303 completed, 105 unknown, 39 recruiting, 27 terminated. 212 Phase 4, 120 Not applicable, 94 Phase 3, 49 Phase 2, 34 Phase 1.
Follow Amoxicillin: new trials by email Literature Review of Amoxicillin trials Research Report on Amoxicillin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing a Novel Combination Treatment (Arm D) Versus Standard of Care for Intensive Phase Treatment for Mycobacterium Abscessus Pulmonary Disease in People With or Without Cystic Fibrosis in the Finding the Optimal Regimen for Mycobacterium Abscessus Treatment (FORMaT) Adaptive Platform Trial Sulbactam 25mg/kg -Durlobactam 25mg/kg (Every 6 hours), Ceftriaxone for Injection, Amoxicillin - Mycobacterium Abscessus Pulmonary Disease, Mycobacterium Abscessus Infection | Phase 2 | Not yet recruiting | The University of Queensland | 300 | 2027-04-01 | 2026-03-20 |
| Comparison of Topical Antibiotics Versus Systemic Antibiotics in Preventing Burn Wound Infection in Pediatric Burn Patients Silver Sulfadiazine Cream 1%, Amoxicillin and clavulanate - Burn | Not applicable | Not yet recruiting | abdul mateen | 222 | 2026-11-05 | 2026-10-13 |
| Congenital Syphilis Treatment Trial (CONSISTENT) in Neonates Benzathine Penicillin, Amoxicillin - Syphilis, Congenital | Phase 4 | Not yet recruiting | University of Alabama at Birmingham | 374 | 2026-11-01 | 2026-09-02 |
| Efficacy and Safety of JP-1366-based Triple Therapy in Helicobacter Pylori-positive Subjects JP-1366 20 mg, Lansoprazole 30 mg Placebo, Clarithromycin 500mg, Amoxicillin 1000mg, Lansoprazole 30mg, JP-1366 20 mg Placebo, Clarithromycin 500mg, Amoxicillin 1000mg - H. Pylori Eradication Therapy | Phase 3 | Not yet recruiting | Onconic Therapeutics Inc. | 414 | 2026-11-01 | 2026-10-15 |
| Vonoprazan-Amoxicillin Dual Therapy for Helicobacter Pylori Infection in United States Adolescents Vonoprazan, Amoxicillin - Helicobacter Pylori Infection | Phase 2 | Not yet recruiting | Boston Children's Hospital | 55 | 2026-11-01 | 2026-10-06 |
| Vonoprazan High-Dose Dual VS Levofloxacin Concomitant Vonoprazan, Levofloxacin 500mg - Helicobacter Pylori Infection, Peptic Ulcer Disease | Phase 4 | Not yet recruiting | Damascus Hospital | 150 | 2026-11-01 | 2026-06-03 |
| Amoxicillin-clavulanate Versus Amoxicillin Versus Placebo in Acute Otitis Media in Children Amoxicillin, Amoxicillin + Clavulanate, Placebo - Acute Otitis Media, AOM - Acute Otitis Media | Phase 4 | Not yet recruiting | Kuopio University Hospital | 219 | 2026-11-01 | 2026-10-16 |
| Antibiotic Prophylaxis After Simple Tooth Extraction in Immunosuppressed Patients With Autoimmune Rheumatic Diseases Amoxicillin, Placebo - Autoimmune Rheumatic Diseases, Tooth Extraction | Phase 4 | Recruiting | University of Sao Paulo General Hospital | 352 | 2026-10-07 | 2026-10-15 |
| Comparative Effectiveness of Available Treatments for Sinus and Ear Infections in Children (Acute Sinusitis) Amoxicillin, Amoxi Clavulanate, Amoxicillin Placebo - ACUTE SINUSITIS, Sinusitis | Phase 4 | Recruiting | Nader Shaikh | 1100 | 2026-10-01 | 2026-10-20 |
| Comparative Effectiveness of Available Treatments for Sinus and Ear Infections in Children (Acute Otitis Media) Amoxicillin, Amoxicillin-Clavulanate, Amoxicillin Placebo - Acute Otitis Media (AOM) | Phase 4 | Recruiting | Nader Shaikh | 1100 | 2026-10-01 | 2026-10-20 |
| Comparative Efficacy of Amoxicillin, Metronidazole, and Chlorhexidine in Preventing Alveolar Osteitis Amoxicillin, Metronidazole, Chlorhexidine - Alveolar Osteitis | Not applicable | Not yet recruiting | Khyber Medical University Peshawar | 240 | 2026-09-25 | 2026-10-14 |
| Optimizing H. Pylori Eradication Regimen Under Intensified Acid Suppression Keverprazan Hydrochloride 20 mg TID, Minocycline 100 mg (10-Day Regimen), Keverprazan Hydrochloride 20 mg BID - HELICOBACTER PYLORI INFECTIONS | Phase 4 | Not yet recruiting | Qilu Hospital of Shandong University | 316 | 2026-08-01 | 2026-08-06 |
| 3 vs. 5 Days of Amoxicillin for Childhood Pneumonia: An RCT Amoxicillin - Community Acquired Pneumonia, Childhood Pneumonia | Early Phase 1 | Not yet recruiting | Khyber Teaching Hospital | 250 | 2026-06-01 | 2026-06-15 |
| Comprehensive Ambulatory Antibiotics for the Treatment of Congenital Syphilis Linezolid (LZD), Amoxicillin, Benzathine Penicillin G - Syphilis, Congenital | Phase 2 | Recruiting | London School of Hygiene and Tropical Medicine | 90 | 2026-05-04 | 2026-10-22 |
| Preoperative Versus Postoperative Amoxicillin in Impacted Third Molar Surgery Amoxicillin - Impacted Mandibular Third Molar, Impacted Mandibular Third Molar Extraction | Completed | Recep Tayyip Erdogan University | 52 | 2026-04-10 | 2026-10-05 | |
| Vonoprazan vs Proton Pump Inhibitor With Vitamin D or Probiotics Based Triple Therapy for Eradication of Helicobacter Pylori Infection Vonoparazan, Vitamin D, Probiotic - HELICOBACTER PYLORI INFECTIONS, Helicobacter Infection | Phase 2 | Recruiting | Tanta University | 132 | 2026-02-15 | 2026-09-09 |
| Comparative Study Evaluating Safety and Effectiveness of ( Proton Pump Inhibitor Versus Vonoprazan ) Based Triple Therapy With or Without Zinc to Eradicate H. Pylori Infection zinc sulfate, Vonoprazan + amoxicillin + clarithromycin, proton pump inhibitor + amoxicillin - HELICOBACTER PYLORI INFECTIONS | Phase 3 | Recruiting | Tanta University | 88 | 2026-02-01 | 2026-09-09 |
| Antibiotic Prophylaxis Versus Placebo in Alveolar Bone Grafting: A Randomized Controlled Trial Amoxicillin 500 mg (prophylactic regimen), Placebo Capsule (matched dosing schedule) - Alveolar Ridge Augmentation, Bone Grafting | Not applicable | Not yet recruiting | Agnaldo Rocha de Souza Junior | 150 | 2026-02-01 | 2025-12-29 |
| Clinical Trial to Evaluate the Efficacy of Probit-Based Triple Therapy for Helicobacter Pylori Eradication This study aims to evaluate the efficacy and safety of a 14-day triple therapy regimen consisting of Zastaprazan 20 mg, clarithromycin, and amoxicillin for the eradication of Helicobacter pylori. - Helicobacter Infection | Phase 4 | Not yet recruiting | Samsung Medical Center | 103 | 2025-12-01 | 2025-08-14 |
| Comparison of Two Treatment Regimens of Helicobacter Pylori Infection Clarithromycin, Levofloxacin - Helicobacter Pylori Infection | Phase 4 | Not yet recruiting | Rehman Medical Institute - RMI | 156 | 2025-12-01 | 2025-06-15 |
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Pneumonia (27) · Helicobacter Infections (19) · Gastritis (16) · Dyspepsia (13) · Infections (13) · Community-Acquired Pneumonia (12) · Peptic Ulcer (12) · Periodontitis (11) · Chronic Periodontitis (9) · Periodontal Diseases (9) · Otitis Media (8) · Severe Acute Malnutrition (8) · Stomach Neoplasms (8) · Sinusitis (7) · Aggressive Periodontitis (6)
Shandong University (17) · Shanghai Jiao Tong University School of Medicine (16) · Kaohsiung Veterans General Hospital. (12) · Xijing Hospital of Digestive Diseases (11) · National Taiwan University Hospital (10) · Washington University School of Medicine (8) · Nanjing First Hospital, Nanjing Medical University (7) · Aga Khan University (6) · Chang Gung Memorial Hospital (6) · Damascus Hospital (6) · Second Affiliated Hospital, Zhejiang University, School of Medicine (6) · Mackay Memorial Hospital (5) · Pfizer (5) · Seoul National University Bundang Hospital (5) · Shanghai Zhongshan Hospital (5)
China (93) · United States (71) · Taiwan (41) · Brazil (22) · South Korea (22) · Pakistan (20) · France (17) · Egypt (15) · Canada (13) · Spain (12) · Italy (10) · Malawi (9) · Germany (8) · Netherlands (7) · Turkey (Türkiye) (7)
Ping-I Hsu, Bachelor (8) · Xiuli Zuo, MD,PhD (7) · Hong Lu, M.D. (5) · Jyh-Chin Yang, M.D.Ph.D. (4) · Mark J Manary, MD (4) · Tai-cherng Liou, MD (4) · Yongquan Shi, Ph. D (4) · Zhenyu Zhang (4) · Marouf M Alhalabi, MD (3) · Taotao Liu, MD (3) · Amy Ginsburg, MD, MPH (2)
PMID 33197289, PMID 27707777, PMID 28456631, PMID 28303587, PMID 32348007, PMID 34836916, PMID 35012490, PMID 15371921, PMID 15691312, PMID 22285055, PMID 25741163, PMID 26285807, PMID 26935876, PMID 27029851, PMID 29914954, PMID 31111585, PMID 32365359, PMID 32545856, PMID 36403158, PMID 38359854, PMID 10086658, PMID 10219875, PMID 10555792, PMID 11197288, PMID 11294711, PMID 11957126, PMID 12039901, PMID 12384383, PMID 12439804, PMID 12603990, PMID 12704263, PMID 12722900, PMID 12787214, PMID 12963381, PMID 14663809, PMID 15173031, PMID 15273542, PMID 15276398, PMID 15530127, PMID 1559306, PMID 15620935, PMID 15840453, PMID 15907550, PMID 15909433, PMID 16174856, PMID 1622965, PMID 16337461, PMID 16437639, PMID 16441468, PMID 16546647
2014 (3), 2019 (3), 2008 (2), 2009 (1), 2018 (1), 2023 (1), 2025 (1), 4UH3DE031129-02 (1), P30CA016672 (1), R01DE014242 (1), R01HD111532 (1), R21HD100932 (1), U01AI064655 (1)