310 completed, 72 unknown, 54 terminated, 32 withdrawn. 145 Phase 3, 132 Phase 4, 116 Phase 2, 85 Not applicable, 55 Phase 1.
Follow Azithromycin: new trials by email Literature Review of Azithromycin trials Research Report on Azithromycin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparative Effectiveness of Roflumilast and Azithromycin in Reducing Exacerbations in Severe Chronic Obstructive Pulmonary Disease ( COPD ) Patients With Chronic Bronchitis Phenotype Roflumilast Oral Tablet, Azithromycin 250 mg - Chronic Obstructive Pulmonary Disease With Exacerbation | Phase 4 | Not yet recruiting | Sidra Aziz | 70 | 2027-02-01 | 2026-08-31 |
| Improving Management and Secondary Prevention Through Azithromycin Comparative Trial in Rheumatic Heart Disease in Nigeria)- IMPACT-RHD Nigeria Benzathine Penicillin, Azithromycin (Azithro) - Rheumatic Fever, Valvular Heart Diseases | Not applicable | Not yet recruiting | Ladoke Akintola University of Technology, Ogbomoso, Nigeria | 474 | 2027-01-05 | 2026-06-04 |
| Immunomodulatory Treatment of Interstitial Lung Disease Associated With Surfactant Related Gene Variants Azithromycin 250 mg x3/week (3 tablets/week), Prednisone 10 mg/day, Hydroxychloroquine 400 mg/day - Interstitial Lung Disease | Phase 2 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 30 | 2026-11-01 | 2026-09-22 |
| AUTOP 2: Screen-and-treat Strategy for Vaginal Flora Abnormalities by Molecular Biology in Pregnant Women at High Risk of Preterm Birth Vaginal flora abnormalities screening and quantification using molecular biology technique, Azithromycin, Ceftriaxone - Bacterial Vaginosis, Vaginal Dysbiosis | Phase 3 | Not yet recruiting | Assistance Publique Hopitaux De Marseille | 1794 | 2026-10-01 | 2026-08-27 |
| Effect of Post Operative Low Dose Oral Azithromycin in Chronic Rhinosinusitis Patients With Nasal Polyps Azithromycin, routine nasal douching - Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) | Phase 4 | Not yet recruiting | Assiut University | 52 | 2026-10-01 | 2026-08-21 |
| The Relapse to Acute Malnutrition Prevention (RAMP) Trial Azithromycin, Placebo (Azithromycin), Small-quantity Lipid-based Nutrient Supplements - Acute Malnutrition in Childhood, Acute Malnutrition, Severe | Not applicable | Not yet recruiting | Action Against Hunger USA | 3750 | 2026-10-01 | 2026-10-13 |
| Extended Azithromycin Treatment in Prelabor Rupture of Membranes Azithromycin (Azithro), Standard Azithromycin Dosing - Preterm Prelabor Rupture of Membranes, PPROM | Phase 4 | Recruiting | Alexa Henderson | 30 | 2026-08-19 | 2026-09-04 |
| Azithromycin in Atopic Dermatitis Betamethasone or tacrolimus ointments, Azithromycin - Atopic Dermatitis | Phase 4 | Not yet recruiting | Cairo University | 40 | 2026-08-01 | 2026-07-20 |
| Azithromycin to Modify Bronchiectasis Exacerbation Risk Standard Bronchiectasis Care, Azithromycin, Matching Placebo - Non-cystic Fibrosis Bronchiectasis, Bronchiectasis Adult | Phase 4 | Recruiting | Assiut University | 500 | 2026-06-29 | 2026-09-24 |
| Assessing the Impact of Unnecessary Antibiotic Treatment on the Development of Appropriate Adaptive Immune Responses in Malnourished Bangladeshi Infants Azithromycin - Antibiotic Resistance Prevention | Phase 1 | Not yet recruiting | University of Virginia | 150 | 2026-06-01 | 2026-06-01 |
| Enhanced Treatment Strategy for Disseminated MAC Infection in HIV Patients: A Randomized Controlled Trial Standard Triple Therapy, Experimental: Standard Triple Therapy Plus Fluoroquinolone - Opportunistic Infections, HIV Related, Disseminated Mycobacterium Avium Complex Infection | Not applicable | Not yet recruiting | Shanghai Public Health Clinical Center | 124 | 2026-04-30 | 2026-05-13 |
| The Impact of Shigellosis and Recommended Treatment in Children Azithromycin, Placebo - Diarrhea Infectious, Shigella | Phase 2 | Recruiting | Johns Hopkins Bloomberg School of Public Health | 700 | 2026-03-18 | 2026-03-30 |
| Doxycycline vs. Macrolide for MRMP (DOMINO) Doxycycline, Azithromycin - Mycoplasma Pneumoniae, Mycoplasma Pneumoniae Pneumonia | Phase 4 | Not yet recruiting | Young June Choe | 208 | 2026-03-01 | 2025-12-29 |
| PLatform for Adaptive Trials In Perinatal UnitS - [Core Protocol] Erythromycin, Amoxicillin and Erythromycin, Azithromycin - Preterm Birth | Not applicable | Not yet recruiting | University of Melbourne | 100000 | 2025-11-01 | 2025-06-13 |
| Adjunctive 308-nm Excimer Light With Oral Azithromycin for Inflammatory Acne 308-nm Excimer Light, Azithromycin - Acne Vulgaris | Not applicable | Completed | Mahmoud Rageh | 32 | 2025-10-12 | 2026-08-21 |
| Comparison of Efficacy of Azithromycin Alone vs Combination of Azithromycin and Probiotics in Management of Mild to Moderate Acne Vulgaris Azithromycin 250 MG Oral Capsule, Azithromycin 250 MG Oral Capsule Along with Oral Probiotics - Acne Vulgaris II or III Degree | Phase 4 | Active not recruiting | Hayatabad Medical Complex | 60 | 2025-10-12 | 2026-02-03 |
| Azithromycin Versus Doxycycline in Hospitalized Adult Patients With Community Acquired Pneumonia Treated With Beta-lactams Doxycycline, Azithromycin - Community-acquired Pneumonia | Phase 4 | Recruiting | Mayo Clinic | 1120 | 2025-09-15 | 2026-09-24 |
| Preterm Rupture of Membranes Optimising Antibiotics Trial Erythromycin 250mg + placebo, Azithromycin 500mg + placebo, Erythromycin 250mg and Amoxicillin 500mg - PPROM, Preterm | Not applicable | Not yet recruiting | University of Melbourne | 3900 | 2025-09-01 | 2025-04-02 |
| Individualizing Treatment for Asthma in Primary Care (Full Study) Inhaled corticosteroid (ICS), Azithromycin, Asthma Symptom Monitoring Web-based Application - Asthma, Asthma Attack | Phase 4 | Recruiting | DARTNet Institute | 3200 | 2025-08-01 | 2025-10-29 |
| Short-term Antibiotic Therapy in Mycobacterium Avium Complex Pulmonary Disease Contezolid, Azithromycin, Ethambutol (E) - Mycobacterium Avium Complex Pulmonary Disease | Phase 4 | Recruiting | Bin Cao | 188 | 2025-07-24 | 2025-10-09 |
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