8 completed, 3 terminated, 2 not yet recruiting, 2 unknown. 7 Phase 4, 3 Phase 1, 2 Early Phase 1, 2 Not applicable, 2 Phase 3.
Follow Penicillin V: new trials by email Literature Review of Penicillin V trials Research Report on Penicillin V
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Penicillin to Prevent Early Rheumatic Heart Disease in School-Aged Children Oral Penicillin V - Rheumatic Heart Disease in Children | Phase 3 | Not yet recruiting | Children's Hospital Medical Center, Cincinnati | 9622 | 2027-02-01 | 2026-09-03 |
| Prophylaxis of Recurrent Erysipelas in Lower Limbs: compreSsion thErapy vs aNTibiotics and Compression Therapy. elastic stockings, Phenoxymethylpenicillin - Recurrent Erysipelas | Phase 4 | Not yet recruiting | University Hospital, Tours | 200 | 2026-04-01 | 2026-04-24 |
| GOALIE: Intramuscular vs. Enteral Penicillin Prophylaxis to Prevent Progression of Latent RHD Trial phenoxymethyl penicillin, intramuscular benzathine penicillin G (BPG) prophylaxis - Rheumatic Heart Disease | Phase 2 | Active not recruiting | Children's Hospital Medical Center, Cincinnati | 1004 | 2023-09-01 | 2026-10-19 |
| Effects of Phenoximethylpenicillin, Amoxicillin and Amoxicillin-clavulanic Acid on the Gut Microbiota Phenoxymethylpenicillin, Amoxicillin, Amoxicillin-clavulanic acid - Infectious Disease | Phase 4 | Completed | Uppsala University | 104 | 2019-09-10 | 2022-12-02 |
| Sore Throat in Primary Care - a Comparison of Phenoxymethylpenicillin and No Antibiotic Treatment Phenoxymethylpenicillin, No antibiotic treatment - Sore Throat, Tonsillitis | Phase 4 | Recruiting | Katarina Hedin | 260 | 2019-09-09 | 2024-12-04 |
| Minimally Invasive Sensing of Beta-lactam Antibiotics Phenoxymethyl Penicillin, Microneedle array - Healthy Volunteers | Phase 1 | Completed | Imperial College London | 11 | 2018-04-12 | 2024-03-27 |
| Peritonsillar Abscess: Aspiration Versus Tonsillectomy a Chaud Aspiration, Tonsillectomy a chaud, Penicillin V + metronidazol (Penicillin allergy: Clindamycin alone) - Peritonsillar Abscess | Not applicable | Unknown | Odense University Hospital | 128 | 2017-11-10 | 2017-11-09 |
| Penicillin for the Emergency Department Outpatient Treatment of CELLulitis Flucloxacillin, Phenoxymethylpenicillin, Placebo (for phenoxymethylpenicillin) - Cellulitis, Wound Infection | Phase 4 | Unknown | Royal College of Surgeons, Ireland | 414 | 2016-12-01 | 2016-10-04 |
| Zinc Supplementation in Children With Sickle Cell Disease in Western Kenya Zinc Sulfate Tablets, Standard of Care - Sickle Cell Disease, Zinc Deficiency | Not applicable | Completed | Lucas Otieno Tina, MD MSc | 40 | 2016-05-20 | 2017-09-26 |
| Study of 5 and 10 Days Treatment With Penicillin Against Sore Throat Caused by Streptococci Phenoxymethylpenicillin - Tonsillitis | Phase 4 | Completed | Ass. Prof. Katarina Hedin | 433 | 2015-09-01 | 2018-11-14 |
| Patients Response to Early Switch To Oral:Osteomyelitis Study oral antibiotics, intravenous antibiotics - Osteomyelitis | Early Phase 1 | Terminated | Julio Ramirez | 11 | 2014-03-06 | 2021-04-06 |
| Efficacy of High Doses Penicillin V Versus High Doses Amoxicillin in the Treatment of Non-severe Pneumonia. Penicillin V, Amoxicillin - Community-acquired Pneumonia (CAP) | Phase 3 | Terminated | Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina | 43 | 2013-11-05 | 2017-07-05 |
| A Pharmacokinetic and Pharmacodynamic Study of Phenoxymethylpenicillin for Children Phenoxymethylpenicillin - Phenoxymethylpenicillin | Phase 1 | Completed | University of Aarhus | 80 | 2012-01-01 | 2014-10-01 |
| Comparing 3 Antibiotic Regimes for Erythema Migrans in General Practice Doxycycline, Phenoxymethylpenicillin, Amoxicillin - Erythema Migrans, Erythema Chronicum Migrans | Phase 4 | Completed | Morten Lindbaek | 225 | 2011-06-01 | 2014-12-12 |
| Pentriox - Induction of Oxidative Stress Penicillin V, Trimethoprim, Placebo - Oxidative Stress | Phase 1 | Completed | Henrik Enghusen Poulsen | 90 | 2010-11-01 | 2014-07-11 |
| Oral Penicillin and Penicillin Levels in Venous Umbilical Cord Blood oral penicillin V - Group B Streptococcus | Early Phase 1 | Terminated | Corewell Health East | 25 | 2009-01-01 | 2016-11-04 |
| RCT to Investigate if Prophylactic Antibiotics Prevent Further Episodes of Cellulitis (Erysipelas) of the Leg Penicillin VK, placebo - Cellulitis/Erysipelas of the Leg | Phase 4 | Completed | University of Nottingham | 274 | 2006-07-01 | 2012-07-24 |
Cellulitis (2) · Rheumatic Heart Disease (2) · Tonsillitis (2) · Abscess (1) · Anemia, Sickle Cell (1) · Borrelia Infections (1) · Communicable Diseases (1) · Community-Acquired Pneumonia (1) · Erysipelas (1) · Erythema Chronicum Migrans (1) · Glossitis, Benign Migratory (1) · Infections (1) · Lyme Disease (1) · Lymphedema (1) · Osteomyelitis (1)
Children's Hospital Medical Center, Cincinnati (2) · Ass. Prof. Katarina Hedin (1) · Corewell Health East (1) · Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina (1) · Henrik Enghusen Poulsen (1) · Imperial College London (1) · Julio Ramirez (1) · Katarina Hedin (1) · Lucas Otieno Tina, MD MSc (1) · Morten Lindbaek (1) · Odense University Hospital (1) · Royal College of Surgeons, Ireland (1) · University Hospital, Tours (1) · University of Aarhus (1) · University of Nottingham (1)
Denmark (3) · Sweden (3) · Ireland (2) · Uganda (2) · United Kingdom (2) · United States (2) · France (1) · Norway (1) · Spain (1)
Abel Wakai, MD FRCEM (1) · Adrian Moughty (1) · Alison H Holmes, MD MPH MBBS (1) · Andrea Z Beaton (1) · Chris Luke (1) · Conor Deasy (1) · David Seligson, MD (1) · Henrik E Poulsen, MD (1) · Hywel Williams, Professor (1) · John E Uckele, MD (1) · Joselyn Rwebembera (1) · Joseph McKeever (1) · Julio Ramirez, MD (1) · Katarina Hedin, Ass Prof (1)
PMID 15276398, PMID 15840453, PMID 19588358, PMID 22530208, PMID 28836993, PMID 29505880, PMID 31585944, PMID 33323208, PMID 36368940, PMID 38797460, PMID 4902833, PMID 8948280
2019 (2), 2015 (1)