1203 completed, 366 unknown, 224 recruiting, 128 terminated. 1001 Not applicable, 164 Phase 3, 154 Phase 2, 148 Phase 4, 105 Phase 1.
Follow Deglutition Disorders: new trials by email Literature Review of Deglutition Disorders trials Research Report on Deglutition Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AI-Enabled Mobile App for Safe Eating in Older Adults With Dysphagia AI-Enabled Mobile Application plus Standard Care, Standard Dysphagia Education - Deglutition Disorders, Dysphagia | Not applicable | Not yet recruiting | KAM Chi Shan Anna | 332 | 2028-01-01 | 2026-09-23 |
| Oral Fosamprenavir for GERD Fosamprenavir Calcium 700 MG Oral Tablet, Placebo - Refractory Gastroesophageal Reflux Disease, Gastroesophageal Reflux Disease | Phase 2 | Not yet recruiting | Medical College of Wisconsin | 60 | 2027-10-01 | 2026-09-10 |
| Optimizing Dysphagia Treatment Delivery in Acute Care: A Hybrid Efficacy Implementation Trial Expiratory muscle strength training (EMST), Standard of Care Dysphagia Treatment, Intensive Dysphagia Treatment - Dysphagia, Critical Illness | Not applicable | Not yet recruiting | Vanderbilt University Medical Center | 120 | 2027-07-01 | 2026-10-14 |
| Parent Implemented Oral Nutrition, Eating, and Esophageal Reflexes Reintegration Protocol: RCT PIONEER Protocol - Deglutition Disorders in Infants, Chronic Tube Feeding in Hospitalized Infants | Not applicable | Not yet recruiting | Nationwide Children's Hospital | 130 | 2027-07-01 | 2026-08-28 |
| Swallowing Impairments in ICU Survivors and Community-Dwelling Adults Dysphagia, Healthy Aging | Withdrawn | Vanderbilt University Medical Center | 2027-04-01 | 2026-06-02 | ||
| Maximizing Quality of Life After Cancer Through Rehabilitation TIMELY REHAB - Head and Neck Cancer, Hearing Loss | Not applicable | Not yet recruiting | VA Office of Research and Development | 74 | 2027-03-01 | 2026-06-03 |
| Interest of Telemedicine in Primary Care in an Multidisability Population Institutionalized Experimental procedure: swallowing assessment by telemedicine, Standard procedure: day hospitalization - Deglutition Disorders in Disabled Persons | Not applicable | Not yet recruiting | University Hospital, Toulouse | 62 | 2027-01-01 | 2026-08-28 |
| Endoscopic Band Ligation for Treating Reflux Disease Band Ligation - GERD | Not applicable | Not yet recruiting | El Katib Hospital | 10 | 2027-01-01 | 2026-09-10 |
| Exploring the Efficacy of the Effortful Swallow Maneuver for Improving Swallowing in People With PD Effortful swallow - Dysphagia, Parkinson Disease (PD) | Not applicable | Not yet recruiting | University of Alberta | 74 | 2027-01-01 | 2026-08-19 |
| Usefulness and Feasibility of Ultrasound in Office Laryngology Procedures Ultrasound for cough, Ultrasound for vocal fold atrophy or vocal fold paresis/paralysis, Ultrasound for dysphagia - Cough, Vocal Cord Atrophy | Not applicable | Not yet recruiting | Weill Medical College of Cornell University | 200 | 2027-01-01 | 2026-06-16 |
| Deep Brain Stimulation + Therapy for Stroke Boston Scientific Vercise Deep Brain Stimulation (DBS) System, Rehabilitation Training Protocol - Stroke, Dysarthria | Not applicable | Not yet recruiting | Pirondini, Elvira, PhD | 15 | 2027-01-01 | 2026-09-30 |
| Disposable Endoscope Platform in Third Space Endoscopic Procedures (Esophageal or Gastric) Per-Oral Endoscopic Myotomy - Achalasia, Gastroparesis | Withdrawn | Baylor College of Medicine | 2026-12-30 | 2026-10-01 | ||
| Effects of Different-Frequency Electroacupuncture on Suprahyoid Muscles in Post-Stroke Dysphagia: Efficacy and Neural Networks Low Frequency EA, Medium Frequency EA, High Frequency EA - Stroke Sequelae, Deglutition Disorders | Not applicable | Not yet recruiting | Kaili Chen | 102 | 2026-12-21 | 2026-09-24 |
| Pilot Study of Salivary Bile Acids and Pepsin as Predictive Biomarkers of Reflux Disease After Sleeve Gastrectomy Reflux Disease, Gastro-Esophageal, Sleeve Gastrectomy | Not yet recruiting | Hospital de Mataró | 60 | 2026-12-01 | 2026-05-26 | |
| PROPER-GERD: A Prospective Crossover Study to Evaluate Probe Placement Optimization for Reflux Testing in Women and Lower-BMI Patients Bravo pH monitoring sessions - GERD | Not applicable | Not yet recruiting | University of Chicago | 80 | 2026-12-01 | 2026-10-13 |
| PREcision MEDicine In Achalasia (PREMEDIA) - Cohort Type III Achalasia, EGJ Outflow Obstruction With Spastic/Hypercontractile Features | Recruiting | Northwestern University | 200 | 2026-12-01 | 2026-10-13 | |
| The Esophageal String Test as a Diagnostic Screening Tool for Eosinophilic Esophagitis Among Africans With Dysphagia in Mali and the United States Esophageal string test - Dysphagia, Eosinophilic Esophagitis | Not applicable | Recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 70 | 2026-11-08 | 2026-11-03 |
| EEG Feedback-Based Vagus Nerve Stimulation for Post-Stroke Dysphagia EEG Biofeedback-Guided taVNS, Conventional taVNS - Ischemic Stroke, Post-stroke Dysphagia | Not applicable | Not yet recruiting | First Affiliated Hospital of Fujian Medical University | 60 | 2026-11-01 | 2026-10-26 |
| A Prospective, Multicenter, Single-Arm Study to Support the Clinical Evidence Base for MRace as a Treatment Option for FMR Patients With Complex M-TEER Anatomies (AU) Transcatheter mitral valve repair - Mitral Valve (MV) Regurgitation | Not applicable | Not yet recruiting | Polares Medical SA | 15 | 2026-11-01 | 2026-08-11 |
| Gastroesophageal Reflux and Respiratory Function in Patients Undergoing Abdominoplasty Assessment of anthropometric and sociodemographic data and clinical history, Assessment of Symptoms, Quality of Life, and Physical Activity, Spirometric assessment - Abdominoplasty, Diaphragm | Not yet recruiting | Universidade Federal de Pernambuco | 30 | 2026-11-01 | 2026-10-16 |
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Gastroesophageal Reflux (1174) · Stroke (149) · Esophageal Achalasia (139) · Heartburn (93) · Barrett Esophagus (69) · Laryngopharyngeal Reflux (53) · Obesity (51) · Non-Erosive Reflux Disease (46) · Head and Neck Neoplasms (44) · Parkinson Disease (39) · Dyspepsia (38) · Esophagitis (37) · Hernia, Hiatal (37) · Esophageal Motility Disorders (35)
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PMID 20354937, PMID 1451966, PMID 17270511, PMID 19735233, PMID 21441148, PMID 22068665, PMID 22146488, PMID 22609984, PMID 10734019, PMID 16137276, PMID 18590344, PMID 18590345, PMID 19737151, PMID 20010088, PMID 21114792, PMID 21129076, PMID 21586712, PMID 21740077, PMID 23665071, PMID 23689261, PMID 23853213, PMID 25304129, PMID 25330784, PMID 25469569, PMID 25478944, PMID 25850008, PMID 25858519, PMID 26966356, PMID 27398981, PMID 27609778, PMID 27883209, PMID 28487349, PMID 28677236, PMID 29408585, PMID 29806864, PMID 30711626, PMID 30956054, PMID 33799960, PMID 35432994, PMID 35579516, PMID 36142680, PMID 36270615, PMID 8784314, PMID 9291902, PMID 10599620, PMID 10875990, PMID 11127145, PMID 11190378, PMID 11275880, PMID 11309186
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