4866 completed, 1559 unknown, 882 recruiting, 555 terminated. 4232 Not applicable, 754 Phase 2, 517 Phase 3, 458 Phase 4, 404 Phase 1.
Follow Respiration Disorders: new trials by email Literature Review of Respiration Disorders trials Research Report on Respiration Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PAP Systems External Clinical Studies (ECS) PAP System A (with Amalfi) then PAP System B (with CLA11), PAP System B (with CLA11) then PAP System A (with Amalfi) - Obstructive Sleep Apnea | Not applicable | Not yet recruiting | ResMed | 30 | 2028-08-01 | 2026-04-24 |
| Acoustic Resonance Therapy for Treating Empty Nose Syndrome Personalized ART, Non-personalized ART - Empty Nose Syndrome, Nasal Obstruction | Not applicable | Not yet recruiting | Stanford University | 40 | 2028-07-01 | 2025-10-10 |
| Adiposity Distribution in Acute Respiratory Failure PEEP Titration Using Electrical Impedance Tomography (EIT), Body Positioning: Supine and Prone - Acute Hypoxemic Respiratory Failure, Obesity | Not applicable | Not yet recruiting | Maurizio F. Cereda, MD | 80 | 2028-01-01 | 2025-06-13 |
| Chronic COUGH Management in Interstitial Lung DisEase Non-pharmacological cough control therapy, Healthy lifestyle - Interstitial Lung Disease, Chronic Cough | Not applicable | Not yet recruiting | Aveiro University | 60 | 2027-12-20 | 2025-01-20 |
| Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 6 of 7) Visible light exposure - Exposure to Man-made Visible Light | Not applicable | Not yet recruiting | University of Bern | 50 | 2027-12-01 | 2026-01-14 |
| Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 5 of 7) Visible light exposure - Exposure to Man-made Visible Light | Not applicable | Not yet recruiting | University of Bern | 50 | 2027-12-01 | 2026-01-14 |
| Optimizing Dysphagia Treatment Delivery in Acute Care: A Hybrid Efficacy Implementation Trial Expiratory muscle strength training (EMST), Standard of Care Dysphagia Treatment, Intensive Dysphagia Treatment - Dysphagia, Critical Illness | Not applicable | Not yet recruiting | Vanderbilt University Medical Center | 120 | 2027-07-01 | 2026-10-14 |
| Calcitonin Gene-related Peptide Antibody in Acute Mountain Sickness Fremanezumab 225 Mg/1.5 mL Subcutaneous Solution, Placebo - Acute Mountain Sickness | Phase 4 | Not yet recruiting | Insel Gruppe AG, University Hospital Bern | 30 | 2027-06-01 | 2026-07-01 |
| Multicentric, Randomized Study to Assess Safety and Efficacy of Centhaquine in Patients With ARDS Normal Saline, Centhaquine - Acute Respiratory Distress Syndrome (ARDS) | Phase 2 | Not yet recruiting | Pharmazz, Inc. | 80 | 2027-05-01 | 2026-09-17 |
| Quantification of Inspiratory Effort Through Nasal Pressure in Patients Undergoing Weaning From Invasive Mechanical Ventilation and Correlation With Clinical Outcomes Nasal pressure assessment - Respiratory Failure | Not yet recruiting | University of Modena and Reggio Emilia | 175 | 2027-05-01 | 2025-04-25 | |
| TORCH-LATAM-003: Regional Advanced-Therapy Pathways for Congenital Heart Disease TORCH Congenital Advanced Therapies Pathway (TORCH-CATP) - Congenital Heart Disease, Advanced Heart Failure | Not applicable | Not yet recruiting | CardioVision International Tech, S.A.S. de C.V. | 360 | 2027-03-30 | 2026-10-13 |
| KPAP vs EPR for Efficacy APAP + KPAP, APAP + EPR - Obstructive Sleep Apnea | Not applicable | Not yet recruiting | SleepRes Inc. | 24 | 2027-03-01 | 2026-08-04 |
| To Evaluate the Safety and Potential Therapeutic Activity of JadiCell™, an Investigational Umbilical Cord-Derived Mesenchymal Stem Cell Therapy, in Patients Diagnosed With Acute Respiratory Distress Syndrome (ARDS). Subjects in the UC-MSC treatment group will receive two intravenous infusions (at day 0 and 3) of 100 million UC-MSC., Controls will receive two infusions of vehicle solution. - Acute Respiratory Distress Syndrome | Phase 3 | Not yet recruiting | Breathe Biologics, Inc. | 128 | 2027-03-01 | 2026-10-01 |
| Study to Examine the Effect of Silicone Mouth Tape on Snoring and Mild Sleep Apnea. Mouth Tape - Mild Obstructive Sleep Apnea, Snoring | Phase 2 | Recruiting | Johns Hopkins University | 100 | 2027-03-01 | 2026-06-23 |
| Automated vs Manual Polysomnography Scoring in Adults With Obstructive Sleep Apnea Polysomnographic Scoring (Automated vs. Manual) - Obstructive Sleep Apnea | Not yet recruiting | Ain Shams University | 50 | 2027-02-01 | 2026-09-23 | |
| Speed of Lung Inflation During Ventilation of Extremely Preterm Infants Long PRT, Short PRT - Respiratory Distress Syndrome, Newborn, Respiratory Distress Syndrome in Premature Infant | Not applicable | Not yet recruiting | Murdoch Childrens Research Institute | 68 | 2027-02-01 | 2026-06-24 |
| Endoscopic Treatment Informed consent, Eligibility criteria check, Randomisation - Stenoses, Dyspnea | Not applicable | Not yet recruiting | University Hospital, Toulouse | 96 | 2027-01-01 | 2026-07-27 |
| The NEU - CAP Trial Local standard care of monitoring non-invasive ventilation, CO₂-guided Non-Invasive Ventilation - Infant, Premature, Diseases, Birth, Preterm | Not applicable | Not yet recruiting | Leiden University Medical Center | 1860 | 2027-01-01 | 2026-08-10 |
| ER-VISION-AI Study Generative Pre-trained Transformer (GPT)-assisted multimodal visual language model (VLM) diagnostic support, Conventional emergency department diagnostic evaluation - Chest Pain, Dyspnea | Not applicable | Not yet recruiting | Ewha Womans University Mokdong Hospital | 1000 | 2027-01-01 | 2026-07-27 |
| A Stepped Intervention for Coping With Dyspnea in Patients With Lung Cancer-Phase A (Open Pilot) INSPIRE - Dyspnea, Lung Cancer (Diagnosis) | Not applicable | Not yet recruiting | Massachusetts General Hospital | 10 | 2027-01-01 | 2026-07-29 |
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Sleep Apnea, Obstructive (2155) · Respiratory Insufficiency (1343) · Respiratory Distress Syndrome (1340) · Sleep Apnea Syndromes (1078) · Respiratory Aspiration (959) · Dyspnea (880) · Pulmonary Disease, Chronic Obstructive (525) · COVID-19 (417) · Cough (411) · Apnea (260) · Hypoxia (255) · Heart Failure (227) · Premature Birth (215) · Altitude Sickness (212)
Respiratory Tract Diseases (8860) · Pathological Conditions, Signs and Symptoms (4327) · Nervous System Diseases (3420) · Dyssomnias (2960) · Sleep Disorders, Intrinsic (2954) · Sleep Wake Disorders (2871) · Apnea (2861) · Signs and Symptoms (2858) · Lung Diseases (2756) · Pathologic Processes (2236) · Signs and Symptoms, Respiratory (2199) · Sleep Apnea Syndromes (1859) · Infections (982) · Cardiovascular Diseases (850)
Continuous Positive Airway Pressure (296) · Noninvasive Ventilation (81) · Standard of Care (74) · Sodium Chloride (65) · Polysomnography (64) · Saline Solution (61) · Exercise (56) · Acetazolamide (55) · Propofol (54) · Dexamethasone (45) · Prone Position (45) · Surveys and Questionnaires (45) · Blood Specimen Collection (44) · Dexmedetomidine (42) · Occlusal Splints (41)
Assistance Publique - Hôpitaux de Paris (138) · University Hospital, Grenoble (79) · University of Zurich (76) · ResMed (74) · Fisher and Paykel Healthcare (72) · Brigham and Women's Hospital (68) · Assiut University (58) · Mayo Clinic (55) · National Taiwan University Hospital (55) · Massachusetts General Hospital (52) · GlaxoSmithKline (49) · Riphah International University (49) · VA Office of Research and Development (49) · Hospices Civils de Lyon (45) · University Health Network, Toronto (45)
United States (2343) · France (894) · Canada (556) · China (487) · Turkey (Türkiye) (426) · United Kingdom (390) · Spain (360) · Germany (337) · Italy (330) · Brazil (267) · Switzerland (217) · Belgium (209) · Taiwan (202) · Egypt (174) · Australia (151)
Konrad E Bloch, MD (17) · Rodrigo Hoyos (14) · Silvia Ulrich (14) · Atul Malhotra, MD (11) · Davide Chiumello, MD (11) · Laurent Brochard, MD (10) · Massimo Antonelli, MD (10) · Silvia Ulrich, Prof. (10) · Silvia Ulrich, Prof. Dr. (10) · Talant M Sooronbaev, MD (10) · Ewan Goligher, MD, PhD (9)
PMID 26903337, PMID 10793162, PMID 25693014, PMID 22797452, PMID 23688302, PMID 34473343, PMID 27620287, PMID 30624279, PMID 11401896, PMID 12091180, PMID 19255741, PMID 20843245, PMID 25003980, PMID 25647235, PMID 27440140, PMID 33177145, PMID 34259448, PMID 34425070, PMID 34739082, PMID 38341938, PMID 10816184, PMID 1388792, PMID 15781100, PMID 16009843, PMID 17507545, PMID 18191684, PMID 20197533, PMID 22374920, PMID 23631814, PMID 23661689, PMID 25348130, PMID 25980660, PMID 25981908, PMID 26094920, PMID 26567858, PMID 27206567, PMID 27571048, PMID 27626706, PMID 27659698, PMID 27757516, PMID 27888609, PMID 27997805, PMID 28422025, PMID 28466461, PMID 29420341, PMID 30291378, PMID 305471, PMID 32167524, PMID 32171076, PMID 3230208
2018 (30), 2019 (23), 2023 (18), 2017 (14), 2015 (13), 2025 (12), U10HD021385 (10), U10HD027880 (10), 2009 (8), U10HD021397 (8), U10HD027853 (8), U10HD027871 (8), U10HD027904 (8), U10HD034216 (8), 2016 (7)