosphoglucomutase 1-Related Congenital Disorder of Glycosylation | Phase 2 | Not yet recruiting | Eva Morava-Kozicz | 8 | 2026-10-01 | 2026-03-16 |
| Pilot Study of a Modified Safety Planning Intervention for Elementary School-Aged Children - Main Study Child - Safety Planning Intervention, C-SPI+ecological momentary assessment - Suicidal Ideation, Suicidal Behaviors | Not applicable | Enrolling by invitation | Columbia University | 90 | 2026-09-09 | 2026-09-09 |
| 26DT052; Scaling Busulfan Dose to Body Surface Area in Children Busulfan (BU) - Busulfan Pharmacokinetic Analysis, Busulfan Dosing | Phase 1 | Not yet recruiting | Children's Hospital of Philadelphia | 38 | 2026-09-01 | 2026-08-28 |
| The Social Needs Assistance for Hospitalized Kids Trial Active Assistance by Navigators, Passive Referral - Social Needs, Health-Related Social Needs | Not applicable | Not yet recruiting | University of California, San Francisco | 1880 | 2026-09-01 | 2026-10-20 |
| Bilevel Positive Airway Pressure (BPAP) for Severe Asthma Bilevel positive airway pressure ventilation - Pediatric Asthma, Acute Asthma | Not applicable | Recruiting | Columbia University | 36 | 2026-08-31 | 2026-08-18 |
| Observational Approach Versus Surgical Intervention for Stones Surgery, Observation - Nephrolithiasis, Kidney Stone | Not applicable | Recruiting | Children's Hospital of Philadelphia | 1658 | 2026-08-17 | 2026-10-15 |
| Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas Selumetinib + ZEN-3694 ± Durvalumab - MPNST, NF1 | Phase 2 | Recruiting | University of Alabama at Birmingham | 41 | 2026-08-04 | 2026-08-24 |
Showing 20 of 800. Sign in to see all of them.
Neoplasms (21) · Depression (19) · Cystic Fibrosis (18) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (16) · Autism Spectrum Disorder (15) · Anemia, Sickle Cell (14) · Attention Deficit Disorder with Hyperactivity (14) · Premature Birth (14) · Asthma (12) · Bronchopulmonary Dysplasia (12) · Autistic Disorder (11) · Brain Concussion (11) · Heart Arrest (11) · Heart Defects, Congenital (11) · Obesity (11)
Saline Solution (6) · Sirolimus (6) · Cholecalciferol (5) · Dexmedetomidine (5) · Educational Status (5) · Exercise (5) · Methods (5) · Methotrexate (5) · Standard of Care (5) · Surveys and Questionnaires (5) · Blood Specimen Collection (4) · Bupivacaine (4) · Cognitive Behavioral Therapy (4) · Continuous Positive Airway Pressure (4) · Cyclophosphamide (4)
United States (747) · Canada (40) · Australia (22) · United Kingdom (13) · Italy (10) · Spain (7) · Brazil (6) · India (6) · Germany (5) · Switzerland (5) · Netherlands (4) · Singapore (4) · Sweden (4) · China (3) · Colombia (3)
Timothy Olson, MD, PhD (7) · Virginia Stallings, MD (7) · Alexander G Fiks, MD, MSCE (5) · Andrea Kelly, MD, MSCE (5) · Eva Morava-Kozicz, MD, PhD (5) · Peter Szilagyi, MD (5) · Rhonda Boyd, PhD (5) · Theodore Laetsch, MD (5) · Girish Dhall, MD (4) · James Guevara, MD, MPH (4) · Jeffrey S Gerber, MD, PhD (4) · Lindsey Albenberg, DO (4) · Mitchell S Cairo, MD (4) · Nancy Kassam-Adams, PhD (4) · Vinay Nadkarni, MD (4)
PMID 36094829, PMID 30808770, PMID 33331662, PMID 33981997, PMID 35710520, PMID 37380625, PMID 37844519, PMID 37983082, PMID 38033276, PMID 39382077, PMID 42376265, PMID 42602550, PMID 10417280, PMID 11867979, PMID 12820840, PMID 16126743, PMID 16520452, PMID 16814942, PMID 17236890, PMID 17438241, PMID 17652648, PMID 17765329, PMID 17895314, PMID 18414145, PMID 18544020, PMID 18809946, PMID 18946302, PMID 19208097, PMID 19387313, PMID 19556464, PMID 19593252, PMID 19660971, PMID 19772971, PMID 19786448, PMID 19914908, PMID 19953081, PMID 20032810, PMID 20053789, PMID 20083693, PMID 20215934, PMID 20231667, PMID 20338795, PMID 20375405, PMID 20409628, PMID 20566609, PMID 20666584, PMID 21104896, PMID 21154482, PMID 21245476, PMID 21254193
R01CA202261 (6), P50MH115838 (4), U19HD089881 (4), R01DC011287 (3), U54NS065712 (3), UL1TR001878 (3), K23HD102560 (2), K23MH119976 (2), R01AR083552 (2), R01AT005531 (2), R01HD071981 (2), R01HL090615 (2), R01HL147879 (2), R01HL173600 (2), R21HG011912 (2)